-
1
-
-
37049252376
-
Structural Modifications of Histones and their Possible Role in the Regulation of RNA Synthesis
-
Allfrey VG, Mirsky AE: Structural Modifications of Histones and their Possible Role in the Regulation of RNA Synthesis. Science 1964, 144:559.
-
(1964)
Science
, vol.144
, pp. 559
-
-
Allfrey, V.G.1
Mirsky, A.E.2
-
2
-
-
78651162036
-
Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis
-
Allfrey VG, Faulkner R, Mirsky AE: Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc Natl Acad Sci USA 1964, 51:786-94.
-
(1964)
Proc Natl Acad Sci USA
, vol.51
, pp. 786-794
-
-
Allfrey, V.G.1
Faulkner, R.2
Mirsky, A.E.3
-
3
-
-
33947482638
-
The occurence of epsilon-N-methyl lysine in histones
-
Murray K: The occurence of epsilon-N-methyl lysine in histones. Biochemistry 1964, 3:10-5.
-
(1964)
Biochemistry
, vol.3
, pp. 10-15
-
-
Murray, K.1
-
4
-
-
34250785288
-
Phosphorylation of rat-thymus histone
-
Stevely WS, Stocken LA: Phosphorylation of rat-thymus histone. Biochem J 1966, 100:20C-1C.
-
(1966)
Biochem J
, vol.100
, pp. 20C-21C
-
-
Stevely, W.S.1
Stocken, L.A.2
-
5
-
-
0024041468
-
Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae
-
Han M, Kim UJ, Kayne P, Grunstein M: Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae. EMBO J 1988, 7:2221-8.
-
(1988)
EMBO J
, vol.7
, pp. 2221-2228
-
-
Han, M.1
Kim, U.J.2
Kayne, P.3
Grunstein, M.4
-
6
-
-
0025002966
-
Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae
-
Johnson LM, Kayne PS, Kahn ES, Grunstein M: Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 1990, 87:6286-90.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6286-6290
-
-
Johnson, L.M.1
Kayne, P.S.2
Kahn, E.S.3
Grunstein, M.4
-
7
-
-
0026566417
-
Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei
-
Turner BM, Birley AJ, Lavender J: Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell 1992, 69:375-84.
-
(1992)
Cell
, vol.69
, pp. 375-384
-
-
Turner, B.M.1
Birley, A.J.2
Lavender, J.3
-
8
-
-
0021715521
-
Extensive purification and characterization of chromatin-bound histone acet-yltransferase from Saccharomyces cerevisiae
-
Travis GH, Colavito-Shepanski M, Grunstein M: Extensive purification and characterization of chromatin-bound histone acet-yltransferase from Saccharomyces cerevisiae. J Biol Chem 1984, 259:14406-12.
-
(1984)
J Biol Chem
, vol.259
, pp. 14406-14412
-
-
Travis, G.H.1
Colavito-Shepanski, M.2
Grunstein, M.3
-
9
-
-
0028885077
-
Identification of a gene encoding a yeast histone H4 acetyltransferase
-
Kleff S, Andrulis ED, Anderson CW, Sternglanz R: Identification of a gene encoding a yeast histone H4 acetyltransferase. J Biol Chem 1995, 270:24674-7.
-
(1995)
J Biol Chem
, vol.270
, pp. 24674-24677
-
-
Kleff, S.1
Andrulis, E.D.2
Anderson, C.W.3
Sternglanz, R.4
-
10
-
-
0029984469
-
Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
-
Brownell JE, Zhou J, Ranalli T, Kobayashi R, Edmondson DG, Roth SY, Allis CD: Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 1996, 84:843-51.
-
(1996)
Cell
, vol.84
, pp. 843-851
-
-
Brownell, J.E.1
Zhou, J.2
Ranalli, T.3
Kobayashi, R.4
Edmondson, D.G.5
Roth, S.Y.6
Allis, C.D.7
-
11
-
-
0029932598
-
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
-
Taunton J, Hassig CA, Schreiber SL: A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 1996, 272:408-11.
-
(1996)
Science
, vol.272
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
12
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
Rea S, Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD, Jenuwein T: Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 2000, 406:593-9.
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
Eisenhaber, F.2
O'Carroll, D.3
Strahl, B.D.4
Sun, Z.W.5
Schmid, M.6
Opravil, S.7
Mechtler, K.8
Ponting, C.P.9
Allis, C.D.10
Jenuwein, T.11
-
13
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y: Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004, 119:941-53.
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
14
-
-
0024477454
-
Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage
-
Turner BM: Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage. Exp Cell Res 1989, 182:206-14.
-
(1989)
Exp Cell Res
, vol.182
, pp. 206-214
-
-
Turner, B.M.1
-
15
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD: The language of covalent histone modifications. Nature 2000, 403:41-5.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
16
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD: Translating the histone code. Science 2001, 293:1074-80.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
17
-
-
0033848849
-
Histone acetylation and an epigenetic code
-
Turner BM: Histone acetylation and an epigenetic code. Bioessays 2000, 22:836-45.
-
(2000)
Bioessays
, vol.22
, pp. 836-845
-
-
Turner, B.M.1
-
18
-
-
80054998839
-
Chemical approaches to understand the language of histone modifications
-
Dhall A, Chatterjee C: Chemical approaches to understand the language of histone modifications. ACS Chem Biol 2011, 6:987-99.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 987-999
-
-
Dhall, A.1
Chatterjee, C.2
-
19
-
-
84887057701
-
The promise and failures of epigenetic therapies for cancer treatment
-
Bojang P, Ramos KS: The promise and failures of epigenetic therapies for cancer treatment. Cancer Treat Rev 2014, 40:153-69.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 153-169
-
-
Bojang, P.1
Ramos, K.S.2
-
20
-
-
35848961668
-
How chromatin-binding modules interpret histone modifications: Lessons from professional pocket pickers
-
Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ: How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol 2007, 14:1025-40.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1025-1040
-
-
Taverna, S.D.1
Li, H.2
Ruthenburg, A.J.3
Allis, C.D.4
Patel, D.J.5
-
21
-
-
79952536146
-
The double face of the histone variant H3.3
-
Szenker E, Ray-Gallet D, Almouzni G: The double face of the histone variant H3.3. Cell Res 2011, 21:421-34.
-
(2011)
Cell Res
, vol.21
, pp. 421-434
-
-
Szenker, E.1
Ray-Gallet, D.2
Almouzni, G.3
-
22
-
-
84886298616
-
Developmental roles of histone H3 variants and their chaperones
-
Filipescu D, Szenker E, Almouzni G: Developmental roles of histone H3 variants and their chaperones. Trends Genet 2013, 29:630-40.
