-
1
-
-
0032575694
-
Stroke-damaged neurons may commit cellular suicide
-
BARINAGA, M. (1998). Stroke-damaged neurons may commit cellular suicide. Science 281, 1302-1303.
-
(1998)
Science
, vol.281
, pp. 1302-1303
-
-
Barinaga, M.1
-
2
-
-
13344260700
-
A newly defined interleukin-1?
-
BAZAN, J., TIMANS, J. C. & KASTLELEIN, R. A. (1996). A newly defined interleukin-1? Nature 379, 591.
-
(1996)
Nature
, vol.379
, pp. 591
-
-
Bazan, J.1
Timans, J.C.2
Kastlelein, R.A.3
-
3
-
-
0026513065
-
Cytokines: Influence on glial cell gene expression and function
-
BENEVISTE, E. N. (1992). Cytokines: influence on glial cell gene expression and function. Neuroimmunoendocrinology 52, 106-153.
-
(1992)
Neuroimmunoendocrinology
, vol.52
, pp. 106-153
-
-
Beneviste, E.N.1
-
4
-
-
0029836252
-
Interleukin-1 in cerebral ischaemia
-
BETZ, K., SCHIELKE, G. P. & YANG, G.-Y. (1996). Interleukin-1 in cerebral ischaemia. Keio Journal of Medicine 45, 230-238.
-
(1996)
Keio Journal of Medicine
, vol.45
, pp. 230-238
-
-
Betz, K.1
Schielke, G.P.2
Yang, G.-Y.3
-
5
-
-
0029035825
-
Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain
-
BETZ, A. L., YANG, G.-Y. & DAVIDSON, B. L. (1995). Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. Journal of Cerebral Blood Flow and Metabolism 15, 547-551.
-
(1995)
Journal of Cerebral Blood Flow and Metabolism
, vol.15
, pp. 547-551
-
-
Betz, A.L.1
Yang, G.-Y.2
Davidson, B.L.3
-
6
-
-
0024405827
-
The biology of cachectin/TNF-α: A primary mediator of the host response
-
BEUTLER, B. & CERAMI, A. (1989). The biology of cachectin/TNF-α: a primary mediator of the host response. Annual Review of Immunology 7, 625-655.
-
(1989)
Annual Review of Immunology
, vol.7
, pp. 625-655
-
-
Beutler, B.1
Cerami, A.2
-
7
-
-
8944259908
-
Increased expression of IL-1beta converting enzyme in hippocampus after ischemia: Selective localization in microglia
-
BHAT, R. V., DIROCCO, R., MARCY, V. R., FLOOD, D. G., ZHU, Y., DOBRZANSKI, P., SIMAN, R., SCOTT, R., CONTRERAS, P. C. & MILLER, M. (1996). Increased expression of IL-1beta converting enzyme in hippocampus after ischemia: selective localization in microglia. Journal of Neuroscience 16, 4146-4154.
-
(1996)
Journal of Neuroscience
, vol.16
, pp. 4146-4154
-
-
Bhat, R.V.1
Dirocco, R.2
Marcy, V.R.3
Flood, D.G.4
Zhu, Y.5
Dobrzanski, P.6
Siman, R.7
Scott, R.8
Contreras, P.C.9
Miller, M.10
-
8
-
-
0345682317
-
Evidence for different interleukin-1 receptors in murine B-and T-cell lines
-
BOMSZTYK, K., SIMS, J. K., STANTON, T. H., SLACK, J., MCMAHAN, C. J., VALENTINE, M. A. & DOWER, S. K. (1989). Evidence for different interleukin-1 receptors in murine B-and T-cell lines. Proceedings of the National Academy of Sciences of the USA 86, 8034-8038.
-
(1989)
Proceedings of the National Academy of Sciences of the USA
, vol.86
, pp. 8034-8038
-
-
Bomsztyk, K.1
Sims, J.K.2
Stanton, T.H.3
Slack, J.4
McMahan, C.J.5
Valentine, M.A.6
Dower, S.K.7
-
9
-
-
0030863114
-
Mechanisms of neuronal cell injury/death and targets for drug intervention
-
BOXER, P. A. & BIGGE, C. F. (1997). Mechanisms of neuronal cell injury/death and targets for drug intervention. Drug Discovery Today 2, 219-228.
-
(1997)
Drug Discovery Today
, vol.2
, pp. 219-228
-
-
Boxer, P.A.1
Bigge, C.F.2
-
10
-
-
0028176793
-
Induction of interleukin-1 beta messenger RXA after focal cerebral ischaemia in the rat
-
BUTTINI, M., SAUTER, A. & BODDEKE, H. W. G. M. (1994). Induction of interleukin-1 beta messenger RXA after focal cerebral ischaemia in the rat. Molecular Brain Research 23, 126-134.
-
(1994)
Molecular Brain Research
, vol.23
, pp. 126-134
-
-
Buttini, M.1
Sauter, A.2
Boddeke, H.W.G.M.3
-
11
-
-
0026517239
-
Molecular cloning of the interleukin-1β converting enzyme
-
CERRETTI, D. P., KOZLOSKY, C. J., MOSLEY, B., NELSON, N., VAN NESS, K. V., GREENSTREET, T. A., MARCH, C. J., KRONHEIM, S. R., DRUCK, T., CANNIZZARO, L. A., HUEBNER, K. & BLACK, R. A. (1992). Molecular cloning of the interleukin-1β converting enzyme. Science 256, 97-102.
-
(1992)
Science
, vol.256
, pp. 97-102
-
-
Cerretti, D.P.1
Kozlosky, C.J.2
Mosley, B.3
Nelson, N.4
Van Ness, K.V.5
Greenstreet, T.A.6
March, C.J.7
Kronheim, S.R.8
Druck, T.9
Cannizzaro, L.A.10
Huebner, K.11
Black, R.A.12
-
12
-
-
0030638547
-
Mechanisms of nerve cell death: Apoptosis or necrosis after cerebral ischaemia
-
ed. GREEN, A. R. & CROSS, A. J., Academic Press, New York
-
CHALMERS-REDMAN, R. M. E., FRASER, A. D., Ju, W. Y. H., WADIA, J., TATTON, N. A. & TATTON, W. G. (1997). Mechanisms of nerve cell death: apoptosis or necrosis after cerebral ischaemia. In Neuroprotective Agents and Cerebral Ischaemia, ed. GREEN, A. R. & CROSS, A. J., pp. 1-25. Academic Press, New York.
-
(1997)
Neuroprotective Agents and Cerebral Ischaemia
, pp. 1-25
-
-
Chalmers-Redman, R.M.E.1
Fraser, A.D.2
Ju, W.Y.H.3
Wadia, J.4
Tatton, N.A.5
Tatton, W.G.6
-
13
-
-
0029620390
-
Interleukin-1 and tumour necrosis factor-alpha synergistically mediate neurotoxicity: Involvement of nitric oxide and of N-methyl-D-aspartate receptors
-
CHAO, C. C., HU, S., EHRLICH, L. & PETERSON, P. K. (1995). Interleukin-1 and tumour necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors. Brain Behaviour and Immunology 9, 355-365.
-
(1995)
Brain Behaviour and Immunology
, vol.9
, pp. 355-365
-
-
Chao, C.C.1
Hu, S.2
Ehrlich, L.3
Peterson, P.K.4
-
14
-
-
0030108525
-
Cytokine-stimulated astrocytes damage human neurones via a nitric oxide mechanism
-
CHAO, C. C., HU, S., SHENG, W. S., BU, D., BUKRINSKY, M. I. & PETERSON, P. K. (1996). Cytokine-stimulated astrocytes damage human neurones via a nitric oxide mechanism. Glia 16, 276-284.
