메뉴 건너뛰기




Volumn 28, Issue 1, 2014, Pages 21-32

Minocycline modulates cytokine and gene expression profiles in the brain after whole-body exposure to radiation

Author keywords

Apoptosis; Gamma radiation; Inflammation; Mouse model; Radioprotectant

Indexed keywords

BETA CATENIN; INTERLEUKIN 10; INTERLEUKIN 15; MINOCYCLINE; NITRIC OXIDE SYNTHASE; VASCULOTROPIN; NEUROPROTECTIVE AGENT; RADIOPROTECTIVE AGENT; TRANSCRIPTOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

EID: 84906926249     PISSN: 0258851X     EISSN: 17917549     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (80)
  • 1
    • 0027512568 scopus 로고
    • Temporal analysis of the October 1989 proton flare using computerized anatomical models
    • Simonsen LC, Cucinotta FA, Atwell W and Nealy JE: Temporal analysis of the October 1989 proton flare using computerized anatomical models. Radiat Res 133: 1-11, 1993.
    • (1993) Radiat Res , vol.133 , pp. 1-11
    • Simonsen, L.C.1    Cucinotta, F.A.2    Atwell, W.3    Nealy, J.E.4
  • 2
    • 84859359102 scopus 로고    scopus 로고
    • A review of work ongoing at Armed Forces Radiobiology Research Institute
    • Singh VK, Ducey EJ, Brown DS and Whitnall MH: A review of work ongoing at Armed Forces Radiobiology Research Institute. Int J Radiat Biol 88: 296-310, 2001.
    • (2001) Int J Radiat Biol , vol.88 , pp. 296-310
    • Singh, V.K.1    Ducey, E.J.2    Brown, D.S.3    Whitnall, M.H.4
  • 4
    • 1642580864 scopus 로고    scopus 로고
    • Radiation-induced edema is dependent on cyclooxygenase 2 activity in mouse brain
    • Moore AH, Olschowka JA, Williams JP, Paige SL and O'Banion MK: Radiation-induced edema is dependent on cyclooxygenase 2 activity in mouse brain. Radiat Res 161: 153-160, 2004.
    • (2004) Radiat Res , vol.161 , pp. 153-160
    • Moore, A.H.1    Olschowka, J.A.2    Williams, J.P.3    Paige, S.L.4    O'Banion, M.K.5
  • 5
    • 80053255939 scopus 로고    scopus 로고
    • Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain
    • Moravan MJ, Olschowka JA, Williams JP and O'Banion MK: Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain. Radiat Res 176: 459-473, 2011.
    • (2011) Radiat Res , vol.176 , pp. 459-473
    • Moravan, M.J.1    Olschowka, J.A.2    Williams, J.P.3    O'Banion, M.K.4
  • 7
    • 0033032696 scopus 로고    scopus 로고
    • NF kappa B activity and target gene expression in the rat brain after one and two exposures to ionizing radiation
    • Raju U, Gumin GJ and Tofilon PJ: NF kappa B activity and target gene expression in the rat brain after one and two exposures to ionizing radiation. Radiat Oncol Investig 7: 145-152, 1999.
    • (1999) Radiat Oncol Investig , vol.7 , pp. 145-152
    • Raju, U.1    Gumin, G.J.2    Tofilon, P.J.3
  • 8
    • 0033914350 scopus 로고    scopus 로고
    • Radiation-induced transcription factor activation in the rat cerebral cortex
    • Raju U, Gumin GJ and Tofilon PJ: Radiation-induced transcription factor activation in the rat cerebral cortex. Int J Radiat Biol 76: 1045-1053, 2000.
    • (2000) Int J Radiat Biol , vol.76 , pp. 1045-1053
    • Raju, U.1    Gumin, G.J.2    Tofilon, P.J.3
  • 9
    • 84868309553 scopus 로고    scopus 로고
    • Role of PPARs in radiation-induced brain injury
    • Ramanan S, Zhao W, Riddle DR and Robbins ME: Role of PPARs in radiation-induced brain injury. PPAR Res 2010: Article ID 234975, 2010.
    • (2010) PPAR Res , vol.2010
    • Ramanan, S.1    Zhao, W.2    Riddle, D.R.3    Robbins, M.E.4
  • 12
    • 0036239076 scopus 로고    scopus 로고
    • Neural stem cells: Form and function
    • Reh TA: Neural stem cells: form and function. Nat Neurosci 5: 392-394, 2002.
