-
1
-
-
82955165123
-
Gene therapy in the treatment of peripheral arterial disease
-
Mughal NA, Russell DA, Ponnambalam S, et al. Gene therapy in the treatment of peripheral arterial disease. Br J Surg 2012; 99(1): 6-15.
-
(2012)
Br J Surg
, vol.99
, Issue.1
, pp. 6-15
-
-
Mughal, N.A.1
Russell, D.A.2
Ponnambalam, S.3
-
2
-
-
33845241195
-
Inter-society consensus for the management of peripheral arterial disease (TASC II)
-
Norgren L, Hiatt WR, Dormandy JA, et al. Inter-society consensus for the management of peripheral arterial disease (TASC II). Eur J Vasc Endovasc Surg 2007; 33(Suppl 1): S1-75.
-
(2007)
Eur J Vasc Endovasc Surg
, vol.33
, pp. S1-S75
-
-
Norgren, L.1
Hiatt, W.R.2
Dormandy, J.A.3
-
3
-
-
7944222302
-
Gene therapy for cardiovascular disease: The potential of VEGF
-
Tiong A, Freedman SB. Gene therapy for cardiovascular disease: the potential of VEGF. Curr Opin Mol Ther 2004; 6(2): 151-9.
-
(2004)
Curr Opin Mol Ther
, vol.6
, Issue.2
, pp. 151-159
-
-
Tiong, A.1
Freedman, S.B.2
-
4
-
-
84872054233
-
Executive summary: Heart disease and stroke statistics: 2013 update. A report from the American Heart Association
-
Go AS, Mozaffarian D, Roger VL, et al. Executive summary: heart disease and stroke statistics: 2013 update. A report from the American Heart Association. Circulation 2013; 127(1): 143-52.
-
(2013)
Circulation
, vol.127
, Issue.1
, pp. 143-152
-
-
Go, A.S.1
Mozaffarian, D.2
Roger, V.L.3
-
5
-
-
84862540404
-
Insights into gene therapy for critical limb ischemia: The devil is in the details
-
Madonna R, Rokosh G. Insights into gene therapy for critical limb ischemia: the devil is in the details. Vascul Pharmacol 2012; 57(1): 10-4.
-
(2012)
Vascul Pharmacol
, vol.57
, Issue.1
, pp. 10-14
-
-
Madonna, R.1
Rokosh, G.2
-
6
-
-
33947698754
-
Peripheral arterial occlusive disease: Magnetic resonance imaging and the role of aggressive medical management
-
Lumsden AB, Rice TW, Chen C, et al. Peripheral arterial occlusive disease: magnetic resonance imaging and the role of aggressive medical management. World J Surg 2007; 31(4): 695-704.
-
(2007)
World J Surg
, vol.31
, Issue.4
, pp. 695-704
-
-
Lumsden, A.B.1
Rice, T.W.2
Chen, C.3
-
7
-
-
84870919920
-
Measurement and interpretation of the ankle-brachial index: A scientific statement from the American Heart Association
-
Aboyans V, Criqui MH, Abraham P, et al. Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association. Circulation 2012; 126(24): 2890-909.
-
(2012)
Circulation
, vol.126
, Issue.24
, pp. 2890-2909
-
-
Aboyans, V.1
Criqui, M.H.2
Abraham, P.3
-
9
-
-
0028344109
-
Therapeutic angiogenesis: A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model
-
Takeshita S, Zheng LP, Brogi E, et al. Therapeutic angiogenesis: a single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest 1994; 93(2): 662-70.
-
(1994)
J Clin Invest
, vol.93
, Issue.2
, pp. 662-670
-
-
Takeshita, S.1
Zheng, L.P.2
Brogi, E.3
-
10
-
-
82855161421
-
Gene therapy in vascular disease
-
Sedighiani F, Nikol S. Gene therapy in vascular disease. Surgeon 2011; 9(6): 326-35.
-
(2011)
Surgeon
, vol.9
, Issue.6
, pp. 326-335
-
-
Sedighiani, F.1
Nikol, S.2
-
11
-
-
84879547051
-
Critical limb ischemia: Cell and molecular therapies for limb salvage
-
Davies MG. Critical limb ischemia: cell and molecular therapies for limb salvage. Methodist Debakey Cardiovasc J 2012; 8(4): 20-7.
-
(2012)
Methodist Debakey Cardiovasc J
, vol.8
, Issue.4
, pp. 20-27
-
-
Davies, M.G.1
-
12
-
-
84864238156
-
Medical therapy in peripheral artery disease
-
Berger JS, Hiatt WR. Medical therapy in peripheral artery disease. Circulation 2012; 126(4): 491-500.
-
(2012)
Circulation
, vol.126
, Issue.4
, pp. 491-500
-
-
Berger, J.S.1
Hiatt, W.R.2
-
13
-
-
70449499017
-
Regenerative therapy in peripheral artery disease
-
Germani A, Di Campli C, Pompilio G, et al. Regenerative therapy in peripheral artery disease. Cardiovasc Ther 2009; 27(4): 289-304.
-
(2009)
Cardiovasc Ther
, vol.27
, Issue.4
, pp. 289-304
-
-
Germani, A.1
Di Campli, C.2
Pompilio, G.3
-
14
-
-
0032583951
-
Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
-
Baumgartner I, Pieczek A, Manor O, et al. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 1998; 97(12): 1114-23.
-
(1998)
Circulation
, vol.97
, Issue.12
, pp. 1114-1123
-
-
Baumgartner, I.1
Pieczek, A.2
Manor, O.3
-
15
-
-
84879886685
-
Therapeutic angiogenesis for revascularization in peripheral artery disease
-
Grochot-Przeczek A, Dulak J, Jozkowicz A. Therapeutic angiogenesis for revascularization in peripheral artery disease. Gene 2013; 525(2): 220-8.
-
(2013)
Gene
, vol.525
, Issue.2
, pp. 220-228
-
-
Grochot-Przeczek, A.1
Dulak, J.2
Jozkowicz, A.3
-
16
-
-
15844420661
-
Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb
-
Isner JM, Pieczek A, Schainfeld R, et al. Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996; 348(9024): 370-4.
