-
1
-
-
78449269612
-
Molecular motors in neurons: Transport mechanisms and roles in brain function, development, and disease
-
Hirokawa, N., Niwa, S. & Tanaka, Y. Molecular motors in neurons: Transport mechanisms and roles in brain function, development, and disease. Neuron 68, 610-638 (2010).
-
(2010)
Neuron
, vol.68
, pp. 610-638
-
-
Hirokawa, N.1
Niwa, S.2
Tanaka, Y.3
-
2
-
-
70349437416
-
Kinesin superfamily motor proteins and intracellular transport
-
Hirokawa, N., Noda, Y., Tanaka, Y. & Niwa, S. Kinesin superfamily motor proteins and intracellular transport. Nature Rev. Mol. Cell Biol. 10, 682-696 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol
, vol.10
, pp. 682-696
-
-
Hirokawa, N.1
Noda, Y.2
Tanaka, Y.3
Niwa, S.4
-
3
-
-
0030933293
-
Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro
-
Rogers, S. L., Tint, I. S., Fanapour, P. C. & Gelfand, V. I. Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro. Proc. Natl Acad. Sci. USA 94, 3720-3725 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 3720-3725
-
-
Rogers, S.L.1
Tint, I.S.2
Fanapour, P.C.3
Gelfand, V.I.4
-
4
-
-
0037018150
-
Interactions and regulation of molecular motors in xenopus melanophores
-
Gross, S. P. et al. Interactions and regulation of molecular motors in Xenopus melanophores. J. Cell Biol. 156, 855-865 (2002).
-
(2002)
J. Cell Biol
, vol.156
, pp. 855-865
-
-
Gross, S.P.1
-
5
-
-
0036538577
-
Cytoplasmic dynein associated structures move bidirectionally in vivo
-
Ma, S. & Chisholm, R. L. Cytoplasmic dynein associated structures move bidirectionally in vivo. J. Cell Sci. 115, 1453-1460 (2002).
-
(2002)
J. Cell Sci
, vol.115
, pp. 1453-1460
-
-
Ma, S.1
Chisholm, R.L.2
-
6
-
-
2342640469
-
A direct interaction between cytoplasmic dynein and kinesin i may coordinate motor activity
-
Ligon, L. A., Tokito, M., Finklestein, J. M., Grossman, F. E. & Holzbaur, E. L. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. J. Biol. Chem. 279, 19201-19208 (2004
-
(2004)
J. Biol. Chem
, vol.279
, pp. 19201-19208
-
-
Ligon, L.A.1
Tokito, M.2
Finklestein, J.M.3
Grossman, F.E.4
Holzbaur, E.L.5
-
7
-
-
77951206786
-
Motor coordination via a tug of war mechanism drives bidirectional vesicle transport
-
Hendricks, A. G. et al. Motor coordination via a tug of war mechanism drives bidirectional vesicle transport. Curr. Biol. 20, 697-702 (2010).
-
(2010)
Curr. Biol
, vol.20
, pp. 697-702
-
-
Hendricks, A.G.1
-
8
-
-
79951710366
-
Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles
-
Encalada, S. E., Szpankowski, L., Xia, C. H. & Goldstein, L. S. Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell 144, 551-565 (2011).
-
(2011)
Cell
, vol.144
, pp. 551-565
-
-
Encalada, S.E.1
Szpankowski, L.2
Xia, C.H.3
Goldstein, L.S.4
-
9
-
-
84873279659
-
Trak/milton motor-Adaptor proteins steer mitochondrial trafficking to axons and dendrites
-
van Spronsen, M. et al. TRAK/Milton motor-Adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron 77, 485-502 (2013).
-
(2013)
Neuron
, vol.77
, pp. 485-502
-
-
Van Spronsen, M.1
-
10
-
-
0037447054
-
Dynactin: Coordinating motors with opposite inclinations
-
Gross, S. P. Dynactin: Coordinating motors with opposite inclinations. Curr. Biol. 13, R320-R322 (2003).
-
(2003)
Curr. Biol
, vol.13
-
-
Gross, S.P.1
-
11
-
-
3142642871
-
Bidirectional transport along microtubules
-
Welte, M. A. Bidirectional transport along microtubules. Curr. Biol. 14, R525-R537 (2004).
-
(2004)
Curr. Biol
, vol.14
-
-
Welte, M.A.1
-
12
-
-
75749098711
-
Opposite-polarity motors activate one another to trigger cargo transport in live cells
-
Ally, S., Larson, A. G., Barlan, K., Rice, S. E. & Gelfand, V. I. Opposite-polarity motors activate one another to trigger cargo transport in live cells. J. Cell Biol. 187, 1071-1082 (2009).
-
(2009)
J. Cell Biol
, vol.187
, pp. 1071-1082
-
-
Ally, S.1
Larson, A.G.2
Barlan, K.3
Rice, S.E.4
Gelfand, V.I.5
-
13
-
-
48249102303
-
Role of axonal transport in neurodegenerative diseases
-
De Vos, K. J., Grierson, A. J., Ackerley, S. & Miller, C. C. Role of axonal transport in neurodegenerative diseases. Annu. Rev. Neurosci. 31, 151-173 (2008).
-
(2008)
Annu. Rev. Neurosci
, vol.31
, pp. 151-173
-
-
De Vos, K.J.1
Grierson, A.J.2
Ackerley, S.3
Miller, C.C.4
-
15
-
-
78650545423
-
Deficits in axonal transport precede ALS symptoms in vivo
-
Bilsland, L. G. et al. Deficits in axonal transport precede ALS symptoms in vivo. Proc. Natl Acad. Sci. USA 107, 20523-20528 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 20523-20528
-
-
Bilsland, L.G.1
-
16
-
-
67649826155
-
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
-
Morfini, G. A. et al. Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nature Neurosci. 12, 864-871 (2009).
-
(2009)
Nature Neurosci
, vol.12
, pp. 864-871
-
-
Morfini, G.A.1
-
17
-
-
50849083264
-
Retrograde axonal transport and motor neuron disease
-
Strom, A. L. et al. Retrograde axonal transport and motor neuron disease. J. Neurochem. 106, 495-505 (2008).
-
(2008)
J. Neurochem
, vol.106
, pp. 495-505
-
-
Strom, A.L.1
-
18
-
-
68549121208
-
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration
-
Perlson, E. et al. A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. J. Neurosci. 29, 9903-9917 (2009).
-
(2009)
J. Neurosci
, vol.29
, pp. 9903-9917
-
-
Perlson, E.1
-
19
-
-
9244243320
-
Hither and yon: A review of bi directional microtubule-based transport
-
Gross, S. P. Hither and yon: A review of bi directional microtubule-based transport. Phys. Biol. 1, R1-R11 (2004).
-
(2004)
Phys. Biol
, vol.1
-
-
Gross, S.P.1
-
20
-
-
30544452263
-
The axonal transport of mitochondria
-
Hollenbeck, P. J. & Saxton, W. M. The axonal transport of mitochondria. J. Cell Sci. 118, 5411-5419 (2005).
-
(2005)
J. Cell Sci
, vol.118
, pp. 5411-5419
-
-
Hollenbeck, P.J.1
Saxton, W.M.2
-
21
-
-
33845315084
-
Powering membrane traffic in endocytosis and recycling
-
Soldati, T. & Schliwa, M. Powering membrane traffic in endocytosis and recycling. Nature Rev. Mol. Cell Biol. 7, 897-908 (2006).
-
(2006)
Nature Rev. Mol. Cell Biol
, vol.7
, pp. 897-908
-
-
Soldati, T.1
Schliwa, M.2
-
22
-
-
84862870271
-
The axonal transport of mitochondria
-
Saxton, W. M. & Hollenbeck, P. J. The axonal transport of mitochondria. J. Cell Sci. 125, 2095-2104 (2012).
-
(2012)
J. Cell Sci
, vol.125
, pp. 2095-2104
-
-
Saxton, W.M.1
Hollenbeck, P.J.2
-
23
-
-
70350169763
-
Fat on the move: Intracellular motion of lipid droplets
-
Welte, M. A. Fat on the move: Intracellular motion of lipid droplets. Biochem. Soc. Trans. 37, 991-996 (2009).
