The structure of the kinesin-1 motor-tail complex reveals the mechanism of autoinhibition

Science

Volumn 333, Issue 6044, 2011, Pages 883-885

  Kaan, Hung Yi Kristal ^a   Hackney, David D ^b   Kozielski, Frank ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; DIMER; KINESIN 1;

CHEMICAL BINDING; CRYSTAL STRUCTURE; ESTER; INHIBITION; PHOSPHATE; PROTEIN;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; COVALENT BOND; CROSS LINKING; CRYSTAL STRUCTURE; DISULFIDE BOND; ENZYME AUTOINHIBITION; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; INHIBITION KINETICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STEREOSPECIFICITY; STRUCTURE ANALYSIS;

ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DROSOPHILA PROTEINS; HYDROGEN BONDING; KINESIN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY;

EID: 80051633233     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1204824     Document Type: Article

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