-
(1996)
Glia
, vol.16
, pp. 276-284
-
-
Chao, C.C.1
Hu, S.2
Sheng, W.S.3
Bu, D.4
Bukrinsky, M.I.5
Peterson, P.K.6
-
15
-
-
0027197996
-
Neuroprotective role of IL-4 against activated microglia
-
CHAO, C. C., MOLITOR, T. W. & HU, S. (1993). Neuroprotective role of IL-4 against activated microglia. Journal of Immunology 151, 1473-1481.
-
(1993)
Journal of Immunology
, vol.151
, pp. 1473-1481
-
-
Chao, C.C.1
Molitor, T.W.2
Hu, S.3
-
16
-
-
0032080673
-
Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxicischemic brain injury
-
CHENG, Y., DESHMUKH, M., D'COSTA, A., DEMARO, J. A., GIDDAY, J. M., SHAH, A., SUN, Y., JACQUIN, M. K., JOHNSON, E. M. & HOLTZMAN, D. M. (1998). Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxicischemic brain injury. Journal of Clinical Investigation 101, 1992-1999.
-
(1998)
Journal of Clinical Investigation
, vol.101
, pp. 1992-1999
-
-
Cheng, Y.1
Deshmukh, M.2
D'Costa, A.3
Demaro, J.A.4
Gidday, J.M.5
Shah, A.6
Sun, Y.7
Jacquin, M.K.8
Johnson, E.M.9
Holtzman, D.M.10
-
17
-
-
0027181936
-
Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
-
COLOTTA, F., RE, F., MUZIO, M., BERTINI, B., POLENTARUTTI, N., SIRONI, M., GIRI, J. G., DOWER, S. K., SIMS, J. E. & MANTOVANI, A. (1993). Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 261, 472-475.
-
(1993)
Science
, vol.261
, pp. 472-475
-
-
Colotta, F.1
Re, F.2
Muzio, M.3
Bertini, B.4
Polentarutti, N.5
Sironi, M.6
Giri, J.G.7
Dower, S.K.8
Sims, J.E.9
Mantovani, A.10
-
18
-
-
0030820712
-
Inhibition of NMDA receptor-mediated synaptic transmission in the rat dentate gyms in vitro by IL-1β
-
COOGAN, A. & O'CONNOR, J. J. (1997). Inhibition of NMDA receptor-mediated synaptic transmission in the rat dentate gyms in vitro by IL-1β. NeuroReport 8, 2107-2110.
-
(1997)
NeuroReport
, vol.8
, pp. 2107-2110
-
-
Coogan, A.1
O'Connor, J.J.2
-
19
-
-
0031820520
-
Cloning of rat brain interleukin-18 cDNA
-
CULHANE, A. C., HALL, M D., ROTHWELL, N. J. & LUHESHI, G. N. (1998). Cloning of rat brain interleukin-18 cDNA. Molecular Psychiatry 3, 362-366.
-
(1998)
Molecular Psychiatry
, vol.3
, pp. 362-366
-
-
Culhane, A.C.1
Hall, M.D.2
Rothwell, N.J.3
Luheshi, G.N.4
-
20
-
-
0026582456
-
In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary and adrenal gland of the mouse
-
CUNNINGHAM, E., WADA, K., CARTER, D., TRACEY, D., BATTEY, J. & DE SOUZA, E. (1992). In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary and adrenal gland of the mouse. Journal of Neuroscience 12, 1101-1114.
-
(1992)
Journal of Neuroscience
, vol.12
, pp. 1101-1114
-
-
Cunningham, E.1
Wada, K.2
Carter, D.3
Tracey, D.4
Battey, J.5
De Souza, E.6
-
21
-
-
0344317646
-
The progression and topographic distribution of interleukine-1β expression after permanent middle cerebral artery occlusion in the rat
-
in the Press
-
DAVIES, C. A., LODDICK, S. A., TOULMOND, S., STROEMER, R. P., HUNT, J. & ROTHWELL, N. J. (1998). The progression and topographic distribution of interleukine-1β expression after permanent middle cerebral artery occlusion in the rat. Journal of Cerebral Blood Flow and Metabolism (in the Press).
-
(1998)
Journal of Cerebral Blood Flow and Metabolism
-
-
Davies, C.A.1
Loddick, S.A.2
Toulmond, S.3
Stroemer, R.P.4
Hunt, J.5
Rothwell, N.J.6
-
22
-
-
0025777448
-
Interleukin-1 and interleukin-1 antagonism
-
DINARELLO, C. A. (1991). Interleukin-1 and interleukin-1 antagonism. Blood 77, 1627-1652.
-
(1991)
Blood
, vol.77
, pp. 1627-1652
-
-
Dinarello, C.A.1
-
23
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
DINARELLO, C. A. (1996). Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
24
-
-
0031831906
-
Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
-
DINARELLO, C. A. (1998). Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. International Review of Immunology 16, 457-499.
-
(1998)
International Review of Immunology
, vol.16
, pp. 457-499
-
-
Dinarello, C.A.1
-
25
-
-
0031749136
-
Overview of interleukin-18: More than an interferon-γ inducing factor
-
DINARELLO, C. A., NOVICK, D., PUREN, A. J., FANTUZZI, G., SHAPIRO, L., MUHL, H., YOON, D.-Y., REZNIKOV, L. L., KIM, S.-H. & RUBINSTEIN, M. (1998). Overview of interleukin-18: more than an interferon-γ inducing factor. Journal of Leukocyte Biology 63, 658-664.
-
(1998)
Journal of Leukocyte Biology
, vol.63
, pp. 658-664
-
-
Dinarello, C.A.1
Novick, D.2
Puren, A.J.3
Fantuzzi, G.4
Shapiro, L.5
Muhl, H.6
Yoon, D.-Y.7
Reznikov, L.L.8
Kim, S.-H.9
Rubinstein, M.10
-
26
-
-
0026056197
-
Blocking IL-1: Interleukin 1 receptor antagonist in vivo and in vitro
-
DINARELLO, C. A. & THOMPSON, R. C. (1991). Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro. Immunology Today 12, 404-410.
-
(1991)
Immunology Today
, vol.12
, pp. 404-410
-
-
Dinarello, C.A.1
Thompson, R.C.2
-
27
-
-
0029085982
-
Excitatory amino acid receptors and neurodegeneration
-
DOBLE, A. (1995). Excitatory amino acid receptors and neurodegeneration. Therapie 50, 319-337.
-
(1995)
Therapie
, vol.50
, pp. 319-337
-
-
Doble, A.1
-
28
-
-
0031892704
-
Attenuation of delayed neuronal death after mild focal ischaemia in mice by inhibition of the caspase family
-
ENDRES, M., NAMURA, S., SHIMIZU-SASAMATA, M., WAEBER, C., ZHANO, L., GOMEZ-ISLA, T., HYMAN, B. T. & MOSKOWITZ, M. A. (1998). Attenuation of delayed neuronal death after mild focal ischaemia in mice by inhibition of the caspase family. Journal of Cerebral Blood Flow and Metabolism 18, 238-247.
-
(1998)
Journal of Cerebral Blood Flow and Metabolism
, vol.18
, pp. 238-247
-
-
Endres, M.1
Namura, S.2
Shimizu-Sasamata, M.3
Waeber, C.4
Zhano, L.5
Gomez-Isla, T.6
Hyman, B.T.7
Moskowitz, M.A.8
-
29
-
-
0028885890
-
Type 1 interleukin1 receptor in the rat brain: Distribution, regulation, and relationship to sites of IL-1-induced cellular activation
-
ERICSSON, A., LIU, C., HART, R. P. & SAWCHENKO, P. E. (1995). Type 1 interleukin1 receptor in the rat brain: distribution, regulation, and relationship to sites of IL-1-induced cellular activation. Journal of Comparative Neurology 261, 681-698.