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 991-996
-
-
Welte, M.A.1
-
24
-
-
84899134578
-
Axon and dendritic trafficking
-
Maeder, C. I., Shen, K. & Hoogenraad, C. C. Axon and dendritic trafficking. Curr. Opin. Neurobiol. 27C, 165-170 (2014).
-
(2014)
Curr. Opin. Neurobiol
, vol.27 C
, pp. 165-170
-
-
Maeder, C.I.1
Shen, K.2
Hoogenraad, C.C.3
-
25
-
-
0033712055
-
Kinesin-dependent axonal transport is mediated by the sunday driver (syd) protein
-
Bowman, A. B. et al. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell 103, 583-594 (2000).
-
(2000)
Cell
, vol.103
, pp. 583-594
-
-
Bowman, A.B.1
-
26
-
-
0034672280
-
Isolation and characterization of substance P containing dense core vesicles from rabbit optic nerve and termini
-
Berg, E. A. et al. Isolation and characterization of substance P containing dense core vesicles from rabbit optic nerve and termini. J. Neurosci. Res. 62, 830-839 (2000).
-
(2000)
J. Neurosci. Res
, vol.62
, pp. 830-839
-
-
Berg, E.A.1
-
27
-
-
38749141397
-
Identification of an axonal kinesin 3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides
-
Barkus, R. V., Klyachko, O., Horiuchi, D., Dickson, B. J. & Saxton, W. M. Identification of an axonal kinesin 3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. Mol. Biol. Cell 19, 274-283 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 274-283
-
-
Barkus, R.V.1
Klyachko, O.2
Horiuchi, D.3
Dickson, B.J.4
Saxton, W.M.5
-
28
-
-
83455229793
-
Arl8 and SKIP act together to link lysosomes to kinesin 1
-
Rosa-Ferreira, C. & Munro, S. Arl8 and SKIP act together to link lysosomes to kinesin 1. Dev. Cell 21, 1171-1178 (2011).
-
(2011)
Dev Cell
, vol.21
, pp. 1171-1178
-
-
Rosa-Ferreira, C.1
Munro, S.2
-
29
-
-
84857858536
-
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
-
Maday, S., Wallace, K. E. & Holzbaur, E. L. Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J. Cell Biol. 196, 407-417 (2012).
-
(2012)
J. Cell Biol
, vol.196
, pp. 407-417
-
-
Maday, S.1
Wallace, K.E.2
Holzbaur, E.L.3
-
30
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin i
-
Kamal, A., Stokin, G B., Yang, Z., Xia, C. H. & Goldstein, L. S. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin I. Neuron 28, 449-459 (2000).
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
31
-
-
84881189138
-
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
-
Fu, M. M. & Holzbaur, E. L. JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. J. Cell Biol. 202, 495-508 (2013).
-
(2013)
J. Cell Biol
, vol.202
, pp. 495-508
-
-
Fu, M.M.1
Holzbaur, E.L.2
-
32
-
-
84894431292
-
UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport
-
Almenar-Queralt, A. et al. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J. Neurosci. 34, 3320-3339 (2014).
-
(2014)
J. Neurosci
, vol.34
, pp. 3320-3339
-
-
Almenar-Queralt, A.1
-
33
-
-
0037415607
-
Dynactin is required for bidirectional organelle transport
-
Deacon, S. W. et al. Dynactin is required for bidirectional organelle transport. J. Cell Biol. 160, 297-301 (2003).
-
(2003)
J. Cell Biol
, vol.160
, pp. 297-301
-
-
Deacon, S.W.1
-
34
-
-
33644548583
-
Organelle transport along microtubules in Xenopus melanophores: Evidence for cooperation between multiple motors
-
Levi, V., Serpinskaya, A. S., Gratton, E. & Gelfand, V. Organelle transport along microtubules in Xenopus melanophores: Evidence for cooperation between multiple motors. Biophys. J. 90, 318-327 (2006).
-
(2006)
Biophys. J.
, vol.90
, pp. 318-327
-
-
Levi, V.1
Serpinskaya, A.S.2
Gratton, E.3
Gelfand, V.4
-
35
-
-
0031875170
-
Regulation of organelle movement in melanophores by protein kinase a (pka), protein kinase c (pkc), and protein phosphatase 2a (pp2a)
-
Reilein, A. R., Tint, I. S., Peunova, N. I., Enikolopov, G. N. & Gelfand, V. I. Regulation of organelle movement in melanophores by protein kinase A (PKA), protein kinase C (PKC), and protein phosphatase 2A (PP2A). J. Cell Biol. 142, 803-813 (1998).
-
(1998)
J. Cell Biol
, vol.142
, pp. 803-813
-
-
Reilein, A.R.1
Tint, I.S.2
Peunova, N.I.3
Enikolopov, G.N.4
Gelfand, V.I.5
-
36
-
-
0032576778
-
Myosin cooperates with microtubule motors during organelle transport in melanophores
-
Rogers, S. L. & Gelfand, V. I. Myosin cooperates with microtubule motors during organelle transport in melanophores. Curr. Biol. 8, 161-164 (1998).
-
(1998)
Curr. Biol
, vol.8
, pp. 161-164
-
-
Rogers, S.L.1
Gelfand, V.I.2
-
37
-
-
0033588979
-
Regulation of melanosome movement in the cell cycle by reversible association with myosin v
-
Rogers, S. L. et al. Regulation of melanosome movement in the cell cycle by reversible association with myosin V. J. Cell Biol. 146, 1265-1276 (1999).
-
(1999)
J Cell Biol
, vol.146
, pp. 1265-1276
-
-
Rogers, S.L.1
-
38
-
-
0031615460
-
In vitro motility assay for melanophore pigment organelles
-
Rogers, S. L., Tint, I. S. & Gelfand, V. I. In vitro motility assay for melanophore pigment organelles. Methods Enzymol. 298, 361-372 (1998).
-
(1998)
Methods Enzymol
, vol.298
, pp. 361-372
-
-
Rogers, S.L.1
Tint, I.S.2
Gelfand, V.I.3
-
39
-
-
0032517764
-
Heterotrimeric kinesin II is the microtubule motor protein responsible for pigment dispersion in Xenopus melanophores
-
Tuma, M. C., Zill, A., Le Bot, N., Vernos, I. & Gelfand, V. Heterotrimeric kinesin II is the microtubule motor protein responsible for pigment dispersion in Xenopus melanophores. J. Cell Biol. 143, 1547-1558 (1998).
-
(1998)
J. Cell Biol
, vol.143
, pp. 1547-1558
-
-
Tuma, M.C.1
Zill, A.2
Le Bot, N.3
Vernos, I.4
Gelfand, V.5
-
40
-
-
20344382542
-
Kinesin and dynein move a peroxisome in vivo: A tug of war or coordinated movement
-
Kural, C et al. Kinesin and dynein move a peroxisome in vivo: A tug of war or coordinated movement? Science 308, 1469-1472 (2005).
-
(2005)
Science
, vol.308
, pp. 1469-1472
-
-
Kural, C.1
-
41
-
-
0032568790
-
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
-
Tanaka, Y. et al. Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell 93, 1147-1158 (1998).
-
(1998)
Cell
, vol.93
, pp. 1147-1158
-
-
Tanaka, Y.1
-
42
-
-
33646759268
-
Kinesin 1 and dynein are the primary motors for fast transport of mitochondria in drosophila motor axons
-
Pilling, A. D., Horiuchi, D., Lively, C. M. & Saxton, W. M. Kinesin 1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons. Mol. Biol. Cell 17, 2057-2068 (2006).
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2057-2068
-
-
Pilling, A.D.1
Horiuchi, D.2
Lively, C.M.3
Saxton, W.M.4
-
43
-
-
84871967163
-
Quantitative optical trapping on single organelles in cell extract
-
Barak, P., Rai, A., Rai, P. & Mallik, R. Quantitative optical trapping on single organelles in cell extract. Nature Methods 10, 68-70 (2013).
