Control of a Kinesin-Cargo Linkage Mechanism by JNK Pathway Kinases

Current Biology

Volumn 17, Issue 15, 2007, Pages 1313-1317

  Horiuchi, Dai ^a   Collins, Catherine A ^b   Bhat, Pavan ^b   Barkus, Rosemarie V ^a   DiAntonio, Aaron ^b   Saxton, William M ^a  

^a INDIANA UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CELLBIO; SIGNALING

Indexed keywords

APP LIKE PROTEIN INTERACTING PROTEIN 1, DROSOPHILA; APP-LIKE PROTEIN INTERACTING PROTEIN 1, DROSOPHILA; CARRIER PROTEIN; DROSOPHILA PROTEIN; KINESIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; DROSOPHILA; METABOLISM; MICROTUBULE; NERVE FIBER TRANSPORT; TRANSPORT AT THE CELLULAR LEVEL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AXONAL TRANSPORT; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KINESIN; MICROTUBULES;

EID: 34547473554     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2007.06.062     Document Type: Article

References (30)

1. Duncan J.E., and Goldstein L.S. The genetics of axonal transport and axonal transport disorders. PLoS Genet. 2 (2006) e124
2. Hirokawa N., and Takemura R. Molecular motors and mechanisms of directional transport in neurons. Nat. Rev. Neurosci. 6 (2005) 201-214
3. Taru H., Iijima K., Hase M., Kirino Y., Yagi Y., and Suzuki T. Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J. Biol. Chem. 277 (2002) 20070-20078
4. Verhey K.J., Meyer D., Deehan R., Blenis J., Schnapp B.J., Rapoport T.A., and Margolis B. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J. Cell Biol. 152 (2001) 959-970
5. Kelkar N., Standen C.L., and Davis R.J. Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol. Cell. Biol. 25 (2005) 2733-2743
6. Yasuda J., Whitmarsh A.J., Cavanagh J., Sharma M., and Davis R.J. The JIP group of mitogen-activated protein kinase scaffold proteins. Mol. Cell. Biol. 19 (1999) 7245-7254
7. Chevalier-Larsen E., and Holzbaur E.L. Axonal transport and neurodegenerative disease. Biochim. Biophys. Acta 1762 (2006) 1094-1108
8. Hurd D.D., and Saxton W.M. Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics 144 (1996) 1075-1085
9. Bowman A.B., Kamal A., Ritchings B.W., Philp A.V., McGrail M., Gindhart J.G., and Goldstein L.S. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell 103 (2000) 583-594
10. Inomata H., Nakamura Y., Hayakawa A., Takata H., Suzuki T., Miyazawa K., and Kitamura N. A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. J. Biol. Chem. 278 (2003) 22946-22955
11. Matsuda S., Matsuda Y., and D'Adamio L. Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. J. Biol. Chem. 278 (2003) 38601-38606
12. Schnapp B.J. Trafficking of signaling modules by kinesin motors. J. Cell Sci. 116 (2003) 2125-2135
13. Horiuchi D., Barkus R.V., Pilling A.D., Gassman A., and Saxton W.M. APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. Curr. Biol. 15 (2005) 2137-2141
14. Gindhart Jr. J.G., Desai C.J., Beushausen S., Zinn K., and Goldstein L.S. Kinesin light chains are essential for axonal transport in Drosophila. J. Cell Biol. 141 (1998) 443-454
15. Bellen H.J., Levis R.W., Liao G., He Y., Carlson J.W., Tsang G., Evans-Holm M., Hiesinger P.R., Schulze K.L., Rubin G.M., et al. The BDGP gene disruption project: Single transposon insertions associated with 40% of Drosophila genes. Genetics 167 (2004) 761-781
16. Rorth P. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc. Natl. Acad. Sci. USA 93 (1996) 12418-12422
17. DiAntonio A., Haghighi A.P., Portman S.L., Lee J.D., Amaranto A.M., and Goodman C.S. Ubiquitination-dependent mechanisms regulate synaptic growth and function. Nature 412 (2001) 449-452
18. Chen X., and Fischer J.A. In vivo Structure/Function analysis of the Drosophila fat facets deubiquitinating enzyme gene. Genetics 156 (2000) 1829-1836
19. Hershko A., and Ciechanover A. The ubiquitin system. Annu. Rev. Biochem. 67 (1998) 425-479
20. Collins C.A., Wairkar Y.P., Johnson S.L., and DiAntonio A. Highwire restrains synaptic growth by attenuating a MAP kinase signal. Neuron 51 (2006) 57-69
21. Nihalani D., Merritt S., and Holzman L.B. Identification of structural and functional domains in mixed lineage kinase dual leucine zipper-bearing kinase required for complex formation and stress-activated protein kinase activation. J. Biol. Chem. 275 (2000) 7273-7279
22. Gallo K.A., and Johnson G.L. Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nat. Rev. Mol. Cell Biol. 3 (2002) 663-672
23. Merritt S.E., Mata M., Nihalani D., Zhu C., Hu X., and Holzman L.B. The mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrate. J. Biol. Chem. 274 (1999) 10195-10202
24. Stronach B. Dissecting JNK signaling, one KKKinase at a time. Dev. Dyn. 232 (2005) 575-584
25. Verhey K.J., and Rapoport T.A. Kinesin carries the signal. Trends Biochem. Sci. 26 (2001) 545-550
26. Morfini G., Pigino G., Szebenyi G., You Y., Pollema S., and Brady S.T. JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport. Nat. Neurosci. 9 (2006) 907-916
27. Stagi M., Gorlovoy P., Larionov S., Takahashi K., and Neumann H. Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway. FASEB J. 20 (2006) 2573-2575
28. Whitmarsh A.J. The JIP family of MAPK scaffold proteins. Biochem. Soc. Trans. 34 (2006) 828-832
29. Blasius T.L., Cai D., Jih G.T., Toret C.P., and Verhey K.J. Two binding partners cooperate to activate the molecular motor Kinesin-1. J. Cell Biol. 176 (2007) 11-17
30. Stock M.F., Guerrero J., Cobb B., Eggers C.T., Huang T.G., Li X., and Hackney D.D. Formation of the compact confomer of kinesin requires a COOH-terminal heavy chain domain and inhibits microtubule-stimulated ATPase activity. J. Biol. Chem. 274 (1999) 14617-14623