-
(1995)
Journal of Comparative Neurology
, vol.261
, pp. 681-698
-
-
Ericsson, A.1
Liu, C.2
Hart, R.P.3
Sawchenko, P.E.4
-
30
-
-
8044252166
-
Expression of a dominant negative mutant of interleukin-1β converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischaemic brain injury
-
FRIEDLANDER, R. M., GAGLIARDINI, V., HARA, H., FINK, K. B., LI, W., MACDONALD, G., FISHMAN, M. C., GREENBERRY, A. H., MOSKOWITZ, M. A. & YAN, Y. (1997). Expression of a dominant negative mutant of interleukin-1β converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischaemic brain injury. Journal of Experimental Medicine 185, 933-940.
-
(1997)
Journal of Experimental Medicine
, vol.185
, pp. 933-940
-
-
Friedlander, R.M.1
Gagliardini, V.2
Hara, H.3
Fink, K.B.4
Li, W.5
Macdonald, G.6
Fishman, M.C.7
Greenberry, A.H.8
Moskowitz, M.A.9
Yan, Y.10
-
31
-
-
0029788702
-
Functional role of interleukin-1β (IL-1) in IL-1β converting enzyme mediated apoptosis
-
FRIEDLANDER, R. M., GAGLIARDINI, V., ROTELLO, R. J. & YUAN, J. (1996). Functional role of interleukin-1β (IL-1) in IL-1β converting enzyme mediated apoptosis. Journal of Experimental Medicine 184, 717-724.
-
(1996)
Journal of Experimental Medicine
, vol.184
, pp. 717-724
-
-
Friedlander, R.M.1
Gagliardini, V.2
Rotello, R.J.3
Yuan, J.4
-
32
-
-
0028790262
-
Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion
-
GARCIA, J. H., LIU, K.-F. & RELTON, J. K. (1995). Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion. American Journal of Pathology 147, 1477-1486.
-
(1995)
American Journal of Pathology
, vol.147
, pp. 1477-1486
-
-
Garcia, J.H.1
Liu, K.-F.2
Relton, J.K.3
-
33
-
-
0019217369
-
Anorexia and cancer in animals and man
-
GARRATTINI, S., BIZZ, A., DONELLI, M. G., GUAITANI, A., SAMANIN, R. & SPREAFICO, F. (1980). Anorexia and cancer in animals and man. Cancer Treatment Reviews 7, 115-139.
-
(1980)
Cancer Treatment Reviews
, vol.7
, pp. 115-139
-
-
Garrattini, S.1
Bizz, A.2
Donelli, M.G.3
Guaitani, A.4
Samanin, R.5
Spreafico, F.6
-
34
-
-
0027463358
-
Brain glia release factors with opposing actions upon neuronal survival
-
GIULIAN, D., VACA, K. & CORPUZ, M. (1993). Brain glia release factors with opposing actions upon neuronal survival. Journal of Neuroscience 13, 29-37.
-
(1993)
Journal of Neuroscience
, vol.13
, pp. 29-37
-
-
Giulian, D.1
Vaca, K.2
Corpuz, M.3
-
35
-
-
0029009910
-
Molecular cloning and characterisation of a second subunit of the interleukin-1 receptor complex
-
GREENFEDER, S. A., NUNES, P., KWEE, L., LABOW, M., CHIZZONITE, R. A. & JU, G. (1995). Molecular cloning and characterisation of a second subunit of the interleukin-1 receptor complex. Journal of Biological Chemistry 270, 13757-13765.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 13757-13765
-
-
Greenfeder, S.A.1
Nunes, P.2
Kwee, L.3
Labow, M.4
Chizzonite, R.A.5
Ju, G.6
-
36
-
-
15644369352
-
Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme
-
GU, Y., KUIDA, K., TSUTSUI, H., KU, G., HSIAO, K., FLEMING, M. A., HAYASHI, N., HIGASHINO, K., OKAMUKA, H., NAKANISKI, K., KURIMOTO, M., TANIMOTO, T., FLAVELL, R. A., SATO, V., HARDING, M. W., LIVINGSTONE, D. J. & SU, M. S. S. (1997). Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme. Science 275, 206-209.
-
(1997)
Science
, vol.275
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
Ku, G.4
Hsiao, K.5
Fleming, M.A.6
Hayashi, N.7
Higashino, K.8
Okamuka, H.9
Nakaniski, K.10
Kurimoto, M.11
Tanimoto, T.12
Flavell, R.A.13
Sato, V.14
Harding, M.W.15
Livingstone, D.J.16
Su, M.S.S.17
-
37
-
-
0028556463
-
Blood-borne interleukin-1 receptor antagonist crosses the blood brain barrier
-
GUTIERREZ, E. G., BANKS, W. A. & KASTIN, A. J. (1994). Blood-borne interleukin-1 receptor antagonist crosses the blood brain barrier. Journal of Neuroimmunology 55, 153-160.
-
(1994)
Journal of Neuroimmunology
, vol.55
, pp. 153-160
-
-
Gutierrez, E.G.1
Banks, W.A.2
Kastin, A.J.3
-
38
-
-
0030614952
-
Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
-
HARA, H., FRIEDLANDER, R. M., GAGLIARDINI, V., AYATA, C., FINK, K., HUANG, Z., SHIMIZU-SASAMATA, M., YUAN, J. & MOSKOWITZ, M. A. (1997). Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proceedings of the National Academy of Sciences of the USA 94, 2007-2012.
-
(1997)
Proceedings of the National Academy of Sciences of the USA
, vol.94
, pp. 2007-2012
-
-
Hara, H.1
Friedlander, R.M.2
Gagliardini, V.3
Ayata, C.4
Fink, K.5
Huang, Z.6
Shimizu-Sasamata, M.7
Yuan, J.8
Moskowitz, M.A.9
-
39
-
-
0024358775
-
Recombinant interleukin-1β stimulates eieosanoid production in rat primary culture astrocytes
-
HARTUNG, H.-P., SCHAFER, B., HEININGER, K. & TOYKA, K. V. (1989). Recombinant interleukin-1β stimulates eieosanoid production in rat primary culture astrocytes. Brain Research 489, 113-118.
-
(1989)
Brain Research
, vol.489
, pp. 113-118
-
-
Hartung, H.-P.1
Schafer, B.2
Heininger, K.3
Toyka, K.V.4
-
40
-
-
0029664296
-
ICE family proteases: Mediators of apoptotic cell death?
-
HENKART, P. A. (1996). ICE family proteases: mediators of apoptotic cell death? Immunity 4, 195-201.
-
(1996)
Immunity
, vol.4
, pp. 195-201
-
-
Henkart, P.A.1
-
41
-
-
0030756576
-
Caspases: A treatment target for neurodegenerative diseases?
-
HOLTZMAN, D. M. & DESHMUKH, M. (1997). Caspases: A treatment target for neurodegenerative diseases? Nature Medicine 3, 954-955.
-
(1997)
Nature Medicine
, vol.3
, pp. 954-955
-
-
Holtzman, D.M.1
Deshmukh, M.2
-
42
-
-
0028800715
-
Cytokines in the nervous system I: Expression and recognition
-
HOPKINS, S. J. & ROTHWELL, N. J. (1995). Cytokines in the nervous system I: Expression and recognition. Trends in Neurosciences 18, 83-88.
-
(1995)
Trends in Neurosciences
, vol.18
, pp. 83-88
-
-
Hopkins, S.J.1
Rothwell, N.J.2
-
43
-
-
0029140838
-
Cytokine modulation of murine microglial cell superoxide production
-
HU, S., SHENG, W. S., PETERSON, P. K. & CHAO, C. C. (1995). Cytokine modulation of murine microglial cell superoxide production. Glia 13, 45-50.