    • (2002) Nat Neurosci , vol.5 , pp. 392-394
    • Reh, T.A.1
  • 13
    • 0033539607 scopus 로고    scopus 로고
    • Running enhances neurogenesis, learning, and long-term potentiation in mice
    • van Praag H, Christie BR, Sejnowski TJ and Gage FH: Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci USA 96: 13427-13431, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13427-13431
    • Van Praag, H.1    Christie, B.R.2    Sejnowski, T.J.3    Gage, F.H.4
  • 14
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann G, Kuhn HG and Gage FH: More hippocampal neurons in adult mice living in an enriched environment. Nature 386: 493-495, 1997.
    • (1997) Nature , vol.386 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 18
    • 34547107081 scopus 로고    scopus 로고
    • A radiobiological review on melatonin: A novel radioprotector
    • Shirazi A, Ghobadi G and Ghazi-Khansari M: A radiobiological review on melatonin: a novel radioprotector. J Radiat Res 48: 263-272, 2007.
    • (2007) J Radiat Res , vol.48 , pp. 263-272
    • Shirazi, A.1    Ghobadi, G.2    Ghazi-Khansari, M.3
  • 19
    • 57549088119 scopus 로고    scopus 로고
    • Minocycline and neurodegenerative diseases
    • Kim HS and Suh YH: Minocycline and neurodegenerative diseases. Behav Brain Res 196: 168-179, 2009.
    • (2009) Behav Brain Res , vol.196 , pp. 168-179
    • Kim, H.S.1    Suh, Y.H.2
  • 20
  • 21
    • 84864999825 scopus 로고    scopus 로고
    • Minocycline benefits negative symptoms in early schizophrenia: A randomised double-blind placebo-controlled clinical trial in patients on standard treatment
    • Chaudhry IB, Hallak J, Husain N, Minhas F, Stirling J, Richardson P, Dursun S, Dunn G and Deakin B: Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment. J Psychopharmacol 26: 1185-1193, 2012.
    • (2012) J Psychopharmacol , vol.26 , pp. 1185-1193
    • Chaudhry, I.B.1    Hallak, J.2    Husain, N.3    Minhas, F.4    Stirling, J.5    Richardson, P.6    Dursun, S.7    Dunn, G.8    Deakin, B.9
  • 24
    • 23244453399 scopus 로고    scopus 로고
    • Antioxidant properties of minocycline: Neuroprotection in an oxidative stress assay and direct radical-scavenging activity
    • Kraus RL, Pasieczny R, Lariosa-Willingham K, Turner MS, Jiang A and Trauger JW: Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity. J Neurochem 94: 819-827, 2005.
    • (2005) J Neurochem , vol.94 , pp. 819-827
    • Kraus, R.L.1    Pasieczny, R.2    Lariosa-Willingham, K.3    Turner, M.S.4    Jiang, A.5    Trauger, J.W.6
  • 25
    • 0034801488 scopus 로고    scopus 로고
    • Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation
    • Tikka T, Usenius T, Tenhunen M, Keinanen R and Koistinaho J: Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation. J Neurochem 78: 1409-1414, 2001.
    • (2001) J Neurochem , vol.78 , pp. 1409-1414
    • Tikka, T.1    Usenius, T.2    Tenhunen, M.3    Keinanen, R.4    Koistinaho, J.5
  • 26
    • 84866610287 scopus 로고    scopus 로고
    • Analysis of minocycline as a countermeasure against acute radiation syndrome
    • Mehrotra S, Pecaut MJ and Gridley DS: Analysis of minocycline as a countermeasure against acute radiation syndrome. In Vivo 26: 743-758, 2012.
    • (2012) In Vivo , vol.26 , pp. 743-758
    • Mehrotra, S.1    Pecaut, M.J.2    Gridley, D.S.3
  • 27
    • 84872743833 scopus 로고    scopus 로고
    • Effects of minocycline on hematopoietic recovery after whole-body irradiation
    • Mehrotra S, Pecaut MJ and Gridley DS: Effects of minocycline on hematopoietic recovery after whole-body irradiation. In Vivo 27: 11-28, 2013.
    • (2013) In Vivo , vol.27 , pp. 11-28
    • Mehrotra, S.1    Pecaut, M.J.2    Gridley, D.S.3
  • 33
    • 0038283161 scopus 로고    scopus 로고
    • Interleukin-10 therapy - Review of a new approach
    • Asadullah K, Sterry W and Volk HD: Interleukin-10 therapy - review of a new approach. Pharmacol Rev 55: 241-269, 2003.
