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Volumn 195, Issue 2, 2014, Pages 107-114

Understanding drug resistance in malaria parasites: Basic science for public health

Author keywords

Antimalarial resistance; Drug selection; Genetics; Plasmodium falciparum

Indexed keywords

AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; ARTESUNATE; BENFLUMETOL; CHLOROQUINE; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FOLIC ACID ANTAGONIST; LUME; MEFLOQUINE; MOLECULAR MARKER; PIPERAQUINE; PYRIMETHAMINE; PYRIMETHAMINE PLUS SULFADOXINE; PYRONARIDINE; SULFADOXINE; UNCLASSIFIED DRUG;

EID: 84906938537     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2014.06.001     Document Type: Review
Times cited : (26)

References (97)
  • 1
    • 0242406973 scopus 로고    scopus 로고
    • Monitoring antimalarial drug resistance: Making the most of the tools at hand
    • DOI 10.1242/jeb.00658
    • C.V. Plowe Monitoring antimalarial drug resistance: making the most of the tools at hand J Exp Biol 206 2003 3745 3752 (Pubitemid 37365456)
    • (2003) Journal of Experimental Biology , vol.206 , Issue.21 , pp. 3745-3752
    • Plowe, C.V.1
  • 2
    • 84855293514 scopus 로고    scopus 로고
    • From bark to weed: The history of artemisinin
    • C. Faurant From bark to weed: the history of artemisinin Parasite 18 2011 215 218
    • (2011) Parasite , vol.18 , pp. 215-218
    • Faurant, C.1
  • 3
    • 79956282726 scopus 로고    scopus 로고
    • Quinine, an old anti-malarial drug in a modern world: Role in the treatment of malaria
    • J. Achan, A.O. Talisuna, A. Erhart, A. Yeka, J.K. Tibenderana, and F.N. Baliraine et al. Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria Malar J 10 2011 144
    • (2011) Malar J , vol.10 , pp. 144
    • Achan, J.1    Talisuna, A.O.2    Erhart, A.3    Yeka, A.4    Tibenderana, J.K.5    Baliraine, F.N.6
  • 4
    • 73349086226 scopus 로고    scopus 로고
    • The long shadow of malaria interventions in tropical Africa
    • J.L.A. Webb The long shadow of malaria interventions in tropical Africa Lancet 374 2009 1883 1884
    • (2009) Lancet , vol.374 , pp. 1883-1884
    • Webb, J.L.A.1
  • 5
    • 0026014936 scopus 로고
    • Geographic approach to the epidemiology of chloroquine-resistance of Plasmodium falciparum in tropical Africa
    • G. Charmot, J. Amat-Roze, F. Rodhain, J. Le Bras, and J. Coulaud Geographic approach to the epidemiology of chloroquine-resistance of Plasmodium falciparum in tropical Africa Ann Soc Belg Med Trop 71 1991 187 197
    • (1991) Ann Soc Belg Med Trop , vol.71 , pp. 187-197
    • Charmot, G.1    Amat-Roze, J.2    Rodhain, F.3    Le Bras, J.4    Coulaud, J.5
  • 6
    • 31444454856 scopus 로고    scopus 로고
    • second ed. World Health Organization [accessed 21.05.14]
    • WHO Guidelines for treatment of malaria second ed. 2010 World Health Organization http://www.who.int/malaria/publications/atoz/9789241547925/en/ index.html [accessed 21.05.14]
    • (2010) Guidelines for Treatment of Malaria
  • 7
    • 0017311840 scopus 로고
    • Human malaria parasites in continous culture
    • W. Trager, and J.B. Jensen Human malaria parasites in continous culture Science 193 1976 673 675
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.1    Jensen, J.B.2
  • 8
    • 0018606732 scopus 로고
    • Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
    • R.E. Desjardins, C.J. Canfield, J.H. Haynes, and J.D. Chulay Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique Antimicrob Agents Chemother 16 1979 710 718 (Pubitemid 10082023)
    • (1979) Antimicrobial Agents and Chemotherapy , vol.16 , Issue.6 , pp. 710-718
    • Desjardins, R.E.1    Canfield, C.J.2    Haynes, J.D.3    Chulay, J.D.4
  • 9
    • 0032698219 scopus 로고    scopus 로고
    • A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum [see comments]