-
(1996)
Lancet
, vol.348
, Issue.9024
, pp. 370-374
-
-
Isner, J.M.1
Pieczek, A.2
Schainfeld, R.3
-
17
-
-
84878981581
-
From bench to bedside: Review of gene and cell-based therapies and the slow advancement into phase 3 clinical trials, with a focus on Aastrom's Ixmyelocel-T
-
Bartel RL, Booth E, Cramer C, et al. From bench to bedside: review of gene and cell-based therapies and the slow advancement into phase 3 clinical trials, with a focus on Aastrom's Ixmyelocel-T. Stem Cell Rev 2013; 9(3): 373-83.
-
(2013)
Stem Cell Rev
, vol.9
, Issue.3
, pp. 373-383
-
-
Bartel, R.L.1
Booth, E.2
Cramer, C.3
-
18
-
-
84861833505
-
Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease
-
Ouma GO, Jonas RA, Usman MH, et al. Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease. Vasc Med 2012; 17(3): 174-92.
-
(2012)
Vasc Med
, vol.17
, Issue.3
, pp. 174-192
-
-
Ouma, G.O.1
Jonas, R.A.2
Usman, M.H.3
-
19
-
-
84862026102
-
VEGF gene therapy: Therapeutic angiogenesis in the clinic and beyond
-
Giacca M, Zacchigna S. VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond. Gene Ther 2012; 19(6): 622-9.
-
(2012)
Gene Ther
, vol.19
, Issue.6
, pp. 622-629
-
-
Giacca, M.1
Zacchigna, S.2
-
20
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995; 146(5): 1029-39.
-
(1995)
Am J Pathol
, vol.146
, Issue.5
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
-
21
-
-
70350439869
-
VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGFB
-
Onimaru M, Yonemitsu Y, Fujii T, et al. VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGFB. Am J Physiol Heart Circ Physiol 2009; 297(5): H1685-96.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.5
, pp. H1685-H1696
-
-
Onimaru, M.1
Yonemitsu, Y.2
Fujii, T.3
-
22
-
-
0036556877
-
VEGF gene therapy for coronary artery disease and peripheral vascular disease
-
Rasmussen HS, Rasmussen CS, Macko J. VEGF gene therapy for coronary artery disease and peripheral vascular disease. Cardiovasc Radiat Med 2002; 3(2): 114-7.
-
(2002)
Cardiovasc Radiat Med
, vol.3
, Issue.2
, pp. 114-117
-
-
Rasmussen, H.S.1
Rasmussen, C.S.2
Macko, J.3
-
23
-
-
33750480535
-
Magnetic resonance angiography reveals therapeutic enlargement of collateral vessels induced by VEGF in a murine model of peripheral arterial disease
-
Greve JM, Chico TJ, Goldman H, et al. Magnetic resonance angiography reveals therapeutic enlargement of collateral vessels induced by VEGF in a murine model of peripheral arterial disease. J Magn Reson Imaging 2006; 24(5): 1124-32.
-
(2006)
J Magn Reson Imaging
, vol.24
, Issue.5
, pp. 1124-1132
-
-
Greve, J.M.1
Chico, T.J.2
Goldman, H.3
-
24
-
-
58849151759
-
Recombinant adenoassociated virus-based gene transfer of cathelicidin induces therapeutic neovascularization preferentially via potent collateral growth
-
Pinkenburg O, Pfosser A, Hinkel R, et al. Recombinant adenoassociated virus-based gene transfer of cathelicidin induces therapeutic neovascularization preferentially via potent collateral growth. Hum Gene Ther 2009; 20(2): 159-67.
-
(2009)
Hum Gene Ther
, vol.20
, Issue.2
, pp. 159-167
-
-
Pinkenburg, O.1
Pfosser, A.2
Hinkel, R.3
-
25
-
-
67349183987
-
Repeated, but not single, VEGF gene transfer affords protection against ischemic muscle lesions in rabbits with hindlimb ischemia
-
Olea FD, Vera Janavel G, Cuniberti L, et al. Repeated, but not single, VEGF gene transfer affords protection against ischemic muscle lesions in rabbits with hindlimb ischemia. Gene Ther 2009; 16(6): 716-23.
-
(2009)
Gene Ther
, vol.16
, Issue.6
, pp. 716-723
-
-
Olea, F.D.1
Vera Janavel, G.2
Cuniberti, L.3
-
26
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
Rebar EJ, Huang Y, Hickey R, et al. Induction of angiogenesis in a mouse model using engineered transcription factors. Nat Med 2002; 8(12): 1427-32.
-
(2002)
Nat Med
, vol.8
, Issue.12
, pp. 1427-1432
-
-
Rebar, E.J.1
Huang, Y.2
Hickey, R.3
-
27
-
-
0036710478
-
Designed transcription factors as tools for therapeutics and functional genomics
-
Urnov FD, Rebar EJ. Designed transcription factors as tools for therapeutics and functional genomics. Biochem Pharmacol 2002; 64: 919-23.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 919-923
-
-
Urnov, F.D.1
Rebar, E.J.2
-
28
-
-
0035815697
-
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A
-
Liu PQ, Rebar EJ, Zhang L, et al. Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J Biol Chem 2001; 276: 11323-34.
-
(2001)
J Biol Chem
, vol.276
, pp. 11323-11334
-
-
Liu, P.Q.1
Rebar, E.J.2
Zhang, L.3
-
29
-
-
9144250992
-
Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors
-
Snowden AW, Zhang L, Urnov F, et al. Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. Cancer Res 2003; 63: 8968-76.
-
(2003)
Cancer Res
, vol.63
, pp. 8968-8976
-
-
Snowden, A.W.1
Zhang, L.2
Urnov, F.3
-
30
-
-
34548509209
-
Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors
-
Dent CL, Lau G, Drake EA, et al. Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors. Gene Ther 2007; 14: 1362-69.
-
(2007)
Gene Ther
, vol.14
, pp. 1362-1369
-
-
Dent, C.L.1
Lau, G.2
Drake, E.A.3
-
31
-
-
6444236227
-
Engineered zinc fingeractivating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia
-
Dai Q, Huang J, Klitzman B, et al. Engineered zinc fingeractivating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. Circulation 2004; 110: 2467-75.