-
(1995)
Glia
, vol.13
, pp. 45-50
-
-
Hu, S.1
Sheng, W.S.2
Peterson, P.K.3
Chao, C.C.4
-
44
-
-
0030662372
-
Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein
-
HUANG, J., GAO, X., LI, S. & CAO, Z. (1997). Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. Proceedings of the National Academy of Sciences of the USA 94, 12829-12832.
-
(1997)
Proceedings of the National Academy of Sciences of the USA
, vol.94
, pp. 12829-12832
-
-
Huang, J.1
Gao, X.2
Li, S.3
Cao, Z.4
-
45
-
-
0000045760
-
Interleukin-1β in focal cerebral ischaemia in rats
-
IANOTTI, K., KIDA, S., WELLER, R., BUHAGIER, G. & HILLHOUSE, E. (1993). Interleukin-1β in focal cerebral ischaemia in rats. Journal of Cerebral Blood Flow and Metabolism 13, s125.
-
(1993)
Journal of Cerebral Blood Flow and Metabolism
, vol.13
-
-
Ianotti, K.1
Kida, S.2
Weller, R.3
Buhagier, G.4
Hillhouse, E.5
-
47
-
-
0031595870
-
Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
-
LAWRENCE, C. B., ALLAN, S. M. & ROTHWELL, N. J. (1998). Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. European Journal of Neuroscience 10, 1188-1195.
-
(1998)
European Journal of Neuroscience
, vol.10
, pp. 1188-1195
-
-
Lawrence, C.B.1
Allan, S.M.2
Rothwell, N.J.3
-
48
-
-
0027422993
-
Induction of nitric oxide synthase activity in human astrocytes by interleukin-1α and interferon-γ
-
LEE, S. C., DICKSON, D. C., LIU, W. & BROSNAN, C. F. (1993). Induction of nitric oxide synthase activity in human astrocytes by interleukin-1α and interferon-γ. Journal of Neuroimmunology 46, 19-23.
-
(1993)
Journal of Neuroimmunology
, vol.46
, pp. 19-23
-
-
Lee, S.C.1
Dickson, D.C.2
Liu, W.3
Brosnan, C.F.4
-
49
-
-
0029036329
-
Interleukin-1 receptor antagonist attenuates the heat stroke-induced neuronal damage by reducing the cerebral ischemia in rats
-
LIN, M. T., KAO, T. Y., JIN, Y. T. & CHEN, C. F. (1995). Interleukin-1 receptor antagonist attenuates the heat stroke-induced neuronal damage by reducing the cerebral ischemia in rats. Brain Research 37, 595-598.
-
(1995)
Brain Research
, vol.37
, pp. 595-598
-
-
Lin, M.T.1
Kao, T.Y.2
Jin, Y.T.3
Chen, C.F.4
-
50
-
-
0028930295
-
Programmed cell death in cerebral ischaemia
-
LINNICK, M. D. (1995). Programmed cell death in cerebral ischaemia. CNS Drugs 3, 239-244.
-
(1995)
CNS Drugs
, vol.3
, pp. 239-244
-
-
Linnick, M.D.1
-
51
-
-
0027436533
-
Interleukin-1 beta mRNA expression in ischaemic rat cortex
-
LIU, T., MCDONNELL, P. C., YOUNG, P. R., WHITE, R. F., SIREN, A. L., HALLENBECK, J. M., BARONE, F. C. & FEUERSTEIN, G. Z. (1993). Interleukin-1 beta mRNA expression in ischaemic rat cortex. Stroke 24, 1746-1751.
-
(1993)
Stroke
, vol.24
, pp. 1746-1751
-
-
Liu, T.1
McDonnell, P.C.2
Young, P.R.3
White, R.F.4
Siren, A.L.5
Hallenbeck, J.M.6
Barone, F.C.7
Feuerstein, G.Z.8
-
52
-
-
0032079085
-
Interleukin-1 receptors: Cloning studies and role in central nervous system disorders
-
LODDICK, S. A., LIU, C., TAKAO, T., HASHIMOTO, K. & DE SOUZA, E. B. (1998). Interleukin-1 receptors: cloning studies and role in central nervous system disorders. Brain Research Reviews 26, 306-319.
-
(1998)
Brain Research Reviews
, vol.26
, pp. 306-319
-
-
Loddick, S.A.1
Liu, C.2
Takao, T.3
Hashimoto, K.4
De Souza, E.B.5
-
53
-
-
0029773397
-
An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat
-
LODDICK, S. A., MACKENZIE, A. & ROTHWELL, N. J. (1996). An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. NeuroReport 7, 1465-1468.
-
(1996)
NeuroReport
, vol.7
, pp. 1465-1468
-
-
Loddick, S.A.1
Mackenzie, A.2
Rothwell, N.J.3
-
54
-
-
0029744418
-
Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat
-
LODDICK, S. A. & ROTHWELL, N. J. (1996). Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. Journal of Cerebral Blood Flow and Metabolism 16, 932-940.
-
(1996)
Journal of Cerebral Blood Flow and Metabolism
, vol.16
, pp. 932-940
-
-
Loddick, S.A.1
Rothwell, N.J.2
-
55
-
-
0031894808
-
Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischaemia in the rat
-
LODDICK, S. A., TURNBULL, A. V. & ROTHWELL, N. J. (1998). Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischaemia in the rat. Journal of Cerebral Blood Flow and Metabolism 18, 176-179.
-
(1998)
Journal of Cerebral Blood Flow and Metabolism
, vol.18
, pp. 176-179
-
-
Loddick, S.A.1
Turnbull, A.V.2
Rothwell, N.J.3
-
56
-
-
0030957283
-
Endogenous interleukin-1 receptor antagonist is neuroprotective
-
LODDICK, S. A., WONG, M.-L., BONGIORNO, P. B., GOLD, P. W., LICINIO, J. & ROTHWELL, N. J. (1997). Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochemical and Biophysical Research Communications 234, 211-215.
-
(1997)
Biochemical and Biophysical Research Communications
, vol.234
, pp. 211-215
-
-
Loddick, S.A.1
Wong, M.-L.2
Bongiorno, P.B.3
Gold, P.W.4
Licinio, J.5
Rothwell, N.J.6
-
57
-
-
0030298213
-
Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL-1R-rp2)
-
LOVENBERG, T. W., CROWE, P. D., LIU, C., CHALMERS, D. T., LIU, X. J., LIAW, C., CLEVENGER, W., OLTERSDORF, T., DE SOUZA, E. B. & MAKI, R. A. (1996). Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL-1R-rp2). Journal of Neuroimmunology 70, 113-122.
-
(1996)
Journal of Neuroimmunology
, vol.70
, pp. 113-122
-
-
Lovenberg, T.W.1
Crowe, P.D.2
Liu, C.3
Chalmers, D.T.4
Liu, X.J.5
Liaw, C.6
Clevenger, W.7
Oltersdorf, T.8
De Souza, E.B.9
Maki, R.A.10
-
58
-
-
0027482617
-
Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat
-
LUHESHI, G., HOPKINS, S. J., LEFEUVRE, R. A., DASCOMBE, M. J., GHIARA, P. & ROTHWELL, N. J. (1993). Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat. American Journal of Physiology 265, 585-591.
-
(1993)
American Journal of Physiology
, vol.265
, pp. 585-591
-
-
Luheshi, G.1
Hopkins, S.J.2
Lefeuvre, R.A.3
Dascombe, M.J.4
Ghiara, P.5
Rothwell, N.J.6
-
59
-
-
0025865128
-
Corticotrophin-releasing factor antagonist reduces ischaemic hippocampal neuronal injury
-
LYONS, M. K., ANDERSON, R. E. & MEYER, F. B. (1991). Corticotrophin-releasing factor antagonist reduces ischaemic hippocampal neuronal injury. Brain Research 545, 339-342.
