Update on clinical trials evaluating the effect of biologic therapy in patients with critical limb ischemia

Journal of Vascular Surgery

Volumn 56, Issue 1, 2012, Pages 264-266

  Powell, Richard J ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; IXMYELOCEL T; SCATTER FACTOR;

ALLOGENEIC STEM CELL TRANSPLANTATION; AMPUTATION; BONE MARROW BIOPSY; BONE MARROW TRANSPLANTATION; CELL THERAPY; CLINICAL TRIAL (TOPIC); CRITICAL LIMB ISCHEMIA; DISEASE FREE SURVIVAL; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; GANGRENE; HEART MUSCLE REVASCULARIZATION; HUMAN; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PATIENT MONITORING; PATIENT SAFETY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; REVIEW; STEM CELL TRANSPLANTATION; TREATMENT FAILURE;

CLINICAL TRIALS AS TOPIC; GENETIC THERAPY; HUMANS; ISCHEMIA; LOWER EXTREMITY; STEM CELL TRANSPLANTATION; WOUND HEALING;

EID: 84862983062     PISSN: 07415214     EISSN: 10976809     Source Type: Journal    
DOI: 10.1016/j.jvs.2012.03.255     Document Type: Review

References (10)

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9. R.J. Powell, A.J. Comerota, S.A. Berceli, R. Guzman, T.D. Henry, E. Tzeng Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous bone marrow-derived tissue repair cells and placebo in patients with critical limb ischemia J Vasc Surg 54 2011 1032 1041
10. Powell RJ, Marston WA, Berceli SA, Guzman R, Henry TD, Longcore AT, et al. Cellular therapy with Ixmyelocel-T to treat critical limb ischemia: the randomized, double-blind, placebo-controlled RESTORE-CLI trial [published online ahead of print March 27, 2012]. Mol Ther doi:10.1038/mt.2012.52.