-
(2004)
Circulation
, vol.110
, pp. 2467-2475
-
-
Dai, Q.1
Huang, J.2
Klitzman, B.3
-
32
-
-
33745651801
-
An engineeered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia
-
Xie D, Li Y, Reed EA, et al. An engineeered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia. J Vasc Surg 2006; 44: 165-75.
-
(2006)
J Vasc Surg
, vol.44
, pp. 165-175
-
-
Xie, D.1
Li, Y.2
Reed, E.A.3
-
33
-
-
33847400644
-
In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia
-
Li Y, Hazarika S, Xie D, et al. In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia. Diabetes 2007; 56: 656-65.
-
(2007)
Diabetes
, vol.56
, pp. 656-665
-
-
Li, Y.1
Hazarika, S.2
Xie, D.3
-
34
-
-
18744367228
-
Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle
-
Gounis MJ, Spiga MG, Graham RM, et al. Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle. Gene Ther 2005; 12(9): 762-71.
-
(2005)
Gene Ther
, vol.12
, Issue.9
, pp. 762-771
-
-
Gounis, M.J.1
Spiga, M.G.2
Graham, R.M.3
-
35
-
-
0034255465
-
Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia
-
Gowdak LH, Poliakova L, Wang X, et al. Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia. Circulation 2000; 102(5): 565-71.
-
(2000)
Circulation
, vol.102
, Issue.5
, pp. 565-571
-
-
Gowdak, L.H.1
Poliakova, L.2
Wang, X.3
-
36
-
-
0035004884
-
Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia
-
Simovic D, Isner JM, Ropper AH, et al. Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia. Arch Neurol 2001; 58(5): 761-8.
-
(2001)
Arch Neurol
, vol.58
, Issue.5
, pp. 761-768
-
-
Simovic, D.1
Isner, J.M.2
Ropper, A.H.3
-
37
-
-
4644292454
-
Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease
-
Kim HJ, Jang SY, Park JI, et al. Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease. Exp Mol Med 2004; 36(4): 336-44.
-
(2004)
Exp Mol Med
, vol.36
, Issue.4
, pp. 336-344
-
-
Kim, H.J.1
Jang, S.Y.2
Park, J.I.3
-
38
-
-
0037313811
-
Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia
-
Shyu KG, Chang H, Wang BW, et al. Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia. Am J Med 2003; 114(2): 85-92.
-
(2003)
Am J Med
, vol.114
, Issue.2
, pp. 85-92
-
-
Shyu, K.G.1
Chang, H.2
Wang, B.W.3
-
39
-
-
33745643590
-
Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: A double-blind randomized trial
-
Kusumanto YH, van Weel V, Mulder NH, et al. Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: a double-blind randomized trial. Hum Gene Ther 2006; 17(6): 683-91.
-
(2006)
Hum Gene Ther
, vol.17
, Issue.6
, pp. 683-691
-
-
Kusumanto, Y.H.1
van Weel, V.2
Mulder, N.H.3
-
40
-
-
0036665610
-
Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: A randomized, placebocontrolled, double-blinded phase II study
-
Makinen K, Manninen H, Hedman M, et al. Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebocontrolled, double-blinded phase II study. Mol Ther 2002; 6(1): 127-33.
-
(2002)
Mol Ther
, vol.6
, Issue.1
, pp. 127-133
-
-
Makinen, K.1
Manninen, H.2
Hedman, M.3
-
41
-
-
0035859782
-
Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve
-
Rajagopalan S, Shah M, Luciano A, et al. Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve. Circulation 2001; 104(7): 753-5.
-
(2001)
Circulation
, vol.104
, Issue.7
, pp. 753-755
-
-
Rajagopalan, S.1
Shah, M.2
Luciano, A.3
-
42
-
-
0036710990
-
Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication
-
Rajagopalan S, Trachtenberg J, Mohler E, et al. Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication. Am J Cardiol 2002; 90(5): 512-6.
-
(2002)
Am J Cardiol
, vol.90
, Issue.5
, pp. 512-516
-
-
Rajagopalan, S.1
Trachtenberg, J.2
Mohler, E.3
-
43
-
-
0142023866
-
Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
-
Rajagopalan S, Mohler III ER, Lederman RJ, et al. Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 2003; 108(16): 1933-8.
-
(2003)
Circulation
, vol.108
, Issue.16
, pp. 1933-1938
-
-
Rajagopalan, S.1
Mohler, E.R.2
Lederman, R.J.3
-
44
-
-
18144364350
-
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis
-
Presta M, Dell’Era P, Mitola S, et al. Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev 2005; 16(2): 159-78.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, Issue.2
, pp. 159-178
-
-
Presta, M.1
Dell’Era, P.2
Mitola, S.3
-
45
-
-
33744476943
-
Intramuscular gene transfer of fibroblast growth factor-1 using improved pCOR plasmid design stimulates collateral formation in a rabbit ischemic hindlimb model
-
Witzenbichler B, Mahfoudi A, Soubrier F, et al. Intramuscular gene transfer of fibroblast growth factor-1 using improved pCOR plasmid design stimulates collateral formation in a rabbit ischemic hindlimb model. J Mol Med 2006; 84(6): 491-502.
-
(2006)
J Mol Med
, vol.84
, Issue.6
, pp. 491-502
-
-
Witzenbichler, B.1
Mahfoudi, A.2
Soubrier, F.3
-
46
-
-
0030778673
-
Arterial gene transfer of acidic fibroblast growth factor for therapeutic angiogenesis in vivo: Critical role of secretion signal in use of naked DNA
-
Tabata H. Arterial gene transfer of acidic fibroblast growth factor for therapeutic angiogenesis in vivo: critical role of secretion signal in use of naked DNA. Cardiovasc Res 1997; 35(3): 470-9.
-
(1997)
Cardiovasc Res
, vol.35
, Issue.3
, pp. 470-479
-
-
Tabata, H.1
-
47
-
-
13644281395
-
Human FGF-1 gene transfer promotes the formation of collateral vessels and arterioles in ischemic muscles of hypercholesterolemic hamsters
-
Caron A, Michelet S, Caron A, et al. Human FGF-1 gene transfer promotes the formation of collateral vessels and arterioles in ischemic muscles of hypercholesterolemic hamsters. J Gene Med 2004; 6(9): 1033-45.
