Coordination of opposite-polarity microtubule motors

Journal of Cell Biology

Volumn 156, Issue 4, 2002, Pages 715-724

  Gross, Steven P ^a,d   Welte, Michael A ^b,d   Block, Steven M ^c   Wieschaus, Eric F ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BRANDEIS UNIVERSITY   (United States)

^c STANFORD UNIVERSITY   (United States)

^d PRINCETON UNIVERSITY   (United States)

Author keywords

Bidirectional; Cytoplasmic dynein; Dynactin; Motor coordination; Tug of war

Indexed keywords

DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; FAT DROPLET;

ARTICLE; CYTOLOGY; DROSOPHILA; EMBRYO; MICROTUBULE; MOTOR ACTIVITY; MUTATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; DROSOPHILA MELANOGASTER; DYNEIN ATPASE; FEMALE; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES;

EID: 0037128208     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200109047     Document Type: Article

References (44)

1. Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150
2. Drosophila roadblock and Chlamydomonas LC7: A conserved family of dynein-associated proteins involved in axonal transport, flageliar motility, and mitosis
3. Glued participates in distinct microtubule-based activities in Drosophila eye development
4. Cytoplasmic dynein function is essential in Drosophila melanogaster
5. Bidirectional transport of fluorescently labeled vesicles introduced into extruded axoplasm of squid Loligo pealei
6. Dynein-mediated cargo transport in vivo: A switch controls travel distance
7. Kinesin's IAK tail domain inhibits initial microtubule-stimulated ADP release
8. Processivity of the motor protein kinesin requires two heads
9. Genetic analysis of mutations at the Glued locus and interacting loci in Drosophila melanogaster
10. Microtubule-associated organelle and vesicle transport in fibroblasts
11. The pattern and mechanism of mitochondrial transport in axons
12. Connecting vesicle transport to the cytoskeleron
13. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
14. Dynactin increases the processivity of the cytoplasmic dynein motor
15. Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons
16. Cytoplasmic dynein binds to phospholipid vesicles
17. Nucleotide specificity for the bidirectional transport of membrane-bounded organelles in isolated axoplasm
18. Real-time imaging of the axonal transport of granules containing a tissue plasminogen activator/green fluorescent protein hybrid
19. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
20. Regulation of cytoplasmic dynein function in vivo by the Drosophila Glued complex
21. Molecular analysis of the klarsichtgene and its role in nuclear migration within the differentiating cells of the Drosophila eye
22. Plus-end motors override minus-end motors during transport of squid axon vesicles on microtubules
23. Dynactin-dependenc, dynein-driven vesicle transport in the absence of membrane proteins. A role for spectrin and acidic phospholipids
24. Reconstitution of ATP-dependent movement of endocytic vesicles along microtubules in vitro: An oscillatory bidirectional process
25. Cell cycle regulation ofdynein association with membranes modulates microtubule-based organelle transport
26. Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons
27. Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro
28. The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes
29. Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin
30. Rab6 regulation of rhodopsin transport in Drosophila
31. Herpesviruses use bidirectional fast-axonal transport to spread in sensory neurons
32. Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus
33. Adenovirus-activated PKA and p38/MAPK pathways boost microtubulemediated nuclear targeting of virus
34. Molecular organization and expression of the genetic locus glued in Drosophila melanogaster
35. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
36. Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins
37. Role of dynactin in endocytic traffic: Effects of dynamitin overexpression and colocalization with CLIP-170
38. Light chain-dependent regulation of Kinesin's interaction with microtubules
39. Microtubule-dependent transport of secretory vesicles visualized in real time with a GFP-tagged secretory protein
40. Single cytoplasmic dynein molecule movements: Characterization and comparison with kinesin
41. The p150Glued component of the dynactin complex binds to both microcubules and the actinrelated protein centractin (Atp-1)
42. The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
43. Developmental regulation of vesicle transport in Drosophila embryos: Forces and kinetics
44. Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function in vivo