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Volumn 9, Issue 3, 2012, Pages 278-289

Low-dose radiation stimulates Wnt/β-catenin signaling, neural stem cell proliferation and neurogenesis of the mouse hippocampus in vitro and in vivo

Author keywords

Alzheimer's disease; Hippocampus; Low dose radiation; Neurogenesis; Wnt signaling

Indexed keywords

BETA CATENIN; BROXURIDINE; NESTIN; WNT PROTEIN; WNT1 PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN;

EID: 84860285299     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/156720512800107627     Document Type: Article
Times cited : (57)

References (47)
  • 1
    • 0033306418 scopus 로고    scopus 로고
    • Restoring production of hippocampal neurons in old age
    • Cameron HA, McKay R. Restoring production of hippocampal neurons in old age. Nat Neurosci 2: 894-897 (1999).
    • (1999) Nat Neurosci , vol.2 , pp. 894-897
    • Cameron, H.A.1    McKay, R.2
  • 2
    • 0035833068 scopus 로고    scopus 로고
    • Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
    • Cameron HA, McKay RD. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 435:406-417 (2001).
    • (2001) J Comp Neurol , vol.435 , pp. 406-417
    • Cameron, H.A.1    McKay, R.D.2
  • 3
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
    • Kuhn HG, Dickinson-Anson H, Gage FH. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 16: 2027-2033 (1996).
    • (1996) J Neurosci , vol.16 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 4
    • 48149105674 scopus 로고    scopus 로고
    • Neurons born in the adult dentate gyrus form functional synapses with target cells
    • Toni N, Laplagne DA, Zhao C, Lombardi G, Ribak CE, Gage FH, et al. Neurons born in the adult dentate gyrus form functional synapses with target cells. Nat Neurosci 11:901-907 (2008).
    • (2008) Nat Neurosci , vol.11 , pp. 901-907
    • Toni, N.1    Laplagne, D.A.2    Zhao, C.3    Lombardi, G.4    Ribak, C.E.5    Gage, F.H.6
  • 5
    • 0033528813 scopus 로고    scopus 로고
    • Astrocytes reexpress nestin in deafferented target territories of the adult rat hippocampus
    • Brook GA, Perez-Bouza A, Noth J, Nacimiento W. Astrocytes reexpress nestin in deafferented target territories of the adult rat hippocampus. Neuroreport 10:1007-1011 (1999).
    • (1999) Neuroreport , vol.10 , pp. 1007-1011
    • Brook, G.A.1    Perez-Bouza, A.2    Noth, J.3    Nacimiento, W.4
  • 6
    • 0038354525 scopus 로고    scopus 로고
    • Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes
    • Filippov V, Kronenberg G, Pivneva T, Reuter K, Steiner B, Wang LP, et al. Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Mol Cell Neurosci 23:373-382 (2003).
    • (2003) Mol Cell Neurosci , vol.23 , pp. 373-382
    • Filippov, V.1    Kronenberg, G.2    Pivneva, T.3    Reuter, K.4    Steiner, B.5    Wang, L.P.6
  • 7
    • 0036890471 scopus 로고    scopus 로고
    • Enhancement of nestin proteinimmunoreactivity induced by ionizing radiation in the forebrain ependymal regions of rats
    • Shi M, Wei LC, Cao R, Chen LW. Enhancement of nestin proteinimmunoreactivity induced by ionizing radiation in the forebrain ependymal regions of rats. Neurosci Res 44:475-481 (2002).
    • (2002) Neurosci Res , vol.44 , pp. 475-481
    • Shi, M.1    Wei, L.C.2    Cao, R.3    Chen, L.W.4
  • 8
    • 0037111421 scopus 로고    scopus 로고
    • Nestin protein-containing cells express astrocytic glial fibrillary acidic protein in the proliferative regions of central nervous system of postnatal developing and adult mice
    • Wei LC, Shi M, Chen LW, Cao R, Zhang P, Chan YS. Nestin protein-containing cells express astrocytic glial fibrillary acidic protein in the proliferative regions of central nervous system of postnatal developing and adult mice. Brain Res Dev Brain Res 139:9-17 (2002).