-
(2013)
Nature Methods
, vol.10
, pp. 68-70
-
-
Barak, P.1
Rai, A.2
Rai, P.3
Mallik, R.4
-
44
-
-
0141503438
-
A determinant for directionality of organelle transport in drosophila embryos
-
Gross, S. P., Guo, Y., Martinez, J. E. & Welte, M. A. A determinant for directionality of organelle transport in Drosophila embryos. Curr. Biol. 13, 1660-1668 (2003).
-
(2003)
Curr. Biol
, vol.13
, pp. 1660-1668
-
-
Gross, S.P.1
Guo, Y.2
Martinez, J.E.3
Welte, M.A.4
-
45
-
-
0034611001
-
Dynein-mediated cargo transport in vivo a switch controls travel distance
-
Gross, S. P., Welte, M. A., Block, S. M. & Wieschaus, E. F. Dynein-mediated cargo transport in vivo. A switch controls travel distance. J. Cell Biol. 148, 945-956 (2000).
-
(2000)
J. Cell Biol
, vol.148
, pp. 945-956
-
-
Gross, S.P.1
Welte, M.A.2
Block, S.M.3
Wieschaus, E.F.4
-
46
-
-
0037128208
-
Coordination of opposite-polarity microtubule motors
-
Gross, S. P., Welte, M. A., Block, S. M. & Wieschaus, E. F. Coordination of opposite-polarity microtubule motors. J. Cell Biol. 156, 715-724 (2002).
-
(2002)
J. Cell Biol
, vol.156
, pp. 715-724
-
-
Gross, S.P.1
Welte, M.A.2
Block, S.M.3
Wieschaus, E.F.4
-
47
-
-
57149145788
-
Consequences of motor copy number on the intracellular transport of kinesin 1 driven lipid droplets
-
Shubeita, G. T. et al. Consequences of motor copy number on the intracellular transport of kinesin 1 driven lipid droplets. Cell 135, 1098-1107 (2008).
-
(2008)
Cell
, vol.135
, pp. 1098-1107
-
-
Shubeita, G.T.1
-
48
-
-
0032548920
-
Developmental regulation of vesicle transport in Drosophila embryos: Forces and kinetics
-
Welte, M. A., Gross, S. P., Postner, M., Block, S. M. & Wieschaus, E. F. Developmental regulation of vesicle transport in Drosophila embryos: Forces and kinetics. Cell 92, 547-557 (1998).
-
(1998)
Cell
, vol.92
, pp. 547-557
-
-
Welte, M.A.1
Gross, S.P.2
Postner, M.3
Block, S.M.4
Wieschaus, E.F.5
-
49
-
-
22744434906
-
Regulation of lipid-droplet transport by the perilipin homolog LSD2
-
Welte, M. A. et al. Regulation of lipid-droplet transport by the perilipin homolog LSD2. Curr. Biol. 15, 1266-1275 (2005).
-
(2005)
Curr. Biol
, vol.15
, pp. 1266-1275
-
-
Welte, M.A.1
-
50
-
-
0027286361
-
A motility in the eukaryotic flagellum unrelated to flagellar beating
-
Kozminski, K. G., Johnson, K. A., Forscher, P. & Rosenbaum, J. L. A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc. Natl Acad. Sci. USA 90, 5519-5523 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 5519-5523
-
-
Kozminski, K.G.1
Johnson, K.A.2
Forscher, P.3
Rosenbaum, J.L.4
-
51
-
-
0032428685
-
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
-
Nonaka, S. et al. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95, 829-837 (1998).
-
(1998)
Cell
, vol.95
, pp. 829-837
-
-
Nonaka, S.1
-
52
-
-
0031750484
-
Chlamydomonas kinesin-II dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons
-
Cole, D. G. et al. Chlamydomonas kinesin-II dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J. Cell Biol. 141, 993-1008 (1998).
-
(1998)
J. Cell Biol
, vol.141
, pp. 993-1008
-
-
Cole, D.G.1
-
53
-
-
0031777851
-
A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT
-
Pazour, G. J., Wilkerson, C. G. & Witman, G. B. A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). J. Cell Biol. 141, 979-992 (1998).
-
(1998)
J. Cell Biol
, vol.141
, pp. 979-992
-
-
Pazour, G.J.1
Wilkerson, C.G.2
Witman, G.B.3
-
54
-
-
0034735526
-
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
-
Pazour, G. J. et al. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J. Cell Biol. 151, 709-718 (2000).
-
(2000)
J. Cell Biol
, vol.151
, pp. 709-718
-
-
Pazour, G.J.1
-
56
-
-
0035899865
-
Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles
-
Deane, J. A., Cole, D. G., Seeley, E. S., Diener, D. R. & Rosenbaum, J. L. Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. Curr. Biol. 11, 1586-1590 (2001).
-
(2001)
Curr. Biol
, vol.11
, pp. 1586-1590
-
-
Deane, J.A.1
Cole, D.G.2
Seeley, E.S.3
Diener, D.R.4
Rosenbaum, J.L.5
-
57
-
-
0037115599
-
Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells
-
Mikami, A. et al. Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells. J. Cell Sci. 115, 4801-4808 (2002).
-
(2002)
J. Cell Sci
, vol.115
, pp. 4801-4808
-
-
Mikami, A.1
-
59
-
-
33749024768
-
Mechanism of transport of IFT particles in C elegans cilia by the concerted action of kinesin II and OSM 3 motors
-
Pan, X. et al. Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin II and OSM 3 motors. J. Cell Biol. 174, 1035-1045 (2006).
-
(2006)
J. Cell Biol
, vol.174
, pp. 1035-1045
-
-
Pan, X.1
-
60
-
-
7944222301
-
Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C elegans neurons
-
Snow, J. J. et al. Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C. elegans neurons. Nature Cell Biol. 6, 1109-1113 (2004).
-
(2004)
Nature Cell Biol
, vol.6
, pp. 1109-1113
-
-
Snow, J.J.1
-
61
-
-
0035795413
-
Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases
-
Iomini, C., Babaev-Khaimov, V., Sassaroli, M. & Piperno, G. Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases. J. Cell Biol. 153, 13-24 (2001).
-
(2001)
J. Cell Biol
, vol.153
, pp. 13-24
-
-
Iomini, C.1
Babaev-Khaimov, V.2
Sassaroli, M.3
Piperno, G.4
-
62
-
-
0034306462
-
Force production by single kinesin motors
-
Schnitzer, M. J., Visscher, K. & Block, S. M. Force production by single kinesin motors. Nature Cell Biol. 2, 718-723 (2000).
-
(2000)
Nature Cell Biol
, vol.2
, pp. 718-723
-
-
Schnitzer, M.J.1
Visscher, K.2
Block, S.M.3
-
63
-
-
0037183926
-
Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization
-
Tomishige, M., Klopfenstein, D. R. & Vale, R. D. Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization. Science 297, 2263-2267 (2002).
-
(2002)
Science
, vol.297
, pp. 2263-2267
-
-
Tomishige, M.1
Klopfenstein, D.R.2
Vale, R.D.3
-
64
-
-
0041522803
-
Processivity of the single-headed kinesin KIF1A through biased binding to tubulin
-
Okada, Y., Higuchi, H. & Hirokawa, N. Processivity of the single-headed kinesin KIF1A through biased binding to tubulin. Nature 424, 574-577 (2003).
-
(2003)
Nature
, vol.424
, pp. 574-577
-
-
Okada, Y.1
Higuchi, H.2
Hirokawa, N.3
-
65
-
-
19644377414
-
Mechanics of the kinesin step
-
Carter, N. J. & Cross, R. A. Mechanics of the kinesin step. Nature 435, 308-312 (2005).
