-
1
-
-
0141815531
-
The Swedish Council on Technology Assessment in Health Care (SBU) systematic overview of radiotherapy for cancer including a prospective survey of radiotherapy practice in Sweden 2001-summary and conclusions
-
Ringborg U, Bergqvist D, Brorsson B et al. The Swedish Council on Technology Assessment in Health Care (SBU) systematic overview of radiotherapy for cancer including a prospective survey of radiotherapy practice in Sweden 2001-summary and conclusions. Acta Oncol 2003;42:357-365.
-
(2003)
Acta Oncol
, vol.42
, pp. 357-365
-
-
Ringborg, U.1
Bergqvist, D.2
Brorsson, B.3
-
2
-
-
9244246263
-
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries
-
Report of an NCI Workshop, December 3-4, 2003
-
Stone HB, Moulder JE, Coleman CN et al. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res 2004;162: 711-728.
-
(2004)
Radiat Res
, vol.162
, pp. 711-728
-
-
Stone, H.B.1
Moulder, J.E.2
Coleman, C.N.3
-
5
-
-
0037078918
-
Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage
-
Xavier S, Yamada K, Samuni AM et al. Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage. Biochim Biophys Acta 2002;1573:109-120.
-
(2002)
Biochim Biophys Acta
, vol.1573
, pp. 109-120
-
-
Xavier, S.1
Yamada, K.2
Samuni, A.M.3
-
6
-
-
0000416892
-
Cysteine protection against X irradiation
-
Patt HM, Tyree EB, Straube RL et al. Cysteine protection against X irradiation. Science 1949;110:213-214.
-
(1949)
Science
, vol.110
, pp. 213-214
-
-
Patt, H.M.1
Tyree, E.B.2
Straube, R.L.3
-
7
-
-
12744277800
-
The amines and particularly cysteamine as protectors against roentgen rays
-
Bacq ZM. The amines and particularly cysteamine as protectors against roentgen rays. Acta Radiol 1954;41:47-55.
-
(1954)
Acta Radiol
, vol.41
, pp. 47-55
-
-
Bacq, Z.M.1
-
8
-
-
0023754443
-
Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: WR-2721, cysteamine, diethyldithiocarbamate, and N-acetylcysteine
-
Landauer MR, Davis HD, Dominitz JA et al. Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: WR-2721, cysteamine, diethyldithiocarbamate, and N-acetylcysteine. Pharmacol Ther 1988;39:97-100.
-
(1988)
Pharmacol Ther
, vol.39
, pp. 97-100
-
-
Landauer, M.R.1
Davis, H.D.2
Dominitz, J.A.3
-
9
-
-
0021914053
-
Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721
-
Calabro-Jones PM, Fahey RC, Smoluk GD et al. Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721. Int J Radiat Biol Relat Stud Phys Chem Med 1985;47:23-27.
-
(1985)
Int J Radiat Biol Relat Stud Phys Chem Med
, vol.47
, pp. 23-27
-
-
Calabro-Jones, P.M.1
Fahey, R.C.2
Smoluk, G.D.3
-
10
-
-
0018839016
-
Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphos-phorothioic acid
-
Yuhas JM. Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphos-phorothioic acid. Cancer Res 1980;40:1519-1524.
-
(1980)
Cancer Res
, vol.40
, pp. 1519-1524
-
-
Yuhas, J.M.1
-
11
-
-
0020603425
-
Interaction of cultured mammalian cells with WR-2721 and its thiol, WR-1065: Implications for mechanisms of radioprotection
-
Purdie JW, Inhaber ER, Schneider H et al. Interaction of cultured mammalian cells with WR-2721 and its thiol, WR-1065: Implications for mechanisms of radioprotection. Int J Radiat Biol Relat Stud Phys Chem Med 1983;43:517-527.
-
(1983)
Int J Radiat Biol Relat Stud Phys Chem Med
, vol.43
, pp. 517-527
-
-
Purdie, J.W.1
Inhaber, E.R.2
Schneider, H.3
-
13
-
-
8244222299
-
Thiol WR-1065 and disulphide WR-33278, two metabolites of the drug ethyol (WR-2721), protect DNA against fast neutron-induced strand breakage
-
Savoye C, Swenberg C, Hugot S et al. Thiol WR-1065 and disulphide WR-33278, two metabolites of the drug ethyol (WR-2721), protect DNA against fast neutron-induced strand breakage. Int J Radiat Biol 1997;71:193-202.
-
(1997)
Int J Radiat Biol
, vol.71
, pp. 193-202
-
-
Savoye, C.1
Swenberg, C.2
Hugot, S.3
-
14
-
-
34447116285
-
Amifostine: The first selective-target and broad-spectrum radioprotector
-
Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: The first selective-target and broad-spectrum radioprotector. The Oncologist 2007;12:738-747.