-
(2013)
Trends Genet
, vol.29
, pp. 630-640
-
-
Filipescu, D.1
Szenker, E.2
Almouzni, G.3
-
23
-
-
79952534189
-
Regulation of chromatin by histone modifications
-
Bannister AJ, Kouzarides T: Regulation of chromatin by histone modifications. Cell Res 2011, 21:381-95.
-
(2011)
Cell Res
, vol.21
, pp. 381-395
-
-
Bannister, A.J.1
Kouzarides, T.2
-
25
-
-
79959967699
-
Antibody recognition of histone posttranslational modifications: Emerging issues and future prospects
-
Fuchs SM, Strahl BD: Antibody recognition of histone posttranslational modifications: emerging issues and future prospects. Epigenomics 2011, 3:247-9.
-
(2011)
Epigenomics
, vol.3
, pp. 247-249
-
-
Fuchs, S.M.1
Strahl, B.D.2
-
26
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, Roh T, Schones DE, Wang Z, Wei G, Chepelev I, Zhao K: High-resolution profiling of histone methylations in the human genome. Cell 2007, 129:823-37.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
27
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim T, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander ES, Bernstein BE: Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007, 448:553-60.
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
Alvarez, P.7
Brockman, W.8
Kim, T.9
Koche, R.P.10
Lee, W.11
Mendenhall, E.12
O'Donovan, A.13
Presser, A.14
Russ, C.15
Xie, X.16
Meissner, A.17
Wernig, M.18
Jaenisch, R.19
Nusbaum, C.20
Lander, E.S.21
Bernstein, B.E.22
more..
-
28
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
Johnson DS, Mortazavi A, Myers RM, Wold B: Genome-wide mapping of in vivo protein-DNA interactions. Science 2007, 316:1497-502.
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
Wold, B.4
-
29
-
-
84861883921
-
Sequential ChIP-bisulfite sequencing enables direct genomescale investigation of chromatin and DNA methylation crosstalk
-
Brinkman AB, Gu H, Bartels, Stefanie J J, Zhang Y, Matarese F, Simmer F, Marks H, Bock C, Gnirke A, Meissner A, Stunnenberg HG: Sequential ChIP-bisulfite sequencing enables direct genomescale investigation of chromatin and DNA methylation crosstalk. Genome Res 2012, 22:1128-38.
-
(2012)
Genome Res
, vol.22
, pp. 1128-1138
-
-
Brinkman, A.B.1
Gu, H.2
Bartels3
Stefanie, J.J.4
Zhang, Y.5
Matarese, F.6
Simmer, F.7
Marks, H.8
Bock, C.9
Gnirke, A.10
Meissner, A.11
Stunnenberg, H.G.12
-
30
-
-
84864308665
-
ChAP-MS: A method for identification of proteins and histone posttranslational modifications at a single genomic locus
-
Byrum SD, Raman A, Taverna SD, Tackett AJ: ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus. Cell Rep 2012, 2:198-205.
-
(2012)
Cell Rep
, vol.2
, pp. 198-205
-
-
Byrum, S.D.1
Raman, A.2
Taverna, S.D.3
Tackett, A.J.4
-
31
-
-
84895455197
-
Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components
-
Alabert C, Bukowski-Wills J, Lee S, Kustatscher G, Nakamura K, de Lima Alves, Flavia, Menard P, Mejlvang J, Rappsilber J, Groth A: Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components. Nat Cell Biol 2014, 16:281-93.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 281-293
-
-
Alabert, C.1
Bukowski-Wills, J.2
Lee, S.3
Kustatscher, G.4
Nakamura, K.5
De Lima Alves, F.6
Menard, P.7
Mejlvang, J.8
Rappsilber, J.9
Groth, A.10
-
32
-
-
84887081781
-
Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry
-
Sirbu BM, McDonald WH, Dungrawala H, Badu-Nkansah A, Kavanaugh GM, Chen Y, Tabb DL, Cortez D: Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry. J Biol Chem 2013, 288:31458-67.
-
(2013)
J Biol Chem
, vol.288
, pp. 31458-31467
-
-
Sirbu, B.M.1
McDonald, W.H.2
Dungrawala, H.3
Badu-Nkansah, A.4
Kavanaugh, G.M.5
Chen, Y.6
Tabb, D.L.7
Cortez, D.8
-
33
-
-
84890048526
-
Targeted DNA demethylation and activation of endogenous genes using programmable TALETET1 fusion proteins
-
Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK: Targeted DNA demethylation and activation of endogenous genes using programmable TALETET1 fusion proteins. Nat Biotechnol 2013, 31:1137-42.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1137-1142
-
-
Maeder, M.L.1
Angstman, J.F.2
Richardson, M.E.3
Linder, S.J.4
Cascio, V.M.5
Tsai, S.Q.6
Ho, Q.H.7
Sander, J.D.8
Reyon, D.9
Bernstein, B.E.10
Costello, J.F.11
Wilkinson, M.F.12
Joung, J.K.13
-
34
-
-
84886084801
-
Locus-specific editing of histone modifications at endogenous enhancers
-
Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, Bernstein BE: Locus-specific editing of histone modifications at endogenous enhancers. Nat Biotechnol 2013, 31:1133-6.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1133-1136
-
-
Mendenhall, E.M.1
Williamson, K.E.2
Reyon, D.3
Zou, J.Y.4
Ram, O.5
Joung, J.K.6
Bernstein, B.E.7
-
35
-
-
84882976110
-
Optical control of mammalian endogenous transcription and epigenetic states
-
Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Le Cong, Platt RJ, Scott DA, Church GM, Zhang F: Optical control of mammalian endogenous transcription and epigenetic states. Nature 2013, 500:472-6.
-
(2013)
Nature
, vol.500
, pp. 472-476
-
-
Konermann, S.1
Brigham, M.D.2
Trevino, A.E.3
Hsu, P.D.4
Heidenreich, M.5
Cong, L.6
Platt, R.J.7
Scott, D.A.8
Church, G.M.9
Zhang, F.10
-
36
-
-
79151470871
-
Influence of combinatorial histone modifications on antibody and effector protein recognition
-
Fuchs SM, Krajewski K, Baker RW, Miller VL, Strahl BD: Influence of combinatorial histone modifications on antibody and effector protein recognition. Curr Biol 2011, 21:53-8.
-
(2011)
Curr Biol
, vol.21
, pp. 53-58
-
-
Fuchs, S.M.1
Krajewski, K.2
Baker, R.W.3
Miller, V.L.4
Strahl, B.D.5
-
37
-
-
33847386172
-
The site-specific installation of methyl-lysine analogs into recombinant histones
-
Simon MD, Chu F, Racki LR, de la Cruz, Cecile C, Burlingame AL, Panning B, Narlikar GJ, Shokat KM: The site-specific installation of methyl-lysine analogs into recombinant histones. Cell 2007, 128:1003-12.