-
(2005)
Nature
, vol.435
, pp. 308-312
-
-
Carter, N.J.1
Cross, R.A.2
-
66
-
-
70350501513
-
Single molecule imaging reveals differences in microtubule track selection between Kinesin motors
-
Cai, D., McEwen, D. P., Martens, J. R., Meyhofer, E. & Verhey, K. J. Single molecule imaging reveals differences in microtubule track selection between Kinesin motors. PLoS Biol. 7, e1000216 (2009).
-
(2009)
PLoS Biol
, vol.7
-
-
Cai, D.1
McEwen, D.P.2
Martens, J.R.3
Meyhofer, E.4
Verhey, K.J.5
-
67
-
-
84863465158
-
Force-dependent detachment of kinesin 2 biases track switching at cytoskeletal filament intersections
-
Schroeder, H. W. et al. Force-dependent detachment of kinesin 2 biases track switching at cytoskeletal filament intersections. Biophys. J. 103, 48-58 (2012).
-
(2012)
Biophys. J.
, vol.103
, pp. 48-58
-
-
Schroeder, H.W.1
-
69
-
-
0029954709
-
Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport
-
Niclas, J., Allan, V. J. & Vale, R. D. Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport. J. Cell Biol. 133, 585-593 (1996).
-
(1996)
J. Cell Biol
, vol.133
, pp. 585-593
-
-
Niclas, J.1
Allan, V.J.2
Vale, R.D.3
-
70
-
-
0035120707
-
Regulation of molecular motor proteins
-
Reilein, A. R., Rogers, S. L., Tuma, M. C. & Gelfand, V. I. Regulation of molecular motor proteins. Int. Rev. Cytol. 204, 179-238 (2001).
-
(2001)
Int. Rev. Cytol
, vol.204
, pp. 179-238
-
-
Reilein, A.R.1
Rogers, S.L.2
Tuma, M.C.3
Gelfand, V.I.4
-
71
-
-
0036468983
-
Principles of cargo attachment to cytoplasmic motor proteins
-
Kamal, A. & Goldstein, L. S. Principles of cargo attachment to cytoplasmic motor proteins. Curr. Opin. Cell Biol. 14, 63-68 (2002).
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 63-68
-
-
Kamal, A.1
Goldstein, L.S.2
-
72
-
-
34249047067
-
Direct interaction of Gas11 with microtubules: Implications for the dynein regulatory complex
-
Bekker, J. M. et al. Direct interaction of Gas11 with microtubules: Implications for the dynein regulatory complex. Cell. Motil. Cytoskeleton 64, 461-473 (2007).
-
(2007)
Cell. Motil. Cytoskeleton
, vol.64
, pp. 461-473
-
-
Bekker, J.M.1
-
73
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
Dixit, R., Ross, J. L., Goldman, Y. E. & Holzbaur, E. L. Differential regulation of dynein and kinesin motor proteins by tau. Science 319, 1086-1089 (2008).
-
(2008)
Science
, vol.319
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.4
-
74
-
-
70450228589
-
Regulators of the cytoplasmic dynein motor
-
Kardon, J. R. & Vale, R. D. Regulators of the cytoplasmic dynein motor. Nature Rev. Mol. Cell Biol. 10, 854-865 (2009
-
(2009)
Nature Rev. Mol. Cell Biol
, vol.10
, pp. 854-865
-
-
Kardon, J.R.1
Vale, R.D.2
-
75
-
-
77951701022
-
Lis1 and nude induce a persistent dynein force-producing state
-
McKenney, R. J., Vershinin, M., Kunwar, A., Vallee, R. B. & Gross, S. P. LIS1 and NudE induce a persistent dynein force-producing state. Cell 141, 304-314 (2010).
-
(2010)
Cell
, vol.141
, pp. 304-314
-
-
McKenney, R.J.1
Vershinin, M.2
Kunwar, A.3
Vallee, R.B.4
Gross, S.P.5
-
76
-
-
73849148044
-
Functional interplay between lis1 nde1 and ndel1 in dynein-dependent organelle positioning
-
Lam, C., Vergnolle, M. A., Thorpe, L., Woodman, P. G. & Allan, V. J. Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning. J. Cell Sci. 123, 202-212 (2010).
-
(2010)
J. Cell Sci
, vol.123
, pp. 202-212
-
-
Lam, C.1
Vergnolle, M.A.2
Thorpe, L.3
Woodman, P.G.4
Allan, V.J.5
-
77
-
-
80155203800
-
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport
-
Yi, J. Y. et al. High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport. J. Cell Biol. 195, 193-201 (2011).
-
(2011)
J. Cell Biol
, vol.195
, pp. 193-201
-
-
Yi, J.Y.1
-
78
-
-
84870545667
-
She1 mediated inhibition of dynein motility along astral microtubules promotes polarized spindle movements
-
Markus, S. M., Kalutkiewicz, K. A. & Lee, W. L. She1 mediated inhibition of dynein motility along astral microtubules promotes polarized spindle movements. Curr. Biol. 22, 2221-2230 (2012).
-
(2012)
Curr. Biol
, vol.22
, pp. 2221-2230
-
-
Markus, S.M.1
Kalutkiewicz, K.A.2
Lee, W.L.3
-
79
-
-
84863740946
-
Lis1 is an initiation factor for dynein-driven organelle transport
-
Egan, M. J., Tan, K. & Reck-Peterson, S. L. Lis1 is an initiation factor for dynein-driven organelle transport. J. Cell Biol. 197, 971-982 (2012).
-
(2012)
J. Cell Biol
, vol.197
, pp. 971-982
-
-
Egan, M.J.1
Tan, K.2
Reck-Peterson, S.L.3
-
80
-
-
84865679752
-
Lis1 acts as a clutch between the atpase and microtubule-binding domains of the dynein motor
-
Huang, J., Roberts, A. J., Leschziner, A. E. & Reck Peterson, S. L. Lis1 acts as a "clutch" Between the ATPase and microtubule-binding domains of the dynein motor. Cell 150, 975-986 (2012).
-
(2012)
Cell
, vol.150
, pp. 975-986
-
-
Huang, J.1
Roberts, A.J.2
Leschziner, A.E.3
Reck Peterson, S.L.4
-
81
-
-
84964596705
-
Ndel1 derived peptides modulate bidirectional transport of injected beads in the squid giant axon
-
Segal, M. et al. Ndel1 derived peptides modulate bidirectional transport of injected beads in the squid giant axon. Biol. Open 1, 220-231 (2012).
-
(2012)
Biol. Open
, vol.1
, pp. 220-231
-
-
Segal, M.1
-
82
-
-
0028009012
-
Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle
-
Rieder, C. L. & Salmon, E. D. Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle. J. Cell Biol. 124, 223-233 (1994).
-
(1994)
J. Cell Biol
, vol.124
, pp. 223-233
-
-
Rieder, C.L.1
Salmon, E.D.2
-
83
-
-
0027070849
-
Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins
-
Vale, R. D., Malik, F. & Brown, D. Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins. J. Cell Biol. 119, 1589-1596 (1992).
-
(1992)
J. Cell Biol
, vol.119
, pp. 1589-1596
-
-
Vale, R.D.1
Malik, F.2
Brown, D.3
-
84
-
-
42449124179
-
Tug of war as a cooperative mechanism for bidirectional cargo transport by molecular motors
-
Müller, M. J., Klumpp, S. & Lipowsky, R. Tug of war as a cooperative mechanism for bidirectional cargo transport by molecular motors. Proc. Natl Acad. Sci. USA 105, 4609-4614 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4609-4614
-
-
Müller, M.J.1
Klumpp, S.2
Lipowsky, R.3
-
85
-
-
84868202079
-
Tug of war in motor protein ensembles revealed with a programmable DNA origami scaffold
-
Derr, N. D. et al. Tug of war in motor protein ensembles revealed with a programmable DNA origami scaffold. Science 338, 662-665 (2012).
-
(2012)
Science
, vol.338
, pp. 662-665
-
-
Derr, N.D.1
-
86
-
-
84856287541
-
Cooperative responses of multiple kinesins to variable and constant loads
-
Jamison, D. K., Driver, J. W. & Diehl, M. R. Cooperative responses of multiple kinesins to variable and constant loads. J. Biol. Chem. 287, 3357-3365 (2011).