    • X. Su, M.T. Ferdig, Y. Huang, C.Q. Huynh, A. Liu, and J. You et al. A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum [see comments] Science 286 1999 1351 1353
    • (1999) Science , vol.286 , pp. 1351-1353
    • Su, X.1    Ferdig, M.T.2    Huang, Y.3    Huynh, C.Q.4    Liu, A.5    You, J.6
  • 10
    • 0033636607 scopus 로고    scopus 로고
    • Mutations in the P. Falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
    • D.A. Fidock, T. Nomura, A.K. Talley, R.A. Cooper, S.M. Dzekunov, and M.T. Ferdig et al. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance Mol Cell 6 2000 861 871
    • (2000) Mol Cell , vol.6 , pp. 861-871
    • Fidock, D.A.1    Nomura, T.2    Talley, A.K.3    Cooper, R.A.4    Dzekunov, S.M.5    Ferdig, M.T.6
  • 11
    • 84879195625 scopus 로고    scopus 로고
    • Function of resistance conferring Plasmodium falciparum chloroquine resistance transporter isoforms
    • N.K. Baro, P.S. Callaghan, and P.D. Roepe Function of resistance conferring Plasmodium falciparum chloroquine resistance transporter isoforms Biochemistry 52 2013 4242 4249
    • (2013) Biochemistry , vol.52 , pp. 4242-4249
    • Baro, N.K.1    Callaghan, P.S.2    Roepe, P.D.3
  • 13
    • 0035946415 scopus 로고    scopus 로고
    • Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum
    • DOI 10.1016/S0166-6851(01)00247-X, PII S016668510100247X
    • R. Durand, S. Jafari, J. Vauzelle, J.F. Delabre, Z. Jesic, and J. Le Bras Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum Mol Biochem Parasitol 114 2001 95 102 (Pubitemid 32453219)
    • (2001) Molecular and Biochemical Parasitology , vol.114 , Issue.1 , pp. 95-102
    • Durand, R.1    Jafari, S.2    Vauzelle, J.3    Delabre, J.-F.4    Jesic, Z.5    Le Bras, J.6
  • 15
    • 0037130254 scopus 로고    scopus 로고
    • Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum
    • DOI 10.1038/nature00813
    • J.C. Wootton, X. Feng, M.T. Ferdig, R.A. Cooper, J. Mu, and D.I. Baruch et al. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum Nature 418 2002 320 323 (Pubitemid 34790681)
    • (2002) Nature , vol.418 , Issue.6895 , pp. 320-323
    • Wootton, J.C.1    Feng, X.2    Ferdig, M.T.3    Cooper, R.A.4    Mu, J.5    Baruch, D.I.6    Magill, A.J.7    Su, X.-Z.8
  • 16
    • 0025269612 scopus 로고
    • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum [see comments]
    • S.J. Foote, D.E. Kyle, R.K. Martin, A.M. Oduola, K. Forsyth, and D.J. Kemp et al. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum [see comments] Nature 345 1990 255 258
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, A.M.4    Forsyth, K.5    Kemp, D.J.6
  • 17
    • 0029586497 scopus 로고
    • Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa
    • DOI 10.1016/0166-6851(95)02492-1
    • L.K. Basco, J. Le Bras, Z. Rhoades, and C.M. Wilson Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa Molec Biochem Parasitol 74 1995 157 166 (Pubitemid 26024474)
    • (1995) Molecular and Biochemical Parasitology , vol.74 , Issue.2 , pp. 157-166
    • Basco, L.K.1    Le Bras, J.2    Rhoades, Z.3    Wilson, C.M.4
  • 18
    • 0034732666 scopus 로고    scopus 로고
    • The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin
    • DOI 10.1016/S0166-6851(00)00201-2, PII S0166685100002012
    • M. Duraisingh, P. Jones, I. Sambou, L. von Seidlein, M. Pinder, and D. Warhurst The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin Mol Biochem Parasitol 108 2000 13 23 (Pubitemid 30236312)
    • (2000) Molecular and Biochemical Parasitology , vol.108 , Issue.1 , pp. 13-23
    • Duraisingh, M.T.1    Jones, P.2    Sambou, I.3    Von Seidlein, L.4    Pinder, M.5    Warhurst, D.C.6
  • 19
    • 0141817683 scopus 로고    scopus 로고
    • Short report: Association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan
    • E.O. Ochong, I.V. van den Broek, K. Keus, and A. Nzila Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan Am J Trop Med Hyg 69 2003 184 187