    • (2002) Brain Res Dev Brain Res , vol.139 , pp. 9-17
    • Wei, L.C.1    Shi, M.2    Chen, L.W.3    Cao, R.4    Zhang, P.5    Chan, Y.S.6
  • 9
    • 0242363167 scopus 로고    scopus 로고
    • Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a
    • Castelo-Branco G, Wagner J, Rodriguez FJ, Kele J, Sousa K, Rawal N, et al. Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci USA 100:12747-12752 (2003).
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12747-12752
    • Castelo-Branco, G.1    Wagner, J.2    Rodriguez, F.J.3    Kele, J.4    Sousa, K.5    Rawal, N.6
  • 10
    • 32244442041 scopus 로고    scopus 로고
    • Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion
    • Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E. Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol Cell Neurosci 31:251-262 (2006).
    • (2006) Mol Cell Neurosci , vol.31 , pp. 251-262
    • Castelo-Branco, G.1    Sousa, K.M.2    Bryja, V.3    Pinto, L.4    Wagner, J.5    Arenas, E.6
  • 11
    • 33646812237 scopus 로고    scopus 로고
    • Function of Wnts in dopaminergic neuron development
    • Castelo-Branco G, Arenas E. Function of Wnts in dopaminergic neuron development. Neurodegener Dis 3:5-11 (2006).
    • (2006) Neurodegener Dis , vol.3 , pp. 5-11
    • Castelo-Branco, G.1    Arenas, E.2
  • 13
    • 3242889925 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells
    • Hirabayashi Y, Itoh Y, Tabata H, Nakajima K, Akiyama T, Masuyama N, et al. The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 131:2791-2801 (2004).
    • (2004) Development , vol.131 , pp. 2791-2801
    • Hirabayashi, Y.1    Itoh, Y.2    Tabata, H.3    Nakajima, K.4    Akiyama, T.5    Masuyama, N.6
  • 14
    • 35348900147 scopus 로고    scopus 로고
    • A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus
    • Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, et al. A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Dev Biol 311:223-237 (2007).
    • (2007) Dev Biol , vol.311 , pp. 223-237
    • Machon, O.1    Backman, M.2    Machonova, O.3    Kozmik, Z.4    Vacik, T.5    Andersen, L.6
  • 15
    • 34347407620 scopus 로고    scopus 로고
    • Wnt signal regulates stem cell fate and differentiation in vivo
    • Prakash N, Wurst WA. Wnt signal regulates stem cell fate and differentiation in vivo. Neurodegener Dis 4:333-338 (2007).
    • (2007) Neurodegener Dis , vol.4 , pp. 333-338
    • Prakash, N.1    Wurst, W.A.2
  • 17
    • 0037220599 scopus 로고    scopus 로고
    • Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
    • De Ferrari GV, Chacón MA, Barría MI, Garrido JL, Godoy JA, Olivares G, et al. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol Psychiatry 8:195-208 (2003).
    • (2003) Mol Psychiatry , vol.8 , pp. 195-208
    • de Ferrari, G.V.1    Chacón, M.A.2    Barría, M.I.3    Garrido, J.L.4    Godoy, J.A.5    Olivares, G.6
  • 18
    • 37249092445 scopus 로고    scopus 로고
    • Radiation effects on neural precursor cells in the dentate gyrus
    • Andres-Mach M, Rola R, Fike JR. Radiation effects on neural precursor cells in the dentate gyrus. Cell Tissue Res 331:251-262 (2008).