-
(2011)
J. Biol. Chem
, vol.287
, pp. 3357-3365
-
-
Jamison, D.K.1
Driver, J.W.2
Diehl, M.R.3
-
87
-
-
78349232437
-
Two kinesins transport cargo primarily via the action of one motor: Implications for intracellular transport
-
Jamison, D. K., Driver, J. W., Rogers, A. R., Constantinou, P. E. & Diehl, M. R. Two kinesins transport cargo primarily via the action of one motor: Implications for intracellular transport. Biophys. J. 99, 2967-2977 (2010).
-
(2010)
Biophys. J.
, vol.99
, pp. 2967-2977
-
-
Jamison, D.K.1
Driver, J.W.2
Rogers, A.R.3
Constantinou, P.E.4
Diehl, M.R.5
-
88
-
-
28444447392
-
Cooperative cargo transport by several molecular motors
-
Klumpp, S. & Lipowsky, R. Cooperative cargo transport by several molecular motors. Proc. Natl Acad. Sci. USA 102, 17284-17289 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 17284-17289
-
-
Klumpp, S.1
Lipowsky, R.2
-
89
-
-
68849100714
-
Negative interference dominates collective transport of kinesin motors in the absence of load
-
Rogers, A. R., Driver, J. W., Constantinou, P. E., Kenneth Jamison, D. & Diehl, M. R. Negative interference dominates collective transport of kinesin motors in the absence of load. Phys. Chem. Chem. Phys. 11, 4882-4889 (2009).
-
(2009)
Phys. Chem. Chem. Phys
, vol.11
, pp. 4882-4889
-
-
Rogers, A.R.1
Driver, J.W.2
Constantinou, P.E.3
Kenneth Jamison, D.4
Diehl, M.R.5
-
90
-
-
73349125122
-
Tug of war between dissimilar teams of microtubule motors regulates transport and fission of endosomes
-
Soppina, V., Rai, A. K., Ramaiya, A. J., Barak, P. & Mallik, R. Tug of war between dissimilar teams of microtubule motors regulates transport and fission of endosomes. Proc. Natl Acad. Sci. USA 106, 19381-19386 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 19381-19386
-
-
Soppina, V.1
Rai, A.K.2
Ramaiya, A.J.3
Barak, P.4
Mallik, R.5
-
91
-
-
77952961423
-
Bidirectional transport by molecular motors: Enhanced processivity and response to external forces
-
Müller, M. J., Klumpp, S. & Lipowsky, R. Bidirectional transport by molecular motors: Enhanced processivity and response to external forces. Biophys. J. 98, 2610-2618 (2010).
-
(2010)
Biophys. J.
, vol.98
, pp. 2610-2618
-
-
Müller, M.J.1
Klumpp, S.2
Lipowsky, R.3
-
92
-
-
33645517251
-
Finite-particle tracking reveals submicroscopic-size changes of mitochondria during transport in mitral cell dendrites
-
Gennerich, A. & Schild, D. Finite-particle tracking reveals submicroscopic-size changes of mitochondria during transport in mitral cell dendrites. Phys. Biol. 3, 45-53 (2006).
-
(2006)
Phys. Biol
, vol.3
, pp. 45-53
-
-
Gennerich, A.1
Schild, D.2
-
93
-
-
84874485595
-
In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport
-
Blehm, B. H., Schroer, T. A., Trybus, K. M., Chemla, Y. R. & Selvin, P. R. In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport. Proc. Natl Acad. Sci. USA 110, 3381-3386 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 3381-3386
-
-
Blehm, B.H.1
Schroer, T.A.2
Trybus, K.M.3
Chemla, Y.R.4
Selvin, P.R.5
-
94
-
-
0018101150
-
Models for the specific adhesion of cells to cells
-
Bell, G. I. Models for the specific adhesion of cells to cells. Science 200, 618-627 (1978).
-
(1978)
Science
, vol.200
, pp. 618-627
-
-
Bell, G.I.1
-
95
-
-
0034979287
-
Probing the relation between force-lifetime-And chemistry in single molecular bonds
-
Evans, E. Probing the relation between force-lifetime-And chemistry in single molecular bonds. Annu. Rev. Biophys. Biomol. Struct. 30, 105-128 (2001).
-
(2001)
Annu. Rev. Biophys. Biomol. Struct
, vol.30
, pp. 105-128
-
-
Evans, E.1
-
96
-
-
82755197371
-
Mechanical stochastic tug of war models cannot explain bidirectional lipid-droplet transport
-
Kunwar, A. et al. Mechanical stochastic tug of war models cannot explain bidirectional lipid-droplet transport. Proc. Natl Acad. Sci. USA 108, 18960-18965 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 18960-18965
-
-
Kunwar, A.1
-
97
-
-
84872506411
-
Molecular adaptations allow dynein to generate large collective forces inside cells
-
Rai, A. K., Rai, A., Ramaiya, A. J., Jha, R. & Mallik, R. Molecular adaptations allow dynein to generate large collective forces inside cells. Cell 152, 172-182 (2013).
-
(2013)
Cell
, vol.152
, pp. 172-182
-
-
Rai, A.K.1
Rai, A.2
Ramaiya, A.J.3
Jha, R.4
Mallik, R.5
-
98
-
-
0030744142
-
Kinesin hydrolyses one ATP per 8 nm step
-
Schnitzer, M. J. & Block, S. M. Kinesin hydrolyses one ATP per 8 nm step. Nature 388, 386-390 (1997).
-
(1997)
Nature
, vol.388
, pp. 386-390
-
-
Schnitzer, M.J.1
Block, S.M.2
-
99
-
-
72449205071
-
The mechanochemistry of integrated motor protein complexes
-
Constantinou, P. E. & Diehl, M. R. The mechanochemistry of integrated motor protein complexes. J. Biomech. 43, 31-37 (2010).
-
(2010)
J. Biomech
, vol.43
, pp. 31-37
-
-
Constantinou, P.E.1
Diehl, M.R.2
-
100
-
-
80052447606
-
Productive cooperation among processive motors depends inversely on their mechanochemical efficiency
-
Driver, J. W. et al. Productive cooperation among processive motors depends inversely on their mechanochemical efficiency. Biophys. J. 101, 386-395 (2011).
-
(2011)
Biophys. J.
, vol.101
, pp. 386-395
-
-
Driver, J.W.1
-
101
-
-
77957977698
-
Coupling between motor proteins determines dynamic behaviors of motor protein assemblies
-
Driver, J. W. et al. Coupling between motor proteins determines dynamic behaviors of motor protein assemblies. Phys. Chem. Chem. Phys. 12, 10398-10405 (2010).
-
(2010)
Phys. Chem. Chem. Phys
, vol.12
, pp. 10398-10405
-
-
Driver, J.W.1
-
102
-
-
77949858821
-
Robust transport by multiple motors with nonlinear force-velocity relations and stochastic load sharing
-
Kunwar, A. & Mogilner, A. Robust transport by multiple motors with nonlinear force-velocity relations and stochastic load sharing. Phys. Biol. 7, 16012 (2010).
-
(2010)
Phys. Biol
, vol.7
, pp. 16012
-
-
Kunwar, A.1
Mogilner, A.2
-
103
-
-
49649099173
-
Stepping strain gating, and an unexpected force-velocity curve for multiple-motor-based transport
-
Kunwar, A., Vershinin, M., Xu, J. & Gross, S. P. Stepping, strain gating, and an unexpected force-velocity curve for multiple-motor-based transport. Curr. Biol. 18, 1173-1183 (2008).
-
(2008)
Curr. Biol
, vol.18
, pp. 1173-1183
-
-
Kunwar, A.1
Vershinin, M.2
Xu, J.3
Gross, S.P.4
-
104
-
-
84886750648
-
Teamwork in microtubule motors
-
Mallik, R., Rai, A. K., Barak, P., Rai, A. & Kunwar, A. Teamwork in microtubule motors. Trends Cell Biol. 23, 575-582 (2013).