-
(2007)
The Oncologist
, vol.12
, pp. 738-747
-
-
Kouvaris, J.R.1
Kouloulias, V.E.2
Vlahos, L.J.3
-
15
-
-
0037096826
-
2002 update of recommendations for the use of chemotherapy and radiotherapy protectants: Clinical practice guidelines of the American Society of Clinical Oncology
-
Schuchter LM, Hensley ML, Meropol NJ et al. 2002 update of recommendations for the use of chemotherapy and radiotherapy protectants: Clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2002;20:2895-2903.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2895-2903
-
-
Schuchter, L.M.1
Hensley, M.L.2
Meropol, N.J.3
-
16
-
-
58149335531
-
American Society of Clinical Oncology 2008 clinical practice guideline update: Use of chemotherapy and radiation therapy protectants
-
Hensley ML, Hagerty KL, Kewalramani T et al. American Society of Clinical Oncology 2008 clinical practice guideline update: Use of chemotherapy and radiation therapy protectants. J Clin Oncol 2009;27:127-145.
-
(2009)
J Clin Oncol
, vol.27
, pp. 127-145
-
-
Hensley, M.L.1
Hagerty, K.L.2
Kewalramani, T.3
-
17
-
-
0038071449
-
Does amifostine have a role in chemoradiation treatment?
-
Brizel DM, Overgaard J. Does amifostine have a role in chemoradiation treatment? Lancet Oncol 2003;4:378-381.
-
(2003)
Lancet Oncol
, vol.4
, pp. 378-381
-
-
Brizel, D.M.1
Overgaard, J.2
-
18
-
-
34648816658
-
Therapeutic and clinical applications of nitroxide compounds
-
Soule BP, Hyodo F, Matsumoto K et al. Therapeutic and clinical applications of nitroxide compounds. Antioxid Redox Signal 2007;9:1731-1743.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1731-1743
-
-
Soule, B.P.1
Hyodo, F.2
Matsumoto, K.3
-
19
-
-
0026050304
-
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol
-
Mitchell JB, DeGraff W, Kaufman D et al. Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol. Arch Biochem Biophys 1991;289:62-70.
-
(1991)
Arch Biochem Biophys
, vol.289
, pp. 62-70
-
-
Mitchell, J.B.1
Degraff, W.2
Kaufman, D.3
-
20
-
-
0026664064
-
Tempol, a stable free radical, is a novel murine radiation protector
-
Hahn SM, Tochner Z, Krishna CM et al. Tempol, a stable free radical, is a novel murine radiation protector. Cancer Res 1992;52:1750-1753.
-
(1992)
Cancer Res
, vol.52
, pp. 1750-1753
-
-
Hahn, S.M.1
Tochner, Z.2
Krishna, C.M.3
-
21
-
-
0001039237
-
Protection from radiation-induced alopecia with topical application of nitroxides: Fractionated studies
-
Cuscela D, Coffin D, Lupton GP et al. Protection from radiation-induced alopecia with topical application of nitroxides: Fractionated studies. Cancer J Sci Am 1996;2:273-278.
-
(1996)
Cancer J Sci Am
, vol.2
, pp. 273-278
-
-
Cuscela, D.1
Coffin, D.2
Lupton, G.P.3
-
22
-
-
0026548016
-
Topical application of nitroxide protects radiation-induced alopecia in guinea pigs
-
Goffman T, Cuscela D, Glass J et al. Topical application of nitroxide protects radiation-induced alopecia in guinea pigs. Int J Radiat Oncol Biol Phys 1992;22:803-806.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.22
, pp. 803-806
-
-
Goffman, T.1
Cuscela, D.2
Glass, J.3
-
23
-
-
5144231707
-
A phase I study of topical Tempol for the prevention of alopecia induced by whole brain radiotherapy
-
Metz JM, Smith D, Mick R et al. A phase I study of topical Tempol for the prevention of alopecia induced by whole brain radiotherapy. Clin Cancer Res 2004;10:6411-6417.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6411-6417
-
-
Metz, J.M.1
Smith, D.2
Mick, R.3
-
24
-
-
34548068806
-
Differential radiation protection of salivary glands versus tumor by Tempol with accompanying tissue assessment of Tempol by magnetic resonance imaging
-
Cotrim AP, Hyodo F, Matsumoto K et al. Differential radiation protection of salivary glands versus tumor by Tempol with accompanying tissue assessment of Tempol by magnetic resonance imaging. Clin Cancer Res 2007;13:4928-4933.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4928-4933
-
-
Cotrim, A.P.1
Hyodo, F.2
Matsumoto, K.3
-
25
-
-
33646394317
-
High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents
-
Matsumoto K, Hyodo F, Matsumoto A et al. High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents. Clin Cancer Res 2006;12:2455-2462.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2455-2462
-
-
Matsumoto, K.1
Hyodo, F.2
Matsumoto, A.3
-
26
-
-
33750553403
-
Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents
-
Hyodo F, Matsumoto K, Matsumoto A et al. Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents. Cancer Res 2006;66:9921-9928.