    • (2003) Am J Trop Med Hyg , vol.69 , pp. 184-187
    • Ochong, E.O.1    Van Den Broek, I.V.2    Keus, K.3    Nzila, A.4
  • 20
    • 0032804039 scopus 로고    scopus 로고
    • The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand
    • R.N. Price, C. Cassar, A. Brockman, M. Duraisingh, M. van Vugt, and N.J. White et al. The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand Antimicrob Agents Chemother 43 1999 2943 2949
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 2943-2949
    • Price, R.N.1    Cassar, C.2    Brockman, A.3    Duraisingh, M.4    Van Vugt, M.5    White, N.J.6
  • 24
    • 0002361779 scopus 로고
    • Observations on monthly pyrimethamine (daraprim) prophylaxis in an East African village
    • D.F. Clyde Observations on monthly pyrimethamine (daraprim) prophylaxis in an East African village East Afr Med J 31 1954 41 46
    • (1954) East Afr Med J , vol.31 , pp. 41-46
    • Clyde, D.F.1
  • 25
    • 84906935183 scopus 로고
    • Plasmodium falciparum resistant to pyrimethamine in non-immune Europeans in Tanganyika
    • D.F. Clyde Plasmodium falciparum resistant to pyrimethamine in non-immune Europeans in Tanganyika East Afr Med J 35 1958 181 186
    • (1958) East Afr Med J , vol.35 , pp. 181-186
    • Clyde, D.F.1
  • 26
    • 14144254535 scopus 로고
    • Potentiation of the antimalarial activity of sulfadiazine by 2,4-diamino-5-aryloxypyrimidines
    • J. Greenberg, and E.M. Richeson Potentiation of the antimalarial activity of sulfadiazine by 2,4-diamino-5-aryloxypyrimidines J Pharmacol Exp Ther 99 1950 444 449
    • (1950) J Pharmacol Exp Ther , vol.99 , pp. 444-449
    • Greenberg, J.1    Richeson, E.M.2
  • 27
    • 0000478463 scopus 로고
    • The biosynthesis of folic acid. II: Inhibition of sulfonamides
    • G.M. Brown The biosynthesis of folic acid. II: Inhibition of sulfonamides J Biol Chem 237 1962 536 540
    • (1962) J Biol Chem , vol.237 , pp. 536-540
    • Brown, G.M.1
  • 32
    • 0033081157 scopus 로고    scopus 로고
    • The mechanism of resistance to sulfa drugs in Plasmodium falciparum
    • DOI 10.1054/drup.1998.0060
    • T. Triglia, and A.F. Cowman The mechanism of resistance to sulfa drugs in Plasmodium falciparum Drug Resist Update 2 1999 15 19 (Pubitemid 29217090)
    • (1999) Drug Resistance Updates , vol.2 , Issue.1 , pp. 15-19
    • Triglia, T.1    Cowman, A.F.2
  • 33
    • 0032079104 scopus 로고    scopus 로고
    • Plasmodium falciparum: Detection of polymorphisms in the dihydrofolate reductase and dihydropferoate synthetase genes by PCR and restriction digestion
    • DOI 10.1006/expr.1998.4274
    • M.T. Duraisingh, J. Curtis, and D.C. Warhurst Plasmodium falciparum: detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion Exp Parasitol 89 1998 1 8 (Pubitemid 28377366)
    • (1998) Experimental Parasitology , vol.89 , Issue.1 , pp. 1-8
    • Duraisingh, M.T.1    Curtis, J.2    Warhurst, D.C.3
  • 35
    • 24144480947 scopus 로고    scopus 로고
    • Antimalarial drug resistance in Africa: Strategies for monitoring and deterrence
    • C. Plowe Antimalarial drug resistance in Africa: strategies for monitoring and deterrence Curr Top Microbiol Immunol 295 2005 55 79 (Pubitemid 41236511)
    • (2005) Current Topics in Microbiology and Immunology , vol.295 , pp. 55-79
    • Plowe, C.V.1
  • 36
    • 65649126746 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria
    • S. Picot, P. Olliaro, F. de Monbrison, A. Bienvenu, R. Price, and P. Ringwald A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria Malar J 8 2009 89
    • (2009) Malar J , vol.8 , pp. 89
    • Picot, S.1    Olliaro, P.2    De Monbrison, F.3    Bienvenu, A.4    Price, R.5    Ringwald, P.6
  • 37
    • 84861463927 scopus 로고    scopus 로고
    • Monitoring antimalarial drug resistance: Applying lessons learned from the past in a fast-moving present