-
(2013)
Trends Cell Biol
, vol.23
, pp. 575-582
-
-
Mallik, R.1
Rai, A.K.2
Barak, P.3
Rai, A.4
Kunwar, A.5
-
105
-
-
84860372407
-
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila
-
Reis, G. F. et al. Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol. Biol. Cell 23, 1700-1714 (2012).
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1700-1714
-
-
Reis, G.F.1
-
106
-
-
84860272533
-
Dynactin is required for transport initiation from the distal axon
-
Moughamian, A. J. & Holzbaur, E. L. Dynactin is required for transport initiation from the distal axon. Neuron 74, 331-343 (2012).
-
(2012)
Neuron
, vol.74
, pp. 331-343
-
-
Moughamian, A.J.1
Holzbaur, E.L.2
-
107
-
-
77958194312
-
Probing intracellular motor protein activity using an inducible cargo trafficking assay
-
Kapitein, L. C. et al. Probing intracellular motor protein activity using an inducible cargo trafficking assay. Biophys. J. 99, 2143-2152 (2010).
-
(2010)
Biophys. J.
, vol.99
, pp. 2143-2152
-
-
Kapitein, L.C.1
-
108
-
-
79951835447
-
Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes
-
Caviston, J. P., Zajac, A. L., Tokito, M. & Holzbaur, E. L. Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes. Mol. Biol. Cell 22, 478-492 (2011).
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 478-492
-
-
Caviston, J.P.1
Zajac, A.L.2
Tokito, M.3
Holzbaur, E.L.4
-
109
-
-
0020170121
-
Microinjection into an identified axon to study the mechanism of fast axonal transport
-
Goldberg, D. J. Microinjection into an identified axon to study the mechanism of fast axonal transport. Proc. Natl Acad. Sci. USA 79, 4818-4822 (1982).
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 4818-4822
-
-
Goldberg, D.J.1
-
110
-
-
0025794072
-
Kinesin interactions with membrane bounded organelles in vivo and in vitro
-
Brady, S. T. & Pfister, K. K. Kinesin interactions with membrane bounded organelles in vivo and in vitro. J. Cell Sci. Suppl. 14, 103-108 (1991).
-
(1991)
J. Cell Sci. Suppl
, vol.14
, pp. 103-108
-
-
Brady, S.T.1
Pfister, K.K.2
-
111
-
-
0030716506
-
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
-
Waterman-Storer, C. M. et al. The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proc. Natl Acad. Sci. USA 94, 12180-12185 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 12180-12185
-
-
Waterman-Storer, C.M.1
-
112
-
-
0032741064
-
Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
-
Martin, M. et al. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Mol. Biol. Cell 10, 3717-3728 (1999).
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3717-3728
-
-
Martin, M.1
-
113
-
-
70450239488
-
Kinesin 1 regulates microtubule dynamics via a c Jun N terminal kinase-dependent mechanism
-
Daire, V. et al. Kinesin 1 regulates microtubule dynamics via a c Jun N terminal kinase-dependent mechanism. J. Biol. Chem. 284, 31992-32001 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 31992-32001
-
-
Daire, V.1
-
114
-
-
34250306791
-
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment
-
Haghnia, M. et al. Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol. Biol. Cell 18, 2081-2089 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2081-2089
-
-
Haghnia, M.1
-
115
-
-
58149091896
-
The mechanism of Ca2+-dependent regulation of kinesin-mediated mitochondrial motility
-
Wang, X. & Schwarz, T. L. The mechanism of Ca2+-dependent regulation of kinesin-mediated mitochondrial motility. Cell 136, 163-174 (2009).
-
(2009)
Cell
, vol.136
, pp. 163-174
-
-
Wang, X.1
Schwarz, T.L.2
-
116
-
-
73949153142
-
Tight functional coupling of kinesin 1A and dynein motors in the bidirectional transport of neurofilaments
-
Uchida, A., Alami, N. H. & Brown, A. Tight functional coupling of kinesin 1A and dynein motors in the bidirectional transport of neurofilaments. Mol. Biol. Cell 20, 4997-5006 (2009).
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4997-5006
-
-
Uchida, A.1
Alami, N.H.2
Brown, A.3
-
117
-
-
10644221121
-
Transport of drosophila fragile x mental retardation protein-containing ribonucleoprotein granules by kinesin 1 and cytoplasmic dynein
-
Ling, S. C., Fahrner, P. S., Greenough, W. T. & Gelfand, V. I. Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin 1 and cytoplasmic dynein. Proc. Natl Acad. Sci. USA 101, 17428-17433 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 17428-17433
-
-
Ling, S.C.1
Fahrner, P.S.2
Greenough, W.T.3
Gelfand, V.I.4
-
118
-
-
6144253216
-
Strong inference: Certain systematic methods of scientific thinking may produce much more rapid progress than others
-
Platt, J. R. Strong inference: Certain systematic methods of scientific thinking may produce much more rapid progress than others. Science 146, 347-353 (1964).
-
(1964)
Science
, vol.146
, pp. 347-353
-
-
Platt, J.R.1
-
120
-
-
77953135927
-
Neck linker length determines the degree of processivity in kinesin 1 and kinesin 2 motors
-
Shastry, S. & Hancock, W. O. Neck linker length determines the degree of processivity in Kinesin 1 and Kinesin 2 motors. Curr. Biol. 20, 939-943 (2010).
-
(2010)
Curr. Biol
, vol.20
, pp. 939-943
-
-
Shastry, S.1
Hancock, W.O.2
-
121
-
-
77449158973
-
Catalysis of the microtubule on rate is the major parameter regulating the depolymerase activity of mcak
-
Cooper, J. R., Wagenbach, M., Asbury, C. L. & Wordeman, L. Catalysis of the microtubule on rate is the major parameter regulating the depolymerase activity of MCAK. Nature Struct. Mol. Biol. 17, 77-82 (2010).
-
(2010)
Nature Struct. Mol. Biol
, vol.17
, pp. 77-82
-
-
Cooper, J.R.1
Wagenbach, M.2
Asbury, C.L.3
Wordeman, L.4
-
122
-
-
60749102596
-
The diffusive interaction of microtubule binding proteins
-
Cooper, J. R. & Wordeman, L. The diffusive interaction of microtubule binding proteins. Curr. Opin. Cell Biol. 21, 68-73 (2009).
-
(2009)
Curr. Opin. Cell Biol
, vol.21
, pp. 68-73
-
-
Cooper, J.R.1
Wordeman, L.2
-
123
-
-
65549171477
-
An end to 40 years of mistakes in dna protein association kinetics
-
Halford, S. E. An end to 40 years of mistakes in DNA protein association kinetics? Biochem. Soc. Trans. 37, 343-348 (2009).
-
(2009)
Biochem Soc. Trans
, vol.37
, pp. 343-348
-
-
Halford, S.E.1
-
124
-
-
0033582814
-
A processive single-headed motor: Kinesin superfamily protein KIF1A
-
Okada, Y& Hirokawa, N. A processive single-headed motor: Kinesin superfamily protein KIF1A. Science 283, 1152-1157 (1999).
-
(1999)
Science
, vol.283
, pp. 1152-1157
-
-
Okada, Y.1
Hirokawa, N.2
-
125
-
-
0034681137
-
Mechanism of the single-headed processivity: Diffusional anchoring between the K loop of kinesin and the C terminus of tubulin
-
Okada, Y. & Hirokawa, N. Mechanism of the single-headed processivity: Diffusional anchoring between the K loop of kinesin and the C terminus of tubulin. Proc. Natl Acad. Sci. USA 97, 640-645 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 640-645
-
-
Okada, Y.1
Hirokawa, N.2
-
126
-
-
0037013148
-
Role of phosphatidylinositol(4 5) bisphosphate organization in membrane transport by the Unc104 kinesin motor
-
Klopfenstein, D. R., Tomishige, M., Stuurman, N. & Vale, R. D. Role of phosphatidylinositol(4,5) bisphosphate organization in membrane transport by the Unc104 kinesin motor. Cell 109, 347-358 (2002).