    • (2008) Cell Tissue Res , vol.331 , pp. 251-262
    • Andres-Mach, M.1    Rola, R.2    Fike, J.R.3
  • 19
    • 36949022049 scopus 로고    scopus 로고
    • Reversible effect of Xirradiation on proliferation, neurogenesis, and cell death in the dentate gyrus of adult mice
    • Ben Abdallah NM, Slomianka L, Lipp HP. Reversible effect of Xirradiation on proliferation, neurogenesis, and cell death in the dentate gyrus of adult mice. Hippocampus 17:1230-1240 (2007).
    • (2007) Hippocampus , vol.17 , pp. 1230-1240
    • Ben Abdallah, N.M.1    Slomianka, L.2    Lipp, H.P.3
  • 20
    • 33846518931 scopus 로고    scopus 로고
    • Radiation response of neural precursor cells
    • Fike JR, Rola R, Limoli CL. Radiation response of neural precursor cells. Neurosurg Clin N Am 18:115-127 (2007).
    • (2007) Neurosurg Clin N Am , vol.18 , pp. 115-127
    • Fike, J.R.1    Rola, R.2    Limoli, C.L.3
  • 21
    • 65249116981 scopus 로고    scopus 로고
    • Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation
    • Hellström NA, Björk-Eriksson T, Blomgren K, Kuhn HG. Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation. Stem Cells 27: 634-641 (2009).
    • (2009) Stem Cells , vol.27 , pp. 634-641
    • Hellström, N.A.1    Björk-Eriksson, T.2    Blomgren, K.3    Kuhn, H.G.4
  • 22
    • 0037396768 scopus 로고    scopus 로고
    • Radiation injury and neurogenesis
    • Monje ML and Palmer T. Radiation injury and neurogenesis. Curr Opin Neurol 16:129-134 (2003).
    • (2003) Curr Opin Neurol , vol.16 , pp. 129-134
    • Monje, M.L.1    Palmer, T.2
  • 23
    • 61649088370 scopus 로고    scopus 로고
    • NMDA receptor antagonist memantine promotes cell proliferation and production of mature granule neurons in the adult hippocampus
    • Maekawa M, Namba T, Suzuki E, Yuasa S, Kohsaka S, Uchino S. NMDA receptor antagonist memantine promotes cell proliferation and production of mature granule neurons in the adult hippocampus. Neurosci Res 63:259-266 (2009).
    • (2009) Neurosci Res , vol.63 , pp. 259-266
    • Maekawa, M.1    Namba, T.2    Suzuki, E.3    Yuasa, S.4    Kohsaka, S.5    Uchino, S.6
  • 24
    • 69449084425 scopus 로고    scopus 로고
    • The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus
    • Namba T, Maekawa M, Yuasa S, Kohsaka S, Uchino S. The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus. Glia 57:1082-1090 (2009).
    • (2009) Glia , vol.57 , pp. 1082-1090
    • Namba, T.1    Maekawa, M.2    Yuasa, S.3    Kohsaka, S.4    Uchino, S.5
  • 25
  • 26
    • 14044276801 scopus 로고    scopus 로고
    • Evidence for beneficial low level radiation effects and radiation hormesis
    • Feinendegen LE. Evidence for beneficial low level radiation effects and radiation hormesis. Br J Radiol 78:3-7 (2005).
    • (2005) Br J Radiol , vol.78 , pp. 3-7
    • Feinendegen, L.E.1
  • 27
    • 33745240967 scopus 로고    scopus 로고
    • Low dose radiation overcomes diabetes-induced suppression of hippocampal neuronal cell proliferation in rats
    • Kang JO, Kim SK, Hong SE, Lee TH, Kim CJ. Low dose radiation overcomes diabetes-induced suppression of hippocampal neuronal cell proliferation in rats. J Korean Med Sci 21:500-505 (2006).
    • (2006) J Korean Med Sci , vol.21 , pp. 500-505
    • Kang, J.O.1    Kim, S.K.2    Hong, S.E.3    Lee, T.H.4    Kim, C.J.5
  • 28
    • 52249094171 scopus 로고    scopus 로고
    • Transient impairment of hippocampus-dependent learning and memory in relatively low-dose of acute radiation syndrome is associated with inhibition of hippocampal neurogenesis
    • Kim JS, Lee HJ, Kim JC, Kang SS, Bae CS, Shin T, et al. Transient impairment of hippocampus-dependent learning and memory in relatively low-dose of acute radiation syndrome is associated with inhibition of hippocampal neurogenesis. J Radiat Res 49:517-526 (2008).