-
(2007)
Cell
, vol.128
, pp. 1003-1012
-
-
Simon, M.D.1
Chu, F.2
Racki, L.R.3
De La Cruz4
Cecile, C.5
Burlingame, A.L.6
Panning, B.7
Narlikar, G.J.8
Shokat, K.M.9
-
38
-
-
70349765673
-
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation
-
Neumann H, Hancock SM, Buning R, Routh A, Chapman L, Somers J, Owen-Hughes T, van Noort J, Rhodes D, Chin JW: A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation. Mol Cell 2009, 36:153-63.
-
(2009)
Mol Cell
, vol.36
, pp. 153-163
-
-
Neumann, H.1
Hancock, S.M.2
Buning, R.3
Routh, A.4
Chapman, L.5
Somers, J.6
Owen-Hughes, T.7
Van Noort, J.8
Rhodes, D.9
Chin, J.W.10
-
39
-
-
77958073850
-
Development of stable phosphohistidine analogues
-
Kee J, Villani B, Carpenter LR, Muir TW: Development of stable phosphohistidine analogues. J Am Chem Soc 2010, 132:14327-9.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 14327-14329
-
-
Kee, J.1
Villani, B.2
Carpenter, L.R.3
Muir, T.W.4
-
40
-
-
77949874828
-
Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation
-
Chatterjee C, McGinty RK, Fierz B, Muir TW: Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation. Nat Chem Biol 2010, 6:267-9.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 267-269
-
-
Chatterjee, C.1
McGinty, R.K.2
Fierz, B.3
Muir, T.W.4
-
41
-
-
84863808085
-
Peptide microarrays to interrogate the "histone code"
-
Rothbart SB, Krajewski K, Strahl BD, Fuchs SM: Peptide microarrays to interrogate the "histone code". Meth Enzymol 2012, 512:107-35.
-
(2012)
Meth Enzymol
, vol.512
, pp. 107-135
-
-
Rothbart, S.B.1
Krajewski, K.2
Strahl, B.D.3
Fuchs, S.M.4
-
42
-
-
79151476637
-
Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays
-
Bock I, Dhayalan A, Kudithipudi S, Brandt O, Rathert P, Jeltsch A: Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays. Epigenetics 2011, 6:256-63.
-
(2011)
Epigenetics
, vol.6
, pp. 256-263
-
-
Bock, I.1
Dhayalan, A.2
Kudithipudi, S.3
Brandt, O.4
Rathert, P.5
Jeltsch, A.6
-
43
-
-
78650985680
-
An assessment of histone-modification antibody quality
-
Egelhofer TA, Minoda A, Klugman S, Lee K, Kolasinska-Zwierz P, Alekseyenko AA, Cheung M, Day DS, Gadel S, Gorchakov AA, Gu T, Kharchenko PV, Kuan S, Latorre I, Linder-Basso D, Luu Y, Ngo Q, Perry M, Rechtsteiner A, Riddle NC, Schwartz YB, Shanower GA, Vielle A, Ahringer J, Elgin, Sarah C R, Kuroda MI, Pirrotta V, Ren B, Strome S, Park PJ, et al.: An assessment of histone-modification antibody quality. Nat Struct Mol Biol 2011, 18:91-3.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 91-93
-
-
Egelhofer, T.A.1
Minoda, A.2
Klugman, S.3
Lee, K.4
Kolasinska-Zwierz, P.5
Alekseyenko, A.A.6
Cheung, M.7
Day, D.S.8
Gadel, S.9
Gorchakov, A.A.10
Gu, T.11
Kharchenko, P.V.12
Kuan, S.13
Latorre, I.14
Linder-Basso, D.15
Luu, Y.16
Ngo, Q.17
Perry, M.18
Rechtsteiner, A.19
Riddle, N.C.20
Schwartz, Y.B.21
Shanower, G.A.22
Vielle, A.23
Ahringer, J.24
Elgin Sarah, C.R.25
Kuroda, M.I.26
Pirrotta, V.27
Ren, B.28
Strome, S.29
Park, P.J.30
more..
-
44
-
-
77956916411
-
Bähr K, Mrksich M: Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity
-
Gurard-Levin ZA, Kilian KA, Kim J, Bähr K, Mrksich M: Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity. ACS Chem Biol 2010, 5:863-73.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 863-873
-
-
Gurard-Levin, Z.A.1
Kilian, K.A.2
Kim, J.3
-
45
-
-
77952884316
-
An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases
-
Ibáñez G, McBean JL, Astudillo YM, Luo M: An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases. Anal Biochem 2010, 401:203-10.
-
(2010)
Anal Biochem
, vol.401
, pp. 203-210
-
-
Ibáñez, G.1
McBean, J.L.2
Astudillo, Y.M.3
Luo, M.4
-
46
-
-
48649109948
-
A combinatorial H4 tail library for exploring the histone code
-
Garske AL, Craciun G, Denu JM: A combinatorial H4 tail library for exploring the histone code. Biochemistry 2008, 47:8094-102.
-
(2008)
Biochemistry
, vol.47
, pp. 8094-8102
-
-
Garske, A.L.1
Craciun, G.2
Denu, J.M.3
-
47
-
-
78449259404
-
Method for the synthesis of mono-ADP-ribose conjugated peptides
-
Moyle PM, Muir TW: Method for the synthesis of mono-ADP-ribose conjugated peptides. J Am Chem Soc 2010, 132:15878-80.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 15878-15880
-
-
Moyle, P.M.1
Muir, T.W.2
-
48
-
-
44949231404
-
The activity of HDAC8 depends on local and distal sequences of its peptide substrates
-
Gurard-Levin ZA, Mrksich M: The activity of HDAC8 depends on local and distal sequences of its peptide substrates. Biochemistry 2008, 47:6242-50.
-
(2008)
Biochemistry
, vol.47
, pp. 6242-6250
-
-
Gurard-Levin, Z.A.1
Mrksich, M.2
-
49
-
-
20444431507
-
Substrate-specific activation of sirtuins by resveratrol
-
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK: Substrate-specific activation of sirtuins by resveratrol. J Biol Chem 2005, 280:17038-45.
-
(2005)
J Biol Chem
, vol.280
, pp. 17038-17045
-
-
Kaeberlein, M.1
McDonagh, T.2
Heltweg, B.3
Hixon, J.4
Westman, E.A.5
Caldwell, S.D.6
Napper, A.7
Curtis, R.8
DiStefano, P.S.9
Fields, S.10
Bedalov, A.11
Kennedy, B.K.12
-
50
-
-
79960233029
-
High-throughput screening of small molecule libraries using SAMDI mass spectrometry
-
Gurard-Levin ZA, Scholle MD, Eisenberg AH, Mrksich M: High-throughput screening of small molecule libraries using SAMDI mass spectrometry. ACS Comb Sci 2011, 13:347-50.