-
(2002)
Cell
, vol.109
, pp. 347-358
-
-
Klopfenstein, D.R.1
Tomishige, M.2
Stuurman, N.3
Vale, R.D.4
-
127
-
-
65949119126
-
Mammalian Kinesin 3 motors are dimeric in vivo and move by processive motility upon release of autoinhibition
-
Hammond, J. W. et al. Mammalian Kinesin 3 motors are dimeric in vivo and move by processive motility upon release of autoinhibition. PLoS Biol. 7, e72 (2009).
-
(2009)
PLoS Biol
, vol.7
-
-
Hammond, J.W.1
-
128
-
-
49749107045
-
Microtubule cross-linking triggers the directional motility of kinesin 5
-
Kapitein, L. C. et al. Microtubule cross-linking triggers the directional motility of kinesin 5. J. Cell Biol. 182, 421-428 (2008).
-
(2008)
J Cell Biol
, vol.182
, pp. 421-428
-
-
Kapitein, L.C.1
-
129
-
-
70350425612
-
Diffusive movement of processive kinesin 1 on microtubules
-
Lu, H., Ali, M. Y., Bookwalter, C. S., Warshaw, D. M. & Trybus, K. M. Diffusive movement of processive kinesin 1 on microtubules. Traffic 10, 1429-1438 (2009).
-
(2009)
Traffic
, vol.10
, pp. 1429-1438
-
-
Lu, H.1
Ali, M.Y.2
Bookwalter, C.S.3
Warshaw, D.M.4
Trybus, K.M.5
-
130
-
-
33644747344
-
A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules
-
Culver-Hanlon, T. L., Lex, S. A., Stephens, A. D., Quintyne, N. J. & King, S. J. A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules. Nature Cell Biol. 8, 264-270 (2006).
-
(2006)
Nature Cell Biol
, vol.8
, pp. 264-270
-
-
Culver-Hanlon, T.L.1
Lex, S.A.2
Stephens, A.D.3
Quintyne, N.J.4
King, S.J.5
-
131
-
-
0037306229
-
Equilibrium and transition between single-And double-headed binding of kinesin as revealed by single-molecule mechanics
-
Kawaguchi, K., Uemura, S. & Ishiwata, S. Equilibrium and transition between single-And double-headed binding of kinesin as revealed by single-molecule mechanics. Biophys. J. 84, 1103-1113 (2003).
-
(2003)
Biophys. J.
, vol.84
, pp. 1103-1113
-
-
Kawaguchi, K.1
Uemura, S.2
Ishiwata, S.3
-
132
-
-
0037390461
-
Loading direction regulates the affinity of ADP for kinesin
-
Uemura, S. & Ishiwata, S. Loading direction regulates the affinity of ADP for kinesin. Nature Struct. Biol. 10, 308-311 (2003).
-
(2003)
Nature Struct. Biol
, vol.10
, pp. 308-311
-
-
Uemura, S.1
Ishiwata, S.2
-
133
-
-
0037197984
-
Kinesin-microtubule binding depends on both nucleotide state and loading direction
-
Uemura, S. et al. Kinesin-microtubule binding depends on both nucleotide state and loading direction. Proc. Natl Acad. Sci. USA 99, 5977-5981 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 5977-5981
-
-
Uemura, S.1
-
134
-
-
0033193864
-
Kinesin's tail domain is an inhibitory regulator of the motor domain
-
Coy, D. L., Hancock, W. O., Wagenbach, M. & Howard, J. Kinesin's tail domain is an inhibitory regulator of the motor domain. Nature Cell Biol. 1, 288-292 (1999).
-
(1999)
Nature Cell Biol
, vol.1
, pp. 288-292
-
-
Coy, D.L.1
Hancock, W.O.2
Wagenbach, M.3
Howard, J.4
-
135
-
-
0026705754
-
Kinesin undergoes a 9 S to 6 S conformational transition
-
Hackney, D. D., Levitt, J. D. & Suhan, J. Kinesin undergoes a 9 S to 6 S conformational transition. J. Biol. Chem. 267, 8696-8701 (1992).
-
(1992)
J. Biol. Chem
, vol.267
, pp. 8696-8701
-
-
Hackney, D.D.1
Levitt, J.D.2
Suhan, J.3
-
136
-
-
0033771901
-
Kinesin's IAK tail domain inhibits initial microtubule-stimulated ADP release
-
Hackney, D. D. & Stock, M. F. Kinesin's IAK tail domain inhibits initial microtubule-stimulated ADP release. Nature Cell Biol. 2, 257-260 (2000).
-
(2000)
Nature Cell Biol
, vol.2
, pp. 257-260
-
-
Hackney, D.D.1
Stock, M.F.2
-
137
-
-
0033591331
-
Formation of the compact confomer of kinesin requires a COOH-Terminal heavy chain domain and inhibits microtubule-stimulated ATPase activity
-
Stock, M. F. et al. Formation of the compact confomer of kinesin requires a COOH-Terminal heavy chain domain and inhibits microtubule-stimulated ATPase activity. J. Biol. Chem. 274, 14617-14623 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 14617-14623
-
-
Stock, M.F.1
-
138
-
-
0033195492
-
Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain
-
Friedman, D. S. & Vale, R. D. Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain. Nature Cell Biol. 1, 293-297 (1999).
-
(1999)
Nature Cell Biol
, vol.1
, pp. 293-297
-
-
Friedman, D.S.1
Vale, R.D.2
-
139
-
-
77953604433
-
Autoinhibition of the kinesin 2 motor KIF17 via dual intramolecular mechanisms
-
Hammond, J. W., Blasius, T. L., Soppina, V., Cai, D. & Verhey, K. J. Autoinhibition of the kinesin 2 motor KIF17 via dual intramolecular mechanisms. J. Cell Biol. 189, 1013-1025 (2010).
-
(2010)
J. Cell Biol
, vol.189
, pp. 1013-1025
-
-
Hammond, J.W.1
Blasius, T.L.2
Soppina, V.3
Cai, D.4
Verhey, K.J.5
-
140
-
-
40749148904
-
Phosphorylation relieves autoinhibition of the kinetochore motor cenp e
-
Espeut, J. et al. Phosphorylation relieves autoinhibition of the kinetochore motor Cenp E. Mol. Cell 29, 637-643 (2008).
-
(2008)
Mol Cell
, vol.29
, pp. 637-643
-
-
Espeut, J.1
-
141
-
-
80051633233
-
The structure of the kinesin 1 motor-Tail complex reveals the mechanism of autoinhibition
-
Kaan, H. Y., Hackney, D. D. & Kozielski, F. The structure of the kinesin 1 motor-Tail complex reveals the mechanism of autoinhibition. Science 333, 883-885 (2011
-
(2011)
Science
, vol.333
, pp. 883-885
-
-
Kaan, H.Y.1
Hackney, D.D.2
Kozielski, F.3
-
142
-
-
33845967100
-
Two binding partners cooperate to activate the molecular motor Kinesin 1
-
Blasius, T. L., Cai, D., Jih, G. T., Toret, C. P. & Verhey, K. J. Two binding partners cooperate to activate the molecular motor Kinesin 1. J. Cell Biol. 176, 11-17 (2007).
-
(2007)
J Cell Biol
, vol.176
, pp. 11-17
-
-
Blasius, T.L.1
Cai, D.2
Jih, G.T.3
Toret, C.P.4
Verhey, K.J.5
-
143
-
-
34548495093
-
The effector domain of human dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin 3 motor gakin/kif13b
-
Yamada, K H., Hanada, T. & Chishti, A. H. The effector domain of human Dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin 3 motor GAKIN/KIF13B. Biochemistry 46, 10039-10045 (2007).