    • C.H. Sibley, and R.N. Price Monitoring antimalarial drug resistance: applying lessons learned from the past in a fast-moving present Int J Parasitol: Drugs Drug Resist 2 2012 126 133
    • (2012) Int J Parasitol: Drugs Drug Resist , vol.2 , pp. 126-133
    • Sibley, C.H.1    Price, R.N.2
  • 38
    • 0030632921 scopus 로고    scopus 로고
    • In vitro sensitivity of Plasmodium falciparum to anti-folinic agents (trimethoprim, pyrimethamine, cycloguanil): A study of 29 African strains
    • L.K. Basco, and J. Le Bras In vitro sensitivity of Plasmodium falciparum to anti-folinic agents (trimethoprim, pyrimethamine, cycloguanil): a study of 29 African strains Bull Soc Pathol Exot 90 1997 90 93
    • (1997) Bull Soc Pathol Exot , vol.90 , pp. 90-93
    • Basco, L.K.1    Le Bras, J.2
  • 39
    • 0030868588 scopus 로고    scopus 로고
    • A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance
    • DOI 10.1017/S0031182097001431
    • P. Wang, P.F. Sims, and J.E. Hyde A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance Parasitology 115 1997 223 230 (Pubitemid 27394548)
    • (1997) Parasitology , vol.115 , Issue.3 , pp. 223-230
    • Wang, P.1    Sims, P.F.G.2    Hyde, J.E.3
  • 40
    • 0031807606 scopus 로고    scopus 로고
    • Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites
    • L.K. Basco, R. Tahar, and P. Ringwald Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites Antimicrob Agents Chemother 42 1998 1811 1814 (Pubitemid 28311584)
    • (1998) Antimicrobial Agents and Chemotherapy , vol.42 , Issue.7 , pp. 1811-1814
    • Basco, L.K.1    Tahar, R.2    Ringwald, P.3
  • 42
    • 77949634490 scopus 로고    scopus 로고
    • P. Falciparum dihydrofolate reductase and dihydropteroate synthase mutations: Epidemiology and role in clinical resistance to antifolates
    • C.V. Plowe, J.G. Kublin, and O.K. Doumbo P. falciparum dihydrofolate reductase and dihydropteroate synthase mutations: epidemiology and role in clinical resistance to antifolates Drug Resist Update 1 1998 389 396
    • (1998) Drug Resist Update , vol.1 , pp. 389-396
    • Plowe, C.V.1    Kublin, J.G.2    Doumbo, O.K.3
  • 43
    • 0035883813 scopus 로고    scopus 로고
    • Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria
    • DOI 10.1016/S0140-6736(01)06040-8
    • A. Djimde, O.K. Doumbo, R.W. Steketee, and C.V. Plowe Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria Lancet 358 2001 890 891 (Pubitemid 32900575)
    • (2001) Lancet , vol.358 , Issue.9285 , pp. 890-891
    • Djimde, A.1    Doumbo, O.K.2    Steketee, R.W.3    Plowe, C.V.4
  • 46
    • 7944224830 scopus 로고    scopus 로고
    • Withdrawing antimalarial drugs: Impact on parasite resistance and implications for malaria treatment policies
    • DOI 10.1016/j.drup.2004.08.003, PII S1368764604000676
    • M. Laufer, and C. Plowe Withdrawing antimalarial drugs: impact on parasite resistance and implications for malaria treatment policies Drug Resist Update 7 2004 279 288 (Pubitemid 39469100)
    • (2004) Drug Resistance Updates , vol.7 , Issue.4-5 , pp. 279-288
    • Laufer, M.K.1    Plowe, C.V.2
  • 48
    • 34250178810 scopus 로고    scopus 로고
    • Molecular surveillance for drug-resistant Plasmodium falciparum malaria in Malawi
    • DOI 10.1016/j.actatropica.2007.04.006, PII S0001706X07001003
    • S. Nkhoma, M. Molyneux, and S. Ward Molecular surveillance for drug-resistant Plasmodium falciparum malaria in Malawi Acta Trop 102 2007 138 142 (Pubitemid 46898951)
    • (2007) Acta Tropica , vol.102 , Issue.2 , pp. 138-142
    • Nkhoma, S.1    Molyneux, M.2    Ward, S.3
  • 49
    • 80053173475 scopus 로고    scopus 로고
    • Knowledge and malaria treatment practices using artemisinin combination therapy (ACT) in Malawi: Survey of health professionals
    • L. Kalilani-Phiri, D. Lungu, and R. Coghlan Knowledge and malaria treatment practices using artemisinin combination therapy (ACT) in Malawi: survey of health professionals Malar J 10 2011 279