-
(1991)
Brain Research
, vol.545
, pp. 339-342
-
-
Lyons, M.K.1
Anderson, R.E.2
Meyer, F.B.3
-
60
-
-
0028630590
-
The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischaemia
-
MARTIN, D., CHINOOKOSWONG, N. & MILLER, G. (1995). The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischaemia. Experimental Neurology 130, 362-367.
-
(1995)
Experimental Neurology
, vol.130
, pp. 362-367
-
-
Martin, D.1
Chinookoswong, N.2
Miller, G.3
-
61
-
-
0030891270
-
The interleukin-1 receptor complex and interleukin-1 signal transduction
-
MARTIN, M. U. & FALK, W. (1997). The interleukin-1 receptor complex and interleukin-1 signal transduction. European Cytokine Network 8, 5-17.
-
(1997)
European Cytokine Network
, vol.8
, pp. 5-17
-
-
Martin, M.U.1
Falk, W.2
-
62
-
-
0028828583
-
Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats
-
MARTIN, D. & NEAR, S. L. (1995). Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats. Journal of Neuroimmunology 61, 241-245.
-
(1995)
Journal of Neuroimmunology
, vol.61
, pp. 241-245
-
-
Martin, D.1
Near, S.L.2
-
63
-
-
0344749966
-
Cytokines as therapeutic agents in neurological disorders
-
ed. ROTHWELL, N. J., Chapman & Hall, Boston
-
MARTIN, D., RELTON, J. K., MULLER, G., BENDELE, A., FISCHER, N. & RUSSELL, D. (1996). Cytokines as therapeutic agents in neurological disorders. In Cytokines in the Nervous System, ed. ROTHWELL, N. J., pp. 162-178. Chapman & Hall, Boston.
-
(1996)
Cytokines in the Nervous System
, pp. 162-178
-
-
Martin, D.1
Relton, J.K.2
Muller, G.3
Bendele, A.4
Fischer, N.5
Russell, D.6
-
64
-
-
0026530776
-
Induction of interleukin-1β mRNA in rat brain transient forebrain ischaemia
-
MINAMI, M., KURAISHI, K., YABUUCHI, K., YAMAZAKI, K. & SATOH, M. (1992). Induction of interleukin-1β mRNA in rat brain transient forebrain ischaemia. Journal of Neurochemistry 58, 390-392.
-
(1992)
Journal of Neurochemistry
, vol.58
, pp. 390-392
-
-
Minami, M.1
Kuraishi, K.2
Yabuuchi, K.3
Yamazaki, K.4
Satoh, M.5
-
65
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. Elegans cell death gene ced-3
-
MIURA, M., ZHU, H., ROTELLO, R., HARTWIEG, E. A. & YUAN, J. (1993). Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75, 653-660.
-
(1993)
Cell
, vol.75
, pp. 653-660
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
Hartwieg, E.A.4
Yuan, J.5
-
66
-
-
0024551090
-
Interleukin-1 and tumour necrosis factor stimulate vascular endothelial cells to promote transendothelial neutrophil passage
-
MOSER, R., SCHLEIFFENBAUM, B., GROSCURTH, P. & FEHR, J. (1989). Interleukin-1 and tumour necrosis factor stimulate vascular endothelial cells to promote transendothelial neutrophil passage. Journal of Clinical Investigation 83, 444-451.
-
(1989)
Journal of Clinical Investigation
, vol.83
, pp. 444-451
-
-
Moser, R.1
Schleiffenbaum, B.2
Groscurth, P.3
Fehr, J.4
-
68
-
-
0030239633
-
IL-4 induced expression of the IL-1 receptor antagonist gene is mediated by STAT6
-
OHMORI, Y., SMITH, M. F. & HAMILTON, T. A. (1996). IL-4 induced expression of the IL-1 receptor antagonist gene is mediated by STAT6. Journal of Immunology 57, 2058-2065.
-
(1996)
Journal of Immunology
, vol.57
, pp. 2058-2065
-
-
Ohmori, Y.1
Smith, M.F.2
Hamilton, T.A.3
-
69
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-gamma production by T-cells
-
OKAMURA, H., TSUTSUI, H., KOMATSU, T., YUTSUDO, M., HAKURA, A., TANIMOTO, T., TORIGOE, K., OKURA, T., NUKADA, Y. L., HATTORI, K., AKITA, K., NAMBA, M., TANABE, F., KONISHI, K., FUKUDA, S. & KURIMOTO, M. (1995). Cloning of a new cytokine that induces IFN-gamma production by T-cells. Nature 378, 88-91.
-
(1995)
Nature
, vol.378
, pp. 88-91
-
-
Okamura, H.1
Tsutsui, H.2
Komatsu, T.3
Yutsudo, M.4
Hakura, A.5
Tanimoto, T.6
Torigoe, K.7
Okura, T.8
Nukada, Y.L.9
Hattori, K.10
Akita, K.11
Namba, M.12
Tanabe, F.13
Konishi, K.14
Fukuda, S.15
Kurimoto, M.16
-
70
-
-
0030054290
-
Pharmacological targets in the immune response. Interleukin-1 receptors and signal transduction
-
O'NEILL, L. A. J. (1996). Pharmacological targets in the immune response. Interleukin-1 receptors and signal transduction. Biochemical Society Transactions 24, 207-211.
-
(1996)
Biochemical Society Transactions
, vol.24
, pp. 207-211
-
-
O'Neill, L.A.J.1
-
71
-
-
0032485016
-
The neuroproteetive effects of the recombinant interleukin-1 receptor antagonist rhIL-1ra after excitotoxic stimulation with kainic acid and its relationship to the amyloid precursor protein gene
-
PANEGYRES, P. K. & HUGHES, J. (1998). The neuroproteetive effects of the recombinant interleukin-1 receptor antagonist rhIL-1ra after excitotoxic stimulation with kainic acid and its relationship to the amyloid precursor protein gene. Journal of the Neurological Sciences 154, 123-132.
-
(1998)
Journal of the Neurological Sciences
, vol.154
, pp. 123-132
-
-
Panegyres, P.K.1
Hughes, J.2
-
72
-
-
0029989325
-
IL-1Rrp is a novel receptor like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP
-
PARNET, P., GARKA, K. E., BONNERT, T. P., DOWER, S. K. & SIMS, J. E. (1996). IL-1Rrp is a novel receptor like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP. Journal of Biological Chemistry 271, 3967-3970.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 3967-3970
-
-
Parnet, P.1
Garka, K.E.2
Bonnert, T.P.3
Dower, S.K.4
Sims, J.E.5
-
73
-
-
0345612093
-
Excitotoxic brain damage in the rat induces IL-1 protein in microglia and astrocytes: Correlation with the progression of cell death
-
in the Press
-
PEARSON, V., ROTHWELL, N. J. & TOULMOND, S. (1998). Excitotoxic brain damage in the rat induces IL-1 protein in microglia and astrocytes: correlation with the progression of cell death. Glia (in the Press).
-
(1998)
Glia
-
-
Pearson, V.1
Rothwell, N.J.2
Toulmond, S.3
-
74
-
-
0026767773
-
Interleukin-1β depresses calcium currents in CA1 hippocampal, neurones at pathophysiological concentrations
-
PLATA-SALAMAN, C. R. & FFRENCH-MULLEN, J. M. H. (1991). Interleukin-1β depresses calcium currents in CA1 hippocampal, neurones at pathophysiological concentrations. Brain Research Bulletin 29, 221-225.
