-
1
-
-
24144455319
-
Mutations associated with sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre
-
Alker A.P., Mwapasa V., Purfield A., Rogerson S.J., Molyneux M.E., Kamwendo D.D., Tadesse E., Chaluluka E., and Meshnick S.R. Mutations associated with sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre. Antimicrob. Agents. Chemother. 49 (2005) 3919-3921
-
(2005)
Antimicrob. Agents. Chemother.
, vol.49
, pp. 3919-3921
-
-
Alker, A.P.1
Mwapasa, V.2
Purfield, A.3
Rogerson, S.J.4
Molyneux, M.E.5
Kamwendo, D.D.6
Tadesse, E.7
Chaluluka, E.8
Meshnick, S.R.9
-
2
-
-
0028021624
-
Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine
-
Brooks D.R., Wang P., Read M., Watkins W.M., Sims P.F., and Hyde J.E. Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. Eur. J. Biochem. 224 (1994) 397-405
-
(1994)
Eur. J. Biochem.
, vol.224
, pp. 397-405
-
-
Brooks, D.R.1
Wang, P.2
Read, M.3
Watkins, W.M.4
Sims, P.F.5
Hyde, J.E.6
-
3
-
-
0000854414
-
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum
-
Cowman A.F., Morry M.J., Biggs B.A., Cross G.A., and Foote S.J. Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 9109-9113
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 9109-9113
-
-
Cowman, A.F.1
Morry, M.J.2
Biggs, B.A.3
Cross, G.A.4
Foote, S.J.5
-
4
-
-
0037114995
-
Mutations in dhfr in Plasmodium falciparum infections selected by chlorproguanil-dapsone treatment
-
Curtis J., Maxwell C.A., Msuya F.H., Mkongewa S., Alloueche A., and Warhurst D.C. Mutations in dhfr in Plasmodium falciparum infections selected by chlorproguanil-dapsone treatment. J. Infect. Dis. 186 (2002) 1861-1864
-
(2002)
J. Infect. Dis.
, vol.186
, pp. 1861-1864
-
-
Curtis, J.1
Maxwell, C.A.2
Msuya, F.H.3
Mkongewa, S.4
Alloueche, A.5
Warhurst, D.C.6
-
5
-
-
0035945682
-
A molecular marker for chloroquine-resistant falciparum malaria
-
Djimdé A., Doumbo O.K., Cortese J.F., Kayentao K., Doumbo S., Diourte Y., Dicko A., Su X., Nomura T., Fidock D.A., Wellems T.E., and Plowe C.V. A molecular marker for chloroquine-resistant falciparum malaria. N. Engl. J. Med. 344 (2001) 257-263
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 257-263
-
-
Djimdé, A.1
Doumbo, O.K.2
Cortese, J.F.3
Kayentao, K.4
Doumbo, S.5
Diourte, Y.6
Dicko, A.7
Su, X.8
Nomura, T.9
Fidock, D.A.10
Wellems, T.E.11
Plowe, C.V.12
-
6
-
-
0035883813
-
Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria
-
Djimdé A., Doumbo O.K., Steketee R.W., and Plowe C.V. Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria. Lancet 358 (2001) 890-891
-
(2001)
Lancet
, vol.358
, pp. 890-891
-
-
Djimdé, A.1
Doumbo, O.K.2
Steketee, R.W.3
Plowe, C.V.4
-
7
-
-
10744233894
-
Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria
-
Djimdé A.A., Doumbo O.K., Traore O., Guindo A.B., Kayentao K., Diourte Y., Niare-Doumbo S., Coulibaly D., Kone A.K., Cissoko Y., Tekete M., Fofana B., Dicko A., Diallo D.A., Wellems T.E., Kwiatkowski D., and Plowe C.V. Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria. Am. J. Trop. Med. Hyg. 69 (2003) 558-563
-
(2003)
Am. J. Trop. Med. Hyg.