    • (2011) Malar J , vol.10 , pp. 279
    • Kalilani-Phiri, L.1    Lungu, D.2    Coghlan, R.3
  • 51
    • 0036786291 scopus 로고    scopus 로고
    • Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America
    • J.F. Cortese, A. Caraballo, C.E. Contreras, and C.V. Plowe Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America J Infect Dis 186 2002 999 1000
    • (2002) J Infect Dis , vol.186 , pp. 999-1000
    • Cortese, J.F.1    Caraballo, A.2    Contreras, C.E.3    Plowe, C.V.4
  • 53
    • 0037420464 scopus 로고    scopus 로고
    • Antifolate antimalarial resistance in southeast Africa: A population-based analysis
    • DOI 10.1016/S0140-6736(03)12951-0
    • C. Roper, R. Pearce, B. Bredenkamp, J. Gumede, C. Drakeley, and F. Mosha et al. Antifolate antimalarial resistance in southeast Africa: a population-based analysis Lancet 361 2003 1174 1181 (Pubitemid 36398386)
    • (2003) Lancet , vol.361 , Issue.9364 , pp. 1174-1181
    • Roper, C.1    Pearce, R.2    Bredenkamp, B.3    Gumede, J.4    Drakeley, C.5    Mosha, F.6    Chandramohan, D.7    Sharp, B.8
  • 54
    • 4143103433 scopus 로고    scopus 로고
    • Intercontinental spread of pyrimethamine-resistant malaria
    • DOI 10.1126/science.1098876
    • C. Roper, R. Pearce, S. Nair, B. Sharp, F. Nosten, and T. Anderson Intercontinental spread of pyrimethamine-resistant malaria Science 305 2004 1124 (Pubitemid 39100317)
    • (2004) Science , vol.305 , Issue.5687 , pp. 1124
    • Roper, C.1    Pearce, R.2    Nair, S.3    Sharp, B.4    Nosten, F.5    Anderson, T.6
  • 55
    • 34347359955 scopus 로고    scopus 로고
    • Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use
    • N. Noranate, R. Durand, A. Tall, L. Marrama, A. Spiegel, and C. Sokhna et al. Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use PLoS ONE 2 2007 e139
    • (2007) PLoS ONE , vol.2 , pp. 139
    • Noranate, N.1    Durand, R.2    Tall, A.3    Marrama, L.4    Spiegel, A.5    Sokhna, C.6
  • 56
    • 46349109273 scopus 로고    scopus 로고
    • Characteristics of Plasmodium falciparum dhfr haplotypes that confer pyrimethamine resistance, Kilifi, Kenya, 1987-2006
    • DOI 10.1086/588198
    • L.K. Certain, M. Briceno, S.M. Kiara, A.M. Nzila, W.M. Watkins, and C.H. Sibley Characteristics of Plasmodium falciparum dhfr haplotypes that confer pyrimethamine resistance, Kilifi, Kenya, 1987-2006 J Infect Dis 197 2008 1743 1751 (Pubitemid 351919640)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.12 , pp. 1743-1751
    • Certain, L.K.1    Briceno, M.2    Kiara, S.M.3    Nzila, A.M.4    Watkins, W.M.5    Sibley, C.H.6
  • 58
    • 77954918996 scopus 로고    scopus 로고
    • Drug coverage in treatment of malaria and the consequences for resistance evolution - Evidence from the use of sulphadoxine/pyrimethamine
    • A.L. Malisa, R.J. Pearce, S. Abdulla, H. Mshinda, P.S. Kachur, and P. Bloland et al. Drug coverage in treatment of malaria and the consequences for resistance evolution - evidence from the use of sulphadoxine/pyrimethamine Malar J 9 2010 190
    • (2010) Malar J , vol.9 , pp. 190
    • Malisa, A.L.1    Pearce, R.J.2    Abdulla, S.3    Mshinda, H.4    Kachur, P.S.5    Bloland, P.6
  • 59
    • 65449188363 scopus 로고    scopus 로고
    • Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria
    • R.J. Pearce, H. Pota, M.S. Evehe, H. Ba el, G. Mombo-Ngoma, and A.L. Malisa et al. Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria PLoS Med 6 2009 e1000055
    • (2009) PLoS Med , vol.6 , pp. 1000055
    • Pearce, R.J.1    Pota, H.2    Evehe, M.S.3    Ba El, H.4    Mombo-Ngoma, G.5    Malisa, A.L.6
  • 62
    • 0034978186 scopus 로고    scopus 로고
    • The public health impact of chloroquine resistance in Africa
    • J.F. Trape The public health impact of chloroquine resistance in Africa Am J Trop Med Hyg 64 2001 12 17
    • (2001) Am J Trop Med Hyg , vol.64 , pp. 12-17
    • Trape, J.F.1
  • 64