-
(2006)
Cancer Res
, vol.66
, pp. 9921-9928
-
-
Hyodo, F.1
Matsumoto, K.2
Matsumoto, A.3
-
27
-
-
52449117453
-
Effects of radiation and alpha-tocopherol on saliva flow rate, amylase activity, total protein and electrolyte levels in oral cavity cancer
-
Chitra S, Shyamala Devi CS. Effects of radiation and alpha-tocopherol on saliva flow rate, amylase activity, total protein and electrolyte levels in oral cavity cancer. Indian J Dent Res 2008;19:213-218.
-
(2008)
Indian J Dent Res
, vol.19
, pp. 213-218
-
-
Chitra, S.1
Shyamala Devi, C.S.2
-
28
-
-
24944500925
-
Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients
-
Bairati I, Meyer F, Gélinas M et al. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. J Clin Oncol 2005;23:5805-5813.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5805-5813
-
-
Bairati, I.1
Meyer, F.2
Gélinas, M.3
-
29
-
-
1842421979
-
Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: A double-blind randomized trial
-
Ferreira PR, Fleck JF, Diehl A et al. Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: A double-blind randomized trial. Head Neck 2004;26:313-321.
-
(2004)
Head Neck
, vol.26
, pp. 313-321
-
-
Ferreira, P.R.1
Fleck, J.F.2
Diehl, A.3
-
30
-
-
36248992380
-
Pentoxifylline and alpha-tocopherol in prevention of radiation-induced lung toxicity in patients with lung cancer
-
Misirlioglu CH, Demirkasimoglu T, Kucukplakci B et al. Pentoxifylline and alpha-tocopherol in prevention of radiation-induced lung toxicity in patients with lung cancer. Med Oncol 2007;24:308-311.
-
(2007)
Med Oncol
, vol.24
, pp. 308-311
-
-
Misirlioglu, C.H.1
Demirkasimoglu, T.2
Kucukplakci, B.3
-
31
-
-
0029738838
-
Prevention of radioinduced cystitis by orgotein: A randomized study
-
Sanchiz F, Milla A, Artola N et al. Prevention of radioinduced cystitis by orgotein: A randomized study. Anticancer Res 1996;16:2025-2028.
-
(1996)
Anticancer Res
, vol.16
, pp. 2025-2028
-
-
Sanchiz, F.1
Milla, A.2
Artola, N.3
-
32
-
-
0027277108
-
A double-blind, randomized, prospective trial to evaluate topical vitamin C solution for the prevention of radiation dermatitis. CNS Cancer Consortium
-
Halperin EC, Gaspar L, George S et al. A double-blind, randomized, prospective trial to evaluate topical vitamin C solution for the prevention of radiation dermatitis. CNS Cancer Consortium. Int J Radiat Oncol Biol Phys 1993;26:413-416.
-
(1993)
Int J Radiat Oncol Biol Phys
, vol.26
, pp. 413-416
-
-
Halperin, E.C.1
Gaspar, L.2
George, S.3
-
33
-
-
24944531781
-
Implications for tumor control during protection of normal tissues with antioxidants
-
Camphausen K, Citrin D, Krishna MC et al. Implications for tumor control during protection of normal tissues with antioxidants. J Clin Oncol 2005; 23:5455-5457.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5455-5457
-
-
Camphausen, K.1
Citrin, D.2
Krishna, M.C.3
-
34
-
-
39649110870
-
Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: A randomized trial among head and neck cancer patients
-
Meyer F, Bairati I, Fortin A et al. Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: A randomized trial among head and neck cancer patients. Int J Cancer 2008;122:1679-1683.
-
(2008)
Int J Cancer
, vol.122
, pp. 1679-1683
-
-
Meyer, F.1
Bairati, I.2
Fortin, A.3
-
35
-
-
0037338423
-
Prevention of radiation-induced oral cavity mucositis by plasmid/liposome delivery of the human manganese superoxide dismutase (SOD2) transgene
-
Guo H, Seixas-Silva JA Jr, Epperly MW et al. Prevention of radiation-induced oral cavity mucositis by plasmid/liposome delivery of the human manganese superoxide dismutase (SOD2) transgene. Radiat Res 2003;159: 361-370.
-
(2003)
Radiat Res
, vol.159
, pp. 361-370
-
-
Guo, H.1
Seixas-Silva Jr., J.A.2
Epperly, M.W.3
-
36
-
-
0032888334
-
Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene
-
Stickle RL, Epperly MW, Klein E et al. Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene. Radiat Oncol Investig 1999;7:204-217.
-
(1999)
Radiat Oncol Investig
, vol.7
, pp. 204-217
-
-
Stickle, R.L.1
Epperly, M.W.2
Klein, E.3
-
37
-
-
0032897928
-
Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis
-
Epperly MW, Bray JA, Krager S et al. Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis. Int J Radiat Oncol Biol Phys 1999;43:169-181.