-
(2004)
J Gene Med
, vol.6
, Issue.9
, pp. 1033-1045
-
-
Caron, A.1
Michelet, S.2
Caron, A.3
-
48
-
-
19044389402
-
Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of endstage unreconstructible lower extremity ischemia: Preliminary results of a phase I trial
-
Comerota AJ, Throm RC, Miller KA, et al. Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of endstage unreconstructible lower extremity ischemia: preliminary results of a phase I trial. J Vasc Surg 2002; 35(5): 930-6.
-
(2002)
J Vasc Surg
, vol.35
, Issue.5
, pp. 930-936
-
-
Comerota, A.J.1
Throm, R.C.2
Miller, K.A.3
-
49
-
-
67349276653
-
Local gene transfer and expression following intramuscular administration of FGF-1 plasmid DNA in patients with critical limb ischemia
-
Baumgartner I, Chronos N, Comerota A, et al. Local gene transfer and expression following intramuscular administration of FGF-1 plasmid DNA in patients with critical limb ischemia. Mol Ther 2009; 17(5): 914-21.
-
(2009)
Mol Ther
, vol.17
, Issue.5
, pp. 914-921
-
-
Baumgartner, I.1
Chronos, N.2
Comerota, A.3
-
50
-
-
42549140599
-
Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemia
-
Nikol S, Baumgartner I, Belle EV, et al. Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemia. Mol Ther 2008; 16(5): 972-8.
-
(2008)
Mol Ther
, vol.16
, Issue.5
, pp. 972-978
-
-
Nikol, S.1
Baumgartner, I.2
Belle, E.V.3
-
51
-
-
84858007033
-
Long-term safety of intramuscular gene transfer of non-viral FGF1 for peripheral artery disease
-
Niebuhr A, Henry T, Goldman J, et al. Long-term safety of intramuscular gene transfer of non-viral FGF1 for peripheral artery disease. Gene Ther 2012; 19(3): 264-70.
-
(2012)
Gene Ther
, vol.19
, Issue.3
, pp. 264-270
-
-
Niebuhr, A.1
Henry, T.2
Goldman, J.3
-
52
-
-
77957309846
-
Riferminogene pecaplasmide
-
Adis R&D Profile. Riferminogene pecaplasmide. Am J Cardiovasc Drugs 2010; 10(5): 343-6.
-
(2010)
Am J Cardiovasc Drugs
, vol.10
, Issue.5
, pp. 343-346
-
-
Adis, R.1
Profile, D.2
-
53
-
-
79958118819
-
Effect of fibroblast growth factor NV1FGF on amputation and death: A randomised placebocontrolled trial of gene therapy in critical limb ischaemia
-
Belch J, Hiatt WR, Baumgartner I, et al. Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebocontrolled trial of gene therapy in critical limb ischaemia. Lancet 2011; 377(9781): 1929-37.
-
(2011)
Lancet
, vol.377
, Issue.9781
, pp. 1929-1937
-
-
Belch, J.1
Hiatt, W.R.2
Baumgartner, I.3
-
54
-
-
0033820196
-
Basic fibroblast growth factor in patients with intermittent claudication: Results of a phase I trial
-
Lazarous DF, Unger EF, Epstein SE, et al. Basic fibroblast growth factor in patients with intermittent claudication: results of a phase I trial. J Am Coll Cardiol 2000; 36(4): 1239-44.
-
(2000)
J Am Coll Cardiol
, vol.36
, Issue.4
, pp. 1239-1244
-
-
Lazarous, D.F.1
Unger, E.F.2
Epstein, S.E.3
-
55
-
-
0037097035
-
Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): A randomised trial
-
Lederman RJ, Mendelsohn FO, Anderson RD, et al. Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial. Lancet 2002; 359(9323): 2053-8.
-
(2002)
Lancet
, vol.359
, Issue.9323
, pp. 2053-2058
-
-
Lederman, R.J.1
Mendelsohn, F.O.2
Anderson, R.D.3
-
56
-
-
0242660995
-
Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2)
-
Aviles RJ, Annex BH, Lederman RJ. Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2). Br J Pharmacol 2003; 140(4): 637-46.
-
(2003)
Br J Pharmacol
, vol.140
, Issue.4
, pp. 637-646
-
-
Aviles, R.J.1
Annex, B.H.2
Lederman, R.J.3
-
57
-
-
33750214507
-
Nonendothelial mesenchymal cell-derived MCP-1 is required for FGF-2-mediated therapeutic neovascularization: Critical role of the inflammatory/arteriogenic pathway
-
Fujii T, Yonemitsu Y, Onimaru M, et al. Nonendothelial mesenchymal cell-derived MCP-1 is required for FGF-2-mediated therapeutic neovascularization: critical role of the inflammatory/arteriogenic pathway. Arterioscler Thromb Vasc Biol 2006; 26(11): 2483-9.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, Issue.11
, pp. 2483-2489
-
-
Fujii, T.1
Yonemitsu, Y.2
Onimaru, M.3
-
58
-
-
2442694008
-
Essential role of PDGFRalpha-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo: Role of PDGFRalpha during angiogenesis
-
Tsutsumi N, Yonemitsu Y, Shikada Y, et al. Essential role of PDGFRalpha-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo: role of PDGFRalpha during angiogenesis. Circ Res 2004; 94(9): 1186-94.
-
(2004)
Circ Res
, vol.94
, Issue.9
, pp. 1186-1194
-
-
Tsutsumi, N.1
Yonemitsu, Y.2
Shikada, Y.3
-
59
-
-
78650897908
-
Synergistic angiogenic effect of codelivering fibroblast growth factor 2 and granulocyte-colony stimulating factor from fibrin scaffolds and bone marrow transplantation in critical limb ischemia
-
Layman H, Rahnemai-Azar AA, Pham SM, et al. Synergistic angiogenic effect of codelivering fibroblast growth factor 2 and granulocyte-colony stimulating factor from fibrin scaffolds and bone marrow transplantation in critical limb ischemia. Tissue Eng Part A 2011; 17(1-2): 243-54.