-
(1991)
Brain Research Bulletin
, vol.29
, pp. 221-225
-
-
Plata-Salaman, C.R.1
Ffrench-Mullen, J.M.H.2
-
75
-
-
0025910921
-
Recombinant human interleukin-1 induces meningitis and blood-brain barrier injury in the rat. Characterization and comparison with tumor necrosis factor
-
QUAGLIARELLO, V. J., WISPELWEY, B., LONG, W. J. JR & SCHELD, W. M. (1991). Recombinant human interleukin-1 induces meningitis and blood-brain barrier injury in the rat. Characterization and comparison with tumor necrosis factor. Journal of Clinical Investigation 87, 1360-1366.
-
(1991)
Journal of Clinical Investigation
, vol.87
, pp. 1360-1366
-
-
Quagliarello, V.J.1
Wispelwey, B.2
Long W.J., Jr.3
Scheld, W.M.4
-
76
-
-
0031080252
-
A combinatorial approach for determining protease specificities; application to interleukin-1β converting enzyme (ICE)
-
RANO, T. A., TIMKEY, T., PETERSON, E. P., ROTONDA, J., NICHOLSON, D. W., BECKER, J. W., CHAPMAN, K. T. & THORNBERRY, N. A. (1997). A combinatorial approach for determining protease specificities; application to interleukin-1β converting enzyme (ICE). Chemistry and Biology 4, 149-155.
-
(1997)
Chemistry and Biology
, vol.4
, pp. 149-155
-
-
Rano, T.A.1
Timkey, T.2
Peterson, E.P.3
Rotonda, J.4
Nicholson, D.W.5
Becker, J.W.6
Chapman, K.T.7
Thornberry, N.A.8
-
77
-
-
0030800928
-
Controversies surrounding glucocorticoid-mediated cell death in the hippocampus
-
REAGAN, L. P. & MCEWEN, B. S. (1997). Controversies surrounding glucocorticoid-mediated cell death in the hippocampus. Journal of Chemical Neuroanatomy 13, 149-167.
-
(1997)
Journal of Chemical Neuroanatomy
, vol.13
, pp. 149-167
-
-
Reagan, L.P.1
McEwen, B.S.2
-
78
-
-
0029865092
-
Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat
-
RELTON, J. K., MARTIN, D., THOMPSON, R. C. & RUSSELL, D. A. (1996). Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat. Experimental Neurology 138, 206-213.
-
(1996)
Experimental Neurology
, vol.138
, pp. 206-213
-
-
Relton, J.K.1
Martin, D.2
Thompson, R.C.3
Russell, D.A.4
-
79
-
-
0026656192
-
Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat
-
RELTON, J. K. & ROTHWELL, N. J. (1992). Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Research Bulletin 29, 243-246.
-
(1992)
Brain Research Bulletin
, vol.29
, pp. 243-246
-
-
Relton, J.K.1
Rothwell, N.J.2
-
80
-
-
0025820423
-
Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain
-
RELTON, J. K., STRIJBOS, P. J. L. M., O'SHAUGHNESSY, C. T., CAREY, F., FORDER, R. A., TILDERS, F. J. H. & ROTHWELL, N. J. (1991). Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. Journal of Experimental Medicine 174, 305-310.
-
(1991)
Journal of Experimental Medicine
, vol.174
, pp. 305-310
-
-
Relton, J.K.1
Strijbos, P.J.L.M.2
O'Shaughnessy, C.T.3
Carey, F.4
Forder, R.A.5
Tilders, F.J.H.6
Rothwell, N.J.7
-
81
-
-
0026686234
-
Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats
-
RIDENOUR, T. R., WARNER, D. S., TODD, M. M. & MCALLISTER, A. C. (1992). Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats. Stroke 23, 733-738.
-
(1992)
Stroke
, vol.23
, pp. 733-738
-
-
Ridenour, T.R.1
Warner, D.S.2
Todd, M.M.3
McAllister, A.C.4
-
82
-
-
0031866288
-
Evidence for the involvement of corticotrophin releasing hormone (CRH) in the pathogenesis of traumatic brain injury
-
ROE, S. Y., MCGOWAN, E. M. & ROTHWELL, N. J. (1998). Evidence for the involvement of corticotrophin releasing hormone (CRH) in the pathogenesis of traumatic brain injury. European Journal of Neuroscience 10, 553-559.
-
(1998)
European Journal of Neuroscience
, vol.10
, pp. 553-559
-
-
Roe, S.Y.1
McGowan, E.M.2
Rothwell, N.J.3
-
83
-
-
0030998444
-
Neuroimmune interactions: The role of cytokines
-
ROTHWELL, N. J. (1997). Neuroimmune interactions: the role of cytokines. British Journal of Pharmacology 121, 841-847.
-
(1997)
British Journal of Pharmacology
, vol.121
, pp. 841-847
-
-
Rothwell, N.J.1
-
84
-
-
0031438499
-
Cytokines and the brain: The role of interleukin-1 in acute neurodegeneration and stroke: Pathophysiological and therapeutic implications
-
ROTHWELL, N. J., ALLAN, S. & TOULMOND, S. (1997). Cytokines and the brain: the role of interleukin-1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications. Journal of Clinical Investigation 100, 2648-2652.
-
(1997)
Journal of Clinical Investigation
, vol.100
, pp. 2648-2652
-
-
Rothwell, N.J.1
Allan, S.2
Toulmond, S.3
-
85
-
-
0026327741
-
Interleukin-6 is a centrally acting endogenous pyrogen in the rat
-
ROTHWELL, N. J., BUSBRIDGE, N. J., LEFEUVRE, R. A., HARDWICK, A. J., GAULDIE, J. & HOPKINS, S. J. (1991). Interleukin-6 is a centrally acting endogenous pyrogen in the rat. Canadian Journal of Physiology and Pharmacology 69, 1465-1469.
-
(1991)
Canadian Journal of Physiology and Pharmacology
, vol.69
, pp. 1465-1469
-
-
Rothwell, N.J.1
Busbridge, N.J.2
Lefeuvre, R.A.3
Hardwick, A.J.4
Gauldie, J.5
Hopkins, S.J.6
-
86
-
-
0026543542
-
Lipocortin-1 exhibits novel actions providing clinical opportunities
-
ROTHWELL, N. J. & FLOWER, R. (1992). Lipocortin-1 exhibits novel actions providing clinical opportunities. Trends in Pharmacological Sciences 13, 45-46.
-
(1992)
Trends in Pharmacological Sciences
, vol.13
, pp. 45-46
-
-
Rothwell, N.J.1
Flower, R.2
-
87
-
-
0028869476
-
Cytokines and the nervous system. II: Actions and mechanisms of action
-
ROTHWELL, N. J. & HOPKINS, S. J. (1995). Cytokines and the nervous system. II: Actions and mechanisms of action. Trends in Neurosciences 18, 130-136.
-
(1995)
Trends in Neurosciences
, vol.18
, pp. 130-136
-
-
Rothwell, N.J.1
Hopkins, S.J.2
-
88
-
-
8544220450
-
Interleukins and cerebral ischaemia
-
ed. GREEN, A. R. & CROSS, A. J., Academic Press, New York
-
ROTHVVELL, N. J., LODDICK, S. A. & STROEMER, P. (1996a). Interleukins and cerebral ischaemia. In Neuroprotective Agents and Cerebral Ischaemia, ed. GREEN, A. R. & CROSS, A. J., pp. 281-298. Academic Press, New York.
-
(1996)
Neuroprotective Agents and Cerebral Ischaemia
, pp. 281-298
-
-
Rothvvell, N.J.1
Loddick, S.A.2
Stroemer, P.3
-
89
-
-
0028317949
-
Pharmacology of interleukin-1 actions in the brain
-
ROTHWELL, N. J. & LUHESHI, G. N. (1994). Pharmacology of interleukin-1 actions in the brain. Advances in Pharmacology 25, 1-20.