-
(1999)
Int J Radiat Oncol Biol Phys
, vol.43
, pp. 169-181
-
-
Epperly, M.W.1
Bray, J.A.2
Krager, S.3
-
38
-
-
0032605109
-
Manganese [correction of Magnesium] superoxide dismutase (MnSOD) plasmid/liposome pulmonary radio-protective gene therapy: Modulation of irradiation-induced mRNA for IL-I, TNF-alpha, and TGF-beta correlates with delay of organizing alveolitis/ fibrosis
-
Epperly MW, Travis EL, Sikora C et al. Manganese [correction of Magnesium] superoxide dismutase (MnSOD) plasmid/liposome pulmonary radio-protective gene therapy: Modulation of irradiation-induced mRNA for IL-I, TNF-alpha, and TGF-beta correlates with delay of organizing alveolitis/ fibrosis. Biol Blood Marrow Transplant 1999;5:204-214.
-
(1999)
Biol Blood Marrow Transplant
, vol.5
, pp. 204-214
-
-
Epperly, M.W.1
Travis, E.L.2
Sikora, C.3
-
39
-
-
0034131278
-
Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation
-
Epperly MW, Defilippi S, Sikora C et al. Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation. Gene Ther 2000;7:1011-1018.
-
(2000)
Gene Ther
, vol.7
, pp. 1011-1018
-
-
Epperly, M.W.1
Defilippi, S.2
Sikora, C.3
-
40
-
-
0028066981
-
Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial
-
Delanian S, Baillet F, Huart J et al. Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial. Radiother Oncol 1994;32:12-20.
-
(1994)
Radiother Oncol
, vol.32
, pp. 12-20
-
-
Delanian, S.1
Baillet, F.2
Huart, J.3
-
41
-
-
0029996626
-
Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: An experimental study
-
Lefaix JL, Delanian S, Leplat JJ et al. Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: An experimental study. Int J Radiat Oncol Biol Phys 1996;35:305-312.
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.35
, pp. 305-312
-
-
Lefaix, J.L.1
Delanian, S.2
Leplat, J.J.3
-
42
-
-
0029030504
-
Expression of manganese superoxide dismutase reduces tumor control radiation dose: Gene-radiotherapy
-
Urano M, Kuroda M, Reynolds R et al. Expression of manganese superoxide dismutase reduces tumor control radiation dose: Gene-radiotherapy. Cancer Res 1995;55:2490-2493.
-
(1995)
Cancer Res
, vol.55
, pp. 2490-2493
-
-
Urano, M.1
Kuroda, M.2
Reynolds, R.3
-
43
-
-
0037198063
-
Reactive oxygen and nitrogen species and cellular and organismal decline: Amelioration with melatonin
-
Reiter RJ, Tan DX, Burkhardt S. Reactive oxygen and nitrogen species and cellular and organismal decline: Amelioration with melatonin. Mech Ageing Dev 2002;123:1007-1019.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 1007-1019
-
-
Reiter, R.J.1
Tan, D.X.2
Burkhardt, S.3
-
44
-
-
1042279497
-
Melatonin: Detoxification of oxygen and nitrogen-based toxic reactants
-
Reiter RJ, Tan DX, Manchester LC et al. Melatonin: Detoxification of oxygen and nitrogen-based toxic reactants. Adv Exp Med Biol 2003;527: 539-548.
-
(2003)
Adv Exp Med Biol
, vol.527
, pp. 539-548
-
-
Reiter, R.J.1
Tan, D.X.2
Manchester, L.C.3
-
45
-
-
0037404268
-
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: A study of their individual and synergistic actions
-
Lopez-Burillo S, Tan DX, Mayo JC et al. Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: A study of their individual and synergistic actions. J Pineal Res 2003;34:269-277.
-
(2003)
J Pineal Res
, vol.34
, pp. 269-277
-
-
Lopez-Burillo, S.1
Tan, D.X.2
Mayo, J.C.3
-
46
-
-
0033002666
-
The effect of melatonin on lipid peroxidation during radiotherapy in female rats
-
Kaya H, Delibas N, Serteser M et al. The effect of melatonin on lipid peroxidation during radiotherapy in female rats. Strahlenther Onkol 1999;175: 285-288.
-
(1999)
Strahlenther Onkol
, vol.175
, pp. 285-288
-
-
Kaya, H.1
Delibas, N.2
Serteser, M.3
-
47
-
-
0035046321
-
Melatonin stimulates glutathione peroxidase activity in human chorion
-
Okatani Y, Wakatsuki A, Shinohara K et al. Melatonin stimulates glutathione peroxidase activity in human chorion. J Pineal Res 2001;30:199-205.