    • (2003) Pharmacol Rev , vol.55 , pp. 241-269
    • Asadullah, K.1    Sterry, W.2    Volk, H.D.3
  • 34
    • 0035341472 scopus 로고    scopus 로고
    • Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity
    • Bachis A, Colangelo AM, Vicini S, Doe PP, De Bernardi MA, Brooker G and Mocchetti I: Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity. J Neurosci 21: 3104-3112, 2001.
    • (2001) J Neurosci , vol.21 , pp. 3104-3112
    • Bachis, A.1    Colangelo, A.M.2    Vicini, S.3    Doe, P.P.4    De Bernardi, M.A.5    Brooker, G.6    Mocchetti, I.7
  • 35
    • 0032865257 scopus 로고    scopus 로고
    • Neuroprotective effects of interleukin-10 following excitotoxic spinal cord injury
    • Brewer KL, Bethea JR and Yezierski RP: Neuroprotective effects of interleukin-10 following excitotoxic spinal cord injury. Exp Neurol 159: 484-493, 1999.
    • (1999) Exp Neurol , vol.159 , pp. 484-493
    • Brewer, K.L.1    Bethea, J.R.2    Yezierski, R.P.3
  • 36
    • 84875266782 scopus 로고    scopus 로고
    • Nerve growth factor-mediated vascular endothelial growth factor expression of astrocyte in retinal vascular development
    • Kim YS, Jo DH, Lee H, Kim JH, Kim KW and Kim JH: Nerve growth factor-mediated vascular endothelial growth factor expression of astrocyte in retinal vascular development. Biochem Biophys Res Commun 431: 740-745, 2013.
    • (2013) Biochem Biophys Res Commun , vol.431 , pp. 740-745
    • Kim, Y.S.1    Jo, D.H.2    Lee, H.3    Kim, J.H.4    Kim, K.W.5    Kim, J.H.6
  • 37
    • 0031839355 scopus 로고    scopus 로고
    • Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1
    • Harmey JH, Dimitriadis E, Kay E, Redmond HP and Bouchier-Hayes D: Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1. Ann Surg Oncol 5: 271-278, 1998.
    • (1998) Ann Surg Oncol , vol.5 , pp. 271-278
    • Harmey, J.H.1    Dimitriadis, E.2    Kay, E.3    Redmond, H.P.4    Bouchier-Hayes, D.5
  • 38
    • 0036822541 scopus 로고    scopus 로고
    • Hypoxia-induced production of stromal cell-derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts
    • Hitchon C, Wong K, Ma G, Reed J, Lyttle D and El-Gabalawy H: Hypoxia-induced production of stromal cell-derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts. Arthritis Rheum 46: 2587-2597, 2002.
    • (2002) Arthritis Rheum , vol.46 , pp. 2587-2597
    • Hitchon, C.1    Wong, K.2    Ma, G.3    Reed, J.4    Lyttle, D.5    El-Gabalawy, H.6
  • 40
    • 77952512347 scopus 로고    scopus 로고
    • Chemotactic and cytotoxic effects of minocycline on human retinal pigment epithelial cells
    • Hollborn M, Wiedemann P, Bringmann A and Kohen L: Chemotactic and cytotoxic effects of minocycline on human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 51: 2721-2729, 2010.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 2721-2729
    • Hollborn, M.1    Wiedemann, P.2    Bringmann, A.3    Kohen, L.4
  • 41
    • 40949122425 scopus 로고    scopus 로고
    • Electroconvulsive seizure restores neurogenesis and hippocampus-dependent fear memory after disruption by irradiation
    • Warner-Schmidt JL, Madsen TM and Duman RS: Electroconvulsive seizure restores neurogenesis and hippocampus-dependent fear memory after disruption by irradiation. Eur J Neurosci 27: 1485-1493, 2008.
    • (2008) Eur J Neurosci , vol.27 , pp. 1485-1493
    • Warner-Schmidt, J.L.1    Madsen, T.M.2    Duman, R.S.3
  • 42
    • 77956124441 scopus 로고    scopus 로고
    • Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2
    • Kernt M, Neubauer AS, Eibl KH, Wolf A, Ulbig MW, Kampik A and Hirneiss C: Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2. Clin Ophthalmol 4: 591-604, 2010.