-
(1994)
Advances in Pharmacology
, vol.25
, pp. 1-20
-
-
Rothwell, N.J.1
Luheshi, G.N.2
-
90
-
-
0029925745
-
Cytokines and their receptors in the central nervous system: Physiology, pharmacology and pathology
-
ROTHWELL, N. J., LUHESHI, G. & TOULMOND, S. (1996b). Cytokines and their receptors in the central nervous system: Physiology, pharmacology and pathology. Pharmacological Therapeutics 69, 85-95.
-
(1996)
Pharmacological Therapeutics
, vol.69
, pp. 85-95
-
-
Rothwell, N.J.1
Luheshi, G.2
Toulmond, S.3
-
91
-
-
0017948330
-
Mechanisms of weight gain and loss in reversible obesity in the rat
-
ROTHWELL, N. J. & STOCK, M. J. (1978). Mechanisms of weight gain and loss in reversible obesity in the rat. Journal of Physiology 276, 60-61P.
-
(1978)
Journal of Physiology
, vol.276
-
-
Rothwell, N.J.1
Stock, M.J.2
-
92
-
-
0000248516
-
Brown adipose tissue
-
ed. BAKER, P. F., Churchill Livingstone, Edinburgh
-
ROTHWELL, N. J. & STOCK, M. J. (1984). Brown adipose tissue. In Recent Advances in Physiology, vol. 10, ed. BAKER, P. F., pp. 349-384. Churchill Livingstone, Edinburgh.
-
(1984)
Recent Advances in Physiology
, vol.10
, pp. 349-384
-
-
Rothwell, N.J.1
Stock, M.J.2
-
93
-
-
0000305819
-
Brown adipose tissue and diet-induced thermogenesis
-
ed. TRAYHURN, P. & NICHOLLS, D. G., Edward Arnold, London
-
ROTHWELL, N. J. & STOCK, N. J. (1986). Brown adipose tissue and diet-induced thermogenesis. In Brown Adipose Tissue, ed. TRAYHURN, P. & NICHOLLS, D. G., pp. 269-298. Edward Arnold, London.
-
(1986)
Brown Adipose Tissue
, pp. 269-298
-
-
Rothwell, N.J.1
Stock, N.J.2
-
94
-
-
0344749957
-
Actions of IL-1 in neurodegeneration
-
ed. KRIEGELTEIN, J., Medpharm, Stuttgart
-
ROTHWELL, N. J., STROEMER, P., LAWRENCE, C. & DAVIES, C. (1996c). Actions of IL-1 in neurodegeneration. In Pharmacology of Cerebral Ischaemia, ed. KRIEGELTEIN, J., pp. 125-129. Medpharm, Stuttgart.
-
(1996)
Pharmacology of Cerebral Ischaemia
, pp. 125-129
-
-
Rothwell, N.J.1
Stroemer, P.2
Lawrence, C.3
Davies, C.4
-
95
-
-
0026518686
-
Alzheimer's disease: Pathology to potential treatments
-
ROYSTON, M. C., ROTHWELL, N. J. & ROBERTS, G. W. (1992). Alzheimer's disease: pathology to potential treatments. Trends in Pharmacological Sciences 13, 131-133.
-
(1992)
Trends in Pharmacological Sciences
, vol.13
, pp. 131-133
-
-
Royston, M.C.1
Rothwell, N.J.2
Roberts, G.W.3
-
96
-
-
0022345349
-
Glucocorticoids potentiate ischaemic injury to neurons: Therapeutic implications
-
SAPOLSKY, R. M. & PULSINELLI, W. A. (1985). Glucocorticoids potentiate ischaemic injury to neurons: therapeutic implications. Science 229, 1397-1399.
-
(1985)
Science
, vol.229
, pp. 1397-1399
-
-
Sapolsky, R.M.1
Pulsinelli, W.A.2
-
97
-
-
0031894316
-
Reduced ischaemic brain injury in interleukin-1 beta converting enzyme-deficient mice
-
SCHIELKE, G. P., YANG, G. Y., SHIVERS, B. D. & BETZ, A. L. (1998). Reduced ischaemic brain injury in interleukin-1 beta converting enzyme-deficient mice. Journal of Cerebral Blood Flow and Metabolism 18, 180-185.
-
(1998)
Journal of Cerebral Blood Flow and Metabolism
, vol.18
, pp. 180-185
-
-
Schielke, G.P.1
Yang, G.Y.2
Shivers, B.D.3
Betz, A.L.4
-
98
-
-
0007692414
-
In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis
-
SHENG, J. G., ITO, K., SKINNER, R. D., MRAK, R. E., ROVNAGHI, C. R., VAN ELDIK, L. & GRIFFIN, W. S. T. (1996). In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis. Neurobiology of Ageing 7, 761-766.
-
(1996)
Neurobiology of Ageing
, vol.7
, pp. 761-766
-
-
Sheng, J.G.1
Ito, K.2
Skinner, R.D.3
Mrak, R.E.4
Rovnaghi, C.R.5
Van Eldik, L.6
Griffin, W.S.T.7
-
99
-
-
0028351424
-
Regulation of intercellular adhesion molecule-1 gene expression by tumor necrosis factor-alpha, interleukin-1 beta, and interferon-gamma in astrocytes
-
SHRIKANT, P., CHUNG, I. Y., BALLESTAS, M. E. & BENVENISTE, E. N. (1994). Regulation of intercellular adhesion molecule-1 gene expression by tumor necrosis factor-alpha, interleukin-1 beta, and interferon-gamma in astrocytes. Journal of Neuroimmunology 51, 209-220.
-
(1994)
Journal of Neuroimmunology
, vol.51
, pp. 209-220
-
-
Shrikant, P.1
Chung, I.Y.2
Ballestas, M.E.3
Benveniste, E.N.4
-
100
-
-
0027236605
-
Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells
-
SIMMONS, M. L. & MURPHY, S. (1993). Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells. European Journal of Neuroscience 5, 825-832.
-
(1993)
European Journal of Neuroscience
, vol.5
, pp. 825-832
-
-
Simmons, M.L.1
Murphy, S.2
-
101
-
-
0027287950
-
Interleukin-1 signalling occurs exclusively via the type I receptor
-
SIMS, J., GAYLE, M. A., SLACK, J. L., ALDERSON, M. R., BIRD, T. A., GIRI, J. G., COLOTTA, F., RE, F., MANTOVANI, A., SHANEBECK, K., GRABSTEIN, K. H. & DOWER, S. K. (1993). Interleukin-1 signalling occurs exclusively via the type I receptor. Proceedings of the National Academy of Sciences of the USA 90, 6155-6159.
-
(1993)
Proceedings of the National Academy of Sciences of the USA
, vol.90
, pp. 6155-6159
-
-
Sims, J.1
Gayle, M.A.2
Slack, J.L.3
Alderson, M.R.4
Bird, T.A.5
Giri, J.G.6
Colotta, F.7
Re, F.8
Mantovani, A.9
Shanebeck, K.10
Grabstein, K.H.11
Dower, S.K.12
-
102
-
-
0032127873
-
IL-6 stimulates annexin-1 expression and translocation, and suggests a new biological role as class II acute phase protein
-
in the Press
-
SOLITO, E., DE COUPADE, C., PARENTE, L., FLOWER, R. J. & RUSSO-MARIE, F. (1998). IL-6 stimulates annexin-1 expression and translocation, and suggests a new biological role as class II acute phase protein. Cytokine (in the Press).
-
(1998)
Cytokine
-
-
Solito, E.1
De Coupade, C.2
Parente, L.3
Flower, R.J.4
Russo-Marie, F.5
-
103
-
-
0025073281
-
Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: Comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo
-
SPRANGER, M., LINDHOLM, D., BANDTLOW, C., HEUMANN, R., GHAHN, H., NÄHER-NOÉ, M. & THOENEN, H. (1990). Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo. European Journal of Neuroscience 2, 69-76.