-
(2001)
J Pineal Res
, vol.30
, pp. 199-205
-
-
Okatani, Y.1
Wakatsuki, A.2
Shinohara, K.3
-
48
-
-
0028332850
-
Potential radioprotective agents. 1. Homologs of melatonin
-
Blickenstaff RT, Brandstadter SM, Reddy S et al. Potential radioprotective agents. 1. Homologs of melatonin. J Pharm Sci 1994;83:216-218.
-
(1994)
J Pharm Sci
, vol.83
, pp. 216-218
-
-
Blickenstaff, R.T.1
Brandstadter, S.M.2
Reddy, S.3
-
49
-
-
0033035371
-
Melatonin and protection from whole-body irradiation: Survival studies in mice
-
Vijayalaxmi, Meltz ML, Reiter RJ et al. Melatonin and protection from whole-body irradiation: Survival studies in mice. Mutat Res 1999;425: 21-27.
-
(1999)
Mutat Res
, vol.425
, pp. 21-27
-
-
Vijayalaxmi1
Meltz, M.L.2
Reiter, R.J.3
-
50
-
-
55349141421
-
Comparison of the protective effects of melatonin and amifostine on radiation-induced epiphyseal injury
-
Topkan E, Tufan H, Yavuz AA et al. Comparison of the protective effects of melatonin and amifostine on radiation-induced epiphyseal injury. Int J Radiat Biol 2008;84:796-802.
-
(2008)
Int J Radiat Biol
, vol.84
, pp. 796-802
-
-
Topkan, E.1
Tufan, H.2
Yavuz, A.A.3
-
51
-
-
57149139038
-
Cranial irradiation-induced inhibition of neurogenesis in hippocampal dentate gyrus of adult mice: Attenuation by melatonin pretreatment
-
Manda K, Ueno M, Anzai K. Cranial irradiation-induced inhibition of neurogenesis in hippocampal dentate gyrus of adult mice: Attenuation by melatonin pretreatment. J Pineal Res 2009;46:71-78.
-
(2009)
J Pineal Res
, vol.46
, pp. 71-78
-
-
Manda, K.1
Ueno, M.2
Anzai, K.3
-
52
-
-
54049094703
-
Melatonin and roentgen irradiation-induced acute radiation enteritis in Albino rats: An animal model
-
Hussein MR, Abu-Dief EE, Kamel E et al. Melatonin and roentgen irradiation-induced acute radiation enteritis in Albino rats: An animal model. Cell Biol Int 2008;32:1353-1361.
-
(2008)
Cell Biol Int
, vol.32
, pp. 1353-1361
-
-
Hussein, M.R.1
Abu-Dief, E.E.2
Kamel, E.3
-
53
-
-
34247346067
-
Melatonin attenuates radiation-induced learning deficit and brain oxidative stress in mice
-
Manda K, Anzai K, Kumari S et al. Melatonin attenuates radiation-induced learning deficit and brain oxidative stress in mice. Acta Neurobiol Exp (Wars) 2007;67:63-70.
-
(2007)
Acta Neurobiol Exp (Wars)
, vol.67
, pp. 63-70
-
-
Manda, K.1
Anzai, K.2
Kumari, S.3
-
54
-
-
0347758366
-
Chronopharmacology of melatonin in mice to maximize the antitumor effect and minimize the rhythm disturbance effect
-
Akagi T, Ushinohama K, Ikesue S et al. Chronopharmacology of melatonin in mice to maximize the antitumor effect and minimize the rhythm disturbance effect. J Pharmacol Exp Ther 2004;308:378-384.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 378-384
-
-
Akagi, T.1
Ushinohama, K.2
Ikesue, S.3
-
55
-
-
34249334847
-
Melatonin radiosensitizes tumors and radioprotects normal tissues: Time-of day dependency
-
Abstract 338
-
Blask DE, Barthold HJ, Dauchy RT et al. Melatonin radiosensitizes tumors and radioprotects normal tissues: Time-of day dependency. Am Assoc Cancer Res 2000.; Abstract 338.
-
(2000)
Am Assoc Cancer Res
-
-
Blask, D.E.1
Barthold, H.J.2
Dauchy, R.T.3
-
56
-
-
34249326606
-
Randomized phase II trial of high-dose melatonin and radiation therapy for RPA class 2 patients with brain metastases (RTOG 0119)
-
Berk L, Berkey B, Rich T et al. Randomized phase II trial of high-dose melatonin and radiation therapy for RPA class 2 patients with brain metastases (RTOG 0119). Int J Radiat Oncol Biol Phys 2007;68:852-857.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.68
, pp. 852-857
-
-
Berk, L.1
Berkey, B.2
Rich, T.3
-
57
-
-
42049095095
-
An agonist of Toll-like receptor 5 has radioprotective activity in mouse and primate models
-
Burdelya LG, Krivokrysenko VI, Tallant TC et al. An agonist of Toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 2008;320:226-230.
