Intramuscular gene transfer of fibroblast growth factor-1 using improved pCOR plasmid design stimulates collateral formation in a rabbit ischemic hindlimb model

Journal of Molecular Medicine

Volumn 84, Issue 6, 2006, Pages 491-502

  Witzenbichler, Bernhard ^a   Mahfoudi, Abderrahim ^b   Soubrier, Fabienne ^b   Le Roux, Aude ^b   Branellec, Didier ^b   Schultheiss, Heinz Peter ^a   Isner, Jeffrey M ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b SANOFI   (France)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Gene therapy; Gene transfer; Growth factors; Ischemia; Plasmid vector

Indexed keywords

BETA INTERFERON; FIBROBLAST GROWTH FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; BLOOD PRESSURE; DOPPLER FLOWMETRY; DOSE RESPONSE; EVALUATION; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; ILIAC ARTERY; LIMB ISCHEMIA; MALE; NONHUMAN; PROTEIN EXPRESSION; RABBIT; SIGNAL TRANSDUCTION; TRANSGENE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; CELLS, CULTURED; FIBROBLAST GROWTH FACTOR 1; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HINDLIMB; HUMANS; INJECTIONS, INTRAMUSCULAR; INTERFERON-BETA; ISCHEMIA; MALE; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; PLASMIDS; PROTEIN SORTING SIGNALS; RABBITS;

EID: 33744476943     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-005-0031-3     Document Type: Article

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