, vol.69
, pp. 558-563
-
-
Djimdé, A.A.1
Doumbo, O.K.2
Traore, O.3
Guindo, A.B.4
Kayentao, K.5
Diourte, Y.6
Niare-Doumbo, S.7
Coulibaly, D.8
Kone, A.K.9
Cissoko, Y.10
Tekete, M.11
Fofana, B.12
Dicko, A.13
Diallo, D.A.14
Wellems, T.E.15
Kwiatkowski, D.16
Plowe, C.V.17
-
8
-
-
0035341936
-
Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda
-
Dorsey G., Kamya M.R., Singh A., and Rosenthal P.J. Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda. J. Infect. Dis. 183 (2001) 1417-1420
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 1417-1420
-
-
Dorsey, G.1
Kamya, M.R.2
Singh, A.3
Rosenthal, P.J.4
-
9
-
-
0033636607
-
Mutations in the P. falciparum digestive vacuole transmembrane protein pfcrt and evidence for their role in chloroquine resistance
-
Fidock D.A., Nomura T., Talley A.K., Cooper R.A., Dzekunov S.M., Ferdig M.T., Ursos L.M.B., Sidhu A., Naude B., Deitsch K.W., Su X., Wootton J.C., Roepe P.D., and Wellems T.E. Mutations in the P. falciparum digestive vacuole transmembrane protein pfcrt and evidence for their role in chloroquine resistance. Mol. Cell. 6 (2000) 861-871
-
(2000)
Mol. Cell.
, vol.6
, pp. 861-871
-
-
Fidock, D.A.1
Nomura, T.2
Talley, A.K.3
Cooper, R.A.4
Dzekunov, S.M.5
Ferdig, M.T.6
Ursos, L.M.B.7
Sidhu, A.8
Naude, B.9
Deitsch, K.W.10
Su, X.11
Wootton, J.C.12
Roepe, P.D.13
Wellems, T.E.14
-
10
-
-
0025263958
-
Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance
-
Foote S.J., Galatis D., and Cowman A.F. Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 3014-3017
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 3014-3017
-
-
Foote, S.J.1
Galatis, D.2
Cowman, A.F.3
-
11
-
-
0028266982
-
The mode of action and the mechanism of resistance to antimalarial drugs
-
Foote S.J., and Cowman A.F. The mode of action and the mechanism of resistance to antimalarial drugs. Acta. Trop. 56 (1994) 157-171
-
(1994)
Acta. Trop.
, vol.56
, pp. 157-171
-
-
Foote, S.J.1
Cowman, A.F.2
-
12
-
-
0347285290
-
-
International Artemisinin Study Group, 2004. Artesunate combinations for treatment of malaria: meta-analysis. Lancet 363, 9-17.
-
-
-
-
13
-
-
0032580723
-
Molecular assays for surveillance of antifolate-resistant malaria
-
Kublin J.G., Witzig R.S., Shankar A.H., Zurita J.Q., Gilman R.H., Guarda J.A., Cortese J.F., and Plowe C.V. Molecular assays for surveillance of antifolate-resistant malaria. Lancet 351 (1998) 1629-1630
-
(1998)
Lancet
, vol.351
, pp. 1629-1630
-
-
Kublin, J.G.1
Witzig, R.S.2
Shankar, A.H.3
Zurita, J.Q.4
Gilman, R.H.5
Guarda, J.A.6
Cortese, J.F.7
Plowe, C.V.8
-
14
-
-
0036467612
-
Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria
-
Kublin J.G., Dzinjalamala F.K., Kamwendo D.D., Malkin E.M., Cortese J.F., Martino L.M., Mukadam R.A., Rogerson S.J., Lescano A.G., Molyneux M.E., Winstanley P.A., Chimpeni P., Taylor T.E., and Plowe C.V. Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria. J. Infect. Dis. 185 (2002) 380-388
-
(2002)
J. Infect. Dis.
, vol.185
, pp. 380-388
-
-
Kublin, J.G.1
Dzinjalamala, F.K.2
Kamwendo, D.D.3
Malkin, E.M.4
Cortese, J.F.5
Martino, L.M.6
Mukadam, R.A.7
Rogerson, S.J.8
Lescano, A.G.9
Molyneux, M.E.10
Winstanley, P.A.11
Chimpeni, P.12
Taylor, T.E.13
Plowe, C.V.14
-
15
-
-
0038239207
-
Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi
-
Kublin J.G., Cortese J.F., Njunju E.M., Mukadam R.A.G., Wirima J.J., Kazembe P.N., Djimdé A.A., Kouriba B., Taylor T.E., and Plowe C.V. Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi. J. Infect. Dis. 187 (2003) 1870-1875
-
(2003)