-
(2008)
Science
, vol.320
, pp. 226-230
-
-
Burdelya, L.G.1
Krivokrysenko, V.I.2
Tallant, T.C.3
-
58
-
-
33746161021
-
Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c lamina propria cells
-
Uematsu S, Jang MH, Chevrier N et al. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c lamina propria cells. Nat Immunol 2006;7:868-874.
-
(2006)
Nat Immunol
, vol.7
, pp. 868-874
-
-
Uematsu, S.1
Jang, M.H.2
Chevrier, N.3
-
59
-
-
1842423819
-
Human intestinal microvascular endothelial cells express Toll-like receptor 5: A binding partner for bacterial flagellin
-
Maaser C, Heidemann J, von Eiff C et al. Human intestinal microvascular endothelial cells express Toll-like receptor 5: A binding partner for bacterial flagellin. J Immunol 2004;172:5056-5062.
-
(2004)
J Immunol
, vol.172
, pp. 5056-5062
-
-
Maaser, C.1
Heidemann, J.2
von Eiff, C.3
-
60
-
-
4344669657
-
Activation of nuclear factor kappaB in vivo selectively protects the murine small intestine against ionizing radiation-induced damage
-
Wang Y, Meng A, Lang H et al. Activation of nuclear factor kappaB in vivo selectively protects the murine small intestine against ionizing radiation-induced damage. Cancer Res 2004;64:6240-6246.
-
(2004)
Cancer Res
, vol.64
, pp. 6240-6246
-
-
Wang, Y.1
Meng, A.2
Lang, H.3
-
61
-
-
33747826874
-
Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology
-
Bentzen SM. Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology. Nat Rev Cancer 2006;6:702-713.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 702-713
-
-
Bentzen, S.M.1
-
62
-
-
77951748771
-
-
ClinicalTrials.gov, Accessed January 12
-
ClinicalTrials.gov. Vol 2008. Accessed January 12, 2009.
-
(2009)
, vol.2008
-
-
-
63
-
-
0031829088
-
The radioprotective effect of BBI is associated with the activation of DNA repair-relevant genes
-
Dittmann KH, Gueven N, Mayer C et al. The radioprotective effect of BBI is associated with the activation of DNA repair-relevant genes. Int J Radiat Biol 1998;74:225-230.
-
(1998)
Int J Radiat Biol
, vol.74
, pp. 225-230
-
-
Dittmann, K.H.1
Gueven, N.2
Mayer, C.3
-
64
-
-
0344553306
-
Bowman-Birk protease inhibitor activates DNA-dependent protein kinase and reduces formation of radiation-induced dicentric chromosomes
-
Dittmann K, Virsik-Köpp P, Mayer C et al. Bowman-Birk protease inhibitor activates DNA-dependent protein kinase and reduces formation of radiation-induced dicentric chromosomes. Int J Radiat Biol 2003;79:801-808.
-
(2003)
Int J Radiat Biol
, vol.79
, pp. 801-808
-
-
Dittmann, K.1
Virsik-Köpp, P.2
Mayer, C.3
-
65
-
-
40249091300
-
The radioprotector Bowman-Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport
-
Dittmann K, Mayer C, Kehlbach R et al. The radioprotector Bowman-Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport. Radiother Oncol 2008;86: 375-382.
-
(2008)
Radiother Oncol
, vol.86
, pp. 375-382
-
-
Dittmann, K.1
Mayer, C.2
Kehlbach, R.3
-
66
-
-
44849121345
-
Effects of dietary antioxidant supplementation on the development of malignant lymphoma and other neoplastic lesions in mice exposed to proton or iron-ion radiation
-
Kennedy AR, Davis JG, Carlton W et al. Effects of dietary antioxidant supplementation on the development of malignant lymphoma and other neoplastic lesions in mice exposed to proton or iron-ion radiation. Radiat Res 2008;169:615-625.
-
(2008)
Radiat Res
, vol.169
, pp. 615-625
-
-
Kennedy, A.R.1
Davis, J.G.2
Carlton, W.3
-
67
-
-
17044370493
-
Selective radioprotection of normal tissues by Bowman-Birk proteinase inhibitor (BBI) in mice
-
Dittmann K, Toulany M, Classen J et al. Selective radioprotection of normal tissues by Bowman-Birk proteinase inhibitor (BBI) in mice. Strahlenther Onkol 2005;181:191-196.
-
(2005)
Strahlenther Onkol
, vol.181
, pp. 191-196
-
-
Dittmann, K.1
Toulany, M.2
Classen, J.3
-
68
-
-
0032525031
-
In vivo radioprotective effects of oltipraz in gamma-irradiated mice
-
Kim SG, Nam SY, Kim CW. In vivo radioprotective effects of oltipraz in gamma-irradiated mice. Biochem Pharmacol 1998;55:1585-1590.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1585-1590
-
-
Kim, S.G.1
Nam, S.Y.2
Kim, C.W.3
-
69
-
-
33947512453
-
Future strategies for mitigation and treatment of chronic radiation-induced normal tissue injury
-
Moulder JE, Cohen EP. Future strategies for mitigation and treatment of chronic radiation-induced normal tissue injury. Semin Radiat Oncol 2007; 17:141-148.