    • (2008) J Radiat Res , vol.49 , pp. 517-526
    • Kim, J.S.1    Lee, H.J.2    Kim, J.C.3    Kang, S.S.4    Bae, C.S.5    Shin, T.6
  • 29
    • 0347995022 scopus 로고    scopus 로고
    • Radiation response of neural precursor cells: Linking cellular sensitivity to cell cycle checkpoints, apoptosis and oxidative stress
    • Limoli CL, Giedzinski E, Rola R, Otsuka S, Palmer TD, Fike JR. Radiation response of neural precursor cells: linking cellular sensitivity to cell cycle checkpoints, apoptosis and oxidative stress. Radiat Res 161:17-27 (2004).
    • (2004) Radiat Res , vol.161 , pp. 17-27
    • Limoli, C.L.1    Giedzinski, E.2    Rola, R.3    Otsuka, S.4    Palmer, T.D.5    Fike, J.R.6
  • 30
    • 53749104127 scopus 로고    scopus 로고
    • Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: Ameliorative potential of the melatonin metabolite AFMK
    • Manda K, Ueno M, Anzai K. Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite AFMK. J Pineal Res 45:430-438 (2008).
    • (2008) J Pineal Res , vol.45 , pp. 430-438
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 32
    • 55449130378 scopus 로고    scopus 로고
    • Cranial radiation therapy and damage to hippocampal neurogenesis
    • Monje M. Cranial radiation therapy and damage to hippocampal neurogenesis. Dev Disabil Res Rev 14:238-242 (2008).
    • (2008) Dev Disabil Res Rev , vol.14 , pp. 238-242
    • Monje, M.1
  • 33
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje ML, Mizumatsu S, Fike JR, Palmer TD. Irradiation induces neural precursor-cell dysfunction. Nat Med 8:955-962 (2002).
    • (2002) Nat Med , vol.8 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 34
    • 0009711059 scopus 로고    scopus 로고
    • Ionizing radiationinduced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus
    • Peissner W, Kocher M, Treuer H, Gillardon F. Ionizing radiationinduced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus. Mol Brain Res 71:61-68 (1999).
    • (1999) Mol Brain Res , vol.71 , pp. 61-68
    • Peissner, W.1    Kocher, M.2    Treuer, H.3    Gillardon, F.4
  • 35
    • 1442329310 scopus 로고    scopus 로고
    • Irradiation attenuates neurogenesis and exacerbates ischemiainduced deficits
    • Raber J, Fan Y, Matsumori Y, Liu Z, Weinstein PR, Fike JR, et al. Irradiation attenuates neurogenesis and exacerbates ischemiainduced deficits. Ann Neurol 55:381-389 (2004).
    • (2004) Ann Neurol , vol.55 , pp. 381-389
    • Raber, J.1    Fan, Y.2    Matsumori, Y.3    Liu, Z.4    Weinstein, P.R.5    Fike, J.R.6
  • 36
    • 0037196872 scopus 로고    scopus 로고
    • The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis
    • Kee N, Sivalingam S, Boonstra R, Wojtowicz JM. The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis. J Neurosci Methods 115:97-105 (2002).
    • (2002) J Neurosci Methods , vol.115 , pp. 97-105
    • Kee, N.1    Sivalingam, S.2    Boonstra, R.3    Wojtowicz, J.M.4
  • 37
    • 0242391951 scopus 로고    scopus 로고
    • Chronic electroconvulsive seizure up-regulates beta-catenin expression in rat hippocampus: Role in adult neurogenesis
    • Madsen TM, Newton SS, Eaton ME, Russell DS, Duman RS. Chronic electroconvulsive seizure up-regulates beta-catenin expression in rat hippocampus: role in adult neurogenesis. Biol Psychiatry 54:1006-1014 (2003).