J. Infect. Dis.
, vol.187
, pp. 1870-1875
-
-
Kublin, J.G.1
Cortese, J.F.2
Njunju, E.M.3
Mukadam, R.A.G.4
Wirima, J.J.5
Kazembe, P.N.6
Djimdé, A.A.7
Kouriba, B.8
Taylor, T.E.9
Plowe, C.V.10
-
16
-
-
33750730913
-
Return of chloroquine antimalarial efficacy in Malawi
-
Laufer M.K., Thesing P.C., Eddington N.D., Masonga R., Dzinjalamala F.K., Takala S.L., Taylor T.E., and Plowe C.V. Return of chloroquine antimalarial efficacy in Malawi. N. Engl. J. Med. 355 (2006) 1959-1966
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1959-1966
-
-
Laufer, M.K.1
Thesing, P.C.2
Eddington, N.D.3
Masonga, R.4
Dzinjalamala, F.K.5
Takala, S.L.6
Taylor, T.E.7
Plowe, C.V.8
-
17
-
-
0035341841
-
Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique
-
Mayor A.G., Gomez-Olive X., Aponte J.J., Casimiro S., Mabunda S., Dgedge M., Barreto A., and Alonso P.L. Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique. J. Infect. Dis. 183 (2001) 1413-1416
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 1413-1416
-
-
Mayor, A.G.1
Gomez-Olive, X.2
Aponte, J.J.3
Casimiro, S.4
Mabunda, S.5
Dgedge, M.6
Barreto, A.7
Alonso, P.L.8
-
18
-
-
0034065697
-
Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites
-
Nzila A.M., Mberu E.K., Sulo J., Dayo H., Winstanley P.A., Sibley C.H., and Watkins W.M. Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. Antimicrob. Agents. Chemother. 44 (2000) 991-996
-
(2000)
Antimicrob. Agents. Chemother.
, vol.44
, pp. 991-996
-
-
Nzila, A.M.1
Mberu, E.K.2
Sulo, J.3
Dayo, H.4
Winstanley, P.A.5
Sibley, C.H.6
Watkins, W.M.7
-
19
-
-
3042595929
-
Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa
-
Ochong E., Nzila A., Kimani S., Kokwaro G., Mutabingwa T., Watkins W., and Marsh K. Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa. Malar J. 2 (2003) 46
-
(2003)
Malar J.
, vol.2
, pp. 46
-
-
Ochong, E.1
Nzila, A.2
Kimani, S.3
Kokwaro, G.4
Mutabingwa, T.5
Watkins, W.6
Marsh, K.7
-
20
-
-
0000841123
-
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria
-
Peterson D.S., Walliker D., and Wellems T.E. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 9114-9118
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 9114-9118
-
-
Peterson, D.S.1
Walliker, D.2
Wellems, T.E.3
-
21
-
-
0029050608
-
Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa
-
Plowe C.V., Djimdé A., Bouare M., Doumbo O., and Wellems T.E. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. Am. J. Trop. Med. Hyg. 52 (1995) 565-568
-
(1995)
Am. J. Trop. Med. Hyg.
, vol.52
, pp. 565-568
-
-
Plowe, C.V.1
Djimdé, A.2
Bouare, M.3
Doumbo, O.4
Wellems, T.E.5
-
22
-
-
0030720799
-
Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance
-
Plowe C.V., Cortese J.F., Djimdé A., Nwanyanwu O.C., Watkins W.M., Winstanley P.A., Estrada-Franco J.G., Mollinedo R.E., Avila J.C., Cespedes J.L., Carter D., and Doumbo O.K. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance. J. Infect. Dis. 176 (1997) 1590-1596
-
(1997)