    • (2010) Clin Ophthalmol , vol.4 , pp. 591-604
    • Kernt, M.1    Neubauer, A.S.2    Eibl, K.H.3    Wolf, A.4    Ulbig, M.W.5    Kampik, A.6    Hirneiss, C.7
  • 47
    • 79959240248 scopus 로고    scopus 로고
    • Interleukin-15 regulates proliferation and self-renewal of adult neural stem cells
    • Gomez-Nicola D, Valle-Argos B, Pallas-Bazarra N and Nieto-Sampedro M: Interleukin-15 regulates proliferation and self-renewal of adult neural stem cells. Mol Bio Cell 22: 1960-1970, 2011.
    • (2011) Mol Bio Cell , vol.22 , pp. 1960-1970
    • Gomez-Nicola, D.1    Valle-Argos, B.2    Pallas-Bazarra, N.3    Nieto-Sampedro, M.4
  • 48
    • 77954481680 scopus 로고    scopus 로고
    • Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity - A tale of conflict and conundrum
    • Müller M, Carter S, Hofer MJ and Campbell IL: Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity - a tale of conflict and conundrum. Neuropathol Appl Neurobiol 36: 368-387, 2010.
    • (2010) Neuropathol Appl Neurobiol , vol.36 , pp. 368-387
    • Müller, M.1    Carter, S.2    Hofer, M.J.3    Campbell, I.L.4
  • 49
    • 0028289254 scopus 로고
    • Constitutive expression of IP-10 in lymphoid organs and inducible expression in T cells and thymocytes
    • Gattass CR, King LB, Luster AD and Ashwell JD: Constitutive expression of IP-10 in lymphoid organs and inducible expression in T cells and thymocytes. J Exp Med 179: 1373-1378, 1994.
    • (1994) J Exp Med , vol.179 , pp. 1373-1378
    • Gattass, C.R.1    King, L.B.2    Luster, A.D.3    Ashwell, J.D.4
  • 51
    • 84867017339 scopus 로고    scopus 로고
    • Low dose ionizing radiation leads to a NF-kB dependent decrease secretion of active IL-1β by activated macrophages with a discontinuous dose-dependency
    • Lödermann B, Wunderlich R, Frey S, Schorn C, Stangl S, Rödel F, Keilholz L, Fietkau R, Gaipl US and Frey B: Low dose ionizing radiation leads to a NF-kB dependent decrease secretion of active IL-1β by activated macrophages with a discontinuous dose-dependency. Int J Radiat Biol 88: 727-734, 2012.
    • (2012) Int J Radiat Biol , vol.88 , pp. 727-734
    • Lödermann, B.1    Wunderlich, R.2    Frey, S.3    Schorn, C.4    Stangl, S.5    Rödel, F.6    Keilholz, L.7    Fietkau, R.8    Gaipl, U.S.9    Frey, B.10
  • 52
    • 84870880129 scopus 로고    scopus 로고
    • Cytokines in radiobiological responses: A review
    • Schaue D, Kachikwu EL and McBride WH: Cytokines in radiobiological responses: a review. Radiat Res 178: 505-523, 2012.
    • (2012) Radiat Res , vol.178 , pp. 505-523
    • Schaue, D.1    Kachikwu, E.L.2    McBride, W.H.3
  • 54
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T, Fiebich BL, Goldsteins G, Keinanen R and Koistinaho J: Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 21: 2580-2588, 2001.
    • (2001) J Neurosci , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 55
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in cns injury and disease
    • Lucas SM, Rothwell NJ and Gibson RM: The role of inflammation in cns injury and disease. Br J Pharmacol 147(Suppl 1): S232-S240, 2006.
    • (2006) Br J Pharmacol , vol.147 , pp. S232-S240
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 56
    • 0032950857 scopus 로고    scopus 로고
    • Annual review prize lecture: Cytokines - Killers in the brain?
    • Rothwell NJ: Annual review prize lecture: cytokines - killers in the brain? J Physiol 514(Pt 1): 3-17, 1999.
    • (1999) J Physiol , vol.514 , pp. 3-17
    • Rothwell, N.J.1
  • 57
    • 46849088998 scopus 로고    scopus 로고
    • Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
    • Pott Godoy MC, Tarelli R, Ferrari CC, Sarchi MI and Pitossi FJ: Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease. Brain 131: 1880-1894, 2008.