-
(2011)
ACS Comb Sci
, vol.13
, pp. 347-350
-
-
Gurard-Levin, Z.A.1
Scholle, M.D.2
Eisenberg, A.H.3
Mrksich, M.4
-
51
-
-
80054085409
-
Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay
-
Plant M, Dineen T, Cheng A, Long AM, Chen H, Morgenstern KA: Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay. Anal Biochem 2011, 419:217-27.
-
(2011)
Anal Biochem
, vol.419
, pp. 217-227
-
-
Plant, M.1
Dineen, T.2
Cheng, A.3
Long, A.M.4
Chen, H.5
Morgenstern, K.A.6
-
52
-
-
0036583926
-
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
-
Ong S, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, Mann M: Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 2002, 1:376-86.
-
(2002)
Mol Cell Proteomics
, vol.1
, pp. 376-386
-
-
Ong, S.1
Blagoev, B.2
Kratchmarova, I.3
Kristensen, D.B.4
Steen, H.5
Pandey, A.6
Mann, M.7
-
53
-
-
34247110340
-
Mass spectrometry-based strategies for characterization of histones and their post-translational modifications
-
Su X, Ren C, Freitas MA: Mass spectrometry-based strategies for characterization of histones and their post-translational modifications. Expert Rev Proteomics 2007, 4:211-25.
-
(2007)
Expert Rev Proteomics
, vol.4
, pp. 211-225
-
-
Su, X.1
Ren, C.2
Freitas, M.A.3
-
54
-
-
84892785163
-
Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification
-
Tessarz P, Santos-Rosa H, Robson SC, Sylvestersen KB, Nelson CJ, Nielsen ML, Kouzarides T: Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification. Nature 2014, 505:564-8.
-
(2014)
Nature
, vol.505
, pp. 564-568
-
-
Tessarz, P.1
Santos-Rosa, H.2
Robson, S.C.3
Sylvestersen, K.B.4
Nelson, C.J.5
Nielsen, M.L.6
Kouzarides, T.7
-
55
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S, Jin F, Yang JS, Montellier E, Buchou T, Cheng Z, Rousseaux S, Rajagopal N, Lu Z, Ye Z, Zhu Q, Wysocka J, Ye Y, Khochbin S, Ren B, Zhao Y: Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 2011, 146:1016-28.
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
Jin, F.4
Yang, J.S.5
Montellier, E.6
Buchou, T.7
Cheng, Z.8
Rousseaux, S.9
Rajagopal, N.10
Lu, Z.11
Ye, Z.12
Zhu, Q.13
Wysocka, J.14
Ye, Y.15
Khochbin, S.16
Ren, B.17
Zhao, Y.18
-
56
-
-
79957537645
-
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions
-
Ruthenburg AJ, Li H, Milne TA, Dewell S, McGinty RK, Yuen M, Ueberheide B, Dou Y, Muir TW, Patel DJ, Allis CD: Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell 2011, 145:692-706.
-
(2011)
Cell
, vol.145
, pp. 692-706
-
-
Ruthenburg, A.J.1
Li, H.2
Milne, T.A.3
Dewell, S.4
McGinty, R.K.5
Yuen, M.6
Ueberheide, B.7
Dou, Y.8
Muir, T.W.9
Patel, D.J.10
Allis, C.D.11
-
57
-
-
79956326274
-
Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas
-
Xu C, Cole PA, Meyers DJ, Kormish J, Dent S, Zaret KS: Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas. Science 2011, 332:963-6.
-
(2011)
Science
, vol.332
, pp. 963-966
-
-
Xu, C.1
Cole, P.A.2
Meyers, D.J.3
Kormish, J.4
Dent, S.5
Zaret, K.S.6
-
58
-
-
80455131094
-
Quantitative proteomic approaches to studying histone modifications
-
Zee BM, Young NL, Garcia BA: Quantitative proteomic approaches to studying histone modifications. Curr Chem Genomics 2011, 5:106-14.
-
(2011)
Curr Chem Genomics
, vol.5
, pp. 106-114
-
-
Zee, B.M.1
Young, N.L.2
Garcia, B.A.3
-
59
-
-
77951794785
-
Mass spectrometric analysis of histone variants and post-translational modifications
-
Garcia BA: Mass spectrometric analysis of histone variants and post-translational modifications. Front Biosci (Schol Ed) 2009, 1:142-53.
-
(2009)
Front Biosci (Schol Ed)
, vol.1
, pp. 142-153
-
-
Garcia, B.A.1
-
60
-
-
78751516164
-
Quantitative proteomics for epigenetics
-
Eberl HC, Mann M, Vermeulen M: Quantitative proteomics for epigenetics. Chembiochem 2011, 12:224-34.
-
(2011)
Chembiochem
, vol.12
, pp. 224-234
-
-
Eberl, H.C.1
Mann, M.2
Vermeulen, M.3
-
61
-
-
80055088176
-
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling
-
Hayashi-Takanaka Y, Yamagata K, Wakayama T, Stasevich TJ, Kainuma T, Tsurimoto T, Tachibana M, Shinkai Y, Kurumizaka H, Nozaki N, Kimura H: Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. Nucleic Acids Res 2011, 39:6475-88.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 6475-6488
-
-
Hayashi-Takanaka, Y.1
Yamagata, K.2
Wakayama, T.3
Stasevich, T.J.4
Kainuma, T.5
Tsurimoto, T.6
Tachibana, M.7
Shinkai, Y.8
Kurumizaka, H.9
Nozaki, N.10
Kimura, H.11
-
62
-
-
84877318097
-
Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells
-
Murphy PJ, Cipriany BR, Wallin CB, Ju CY, Szeto K, Hagarman JA, Benitez JJ, Craighead HG, Soloway PD: Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells. Proc Natl Acad Sci USA 2013, 110:7772-7.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 7772-7777
-
-
Murphy, P.J.1
Cipriany, B.R.2
Wallin, C.B.3
Ju, C.Y.4
Szeto, K.5
Hagarman, J.A.6
Benitez, J.J.7
Craighead, H.G.8
Soloway, P.D.9
-
63
-
-
84873383204
-
Detection of histone modifications at specific gene loci in single cells in histological sections
-
Gomez D, Shankman LS, Nguyen AT, Owens GK: Detection of histone modifications at specific gene loci in single cells in histological sections. Nat Methods 2013, 10:171-7.