-
(2007)
Biochemistry
, vol.46
, pp. 10039-10045
-
-
Yamada, K.H.1
Hanada, T.2
Chishti, A.H.3
-
144
-
-
54449089820
-
Regulatory atpase sites of cytoplasmic dynein affect processivity and force generation
-
Cho, C., Reck-Peterson, S. L. & Vale, R. D. Regulatory ATPase sites of cytoplasmic dynein affect processivity and force generation. J. Biol. Chem. 283, 25839-25845 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 25839-25845
-
-
Cho, C.1
Reck-Peterson, S.L.2
Vale, R.D.3
-
146
-
-
60449108890
-
Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses
-
Macaskill, A. F. et al. Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron 61, 541-555 (2009).
-
(2009)
Neuron
, vol.61
, pp. 541-555
-
-
Macaskill, A.F.1
-
147
-
-
0242318330
-
Switching between microtubule-And actin-based transport systems in melanophores is controlled by cAMP levels
-
Rodionov, V., Yi, J., Kashina, A., Oladipo, A. & Gross, S. P. Switching between microtubule-And actin-based transport systems in melanophores is controlled by cAMP levels. Curr. Biol. 13, 1837-1847 (2003).
-
(2003)
Curr. Biol
, vol.13
, pp. 1837-1847
-
-
Rodionov, V.1
Yi, J.2
Kashina, A.3
Oladipo, A.4
Gross, S.P.5
-
148
-
-
0032576766
-
Functional coordination of microtubule-based and actin-based motility in melanophores
-
Rodionov, V. I., Hope, A. J., Svitkina, T. M. & Borisy, G. G. Functional coordination of microtubule-based and actin-based motility in melanophores. Curr. Biol. 8, 165-168 (1998).
-
(1998)
Curr. Biol
, vol.8
, pp. 165-168
-
-
Rodionov, V.I.1
Hope, A.J.2
Svitkina, T.M.3
Borisy, G.G.4
-
149
-
-
84879899805
-
Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking
-
Zajac, A. L., Goldman, Y. E., Holzbaur, E. L. & Ostap, E. M. Local cytoskeletal and organelle interactions impact molecular-motor-driven early endosomal trafficking. Curr. Biol. 23, 1173-1180 (2013).
-
(2013)
Curr. Biol
, vol.23
, pp. 1173-1180
-
-
Zajac, A.L.1
Goldman, Y.E.2
Holzbaur, E.L.3
Ostap, E.M.4
-
150
-
-
34047262039
-
Myosin Va maneuvers through actin intersections and diffuses along microtubules
-
Ali, M. Y. et al. Myosin Va maneuvers through actin intersections and diffuses along microtubules. Proc. Natl Acad. Sci. USA 104, 4332-4336 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 4332-4336
-
-
Ali, M.Y.1
-
151
-
-
42449129759
-
Myosin v and kinesin act as tethers to enhance each others' processivity
-
Ali, M. Y., Lu, H., Bookwalter, C. S., Warshaw, D. M. & Trybus, K. M. Myosin V and Kinesin act as tethers to enhance each others' processivity. Proc. Natl Acad. Sci. USA 105, 4691-4696 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4691-4696
-
-
Ali, M.Y.1
Lu, H.2
Bookwalter, C.S.3
Warshaw, D.M.4
Trybus, K.M.5
-
152
-
-
39149138988
-
Cargo transport: Molecular motors navigate a complex cytoskeleton
-
Ross, J. L., Ali, M. Y. & Warshaw, D. M. Cargo transport: Molecular motors navigate a complex cytoskeleton. Curr. Opin. Cell Biol. 20, 41-47 (2008).
-
(2008)
Curr. Opin. Cell Biol
, vol.20
, pp. 41-47
-
-
Ross, J.L.1
Ali, M.Y.2
Warshaw, D.M.3
-
153
-
-
34547193908
-
Huntingtin facilitates dynein/dynactin-mediated vesicle transport
-
Caviston, J. P., Ross, J. L., Antony, S. M., Tokito, M. & Holzbaur, E. L. Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proc. Natl Acad. Sci. USA 104, 10045-10050 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 10045-10050
-
-
Caviston, J.P.1
Ross, J.L.2
Antony, S.M.3
Tokito, M.4
Holzbaur, E.L.5
-
154
-
-
49149112606
-
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
-
Colin, E. et al. Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. EMBO J. 27, 2124-2134 (2008).
-
(2008)
EMBO J.
, vol.27
, pp. 2124-2134
-
-
Colin, E.1
-
155
-
-
63449090757
-
Huntingtin as an essential integrator of intracellular vesicular trafficking
-
Caviston, J. P. & Holzbaur, E. L. Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends Cell Biol. 19, 147-155 (2009).
-
(2009)
Trends Cell Biol
, vol.19
, pp. 147-155
-
-
Caviston, J.P.1
Holzbaur, E.L.2
-
156
-
-
0035809914
-
Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
-
Verhey, K. J. et al. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J. Cell Biol. 152, 959-970 (2001).
-
(2001)
J. Cell Biol
, vol.152
, pp. 959-970
-
-
Verhey, K.J.1
-
157
-
-
28444496758
-
Aplip1 a kinesin binding jip 1/jnk scaffold protein, influences the axonal transport of both vesicles and mitochondria in drosophila
-
Horiuchi, D., Barkus, R. V., Pilling, A. D., Gassman, A. & Saxton, W. M. APLIP1, a kinesin binding JIP 1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. Curr. Biol. 15, 2137-2141 (2005).
-
(2005)
Curr. Biol
, vol.15
, pp. 2137-2141
-
-
Horiuchi, D.1
Barkus, R.V.2
Pilling, A.D.3
Gassman, A.4
Saxton, W.M.5
-
158
-
-
34547473554
-
Control of a kinesin-cargo linkage mechanism by jnk pathway kinases
-
Horiuchi, D. et al. Control of a kinesin-cargo linkage mechanism by JNK pathway kinases. Curr. Biol. 17, 1313-1317 (2007).
-
(2007)
Curr. Biol
, vol.17
, pp. 1313-1317
-
-
Horiuchi, D.1
-
159
-
-
84887475219
-
Motor domain phosphorylation modulates kinesin 1 transport
-
DeBerg, H. A. et al. Motor domain phosphorylation modulates kinesin 1 transport. J. Biol. Chem. 288, 32612-32621 (2013).
-
(2013)
J. Biol. Chem
, vol.288
, pp. 32612-32621
-
-
Deberg, H.A.1
-
160
-
-
0346037264
-
JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-Associated proteins
-
Chang, L., Jones, Y., Ellisman, M. H., Goldstein, L. S. & Karin, M. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-Associated proteins. Dev. Cell 4, 521-533 (2003).
-
(2003)
Dev. Cell
, vol.4
, pp. 521-533
-
-
Chang, L.1
Jones, Y.2
Ellisman, M.H.3
Goldstein, L.S.4
Karin, M.5
-
161
-
-
33646095177
-
JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length
-
Tararuk, T. et al. JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length. J. Cell Biol. 173, 265-277 (2006).
-
(2006)
J. Cell Biol
, vol.173
, pp. 265-277
-
-
Tararuk, T.1
-
162
-
-
77649105300
-
Global up regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite
-
Stone, M. C., Nguyen, M. M., Tao, J., Allender, D. L. & Rolls, M. M. Global up regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite. Mol. Biol. Cell 21, 767-777 (2010).
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 767-777
-
-
Stone, M.C.1
Nguyen, M.M.2
Tao, J.3
Allender, D.L.4
Rolls, M.M.5
-
163
-
-
84863904678
-
Axon injury and stress trigger a microtubule-based neuroprotective pathway
-
Chen, L., Stone, M. C., Tao, J. & Rolls, M. M. Axon injury and stress trigger a microtubule-based neuroprotective pathway. Proc. Natl Acad. Sci. USA 109, 11842-11847 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 11842-11847
-
-
Chen, L.1
Stone, M.C.2
Tao, J.3
Rolls, M.M.4
-
164
-
-
33645429016
-
Exact stochastic simulation of coupled chemical reactions
-
Gillespie, D. T. Exact stochastic simulation of coupled chemical reactions. J. Phys. Chem. 81, 2340-2361 (1977
-
(1977)
J. Phys. Chem
, vol.81
, pp. 2340-2361
-
-
Gillespie, D.T.1
|