-
(2011)
Tissue Eng Part A
, vol.17
, Issue.1-2
, pp. 243-254
-
-
Layman, H.1
Rahnemai-Azar, A.A.2
Pham, S.M.3
-
60
-
-
0032713818
-
Adenovirus-mediated acidic fibroblast growth factor gene transfer induces angiogenesis in the nonischemic rabbit heart
-
Safi Jr J, DiPaula Jr AF, Riccioni T, et al. Adenovirus-mediated acidic fibroblast growth factor gene transfer induces angiogenesis in the nonischemic rabbit heart. Microvasc Res 1999; 58(3): 238-49.
-
(1999)
Microvasc Res
, vol.58
, Issue.3
, pp. 238-249
-
-
Safi, J.1
DiPaula, A.F.2
Riccioni, T.3
-
61
-
-
56349147736
-
Co-delivery of FGF-2 and G-CSF from gelatin-based hydrogels as angiogenic therapy in a murine critical limb ischemic model
-
Layman H, Sacasa M, Murphy AE, et al. Co-delivery of FGF-2 and G-CSF from gelatin-based hydrogels as angiogenic therapy in a murine critical limb ischemic model. Acta Biomater 2009; 5(1): 230-9.
-
(2009)
Acta Biomater
, vol.5
, Issue.1
, pp. 230-239
-
-
Layman, H.1
Sacasa, M.2
Murphy, A.E.3
-
62
-
-
33847654322
-
The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model
-
Layman H, Spiga MG, Brooks T, et al. The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model. Biomaterials 2007; 28(16): 2646-54.
-
(2007)
Biomaterials
, vol.28
, Issue.16
, pp. 2646-2654
-
-
Layman, H.1
Spiga, M.G.2
Brooks, T.3
-
63
-
-
0034425984
-
Efficient gene transfer to airway epithelium using recombinant Sendai virus
-
Yonemitsu Y, Kitson C, Ferrari S, et al. Efficient gene transfer to airway epithelium using recombinant Sendai virus. Nat Biotechnol 2000; 18(9): 970-3.
-
(2000)
Nat Biotechnol
, vol.18
, Issue.9
, pp. 970-973
-
-
Yonemitsu, Y.1
Kitson, C.2
Ferrari, S.3
-
64
-
-
0037662951
-
Intramuscular gene transfer of FGF-2 attenuates endothelial dysfunction and inhibits intimal hyperplasia of vein grafts in poor-runoff limbs of rabbit
-
Shoji T, Yonemitsu Y, Komori K, et al. Intramuscular gene transfer of FGF-2 attenuates endothelial dysfunction and inhibits intimal hyperplasia of vein grafts in poor-runoff limbs of rabbit. Am J Physiol Heart Circ Physiol 2003; 285(1): H173-82.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
, Issue.1
, pp. H173-H182
-
-
Shoji, T.1
Yonemitsu, Y.2
Komori, K.3
-
65
-
-
0037112560
-
Fibroblast growth factor-2 gene transfer can stimulate hepatocyte growth factor expression irrespective of hypoxia-mediated downregulation in ischemic limbs
-
Onimaru M, Yonemitsu Y, Tanii M, et al. Fibroblast growth factor-2 gene transfer can stimulate hepatocyte growth factor expression irrespective of hypoxia-mediated downregulation in ischemic limbs. Circ Res 2002; 91(10): 923-30.
-
(2002)
Circ Res
, vol.91
, Issue.10
, pp. 923-930
-
-
Onimaru, M.1
Yonemitsu, Y.2
Tanii, M.3
-
66
-
-
0037123968
-
Angiogenic gene therapy for experimental critical limb ischemia: Acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2
-
Masaki I, Yonemitsu Y, Yamashita A, et al. Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2. Circ Res 2002; 90(9): 966-73.
-
(2002)
Circ Res
, vol.90
, Issue.9
, pp. 966-973
-
-
Masaki, I.1
Yonemitsu, Y.2
Yamashita, A.3
-
67
-
-
84875230671
-
DVC1-0101 to treat peripheral arterial disease: A phase I/IIa open-label dose-escalation clinical trial
-
Yonemitsu Y, Matsumoto T, Itoh H, et al. DVC1-0101 to treat peripheral arterial disease: a phase I/IIa open-label dose-escalation clinical trial. Mol Ther 2013; 21(3): 707-14.
-
(2013)
Mol Ther
, vol.21
, Issue.3
, pp. 707-714
-
-
Yonemitsu, Y.1
Matsumoto, T.2
Itoh, H.3
-
68
-
-
85038654362
-
Efficacy and safety of DVC1-0101 for intermittent claudication secondary to peripheral artery disease: Study protocol of a randomized phase IIb trial
-
Tanaka M, Matsumoto T. Morisaki K, et al. Efficacy and safety of DVC1-0101 for intermittent claudication secondary to peripheral artery disease: study protocol of a randomized phase IIb trial. J Clin Trials 2012; 3: 138.
-
(2012)
J Clin Trials
, vol.3
, pp. 138
-
-
Tanaka, M.1
Matsumoto, T.2
Morisaki, K.3
-
69
-
-
0029985372
-
Emerging multipotent aspects of hepatocyte growth factor
-
Matsumoto K, Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J Biochem 1996; 119(4): 591-600.
-
(1996)
J Biochem
, vol.119
, Issue.4
, pp. 591-600
-
-
Matsumoto, K.1
Nakamura, T.2
-
70
-
-
0026722243
-
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
-
Bussolino F, Di Renzo MF, Ziche M, et al. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 1992; 119(3): 629-41.
-
(1992)
J Cell Biol
, vol.119
, Issue.3
, pp. 629-641
-
-
Bussolino, F.1
Di Renzo, M.F.2
Ziche, M.3
-
71
-
-
68549122767
-
Hepatocyte growth factor plays a critical role in the regulation of cytokine production and induction of endothelial progenitor cell mobilization: A pilot gene therapy study in patients with coronary heart disease
-
Yang ZJ, Xu SL, Chen B, et al. Hepatocyte growth factor plays a critical role in the regulation of cytokine production and induction of endothelial progenitor cell mobilization: a pilot gene therapy study in patients with coronary heart disease. Clin Exp Pharmacol Physiol 2009; 36(8): 790-6.