    • (2008) Brain , vol.131 , pp. 1880-1894
    • Pott Godoy, M.C.1    Tarelli, R.2    Ferrari, C.C.3    Sarchi, M.I.4    Pitossi, F.J.5
  • 58
    • 33644869901 scopus 로고    scopus 로고
    • Inflammation and neurodegenerative diseases
    • Griffin WS: Inflammation and neurodegenerative diseases. Am J Clin Nutr 83: 470S-474S, 2006.
    • (2006) Am J Clin Nutr , vol.83 , pp. 470S-474S
    • Griffin, W.S.1
  • 59
    • 60649107163 scopus 로고    scopus 로고
    • Neural precursor cells and central nervous system radiation sensitivity
    • Fike JR, Rosi S and Limoli CL: Neural precursor cells and central nervous system radiation sensitivity. Semin Radiat Oncol 19: 122-132, 2009.
    • (2009) Semin Radiat Oncol , vol.19 , pp. 122-132
    • Fike, J.R.1    Rosi, S.2    Limoli, C.L.3
  • 61
    • 84859717206 scopus 로고    scopus 로고
    • Innate immunity in the central nervous system
    • Ransohoff RM and Brown MA: Innate immunity in the central nervous system. J Clin Invest 122: 1164-171, 2012
    • (2012) J Clin Invest , vol.122 , pp. 1164-1171
    • Ransohoff, R.M.1    Brown, M.A.2
  • 62
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • Mantovani A, Cassatella MA, Costantini C and Jaillon S: Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 11: 519-531, 2011.
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 63
    • 84856034604 scopus 로고    scopus 로고
    • Neuroinflammation: A common pathway in CNS diseases as mediated at the bloodbrain barrier
    • Erickson MA, Dohi K and Banks WA: Neuroinflammation: a common pathway in CNS diseases as mediated at the bloodbrain barrier. Neuroimmunomodulation 19: 121-130, 2012.
    • (2012) Neuroimmunomodulation , vol.19 , pp. 121-130
    • Erickson, M.A.1    Dohi, K.2    Banks, W.A.3
  • 64
    • 84879160847 scopus 로고    scopus 로고
    • Long-term alterations of cell population in the adult rat forebrain following the exposure to fractionated doses of ionizing radiation
    • Bálentová S, Haltmanová E, Kinclová I, Lehotský J, Dobrota D and Adamkov M: Long-term alterations of cell population in the adult rat forebrain following the exposure to fractionated doses of ionizing radiation. Gen Physiol Biophys 32: 91-100, 2013.
    • (2013) Gen Physiol Biophys , vol.32 , pp. 91-100
    • Bálentová, S.1    Haltmanová, E.2    Kinclová, I.3    Lehotský, J.4    Dobrota, D.5    Adamkov, M.6
  • 65
    • 84865477014 scopus 로고    scopus 로고
    • Effect of acute and fractionated irradiation on hippocampal neurogenesis
    • Park MK, Kim S, Jung U, Kim I, Kim JK and Roh C: Effect of acute and fractionated irradiation on hippocampal neurogenesis. Molecules 17: 9462-9468, 2012.
    • (2012) Molecules , vol.17 , pp. 9462-9468
    • Park, M.K.1    Kim, S.2    Jung, U.3    Kim, I.4    Kim, J.K.5    Roh, C.6
  • 66
    • 0033528280 scopus 로고    scopus 로고
    • Neuroprotective effects of growth/differentiation factor 5 depend on the site of administration
    • Sullivan AM, Opacka-Juffry J, Pohl J and Blunt SB: Neuroprotective effects of growth/differentiation factor 5 depend on the site of administration. Brain Res 818: 176-179, 1999.
    • (1999) Brain Res , vol.818 , pp. 176-179
    • Sullivan, A.M.1    Opacka-Juffry, J.2    Pohl, J.3    Blunt, S.B.4
  • 67
    • 71749092275 scopus 로고    scopus 로고
    • The TNF superfamily in 2009: New pathways, new indications, and new drugs
    • Tansey MG and Szymkowski DE: The TNF superfamily in 2009: new pathways, new indications, and new drugs. Drug Discov Today 14: 1082-1088, 2009.
    • (2009) Drug Discov Today , vol.14 , pp. 1082-1088
    • Tansey, M.G.1    Szymkowski, D.E.2
  • 68
    • 79957933723 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors attenuate neuroinflammation following focal cerebral ischemia in mice
    • Park CH, Shin TK, Lee HY, Kim SJ and Lee WS: Matrix metalloproteinase inhibitors attenuate neuroinflammation following focal cerebral ischemia in mice. Korean J Physiol Pharmacol 15: 115-122, 2011.