    • 0035700572 scopus 로고    scopus 로고
    • The past, present and future of childhood malaria mortality in Africa
    • DOI 10.1016/S1471-4922(01)02031-1, PII S1471492201020311
    • R.W. Snow, J.F. Trape, and K. Marsh The past, present and future of childhood malaria mortality in Africa Trends Parasitol 17 2001 593 597 (Pubitemid 34088120)
    • (2001) Trends in Parasitology , vol.17 , Issue.12 , pp. 593-597
    • Snow, R.W.1    Trape, J.-F.2    Marsh, K.3
  • 65
    • 67650397861 scopus 로고    scopus 로고
    • Spread and evolution of Plasmodium falciparum drug resistance
    • T. Mita, K. Tanabe, and K. Kita Spread and evolution of Plasmodium falciparum drug resistance Parasitol Int 58 2009 201 209
    • (2009) Parasitol Int , vol.58 , pp. 201-209
    • Mita, T.1    Tanabe, K.2    Kita, K.3
  • 66
    • 0030271322 scopus 로고    scopus 로고
    • Strategies for the prevention of antimalarial drug resistance: Rationale for combination chemotherapy for malaria
    • DOI 10.1016/0169-4758(96)10055-7
    • N. White, and P. Olliaro Strategies for the prevention of antimalarial drug resistance: rationale for combination chemotherapy for malaria Parasitol Today 12 1996 399 401 (Pubitemid 26306804)
    • (1996) Parasitology Today , vol.12 , Issue.10 , pp. 399-401
    • White, N.J.1    Olliaro, P.L.2
  • 67
    • 0034702506 scopus 로고    scopus 로고
    • Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: A prospective study
    • F. Nosten, M. van Vugt, R. Price, C. Luxemburger, K.L. Thway, and A. Brockman et al. Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study Lancet 356 2000 297 302 (Pubitemid 30459588)
    • (2000) Lancet , vol.356 , Issue.9226 , pp. 297-302
    • Nosten, F.1    Van Vugt, M.2    Price, R.3    Luxemburger, C.4    Thway, K.L.5    Brockman, A.6    McGready, R.7    Ter Kuile, F.8    Looareesuwan, S.9    White, N.J.10
  • 68
  • 69
    • 84887989421 scopus 로고    scopus 로고
    • Antimalarial drug discovery [mdash] approaches and progress towards new medicines
    • E.L. Flannery, A.K. Chatterjee, and E.A. Winzeler Antimalarial drug discovery [mdash] approaches and progress towards new medicines Nat Rev Microbiol 11 2013 849 862
    • (2013) Nat Rev Microbiol , vol.11 , pp. 849-862
    • Flannery, E.L.1    Chatterjee, A.K.2    Winzeler, E.A.3
  • 70
    • 77950192277 scopus 로고    scopus 로고
    • World malaria report
    • Organization WH [accessed 21.05.14]
    • WHO World malaria report Organization WH Geneva 2013 2013 http://apps.who.int/iris/handle/10665/43417 [accessed 21.05.14]
    • (2013) Geneva 2013
  • 71
    • 84884719955 scopus 로고    scopus 로고
    • Fighting drug-resistant Plasmodium falciparum: The challenge of artemisinin resistance
    • C. Wongsrichanalai, and C.H. Sibley Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance Clin Microbiol Infect 19 2013 908 916
    • (2013) Clin Microbiol Infect , vol.19 , pp. 908-916
    • Wongsrichanalai, C.1    Sibley, C.H.2
  • 72
    • 0033182170 scopus 로고    scopus 로고
    • Delaying antimalarial drug resistance with combination chemotherapy
    • N.J. White Delaying antimalarial drug resistance with combination chemotherapy Parassitology 41 1999 301 308
    • (1999) Parassitology , vol.41 , pp. 301-308
    • White, N.J.1
  • 74
    • 80755143047 scopus 로고    scopus 로고
    • Standardizing the measurement of parasite clearance in falciparum malaria: The parasite clearance estimator
    • J.A. Flegg, P.J. Guerin, N.J. White, and K. Stepniewska Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator Malar J 10 2011 339
    • (2011) Malar J , vol.10 , pp. 339
    • Flegg, J.A.1    Guerin, P.J.2    White, N.J.3    Stepniewska, K.4
  • 75
    • 77950943615 scopus 로고    scopus 로고
    • High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia
    • T.J. Anderson, S. Nair, S. Nkhoma, J.T. Williams, M. Imwong, and P. Yi et al. High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia J Infect Dis 201 2010 1326 1330