-
(2007)
Semin Radiat Oncol
, vol.17
, pp. 141-148
-
-
Moulder, J.E.1
Cohen, E.P.2
-
70
-
-
0029902158
-
Angiotensin II receptor antagonists in the prevention of radiation nephropathy
-
Moulder JE, Fish BL, Cohen EP et al. Angiotensin II receptor antagonists in the prevention of radiation nephropathy. Radiat Res 1996;146:106-110.
-
(1996)
Radiat Res
, vol.146
, pp. 106-110
-
-
Moulder, J.E.1
Fish, B.L.2
Cohen, E.P.3
-
71
-
-
1642580869
-
Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat
-
Kim JH, Brown SL, Kolozsvary A et al. Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat. Radiat Res 2004;161:137-142.
-
(2004)
Radiat Res
, vol.161
, pp. 137-142
-
-
Kim, J.H.1
Brown, S.L.2
Kolozsvary, A.3
-
72
-
-
0026554287
-
Radiation pneumotoxicity in rats: Modification by inhibitors of angiotensin converting enzyme
-
Ward WF, Molteni A, Ts'ao CH et al. Radiation pneumotoxicity in rats: Modification by inhibitors of angiotensin converting enzyme. Int J Radiat Oncol Biol Phys 1992;22:623-625.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.22
, pp. 623-625
-
-
Ward, W.F.1
Molteni, A.2
Ts'ao, C.H.3
-
73
-
-
0028000264
-
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils
-
Yousefi S, Green DR, Blaser K et al. Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc Natl Acad Sci USA 1994;91:10868-10872.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10868-10872
-
-
Yousefi, S.1
Green, D.R.2
Blaser, K.3
-
74
-
-
0345328280
-
Genistein treatment protects mice from ionizing radiation injury
-
Landauer MR, Srinivasan V, Seed TM. Genistein treatment protects mice from ionizing radiation injury. J Appl Toxicol 2003;23:379-385.
-
(2003)
J Appl Toxicol
, vol.23
, pp. 379-385
-
-
Landauer, M.R.1
Srinivasan, V.2
Seed, T.M.3
-
75
-
-
34848906040
-
Pravastatin inhibits the Rho/CCN2/ extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats
-
Haydont V, Bourgier C, Pocard M et al. Pravastatin inhibits the Rho/CCN2/ extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats. Clin Cancer Res 2007;13:5331-5340.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5331-5340
-
-
Haydont, V.1
Bourgier, C.2
Pocard, M.3
-
76
-
-
34547429997
-
Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism
-
Wang J, Boerma M, Fu Q et al. Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int J Radiat Oncol Biol Phys 2007;68:1483-1490.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.68
, pp. 1483-1490
-
-
Wang, J.1
Boerma, M.2
Fu, Q.3
-
77
-
-
3042763035
-
Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model
-
Williams JP, Hernady E, Johnston CJ et al. Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model. Radiat Res 2004;161:560-567.
-
(2004)
Radiat Res
, vol.161
, pp. 560-567
-
-
Williams, J.P.1
Hernady, E.2
Johnston, C.J.3
-
78
-
-
4344609471
-
Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair
-
Finch PW, Rubin JS. Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair. Adv Cancer Res 2004;91:69-136.
-
(2004)
Adv Cancer Res
, vol.91
, pp. 69-136
-
-
Finch, P.W.1
Rubin, J.S.2
-
79
-
-
55049129802
-
Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/ progenitor pool
-
Lombaert IM, Brunsting JF, Wierenga PK et al. Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/ progenitor pool. STEM CELLS 2008;26:2595-2601.
-
(2008)
STEM CELLS
, vol.26
, pp. 2595-2601
-
-
Lombaert, I.M.1
Brunsting, J.F.2
Wierenga, P.K.3
-
80
-
-
33750432886
-
Radiation therapy-induced mucositis: Relationships between fractionated radiation, NF-kappaB, COX-1, and COX-2
-
Yeoh A, Gibson R, Yeoh E et al. Radiation therapy-induced mucositis: Relationships between fractionated radiation, NF-kappaB, COX-1, and COX-2. Cancer Treat Rev 2006;32:645-651.
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 645-651
-
-
Yeoh, A.1
Gibson, R.2
Yeoh, E.3
-
81
-
-
27144462431
-
COX-2 inhibitors act as radiosensitizer in tumor treatment
-
Sminia P, Kuipers G, Geldof A et al. COX-2 inhibitors act as radiosensitizer in tumor treatment. Biomed Pharmacother 2005;59(suppl 2):S272-S275.