-
(2009)
Clin Exp Pharmacol Physiol
, vol.36
, Issue.8
, pp. 790-796
-
-
Yang, Z.J.1
Xu, S.L.2
Chen, B.3
-
72
-
-
0036022449
-
Hepatocyte growth factor as cardiovascular hormone: Role of HGF in the pathogenesis of cardiovascular disease
-
Morishita R, Aoki M, Yo Y, Ogihara T. Hepatocyte growth factor as cardiovascular hormone: role of HGF in the pathogenesis of cardiovascular disease. Endocrine J 2002; 49(3): 273-84.
-
(2002)
Endocrine J
, vol.49
, Issue.3
, pp. 273-284
-
-
Morishita, R.1
Aoki, M.2
Yo, Y.3
Ogihara, T.4
-
73
-
-
84881309158
-
Hepatocyte growth factor genemodified bone marrow-derived mesenchymal stem cells transplantation promotes angiogenesis in a rat model of hindlimb ischemia
-
Su GH, Sun YF, Lu YX, et al. Hepatocyte growth factor genemodified bone marrow-derived mesenchymal stem cells transplantation promotes angiogenesis in a rat model of hindlimb ischemia. J Huazhong Univ Sci Technol Med Sci 2013; 33(4): 511-9.
-
(2013)
J Huazhong Univ Sci Technol Med Sci
, vol.33
, Issue.4
, pp. 511-519
-
-
Su, G.H.1
Sun, Y.F.2
Lu, Y.X.3
-
74
-
-
0034798898
-
Hepatocyte growth factor and macrophage-stimulating protein are upregulated during excisional wound repair in rats
-
Cowin AJ, Kallincos N, Hatzirodos N, et al. Hepatocyte growth factor and macrophage-stimulating protein are upregulated during excisional wound repair in rats. Cell Tissue Res 2001; 306(2): 239-50.
-
(2001)
Cell Tissue Res
, vol.306
, Issue.2
, pp. 239-250
-
-
Cowin, A.J.1
Kallincos, N.2
Hatzirodos, N.3
-
75
-
-
17744388788
-
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: Preclinical study for treatment of peripheral arterial disease
-
Taniyama Y, Morishita R, Aoki M, et al. Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease. Gene Ther 2001; 8(3): 181-9.
-
(2001)
Gene Ther
, vol.8
, Issue.3
, pp. 181-189
-
-
Taniyama, Y.1
Morishita, R.2
Aoki, M.3
-
76
-
-
0032979424
-
Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy
-
Morishita R, Nakamura S, Hayashi S, et al. Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy. Hypertension 1999; 33(6): 1379-84.
-
(1999)
Hypertension
, vol.33
, Issue.6
, pp. 1379-1384
-
-
Morishita, R.1
Nakamura, S.2
Hayashi, S.3
-
77
-
-
50949129278
-
Results of a doubleblind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia
-
Powell RJ, Simons M, Mendelsohn FO, et al. Results of a doubleblind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia. Circulation 2008; 118(1): 58-65.
-
(2008)
Circulation
, vol.118
, Issue.1
, pp. 58-65
-
-
Powell, R.J.1
Simons, M.2
Mendelsohn, F.O.3
-
78
-
-
78650184311
-
Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: Results of the HGF-0205 trial
-
Powell RJ, Goodney P, Mendelsohn FO, et al. Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: results of the HGF-0205 trial. J Vasc Surg 2010; 52(6): 1525-30.
-
(2010)
J Vasc Surg
, vol.52
, Issue.6
, pp. 1525-1530
-
-
Powell, R.J.1
Goodney, P.2
Mendelsohn, F.O.3
-
79
-
-
84862983062
-
Update on clinical trials evaluating the effect of biologic therapy in patients with critical limb ischemia
-
Powell RJ. Update on clinical trials evaluating the effect of biologic therapy in patients with critical limb ischemia. J Vasc Surg 2012; 56(1): 264-6.
-
(2012)
J Vasc Surg
, vol.56
, Issue.1
, pp. 264-266
-
-
Powell, R.J.1
-
80
-
-
3543025721
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease
-
Morishita R, Aoki M, Hashiya N, et al. Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Hypertension 2004; 44(2): 203-9.
-
(2004)
Hypertension
, vol.44
, Issue.2
, pp. 203-209
-
-
Morishita, R.1
Aoki, M.2
Hashiya, N.3
-
81
-
-
79952187006
-
Phase I/IIa clinical trial of therapeutic angiogenesis using hepatocyte growth factor gene transfer to treat critical limb ischemia
-
Morishita R, Makino H, Aoki M, et al. Phase I/IIa clinical trial of therapeutic angiogenesis using hepatocyte growth factor gene transfer to treat critical limb ischemia. Arterioscler Thromb Vasc Biol 2011; 31(3): 713-20.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, Issue.3
, pp. 713-720
-
-
Morishita, R.1
Makino, H.2
Aoki, M.3
-
82
-
-
84866620149
-
Long-term follow-up evaluation of results from clinical trial using hepatocyte growth factor gene to treat severe peripheral arterial disease
-
Makino H, Aoki M, Hashiya N, et al. Long-term follow-up evaluation of results from clinical trial using hepatocyte growth factor gene to treat severe peripheral arterial disease. Arterioscler Thromb Vasc Biol 2012; 32(10): 2503-9.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, Issue.10
, pp. 2503-2509
-
-
Makino, H.1
Aoki, M.2
Hashiya, N.3
-
83
-
-
77956611658
-
Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia
-
Shigematsu H, Yasuda K, Iwai T, et al. Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia. Gene Ther 2010; 17(9): 1152-61.
-
(2010)
Gene Ther
, vol.17
, Issue.9
, pp. 1152-1161
-
-
Shigematsu, H.1
Yasuda, K.2
Iwai, T.3
-
84
-
-
80051812948
-
Safety of a non-viral plasmid-encoding dual isoforms of hepatocyte growth factor in critical limb ischemia patients: A phase I study
-
Henry TD, Hirsch AT, Goldman J, et al. Safety of a non-viral plasmid-encoding dual isoforms of hepatocyte growth factor in critical limb ischemia patients: a phase I study. Gene Ther 2011; 18(8): 788-94.