J. Infect. Dis.
, vol.176
, pp. 1590-1596
-
-
Plowe, C.V.1
Cortese, J.F.2
Djimdé, A.3
Nwanyanwu, O.C.4
Watkins, W.M.5
Winstanley, P.A.6
Estrada-Franco, J.G.7
Mollinedo, R.E.8
Avila, J.C.9
Cespedes, J.L.10
Carter, D.11
Doumbo, O.K.12
-
23
-
-
1542283603
-
Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study
-
Plowe C.V., Kublin J.G., Dzinjalamala F.K., Kamwendo D.S., Mukadam R.A.G., Chimpeni P., Molyneux M.E., and Taylor T.E. Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study. BMJ 328 (2004) 545-548
-
(2004)
BMJ
, vol.328
, pp. 545-548
-
-
Plowe, C.V.1
Kublin, J.G.2
Dzinjalamala, F.K.3
Kamwendo, D.S.4
Mukadam, R.A.G.5
Chimpeni, P.6
Molyneux, M.E.7
Taylor, T.E.8
-
24
-
-
0035702490
-
Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?
-
Sibley C.H., Hyde J.E., Sims P.F., Plowe C.V., Kublin J.G., Mberu E.K., Cowman A.F., Winstanley P.A., Watkins W.M., and Nzila A.M. Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?. Trends Parasitol. 17 (2001) 582-588
-
(2001)
Trends Parasitol.
, vol.17
, pp. 582-588
-
-
Sibley, C.H.1
Hyde, J.E.2
Sims, P.F.3
Plowe, C.V.4
Kublin, J.G.5
Mberu, E.K.6
Cowman, A.F.7
Winstanley, P.A.8
Watkins, W.M.9
Nzila, A.M.10
-
25
-
-
0037020024
-
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations
-
Sidhu A.B.S., Verdier-Pinard D., and Fidock D.A. Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science 298 (2002) 210-213
-
(2002)
Science
, vol.298
, pp. 210-213
-
-
Sidhu, A.B.S.1
Verdier-Pinard, D.2
Fidock, D.A.3
-
26
-
-
2442686477
-
Relationship between age, molecular markers, and response to sulphadoxine-pyrimethamine treatment in Kampala, Uganda
-
Staedke S.G., Sendagire H., Lamola S., Kamya M.R., Dorsey G., and Rosenthal P. Relationship between age, molecular markers, and response to sulphadoxine-pyrimethamine treatment in Kampala, Uganda. Trop. Med. Int. Health 9 (2004) 624-629
-
(2004)
Trop. Med. Int. Health
, vol.9
, pp. 624-629
-
-
Staedke, S.G.1
Sendagire, H.2
Lamola, S.3
Kamya, M.R.4
Dorsey, G.5
Rosenthal, P.6
-
27
-
-
0030801206
-
Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins
-
Wang P., Lee C.S., Bayoumi R., Djimdé A., Doumbo O., Swedberg G., Dao L.D., Mshinda H., Tanner M., Watkins W.M., Sims P.F., and Hyde J.E. Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins. Mol. Biochem. Parasitol. 89 (1997) 161-177
-
(1997)
Mol. Biochem. Parasitol.
, vol.89
, pp. 161-177
-
-
Wang, P.1
Lee, C.S.2
Bayoumi, R.3
Djimdé, A.4
Doumbo, O.5
Swedberg, G.6
Dao, L.D.7
Mshinda, H.8
Tanner, M.9
Watkins, W.M.10
Sims, P.F.11
Hyde, J.E.12
-
28
-
-
0031029877
-
Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization
-
Wang P., Read M., Sims P.F., and Hyde J.E. Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization. Mol. Microbiol. 23 (1997) 979-986
-
(1997)
Mol. Microbiol.
, vol.23
, pp. 979-986
-
-
Wang, P.1
Read, M.2
Sims, P.F.3
Hyde, J.E.4
-
29
-
-
0030813699
-
The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses
-
Watkins W.M., Mberu E.K., Winstanley P.A., and Plowe C.V. The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses. Parasitol. Today 13 (1997) 459-464
-
(1997)
Parasitol. Today
, vol.13
, pp. 459-464
-
-
Watkins, W.M.1
Mberu, E.K.2
Winstanley, P.A.3
Plowe, C.V.4
-
30
-
-
34250187587
-
-
World Health Organization 2003. Assessment and monitoring of antimalarial drug efficacy for the treatment of uncomplicated falciparum malaria. WHO/HTM/RBM/2003.50.
-
-
-
|