-
(2013)
Nat Methods
, vol.10
, pp. 171-177
-
-
Gomez, D.1
Shankman, L.S.2
Nguyen, A.T.3
Owens, G.K.4
-
64
-
-
77953578193
-
Söderberg O: Proximity ligation assays: a recent addition to the proteomics toolbox
-
Weibrecht I, Leuchowius K, Clausson C, Conze T, Jarvius M, Howell WM, Kamali-Moghaddam M, Söderberg O: Proximity ligation assays: a recent addition to the proteomics toolbox. Expert Rev Proteomics 2010, 7:401-9.
-
(2010)
Expert Rev Proteomics
, vol.7
, pp. 401-409
-
-
Weibrecht, I.1
Leuchowius, K.2
Clausson, C.3
Conze, T.4
Jarvius, M.5
Howell, W.M.6
Kamali-Moghaddam, M.7
-
65
-
-
0742304304
-
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis
-
Tagami H, Ray-Gallet D, Almouzni G, Nakatani Y: Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell 2004, 116:51-61.
-
(2004)
Cell
, vol.116
, pp. 51-61
-
-
Tagami, H.1
Ray-Gallet, D.2
Almouzni, G.3
Nakatani, Y.4
-
66
-
-
78549235007
-
The program for processing newly synthesized histones H3.1 and H4
-
Campos EI, Fillingham J, Li G, Zheng H, Voigt P, Kuo WW, Seepany H, Gao Z, Day LA, Greenblatt JF, Reinberg D: The program for processing newly synthesized histones H3.1 and H4. Nat Struct Mol Biol 2010, 17:1343-51.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1343-1351
-
-
Campos, E.I.1
Fillingham, J.2
Li, G.3
Zheng, H.4
Voigt, P.5
Kuo, W.W.6
Seepany, H.7
Gao, Z.8
Day, L.A.9
Greenblatt, J.F.10
Reinberg, D.11
-
67
-
-
79955945767
-
Sequential establishment of marks on soluble histones H3 and H4
-
Alvarez F, Muñoz F, Schilcher P, Imhof A, Almouzni G, Loyola A: Sequential establishment of marks on soluble histones H3 and H4. J Biol Chem 2011, 286:17714-21.
-
(2011)
J Biol Chem
, vol.286
, pp. 17714-17721
-
-
Alvarez, F.1
Muñoz, F.2
Schilcher, P.3
Imhof, A.4
Almouzni, G.5
Loyola, A.6
-
68
-
-
33749657892
-
PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state
-
Loyola A, Bonaldi T, Roche D, Imhof A, Almouzni G: PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state. Mol Cell 2006, 24:309-16.
-
(2006)
Mol Cell
, vol.24
, pp. 309-316
-
-
Loyola, A.1
Bonaldi, T.2
Roche, D.3
Imhof, A.4
Almouzni, G.5
-
69
-
-
0025716314
-
DNA methylation and epigenetic inheritance
-
Holliday R: DNA methylation and epigenetic inheritance. Philos Trans R Soc Lond B, Biol Sci 1990, 326:329-38.
-
(1990)
Philos Trans R Soc Lond B, Biol Sci
, vol.326
, pp. 329-338
-
-
Holliday, R.1
-
70
-
-
77649268110
-
Replication stress interferes with histone recycling and predeposition marking of new histones
-
Jasencakova Z, Scharf, Annette N D, Ask K, Corpet A, Imhof A, Almouzni G, Groth A: Replication stress interferes with histone recycling and predeposition marking of new histones. Mol Cell 2010, 37:736-43.
-
(2010)
Mol Cell
, vol.37
, pp. 736-743
-
-
Jasencakova, Z.1
Scharf2
Annette, N.D.3
Ask, K.4
Corpet, A.5
Imhof, A.6
Almouzni, G.7
Groth, A.8
-
71
-
-
33947274529
-
Propagation of centromeric chromatin requires exit from mitosis
-
Jansen, Lars E T, Black BE, Foltz DR, Cleveland DW: Propagation of centromeric chromatin requires exit from mitosis. J Cell Biol 2007, 176:795-805.
-
(2007)
J Cell Biol
, vol.176
, pp. 795-805
-
-
Jansen, L.E.T.1
Black, B.E.2
Foltz, D.R.3
Cleveland, D.W.4
-
72
-
-
58149522909
-
Making copies of chromatin: The challenge of nucleosomal organization and epigenetic information
-
Corpet A, Almouzni G: Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information. Trends Cell Biol 2009, 19:29-41.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 29-41
-
-
Corpet, A.1
Almouzni, G.2
-
73
-
-
84857430552
-
Chromatin replication and epigenome maintenance
-
Alabert C, Groth A: Chromatin replication and epigenome maintenance. Nat Rev Mol Cell Biol 2012, 13:153-67.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 153-167
-
-
Alabert, C.1
Groth, A.2
-
74
-
-
84902203517
-
Histone chaperones: Assisting histone traffic and nucleosome dynamics
-
Gurard-Levin ZA, Quivy J, Almouzni G: Histone chaperones: assisting histone traffic and nucleosome dynamics. Annu Rev Biochem 2014, 83:487-517.
-
(2014)
Annu Rev Biochem
, vol.83
, pp. 487-517
-
-
Gurard-Levin, Z.A.1
Quivy, J.2
Almouzni, G.3
-
75
-
-
37549049820
-
Regulation of replication fork progression through histone supply and demand
-
Groth A, Corpet A, Cook, Adam J L, Roche D, Bartek J, Lukas J, Almouzni G: Regulation of replication fork progression through histone supply and demand. Science 2007, 318:1928-31.
-
(2007)
Science
, vol.318
, pp. 1928-1931
-
-
Groth, A.1
Corpet, A.2
Cook Adam, J.L.3
Roche, D.4
Bartek, J.5
Lukas, J.6
Almouzni, G.7
-
76
-
-
84255162049
-
Dynamics of histone H3 deposition in vivo reveal a nucleosome gap-filling mechanism for H3.3 to maintain chromatin integrity
-
Ray-Gallet D, Woolfe A, Vassias I, Pellentz C, Lacoste N, Puri A, Schultz DC, Pchelintsev NA, Adams PD, Jansen, Lars E T, Almouzni G: Dynamics of histone H3 deposition in vivo reveal a nucleosome gap-filling mechanism for H3.3 to maintain chromatin integrity. Mol Cell 2011, 44:928-41.
-
(2011)
Mol Cell
, vol.44
, pp. 928-941
-
-
Ray-Gallet, D.1
Woolfe, A.2
Vassias, I.3
Pellentz, C.4
Lacoste, N.5
Puri, A.6
Schultz, D.C.7
Pchelintsev, N.A.8
Adams, P.D.9
Jansen, L.E.T.10
Almouzni, G.11
-
77
-
-
84867009687
-
Asymmetrically modified nucleosomes
-
Voigt P, LeRoy G, Drury WJ, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D: Asymmetrically modified nucleosomes. Cell 2012, 151:181-93.