-
(2011)
Gene Ther
, vol.18
, Issue.8
, pp. 788-794
-
-
Henry, T.D.1
Hirsch, A.T.2
Goldman, J.3
-
85
-
-
82455174816
-
A phase I clinical study of naked DNA expressing two isoforms of hepatocyte growth factor to treat patients with critical limb ischemia
-
Gu Y, Zhang J, Guo L, et al. A phase I clinical study of naked DNA expressing two isoforms of hepatocyte growth factor to treat patients with critical limb ischemia. J Gene Med 2011; 13(11): 602-10.
-
(2011)
J Gene Med
, vol.13
, Issue.11
, pp. 602-610
-
-
Gu, Y.1
Zhang, J.2
Guo, L.3
-
86
-
-
80054942991
-
Enhanced cardioprotective effects by coexpression of two isoforms of hepatocyte growth factor from naked plasmid DNA in a rat ischemic heart disease model
-
Hahn W, Pyun WB, Kim DS, et al. Enhanced cardioprotective effects by coexpression of two isoforms of hepatocyte growth factor from naked plasmid DNA in a rat ischemic heart disease model. J Gene Med 2011; 13(10): 549-55.
-
(2011)
J Gene Med
, vol.13
, Issue.10
, pp. 549-555
-
-
Hahn, W.1
Pyun, W.B.2
Kim, D.S.3
-
87
-
-
78650029098
-
Naked DNA expressing two isoforms of hepatocyte growth factor induces collateral artery augmentation in a rabbit model of limb ischemia
-
Pyun WB, Hahn W, Kim DS, et al. Naked DNA expressing two isoforms of hepatocyte growth factor induces collateral artery augmentation in a rabbit model of limb ischemia. Gene Ther 2010; 17(12): 1442-52.
-
(2010)
Gene Ther
, vol.17
, Issue.12
, pp. 1442-1452
-
-
Pyun, W.B.1
Hahn, W.2
Kim, D.S.3
-
89
-
-
77951698149
-
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling
-
Rey S, Semenza GL. Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling. Cardiovasc Res 2010; 86(2): 236-42.
-
(2010)
Cardiovasc Res
, vol.86
, Issue.2
, pp. 236-242
-
-
Rey, S.1
Semenza, G.L.2
-
90
-
-
0037362890
-
HIF hydroxylation and the mammalian oxygen-sensing pathway
-
Safran M, Kaelin WG Jr. HIF hydroxylation and the mammalian oxygen-sensing pathway. J Clin Invest 2003; 111(6): 779-83.
-
(2003)
J Clin Invest
, vol.111
, Issue.6
, pp. 779-783
-
-
Safran, M.1
Kaelin, W.G.2
-
91
-
-
33747621613
-
Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1
-
Semenza GL. Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. Exptl Physiol 2006; 91(5): 803-6.
-
(2006)
Exptl Physiol
, vol.91
, Issue.5
, pp. 803-806
-
-
Semenza, G.L.1
-
92
-
-
0029753008
-
Activation of hypoxiainducible transcription factor depends primarily upon redoxsensitive stabilization of its alpha subunit
-
Huang LE, Arany Z, Livingston DM, et al. Activation of hypoxiainducible transcription factor depends primarily upon redoxsensitive stabilization of its alpha subunit. J Biol Chem 1996; 271(50): 32253-9.
-
(1996)
J Biol Chem
, vol.271
, Issue.50
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
-
93
-
-
70449527373
-
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing
-
Webb JD, Coleman ML, Pugh CW. Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing. Cell Mol Life Sci 2009; 66(22): 3539-54.
-
(2009)
Cell Mol Life Sci
, vol.66
, Issue.22
, pp. 3539-3554
-
-
Webb, J.D.1
Coleman, M.L.2
Pugh, C.W.3
-
94
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003; 9(6): 677-84.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
95
-
-
43649093915
-
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
-
Kaelin WG Jr, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell 2008; 30(4): 393-402.
-
(2008)
Mol Cell
, vol.30
, Issue.4
, pp. 393-402
-
-
Kaelin, W.G.1
Ratcliffe, P.J.2
-
96
-
-
73249140173
-
Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic mice
-
Sarkar K, Fox-Talbot K, Steenbergen C, et al. Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic mice. Proc Natl Acad Sci U S A 2009; 106(44): 18769-74.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.44
, pp. 18769-18774
-
-
Sarkar, K.1
Fox-Talbot, K.2
Steenbergen, C.3
-
97
-
-
24344433563
-
Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia
-
Patel TH, Kimura H, Weiss CR, et al. Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia. Cardiovasc Res 2005; 68(1): 144-54.
-
(2005)
Cardiovasc Res
, vol.68
, Issue.1
, pp. 144-154
-
-
Patel, T.H.1
Kimura, H.2
Weiss, C.R.3
-
98
-
-
73949085704
-
Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
-
Rey S, Lee K, Wang CJ, et al. Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia. Proc Natl Acad Sci U S A 2009; 106(48): 20399-404.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.48
, pp. 20399-20404
-
-
Rey, S.1
Lee, K.2
Wang, C.J.3
-
99
-
-
37349115260
-
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia
-
Bosch-Marce M, Okuyama H, Wesley JB, et al. Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia. Circ Res 2007; 101(12): 1310-8.
-
(2007)
Circ Res
, vol.101
, Issue.12
, pp. 1310-1318
-
-
Bosch-Marce, M.1
Okuyama, H.2
Wesley, J.B.3
-
100
-
-
0034739533
-
Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor
-
Vincent KA. Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor. Circulation 2000; 102(18): 2255-61.
-
(2000)
Circulation
, vol.102
, Issue.18
, pp. 2255-2261
-
-
Vincent, K.A.1
-
101
-
-
33947727879
-
Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: Phase I doseescalation experience
-
Rajagopalan S, Olin J, Deitcher S, et al. Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: phase I doseescalation experience. Circulation 2007; 115(10): 1234-43.
-
(2007)
Circulation
, vol.115
, Issue.10
, pp. 1234-1243
-
-
Rajagopalan, S.1
Olin, J.2
Deitcher, S.3
-
102
-
-
80054960235
-
Effect of hypoxia-inducible factor-1alpha gene therapy on walking performance in patients with intermittent claudication
-
Creager MA, Olin JW, Belch JJ, et al. Effect of hypoxia-inducible factor-1alpha gene therapy on walking performance in patients with intermittent claudication. Circulation 2011; 124(16): 1765-73.
