Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization

Science

Volumn 297, Issue 5590, 2002, Pages 2263-2267

  Tomishige, Michio ^a   Klopfenstein, Dieter R ^a   Vale, Ronald D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; MONOMERS; NEUROLOGY;

CONVENTIONAL KINESINS; PROCESSIVE MOTORS;

DIMERIZATION;

KINESIN; PROTEIN KIF 1 A; PROTEIN UNC 104; UNCLASSIFIED DRUG;

BIOCHEMISTRY;

ARTICLE; DIFFUSION; DIMERIZATION; MICROTUBULE; MOTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MODIFICATION; PROTEIN TRANSPORT; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DIFFUSION; DIMERIZATION; HUMANS; KINESIN; LIPOSOMES; MICROTUBULES; MOLECULAR MOTOR PROTEINS; MOLECULAR SEQUENCE DATA; MOVEMENT; MUTATION; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS;

EID: 0037183926     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1073386     Document Type: Article

References (24)

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22. Data not shown.
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24. We thank U. Wiedemann for support in cloning, N. Stuurman and Y. Cui for helpful discussions, and B. Schnapp for providing rat KIFIA cDNA KIF1A CDNA. Supported by grants from the Howard Hughes Medical Institute and NIH (grant AR42895).