-
(2012)
Cell
, vol.151
, pp. 181-193
-
-
Voigt, P.1
LeRoy, G.2
Drury, W.J.3
Zee, B.M.4
Son, J.5
Beck, D.B.6
Young, N.L.7
Garcia, B.A.8
Reinberg, D.9
-
78
-
-
84894244513
-
Mislocalization of the centromeric histone variant CenH3/CENP-A in human cells depends on the chaperone DAXX
-
Lacoste N, Woolfe A, Tachiwana H, Garea AV, Barth T, Cantaloube S, Kurumizaka H, Imhof A, Almouzni G: Mislocalization of the centromeric histone variant CenH3/CENP-A in human cells depends on the chaperone DAXX. Mol Cell 2014, 53:631-44.
-
(2014)
Mol Cell
, vol.53
, pp. 631-644
-
-
Lacoste, N.1
Woolfe, A.2
Tachiwana, H.3
Garea, A.V.4
Barth, T.5
Cantaloube, S.6
Kurumizaka, H.7
Imhof, A.8
Almouzni, G.9
-
79
-
-
84884889017
-
Transcription recovery after DNA damage requires chromatin priming by the H3.3 histone chaperone HIRA
-
Adam S, Polo SE, Almouzni G: Transcription recovery after DNA damage requires chromatin priming by the H3.3 histone chaperone HIRA. Cell 2013, 155:94-106.
-
(2013)
Cell
, vol.155
, pp. 94-106
-
-
Adam, S.1
Polo, S.E.2
Almouzni, G.3
-
80
-
-
84866497062
-
Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes
-
Venkatesh S, Smolle M, Li H, Gogol MM, Saint M, Kumar S, Natarajan K, Workman JL: Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes. Nature 2012, 489:452-5.
-
(2012)
Nature
, vol.489
, pp. 452-455
-
-
Venkatesh, S.1
Smolle, M.2
Li, H.3
Gogol, M.M.4
Saint, M.5
Kumar, S.6
Natarajan, K.7
Workman, J.L.8
-
81
-
-
84906725999
-
Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication
-
Petruk S, Black KL, Kovermann SK, Brock HW, Mazo A: Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication. Nat Commun 2013, 4:2841.
-
(2013)
Nat Commun
, vol.4
, pp. 2841
-
-
Petruk, S.1
Black, K.L.2
Kovermann, S.K.3
Brock, H.W.4
Mazo, A.5
-
82
-
-
1842733449
-
HP1 and the dynamics of heterochromatin maintenance
-
Maison C, Almouzni G: HP1 and the dynamics of heterochromatin maintenance. Nat Rev Mol Cell Biol 2004, 5:296-304.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 296-304
-
-
Maison, C.1
Almouzni, G.2
-
83
-
-
70349952171
-
Role of the polycomb protein EED in the propagation of repressive histone marks
-
Margueron R, Justin N, Ohno K, Sharpe ML, Son J, Drury WJ, Voigt P, Martin SR, Taylor WR, Marco V de, Pirrotta V, Reinberg D, Gamblin SJ: Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 2009, 461:762-7.
-
(2009)
Nature
, vol.461
, pp. 762-767
-
-
Margueron, R.1
Justin, N.2
Ohno, K.3
Sharpe, M.L.4
Son, J.5
Drury, W.J.6
Voigt, P.7
Martin, S.R.8
Taylor, W.R.9
Marco, V.10
De Pirrotta, V.11
Reinberg, D.12
Gamblin, S.J.13
-
84
-
-
78649698079
-
Global turnover of histone post-translational modifications and variants in human cells
-
Zee BM, Levin RS, Dimaggio PA, Garcia BA: Global turnover of histone post-translational modifications and variants in human cells. Epigenetics Chromatin 2010, 3:22.
-
(2010)
Epigenetics Chromatin
, vol.3
, pp. 22
-
-
Zee, B.M.1
Levin, R.S.2
Dimaggio, P.A.3
Garcia, B.A.4
-
85
-
-
78049246250
-
Fast signals and slow marks: The dynamics of histone modifications
-
Barth TK, Imhof A: Fast signals and slow marks: the dynamics of histone modifications. Trends Biochem Sci 2010, 35:618-26.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 618-626
-
-
Barth, T.K.1
Imhof, A.2
-
86
-
-
84865681429
-
TrxG and PcG proteins but not methylated histones remain associated with DNA through replication
-
Petruk S, Sedkov Y, Johnston DM, Hodgson JW, Black KL, Kovermann SK, Beck S, Canaani E, Brock HW, Mazo A: TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell 2012, 150:922-33.
-
(2012)
Cell
, vol.150
, pp. 922-933
-
-
Petruk, S.1
Sedkov, Y.2
Johnston, D.M.3
Hodgson, J.W.4
Black, K.L.5
Kovermann, S.K.6
Beck, S.7
Canaani, E.8
Brock, H.W.9
Mazo, A.10
-
87
-
-
84896033884
-
Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication
-
Jacob Y, Bergamin E, Donoghue, Mark T A, Mongeon V, LeBlanc C, Voigt P, Underwood CJ, Brunzelle JS, Michaels SD, Reinberg D, Couture J, Martienssen RA: Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication. Science 2014, 343:1249-53.
-
(2014)
Science
, vol.343
, pp. 1249-1253
-
-
Jacob, Y.1
Bergamin, E.2
Donoghue3
Mark, T.A.4
Mongeon, V.5
LeBlanc, C.6
Voigt, P.7
Underwood, C.J.8
Brunzelle, J.S.9
Michaels, S.D.10
Reinberg, D.11
Couture, J.12
Martienssen, R.A.13
-
88
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J, Korshunov A, Liu X, Jones, David T W, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DK, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jäger N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Frühwald MC, et al.: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012, 482:226-31.
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.3
Jones4
David, T.W.5
Pfaff, E.6
Jacob, K.7
Sturm, D.8
Fontebasso, A.M.9
Quang, D.K.10
Tönjes, M.11
Hovestadt, V.12
Albrecht, S.13
Kool, M.14
Nantel, A.15
Konermann, C.16
Lindroth, A.17
Jäger, N.18
Rausch, T.19
Ryzhova, M.20
Korbel, J.O.21
Hielscher, T.22
Hauser, P.23
Garami, M.24
Klekner, A.25
Bognar, L.26
Ebinger, M.27
Schuhmann, M.U.28
Scheurlen, W.29
Pekrun, A.30
Frühwald, M.C.31
more..