    • (2003) Biol Psychiatry , vol.54 , pp. 1006-1014
    • Madsen, T.M.1    Newton, S.S.2    Eaton, M.E.3    Russell, D.S.4    Duman, R.S.5
  • 38
    • 45849085732 scopus 로고    scopus 로고
    • A role for nuclear beta-catenin in SNRI antidepressant-induced hippocampal cell proliferation
    • Mostany R, Valdizán EM, Pazos A. A role for nuclear beta-catenin in SNRI antidepressant-induced hippocampal cell proliferation. Neuropharmacology 55:18-26 (2008).
    • (2008) Neuropharmacology , vol.55 , pp. 18-26
    • Mostany, R.1    Valdizán, E.M.2    Pazos, A.3
  • 39
    • 33645100156 scopus 로고    scopus 로고
    • Irradiation as an experimental tool in studies of adult neurogenesis
    • Wojtowicz JM. Irradiation as an experimental tool in studies of adult neurogenesis. Hippocampus 16:261-266 (2006).
    • (2006) Hippocampus , vol.16 , pp. 261-266
    • Wojtowicz, J.M.1
  • 40
    • 39449117350 scopus 로고    scopus 로고
    • Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation
    • Wexler EM, Geschwind DH, Palmer TD. Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation. Mol Psychiatry 13:285-292 (2008).
    • (2008) Mol Psychiatry , vol.13 , pp. 285-292
    • Wexler, E.M.1    Geschwind, D.H.2    Palmer, T.D.3
  • 41
    • 24944494556 scopus 로고    scopus 로고
    • Wnt signaling through canonical and non-canonical pathways: Recent progress
    • Widelitz R. Wnt signaling through canonical and non-canonical pathways: recent progress. Growth Factors 23:111-116 (2005).
    • (2005) Growth Factors , vol.23 , pp. 111-116
    • Widelitz, R.1
  • 42
    • 69549083403 scopus 로고    scopus 로고
    • Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons
    • Tang M, Miyamoto Y, Huang EJ. Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons. Development 136:2027-2038 (2009).
    • (2009) Development , vol.136 , pp. 2027-2038
    • Tang, M.1    Miyamoto, Y.2    Huang, E.J.3
  • 43
    • 38149126482 scopus 로고    scopus 로고
    • Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice
    • Parish CL, Castelo-Branco G, Rawal N, Tonnesen J, Sorensen AT, Salto C, et al. Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. J Clin Invest 118:149-160 (2008).
    • (2008) J Clin Invest , vol.118 , pp. 149-160
    • Parish, C.L.1    Castelo-Branco, G.2    Rawal, N.3    Tonnesen, J.4    Sorensen, A.T.5    Salto, C.6
  • 44
    • 77954497673 scopus 로고    scopus 로고
    • Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons
    • Tang M, Villaescusa JC, Luo SX, Guitarte C, Lei S, Miyamoto Y, et al. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci 30:9280-9291 (2010).
    • (2010) J Neurosci , vol.30 , pp. 9280-9291
    • Tang, M.1    Villaescusa, J.C.2    Luo, S.X.3    Guitarte, C.4    Lei, S.5    Miyamoto, Y.6
  • 47
    • 69349096036 scopus 로고    scopus 로고
    • Exposure to low-dose ionizing radiation from medical imaging procedures
    • Fazel R, Krumholz HM, Wang Y, Ross JS, Chen J, Ting HH, et al. Exposure to low-dose ionizing radiation from medical imaging procedures. N Engl J Med 361:849-857 (2009).
    • (2009) N Engl J Med , vol.361 , pp. 849-857
    • Fazel, R.1    Krumholz, H.M.2    Wang, Y.3    Ross, J.S.4    Chen, J.5    Ting, H.H.6


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