-
(2011)
Circulation
, vol.124
, Issue.16
, pp. 1765-1773
-
-
Creager, M.A.1
Olin, J.W.2
Belch, J.J.3
-
103
-
-
85047694396
-
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1
-
Zhong J, Eliceiri B, Stupack D, et al. Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. J Clin Invest 2003; 112(1): 30-41.
-
(2003)
J Clin Invest
, vol.112
, Issue.1
, pp. 30-41
-
-
Zhong, J.1
Eliceiri, B.2
Stupack, D.3
-
104
-
-
12144289916
-
Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: Its role in ischemia
-
Ho HK, Jang JJ, Kaji S, et al. Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia. Circulation 2004; 109(10): 1314-9.
-
(2004)
Circulation
, vol.109
, Issue.10
, pp. 1314-1319
-
-
Ho, H.K.1
Jang, J.J.2
Kaji, S.3
-
105
-
-
1242286566
-
Biodistribution and safety studies of hDel-1 plasmid-based gene therapy in mouse and rabbit models
-
Quezada A, Larson J, French M, et al. Biodistribution and safety studies of hDel-1 plasmid-based gene therapy in mouse and rabbit models. J Pharm Pharmacol 2004; 56(2): 177-85.
-
(2004)
J Pharm Pharmacol
, vol.56
, Issue.2
, pp. 177-185
-
-
Quezada, A.1
Larson, J.2
French, M.3
-
106
-
-
34247353352
-
Results from a phase II multicenter, double-blind placebo-controlled study of Del 1 (VLTS-589) for intermittent claudication in subjects with peripheral arterial disease
-
Grossman PM, Mendelsohn F, Henry TD, et al. Results from a phase II multicenter, double-blind placebo-controlled study of Del 1 (VLTS-589) for intermittent claudication in subjects with peripheral arterial disease. Am Heart J 2007; 153(5): 874-80.
-
(2007)
Am Heart J
, vol.153
, Issue.5
, pp. 874-880
-
-
Grossman, P.M.1
Mendelsohn, F.2
Henry, T.D.3
-
107
-
-
84879547051
-
Critical limb ischemia: Cell and molecular therapies for limb salvage
-
Davies MG. Critical limb ischemia: cell and molecular therapies for limb salvage. Methodist DeBakey Cardiovasc J 2012; 8(4): 20-7.
-
(2012)
Methodist DeBakey Cardiovasc J
, vol.8
, Issue.4
, pp. 20-27
-
-
Davies, M.G.1
-
108
-
-
70349634359
-
Meta-analysis of randomized, controlled clinical trials in angiogenesis: Gene and cell therapy in peripheral arterial disease
-
De Haro J, Acin F, Lopez-Quintana A, et al. Meta-analysis of randomized, controlled clinical trials in angiogenesis: gene and cell therapy in peripheral arterial disease. Heart Vessels 2009; 24(5): 321-8.
-
(2009)
Heart Vessels
, vol.24
, Issue.5
, pp. 321-328
-
-
De Haro, J.1
Acin, F.2
Lopez-Quintana, A.3
-
109
-
-
70350126601
-
Human studies of angiogenic gene therapy
-
Gupta R, Tongers J, Losordo DW. Human studies of angiogenic gene therapy. Circ Res 2009; 105(8): 724-36.
-
(2009)
Circ Res
, vol.105
, Issue.8
, pp. 724-736
-
-
Gupta, R.1
Tongers, J.2
Losordo, D.W.3
-
110
-
-
34347207229
-
Optimal assessment of baseline treadmill walking performance in claudication clinical trials
-
Brass EP, Jiao J, Hiatt W. Optimal assessment of baseline treadmill walking performance in claudication clinical trials. Vasc Med 2007; 12(2): 97-103.
-
(2007)
Vasc Med
, vol.12
, Issue.2
, pp. 97-103
-
-
Brass, E.P.1
Jiao, J.2
Hiatt, W.3
-
111
-
-
0037968240
-
Gene transfer as a tool to induce therapeutic vascular growth
-
Yla-Herttuala S, Alitalo K. Gene transfer as a tool to induce therapeutic vascular growth. Nat Med 2003; 9(6): 694-701.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 694-701
-
-
Yla-Herttuala, S.1
Alitalo, K.2
-
112
-
-
33847304479
-
New vectors and strategies for cardiovascular gene therapy
-
Jazwa A, Jozkowicz A, Dulak J. New vectors and strategies for cardiovascular gene therapy. Curr Gene Ther 2007; 7(1): 7-23.
-
(2007)
Curr Gene Ther
, vol.7
, Issue.1
, pp. 7-23
-
-
Jazwa, A.1
Jozkowicz, A.2
Dulak, J.3
-
114
-
-
84873148263
-
In-vivo gene delivery by sonoporation: Recent progress and prospects
-
Escoffre JM, Zeghimi A, Novell A, et al. In-vivo gene delivery by sonoporation: recent progress and prospects. Curr Gene Ther 2013; 13(1): 2-14.
-
(2013)
Curr Gene Ther
, vol.13
, Issue.1
, pp. 2-14
-
-
Escoffre, J.M.1
Zeghimi, A.2
Novell, A.3
-
115
-
-
0036918738
-
Clinical trials of gene therapy for atherosclerotic cardiovascular disease
-
Freedman SB. Clinical trials of gene therapy for atherosclerotic cardiovascular disease. Curr Opin Lipidol 2002; 13(6): 653-61.
-
(2002)
Curr Opin Lipidol
, vol.13
, Issue.6
, pp. 653-661
-
-
Freedman, S.B.1
-
116
-
-
50949121232
-
Therapeutic angiogenesis for critical limb ischemia: Microvascular therapies coming of age
-
Tongers J, Roncalli JG, Losordo DW. Therapeutic angiogenesis for critical limb ischemia: microvascular therapies coming of age. Circulation 2008; 118(1): 9-16.
-
(2008)
Circulation
, vol.118
, Issue.1
, pp. 9-16
-
-
Tongers, J.1
Roncalli, J.G.2
Losordo, D.W.3
|