-
89
-
-
84899539535
-
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
-
Fontebasso AM, Papillon-Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset P, Bechet D, Faury D, Jay N de, Ramkissoon LA, Corcoran A, Jones, David T W, Sturm D, Johann P, Tomita T, Goldman S, Nagib M, Bendel A, Goumnerova L, Bowers DC, Leonard JR, Rubin JB, Alden T, Browd S, Geyer JR, Leary S, Jallo G, Cohen K, Gupta N, Prados MD, et al.: Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. Nat Genet 2014, 46:462-6.
-
(2014)
Nat Genet
, vol.46
, pp. 462-466
-
-
Fontebasso, A.M.1
Papillon-Cavanagh, S.2
Schwartzentruber, J.3
Nikbakht, H.4
Gerges, N.5
Fiset, P.6
Bechet, D.7
Faury, D.8
Jay, N.9
De Ramkissoon, L.A.10
Corcoran, A.11
Jones, D.T.W.12
Sturm, D.13
Johann, P.14
Tomita, T.15
Goldman, S.16
Nagib, M.17
Bendel, A.18
Goumnerova, L.19
Bowers, D.C.20
Leonard, J.R.21
Rubin, J.B.22
Alden, T.23
Browd, S.24
Geyer, J.R.25
Leary, S.26
Jallo, G.27
Cohen, K.28
Gupta, N.29
Prados, M.D.30
more..
-
90
-
-
84899559895
-
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
-
Taylor KR, Mackay A, Truffaux N, Butterfield YS, Morozova O, Philippe C, Castel D, Grasso CS, Vinci M, Carvalho D, Carcaboso AM, Torres C de, Cruz O, Mora J, Entz-Werle N, Ingram WJ, Monje M, Hargrave D, Bullock AN, Puget S, Yip S, Jones C, Grill J: Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. Nat Genet 2014, 46:457-61.
-
(2014)
Nat Genet
, vol.46
, pp. 457-461
-
-
Taylor, K.R.1
Mackay, A.2
Truffaux, N.3
Butterfield, Y.S.4
Morozova, O.5
Philippe, C.6
Castel, D.7
Grasso, C.S.8
Vinci, M.9
Carvalho, D.10
Carcaboso, A.M.11
Torres, C.12
De Cruz, O.13
Mora, J.14
Entz-Werle, N.15
Ingram, W.J.16
Monje, M.17
Hargrave, D.18
Bullock, A.N.19
Puget, S.20
Yip, S.21
Jones, C.22
Grill, J.23
more..
-
91
-
-
84899570180
-
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
-
Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Barszczyk M, Chornenkyy Y, Bourgey M, Bourque G, Montpetit A, Cordero F, Castelo-Branco P, Mangerel J, Tabori U, Ho KC, Huang A, Taylor KR, Mackay A, Bendel AE, Nazarian J, Fangusaro JR, Karajannis MA, et al.: Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nat Genet 2014, 46:451-6.
-
(2014)
Nat Genet
, vol.46
, pp. 451-456
-
-
Buczkowicz, P.1
Hoeman, C.2
Rakopoulos, P.3
Pajovic, S.4
Letourneau, L.5
Dzamba, M.6
Morrison, A.7
Lewis, P.8
Bouffet, E.9
Bartels, U.10
Zuccaro, J.11
Agnihotri, S.12
Ryall, S.13
Barszczyk, M.14
Chornenkyy, Y.15
Bourgey, M.16
Bourque, G.17
Montpetit, A.18
Cordero, F.19
Castelo-Branco, P.20
Mangerel, J.21
Tabori, U.22
Ho, K.C.23
Huang, A.24
Taylor, K.R.25
Mackay, A.26
Bendel, A.E.27
Nazarian, J.28
Fangusaro, J.R.29
Karajannis, M.A.30
more..
-
92
-
-
84896720721
-
A network of players in H3 histone variant deposition and maintenance at centromeres
-
Müller S, Almouzni G: A network of players in H3 histone variant deposition and maintenance at centromeres. Biochim Biophys Acta 2014, 1839:241-50.
-
(2014)
Biochim Biophys Acta
, vol.1839
, pp. 241-250
-
-
Müller, S.1
Almouzni, G.2
-
93
-
-
80053144962
-
A decade of exploring the cancer epigenome - biological and translational implications
-
Baylin SB, Jones PA: A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer 2011, 11:726-34.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
94
-
-
84867082035
-
Epigenetic cancer therapy: Rationales, targets and drugs
-
Rius M, Lyko F: Epigenetic cancer therapy: rationales, targets and drugs. Oncogene 2012, 31:4257-65.
-
(2012)
Oncogene
, vol.31
, pp. 4257-4265
-
-
Rius, M.1
Lyko, F.2
-
95
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodríguez-Paredes M, Esteller M: Cancer epigenetics reaches mainstream oncology. Nat Med 2011, 17:330-9.
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodríguez-Paredes, M.1
Esteller, M.2
-
96
-
-
73749088654
-
Epigenetic opportunities and challenges in cancer
-
Best JD, Carey N: Epigenetic opportunities and challenges in cancer. Drug Discov Today 2010, 15:65-70.
-
(2010)
Drug Discov Today
, vol.15
, pp. 65-70
-
-
Best, J.D.1
Carey, N.2
-
97
-
-
84899526966
-
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
-
Wu G, Diaz AK, Paugh BS, Rankin SL, Ju B, Li Y, Zhu X, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Ma X, Lu C, Nagahawatte P, Hedlund E, Rusch M, Pounds S, Lin T, Onar-Thomas A, Huether R, Kriwacki R, Parker M, Gupta P, Becksfort J, Wei L, Mulder HL, Boggs K, Vadodaria B, Yergeau D, et al.: The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat Genet 2014, 46:444-50.
-
(2014)
Nat Genet
, vol.46
, pp. 444-450
-
-
Wu, G.1
Diaz, A.K.2
Paugh, B.S.3
Rankin, S.L.4
Ju, B.5
Li, Y.6
Zhu, X.7
Qu, C.8
Chen, X.9
Zhang, J.10
Easton, J.11
Edmonson, M.12
Ma, X.13
Lu, C.14
Nagahawatte, P.15
Hedlund, E.16
Rusch, M.17
Pounds, S.18
Lin, T.19
Onar-Thomas, A.20
Huether, R.21
Kriwacki, R.22
Parker, M.23
Gupta, P.24
Becksfort, J.25
Wei, L.26
Mulder, H.L.27
Boggs, K.28
Vadodaria, B.29
Yergeau, D.30
more..
-
98
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
Lewis PW, Müller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, Garcia BA, Muir TW, Becher OJ, Allis CD: Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 2013, 340:857-61.