    • (2010) J Infect Dis , vol.201 , pp. 1326-1330
    • Anderson, T.J.1    Nair, S.2    Nkhoma, S.3    Williams, J.T.4    Imwong, M.5    Yi, P.6
  • 76
    • 84861461519 scopus 로고    scopus 로고
    • Emergence of artemisinin-resistant malaria on the western border of Thailand: A longitudinal study
    • A.P. Phyo, S. Nkhoma, K. Stepniewska, E.A. Ashley, S. Nair, and R. McGready et al. Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study Lancet 379 2012 1960 1966
    • (2012) Lancet , vol.379 , pp. 1960-1966
    • Phyo, A.P.1    Nkhoma, S.2    Stepniewska, K.3    Ashley, E.A.4    Nair, S.5    McGready, R.6
  • 77
    • 79959612992 scopus 로고    scopus 로고
    • World Health Organization Geneva [accessed 21.05.14]
    • WHO Global plan for atemisinin resistance containment 2011 World Health Organization Geneva http://www.who.int/malaria/publications/atoz/9789241500838/ en/index.html [accessed 21.05.14]
    • (2011) Global Plan for Atemisinin Resistance Containment
  • 79
    • 0037015614 scopus 로고    scopus 로고
    • Genome sequence of the human malaria parasite Plasmodium falciparum
    • M.J. Gardner, N. Hall, E. Fung, O. White, M. Berriman, and R.W. Hyman et al. Genome sequence of the human malaria parasite Plasmodium falciparum Nature 419 2002 498 511
    • (2002) Nature , vol.419 , pp. 498-511
    • Gardner, M.J.1    Hall, N.2    Fung, E.3    White, O.4    Berriman, M.5    Hyman, R.W.6
  • 80
    • 84863982076 scopus 로고    scopus 로고
    • Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
    • M. Manske, O. Miotto, S. Campino, S. Auburn, J. Almagro-Garcia, and G. Maslen et al. Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing Nature 487 2012 375 379
    • (2012) Nature , vol.487 , pp. 375-379
    • Manske, M.1    Miotto, O.2    Campino, S.3    Auburn, S.4    Almagro-Garcia, J.5    Maslen, G.6
  • 81
    • 84859506329 scopus 로고    scopus 로고
    • A major genome region underlying artemisinin resistance in malaria
    • I.H. Cheeseman, B.A. Miller, S. Nair, S. Nkhoma, A. Tan, and J.C. Tan et al. A major genome region underlying artemisinin resistance in malaria Science 336 2012 79 82
    • (2012) Science , vol.336 , pp. 79-82
    • Cheeseman, I.H.1    Miller, B.A.2    Nair, S.3    Nkhoma, S.4    Tan, A.5    Tan, J.C.6
  • 82
    • 84871944250 scopus 로고    scopus 로고
    • Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia
    • S. Takala-Harrison, T.G. Clark, C.G. Jacob, M.P. Cummings, O. Miotto, and A.M. Dondorp et al. Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia Proc Natl Acad Sci U S A 110 2013 240 245
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 240-245
    • Takala-Harrison, S.1    Clark, T.G.2    Jacob, C.G.3    Cummings, M.P.4    Miotto, O.5    Dondorp, A.M.6
  • 83
  • 84
    • 84872858923 scopus 로고    scopus 로고
    • Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in Western Cambodia
    • B. Witkowski, N. Khim, P. Chim, S. Kim, S. Ke, and N. Kloeung et al. Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in Western Cambodia Antimicrob Agents Chemother 57 2013 914 923
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 914-923
    • Witkowski, B.1    Khim, N.2    Chim, P.3    Kim, S.4    Ke, S.5    Kloeung, N.6
  • 85
    • 0030152851 scopus 로고    scopus 로고
    • In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs
    • DOI 10.1016/0020-7519(96)89380-5
    • T.S. Skinner, L.S. Manning, W.A. Johnston, and T.M.E. Davis In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs Int J Parasitol 26 1996 519 525 (Pubitemid 26244548)
    • (1996) International Journal for Parasitology , vol.26 , Issue.5 , pp. 519-525
    • Skinner, T.S.1    Manning, L.S.2    Johnston, W.A.3    Davis, T.M.E.4
  • 86
    • 0027280310 scopus 로고
    • Plasmodium falciparum: In vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria
    • DOI 10.1006/expr.1993.1010
    • F. ter Kuile, N.J. White, P. Holloway, G. Pasvol, and S. Krishna Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria Exp Parasitol 76 1993 85 95 (Pubitemid 23197907)
    • (1993) Experimental Parasitology , vol.76 , Issue.1 , pp. 85-95
    • Ter Kuile, F.1    White, N.J.2    Holloway, P.3    Pasvol, G.4    Krishna, S.5
  • 87
    • 84887622121 scopus 로고    scopus 로고
    • Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: In vitro and ex vivo drug-response studies
    • B. Witkowski, C. Amaratunga, N. Khim, S. Sreng, P. Chim, and S. Kim et al. Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in vitro and ex vivo drug-response studies Lancet Infect Dis 13 2013 1043 1049
    • (2013) Lancet Infect Dis , vol.13 , pp. 1043-1049
    • Witkowski, B.1    Amaratunga, C.2    Khim, N.3    Sreng, S.4    Chim, P.5    Kim, S.6
  • 88
  • 89
    • 0033961690 scopus 로고    scopus 로고
    • The kelch repeat superfamily of proteins: Propellers of cell function
    • DOI 10.1016/S0962-8924(99)01673-6, PII S0962892499016736
    • J. Adams, R. Kelso, and L. Cooley The kelch repeat superfamily of proteins: propellers of cell function Trends Cell Biol 10 2000 17 24 (Pubitemid 30017862)
    • (2000) Trends in Cell Biology , vol.10 , Issue.1 , pp. 17-24
    • Adams, J.1    Kelso, R.2    Cooley, L.3
  • 90
    • 84856431125 scopus 로고    scopus 로고
    • Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities
    • L.M. Boyden, M. Choi, K.A. Choate, C.J. Nelson-Williams, A. Farhi, and H.R. Toka et al. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities Nature 482 2012 98 102
    • (2012) Nature , vol.482 , pp. 98-102
    • Boyden, L.M.1    Choi, M.2    Choate, K.A.3    Nelson-Williams, C.J.4    Farhi, A.5    Toka, H.R.6
  • 92
    • 63149179142 scopus 로고    scopus 로고
    • The last man standing is the most resistant: Eliminating artemisinin-resistant malaria in Cambodia
    • R.J. Maude, W. Pontavornpinyo, S. Saralamba, R. Aguas, S. Yeung, and A.M. Dondorp et al. The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia Malar J 8 2009 31
    • (2009) Malar J , vol.8 , pp. 31
    • Maude, R.J.1    Pontavornpinyo, W.2    Saralamba, S.3    Aguas, R.4    Yeung, S.5    Dondorp, A.M.6
  • 94
    • 84906937961 scopus 로고    scopus 로고
    • Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: Parasite risk factors that affect treatment outcomes for P. Falciparum Malaria after Artemether-Lumefantrine and Artesunate-Amodiaquine
    • M. Venkatesan, N.B. Gadalla, K. Stepniewska, P. Dahal, C. Nsanzabana, and C. Moriera et al. Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum Malaria after Artemether-Lumefantrine and Artesunate-Amodiaquine Am J Trop Med Hyg 2014
    • (2014) Am J Trop Med Hyg
    • Venkatesan, M.1    Gadalla, N.B.2    Stepniewska, K.3    Dahal, P.4    Nsanzabana, C.5    Moriera, C.6
  • 96
    • 84865176348 scopus 로고    scopus 로고
    • A framework for assessing the risk of resistance for anti-malarials in development
    • X. Ding, D. Ubben, and T. Wells A framework for assessing the risk of resistance for anti-malarials in development Malar J 11 2012 292
    • (2012) Malar J , vol.11 , pp. 292
    • Ding, X.1    Ubben, D.2    Wells, T.3
  • 97
    • 84903195977 scopus 로고    scopus 로고
    • Comparative impacts over 5 years of artemisinin-based combination therapies on P. Falciparum polymorphisms that modulate drug sensitivity in Ugandan children
    • M.D. Conrad, N. LeClair, E. Arinaitwe, H. Wanzira, A. Kakuru, and V. Bigira et al. Comparative impacts over 5 years of artemisinin-based combination therapies on P. falciparum polymorphisms that modulate drug sensitivity in Ugandan children J Infect Dis 2014
    • (2014) J Infect Dis
    • Conrad, M.D.1    Leclair, N.2    Arinaitwe, E.3    Wanzira, H.4    Kakuru, A.5    Bigira, V.6


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