    • (2011) Korean J Physiol Pharmacol , vol.15 , pp. 115-122
    • Park, C.H.1    Shin, T.K.2    Lee, H.Y.3    Kim, S.J.4    Lee, W.S.5
  • 69
    • 0036935247 scopus 로고    scopus 로고
    • Bone morphogenetic proteins but not growth differentiation factors induce dopaminergic differentiation in mesencephalic precursors
    • Brederlau A, Faigle R, Kaplan P, Odin P and Funa K: Bone morphogenetic proteins but not growth differentiation factors induce dopaminergic differentiation in mesencephalic precursors. Mol Cell Neurosci 21: 367-378, 2002.
    • (2002) Mol Cell Neurosci , vol.21 , pp. 367-378
    • Brederlau, A.1    Faigle, R.2    Kaplan, P.3    Odin, P.4    Funa, K.5
  • 70
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • Ajami B, Bennett JL, Krieger C, Tetzlaff W and Rossi FM: Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci 10: 1538-1543, 2007.
    • (2007) Nat Neurosci , vol.10 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.5
  • 71
    • 84867819155 scopus 로고    scopus 로고
    • Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood-brain barrier through paracellular transmigration and ERK activation
    • Sagar D, Lamontagne A, Foss CA, Khan ZK, Pomper MG and Jain P: Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood-brain barrier through paracellular transmigration and ERK activation. J Neuroinflammation 9: Article 245, 2012.
    • (2012) J Neuroinflammation , vol.9
    • Sagar, D.1    Lamontagne, A.2    Foss, C.A.3    Khan, Z.K.4    Pomper, M.G.5    Jain, P.6
  • 73
    • 0035115572 scopus 로고    scopus 로고
    • Minocycline inhibits the production of inducible nitric oxide synthase in articular chondrocytes
    • Sadowski T and Steinmeyer J: Minocycline inhibits the production of inducible nitric oxide synthase in articular chondrocytes. J Rheumatol 28: 336-340, 2001.
    • (2001) J Rheumatol , vol.28 , pp. 336-340
    • Sadowski, T.1    Steinmeyer, J.2
  • 74
    • 7244242682 scopus 로고    scopus 로고
    • Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following INOS/NO induction by lipopolysaccharide in neuron/glia co-cultures
    • Lee SM, Yune TY, Kim SJ, Kim YC, Oh YJ, Markelonis GJ and Oh TH: Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following INOS/NO induction by lipopolysaccharide in neuron/glia co-cultures. J Neurochem 91: 568-578, 2004.
    • (2004) J Neurochem , vol.91 , pp. 568-578
    • Lee, S.M.1    Yune, T.Y.2    Kim, S.J.3    Kim, Y.C.4    Oh, Y.J.5    Markelonis, G.J.6    Oh, T.H.7
  • 75
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • Macdonald BT, Tamai K and He X: Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17: 9-26, 2009.
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • Macdonald, B.T.1    Tamai, K.2    He, X.3
  • 76
    • 84860285299 scopus 로고    scopus 로고
    • Low-dose radiation stimulates Wnt/β-catenin signaling, neural stem cell proliferation and neurogenesis of the mouse hippocampus in vitro and in vivo
    • Wei LC, Ding YX, Liu YH, Duan L, Bai Y, Shi M and Chen LW: Low-dose radiation stimulates Wnt/β-catenin signaling, neural stem cell proliferation and neurogenesis of the mouse hippocampus in vitro and in vivo. Curr Alzheimer Res 9: 278-289, 2012.
    • (2012) Curr Alzheimer Res , vol.9 , pp. 278-289
    • Wei, L.C.1    Ding, Y.X.2    Liu, Y.H.3    Duan, L.4    Bai, Y.5    Shi, M.6    Chen, L.W.7
  • 77
    • 18144367783 scopus 로고    scopus 로고
    • p53 mutation heterogeneity in cancer
    • Soussi T and Lozano G: p53 mutation heterogeneity in cancer. Biochem Biophys Res Commun 331: 834-842, 2005.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 834-842
    • Soussi, T.1    Lozano, G.2
  • 78
    • 11244344381 scopus 로고    scopus 로고
    • p53: Traffic cop at the crossroads of DNA repair and recombination
    • Sengupta S and Harris CC: p53: traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol 6: 44-55, 2005.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 44-55
    • Sengupta, S.1    Harris, C.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.