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Müller, M.M.2
Koletsky, M.S.3
Cordero, F.4
Lin, S.5
Banaszynski, L.A.6
Garcia, B.A.7
Muir, T.W.8
Becher, O.J.9
Allis, C.D.10
-
99
-
-
84881154753
-
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors
-
Black JC, Manning AL, van Rechem C, Kim J, Ladd B, Cho J, Pineda CM, Murphy N, Daniels DL, Montagna C, Lewis PW, Glass K, Allis CD, Dyson NJ, Getz G, Whetstine JR: KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors. Cell 2013, 154:541-55.
-
(2013)
Cell
, vol.154
, pp. 541-555
-
-
Black, J.C.1
Manning, A.L.2
Van Rechem, C.3
Kim, J.4
Ladd, B.5
Cho, J.6
Pineda, C.M.7
Murphy, N.8
Daniels, D.L.9
Montagna, C.10
Lewis, P.W.11
Glass, K.12
Allis, C.D.13
Dyson, N.J.14
Getz, G.15
Whetstine, J.R.16
-
100
-
-
84886864184
-
Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
-
Daigle SR, Olhava EJ, Therkelsen CA, Basavapathruni A, Jin L, Boriack-Sjodin PA, Allain CJ, Klaus CR, Raimondi A, Scott MP, Waters NJ, Chesworth R, Moyer MP, Copeland RA, Richon VM, Pollock RM: Potent inhibition of DOT1L as treatment of MLL-fusion leukemia. Blood 2013, 122:1017-25.
-
(2013)
Blood
, vol.122
, pp. 1017-1025
-
-
Daigle, S.R.1
Olhava, E.J.2
Therkelsen, C.A.3
Basavapathruni, A.4
Jin, L.5
Boriack-Sjodin, P.A.6
Allain, C.J.7
Klaus, C.R.8
Raimondi, A.9
Scott, M.P.10
Waters, N.J.11
Chesworth, R.12
Moyer, M.P.13
Copeland, R.A.14
Richon, V.M.15
Pollock, R.M.16
-
101
-
-
79952396960
-
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
-
Bantscheff M, Hopf C, Savitski MM, Dittmann A, Grandi P, Michon A, Schlegl J, Abraham Y, Becher I, Bergamini G, Boesche M, Delling M, Dümpelfeld B, Eberhard D, Huthmacher C, Mathieson T, Poeckel D, Reader V, Strunk K, Sweetman G, Kruse U, Neubauer G, Ramsden NG, Drewes G: Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol 2011, 29:255-65.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 255-265
-
-
Bantscheff, M.1
Hopf, C.2
Savitski, M.M.3
Dittmann, A.4
Grandi, P.5
Michon, A.6
Schlegl, J.7
Abraham, Y.8
Becher, I.9
Bergamini, G.10
Boesche, M.11
Delling, M.12
Dümpelfeld, B.13
Eberhard, D.14
Huthmacher, C.15
Mathieson, T.16
Poeckel, D.17
Reader, V.18
Strunk, K.19
Sweetman, G.20
Kruse, U.21
Neubauer, G.22
Ramsden, N.G.23
Drewes, G.24
more..
-
102
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE: Selective inhibition of BET bromodomains. Nature 2010, 468:1067-73.
-
(2010)
Nature
, vol.468
, pp. 1067-1073
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
Fedorov, O.6
Morse, E.M.7
Keates, T.8
Hickman, T.T.9
Felletar, I.10
Philpott, M.11
Munro, S.12
McKeown, M.R.13
Wang, Y.14
Christie, A.L.15
West, N.16
Cameron, M.J.17
Schwartz, B.18
Heightman, T.D.19
La Thangue, N.20
French, C.A.21
Wiest, O.22
Kung, A.L.23
Knapp, S.24
Bradner, J.E.25
more..
-
103
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung C, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A: Suppression of inflammation by a synthetic histone mimic. Nature 2010, 468:1119-23.
-
(2010)
Nature
, vol.468
, pp. 1119-1123
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
Beinke, S.4
Dewell, S.5
Chung, C.6
Chandwani, R.7
Marazzi, I.8
Wilson, P.9
Coste, H.10
White, J.11
Kirilovsky, J.12
Rice, C.M.13
Lora, J.M.14
Prinjha, R.K.15
Lee, K.16
Tarakhovsky, A.17
-
104
-
-
80052743686
-
Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors
-
Singh MM, Manton CA, Bhat KP, Tsai W, Aldape K, Barton MC, Chandra J: Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro-oncology 2011, 13:894-903.
-
(2011)
Neuro-oncology
, vol.13
, pp. 894-903
-
-
Singh, M.M.1
Manton, C.A.2
Bhat, K.P.3
Tsai, W.4
Aldape, K.5
Barton, M.C.6
Chandra, J.7
-
105
-
-
34250689152
-
Histone deacetylase inhibitor and demethylating agent chromatin compaction and the radiation response by cancer cells
-
Bar-Sela G, Jacobs KM, Gius D: Histone deacetylase inhibitor and demethylating agent chromatin compaction and the radiation response by cancer cells. Cancer J 2007, 13:65-9.
-
(2007)
Cancer J
, vol.13
, pp. 65-69
-
-
Bar-Sela, G.1
Jacobs, K.M.2
Gius, D.3
-
106
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong K, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J: A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 2010, 141:69-80.
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
McDermott, U.7
Azizian, N.8
Zou, L.9
Fischbach, M.A.10
Wong, K.11
Brandstetter, K.12
Wittner, B.13
Ramaswamy, S.14
Classon, M.15
Settleman, J.16
-
107
-
-
0028847955
-
Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4
-
Sobel RE, Cook RG, Perry CA, Annunziato AT, Allis CD: Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4. Proc Natl Acad Sci USA 1995, 92:1237-41.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1237-1241
-
-
Sobel, R.E.1
Cook, R.G.2
Perry, C.A.3
Annunziato, A.T.4
Allis, C.D.5
-
108
-
-
77950462427
-
Partitioning of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly
-
Xu M, Long C, Chen X, Huang C, Chen S, Zhu B: Partitioning of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly. Science 2010, 328:94-8.
-
(2010)
Science
, vol.328
, pp. 94-98
-
-
Xu, M.1
Long, C.2
Chen, X.3
Huang, C.4
Chen, S.5
Zhu, B.6
-
109
-
-
36049028058
-
New nomenclature for chromatin-modifying enzymes
-
Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y: New nomenclature for chromatin-modifying enzymes. Cell 2007, 131:633-6.
-
(2007)
Cell
, vol.131
, pp. 633-636
-
-
Allis, C.D.1
Berger, S.L.2
Cote, J.3
Dent, S.4
Jenuwien, T.5
Kouzarides, T.6
Pillus, L.7
Reinberg, D.8
Shi, Y.9
Shiekhattar, R.10
Shilatifard, A.11
Workman, J.12
Zhang, Y.13
|