-
(2005)
Biomed Pharmacother
, vol.59
, Issue.SUPPL. 2
-
-
Sminia, P.1
Kuipers, G.2
Geldof, A.3
-
82
-
-
35348956422
-
Non-steroidal anti-inflammatory drugs in cancer prevention and therapy
-
Guadagni F, Ferroni P, Palmirotta R et al. Non-steroidal anti-inflammatory drugs in cancer prevention and therapy. Anticancer Res 2007;27:3147-3162.
-
(2007)
Anticancer Res
, vol.27
, pp. 3147-3162
-
-
Guadagni, F.1
Ferroni, P.2
Palmirotta, R.3
-
83
-
-
25844497528
-
Comparison of autologous cell therapy and granulocyte-colony stimulating factor (G-CSF) injection vs. G-CSF injection alone for the treatment of acute radiation syndrome in a non-human primate model
-
Bertho JM, Frick J, Prat M et al. Comparison of autologous cell therapy and granulocyte-colony stimulating factor (G-CSF) injection vs. G-CSF injection alone for the treatment of acute radiation syndrome in a non-human primate model. Int J Radiat Oncol Biol Phys 2005;63:911-920.
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.63
, pp. 911-920
-
-
Bertho, J.M.1
Frick, J.2
Prat, M.3
-
84
-
-
0025015087
-
In vivo radioprotective effects of recombinant human granulocyte colony-stimulating factor in lethally irradiated mice
-
Uckun FM, Souza L, Waddick KG et al. In vivo radioprotective effects of recombinant human granulocyte colony-stimulating factor in lethally irradiated mice. Blood 1990;75:638-645.
-
(1990)
Blood
, vol.75
, pp. 638-645
-
-
Uckun, F.M.1
Souza, L.2
Waddick, K.G.3
-
85
-
-
0032979426
-
Effects of keratinocyte growth factor in the squamous epithelium of the upper aerodigestive tract of normal and irradiated mice
-
Farrell CL, Rex KL, Kaufman SA et al. Effects of keratinocyte growth factor in the squamous epithelium of the upper aerodigestive tract of normal and irradiated mice. Int J Radiat Biol 1999;75:609-620.
-
(1999)
Int J Radiat Biol
, vol.75
, pp. 609-620
-
-
Farrell, C.L.1
Rex, K.L.2
Kaufman, S.A.3
-
86
-
-
10344242939
-
Palifermin for oral mucositis after intensive therapy for hematologic cancers
-
Spielberger R, Stiff P, Bensinger W et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med 2004;351:2590-2598.
-
(2004)
N Engl J Med
, vol.351
, pp. 2590-2598
-
-
Spielberger, R.1
Stiff, P.2
Bensinger, W.3
-
87
-
-
45149120776
-
Phase II study of palifermin and concurrent chemoradiation in head and neck squamous cell carcinoma
-
Brizel DM, Murphy BA, Rosenthal DI et al. Phase II study of palifermin and concurrent chemoradiation in head and neck squamous cell carcinoma. J Clin Oncol 2008;26:2489-2496.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2489-2496
-
-
Brizel, D.M.1
Murphy, B.A.2
Rosenthal, D.I.3
-
88
-
-
44449179168
-
Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury
-
Anscher MS, Thrasher B, Zgonjanin L et al. Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury. Int J Radiat Oncol Biol Phys 2008;71:829-837.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, pp. 829-837
-
-
Anscher, M.S.1
Thrasher, B.2
Zgonjanin, L.3
-
89
-
-
33646919832
-
Antitransforming growth factor-beta antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation
-
Anscher MS, Thrasher B, Rabbani Z et al. Antitransforming growth factor-beta antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation. Int J Radiat Oncol Biol Phys 2006;65:876-881.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, pp. 876-881
-
-
Anscher, M.S.1
Thrasher, B.2
Rabbani, Z.3
-
90
-
-
2442481893
-
Amelioration of radiation-induced fibrosis: Inhibition of transforming growth factor-beta signaling by halofuginone
-
Xavier S, Piek E, Fujii M et al. Amelioration of radiation-induced fibrosis: Inhibition of transforming growth factor-beta signaling by halofuginone. J Biol Chem 2004;279:15167-15176.
-
(2004)
J Biol Chem
, vol.279
, pp. 15167-15176
-
-
Xavier, S.1
Piek, E.2
Fujii, M.3
-
91
-
-
47549090432
-
TGF in cancer
-
Massagué J. TGF in cancer. Cell 2008;134:215-230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massagué, J.1
-
92
-
-
33748568793
-
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction
-
Baum BJ, Zheng C, Cotrim AP et al. Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction. Biochim Biophys Acta 2006;1758:1071-1077.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1071-1077
-
-
Baum, B.J.1
Zheng, C.2
Cotrim, A.P.3
|