-
(1990)
European Journal of Neuroscience
, vol.2
, pp. 69-76
-
-
Spranger, M.1
Lindholm, D.2
Bandtlow, C.3
Heumann, R.4
Ghahn, H.5
Näher-Noé, M.6
Thoenen, H.7
-
104
-
-
0028169562
-
Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebal ischaemia or activation of NMDA receptors in the rat brain
-
STRIJBOS, P. J. L. M., RELTON, J. K. & ROTHWELL, N. J. (1994). Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebal ischaemia or activation of NMDA receptors in the rat brain. Brain Research 656, 405-408.
-
(1994)
Brain Research
, vol.656
, pp. 405-408
-
-
Strijbos, P.J.L.M.1
Relton, J.K.2
Rothwell, N.J.3
-
105
-
-
0029047891
-
Interleukin-1β attenuates excitatory amino acid induced neurodegeneration in vitro: Involvement of nerve growth factor
-
STRIJBOS, P. J. L. M. & ROTHWELL, N. J. (1995). Interleukin-1β attenuates excitatory amino acid induced neurodegeneration in vitro: involvement of nerve growth factor. Journal of Neuroscience 15, 3468-3474.
-
(1995)
Journal of Neuroscience
, vol.15
, pp. 3468-3474
-
-
Strijbos, P.J.L.M.1
Rothwell, N.J.2
-
106
-
-
0030789773
-
Cortical protection by localised striatal injection of IL-1ra following cerebral ischaemia in the rat
-
STROEMER, R. P. & ROTHWELL, N. J. (1997). Cortical protection by localised striatal injection of IL-1ra following cerebral ischaemia in the rat. Journal of Cerebral Blood Flow and Metabolism 17, 597-604.
-
(1997)
Journal of Cerebral Blood Flow and Metabolism
, vol.17
, pp. 597-604
-
-
Stroemer, R.P.1
Rothwell, N.J.2
-
107
-
-
2542508161
-
Exacerbation of ischaemic brain damage by localised striatal injection of IL-1β in the rat
-
in the Press
-
STROEMER, R. P. & ROTHWELL, N. J. (1998). Exacerbation of ischaemic brain damage by localised striatal injection of IL-1β in the rat. Journal of Cerebral Blood Flow and Metabolism (in the Press).
-
(1998)
Journal of Cerebral Blood Flow and Metabolism
-
-
Stroemer, R.P.1
Rothwell, N.J.2
-
108
-
-
0024359491
-
Both recombinant interleukin-1 (beta) and purified human monocyte interleukin-1 prime human neutrophils for increased oxidative activity and promote neutrophil spreading
-
SULLIVAN, G. W., CARPER, H. T., SULLIVAN, J. A., MURATA, T. & MANDELL, G. L. (1989). Both recombinant interleukin-1 (beta) and purified human monocyte interleukin-1 prime human neutrophils for increased oxidative activity and promote neutrophil spreading. Journal of Leukocyte Biology 45, 389-395.
-
(1989)
Journal of Leukocyte Biology
, vol.45
, pp. 389-395
-
-
Sullivan, G.W.1
Carper, H.T.2
Sullivan, J.A.3
Murata, T.4
Mandell, G.L.5
-
109
-
-
0027400847
-
Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre-and post-traumatic treatment with R05 4864 a peripheral-type (p site) benzodiazepine ligand
-
TAUPIN, V., TOULMOND, S., SERRANO, A., BENAVIDES, J. & ZAVALA, F. (1993). Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre-and post-traumatic treatment with R05 4864 a peripheral-type (p site) benzodiazepine ligand. Journal of Neuroimmunology 42, 177-185.
-
(1993)
Journal of Neuroimmunology
, vol.42
, pp. 177-185
-
-
Taupin, V.1
Toulmond, S.2
Serrano, A.3
Benavides, J.4
Zavala, F.5
-
110
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
THORNBERRY, N. A., BULL, H. G., CALAYCAY, J. R., CHAPMAN, K. T., HOWARD, A. D., KOSTURA, M. J., MILLER, D. K., MOLINEAUX, S. M., WEIDNER, J. R., AUNINS, J., ELLISTAN, K. O., AYALA, J. M., CASANO, F. J., CHIN, J., DING, G. J.-F., EGGER, L. A., GAFFNEY, E. P., LIMJUCO, G., PALYHA, O. C., RAJU, S. M., ROLANDO, A. M., SALLEY, J. P., YANIN, T.-T., LEE, T. D., SHIVELY, J. E., MACCROSS, M., MUMFORD, R. A., SCHMIDT, J. A. & TOCCI, M. (1992). A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356, 768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
Ellistan, K.O.11
Ayala, J.M.12
Casano, F.J.13
Chin, J.14
Ding, G.J.-F.15
Egger, L.A.16
Gaffney, E.P.17
Limjuco, G.18
Palyha, O.C.19
Raju, S.M.20
Rolando, A.M.21
Salley, J.P.22
Yanin, T.-T.23
Lee, T.D.24
Shively, J.E.25
Maccross, M.26
Mumford, R.A.27
Schmidt, J.A.28
Tocci, M.29
more..
-
111
-
-
0031020503
-
Cancer cachexia: Metabolic alterations and clinical manifestations
-
TISDALE, M. J. (1997). Cancer cachexia: metabolic alterations and clinical manifestations. Nutrition 13, 1-7.
-
(1997)
Nutrition
, vol.13
, pp. 1-7
-
-
Tisdale, M.J.1
-
112
-
-
0030851728
-
Purification and characterisation of the human interleukin-18 receptor
-
TORIGOE, K., USHIO, S., OKURA, T., KOBAYASHI, S., TANIAI, M., KUNIKATA, T., MURAKAMI, T., SANOU, O., KOJIMA, H., FUJII, M., OHTA, T., IKEDA, M., IKEGAMI, H. & KURIMOTO, M. (1997). Purification and characterisation of the human interleukin-18 receptor. Journal of Biological Chemistry 272, 25737-25742.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 25737-25742
-
-
Torigoe, K.1
Ushio, S.2
Okura, T.3
Kobayashi, S.4
Taniai, M.5
Kunikata, T.6
Murakami, T.7
Sanou, O.8
Kojima, H.9
Fujii, M.10
Ohta, T.11
Ikeda, M.12
Ikegami, H.13
Kurimoto, M.14
-
113
-
-
0028982742
-
Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat
-
TOULMOND, S. & ROTHWELL, N. J. (1995a). Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat. Brain Research 671, 261-266.
-
(1995)
Brain Research
, vol.671
, pp. 261-266
-
-
Toulmond, S.1
Rothwell, N.J.2
-
114
-
-
0010449687
-
Time course of IL-1 receptor antagonist (IL-1ra) expression after brain trauma in the rat
-
TOULMOND, S. & ROTHWELL, N. J. (1956). Time course of IL-1 receptor antagonist (IL-1ra) expression after brain trauma in the rat. Society for Neuroscience Abstracts 21, 200.2.
-
(1956)
Society for Neuroscience Abstracts
, vol.21
, pp. 2002
-
-
Toulmond, S.1
Rothwell, N.J.2
-
115
-
-
0026781413
-
Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons
-
TOULMOND, S., VIGE, X., FAGE, D. & BENAVIDES, J. (1992). Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons. Neuroscience Letters 144, 49-52.
-
(1992)
Neuroscience Letters
, vol.144
, pp. 49-52
-
-
Toulmond, S.1
Vige, X.2
Fage, D.3
Benavides, J.4
-
116
-
-
0029890689
-
The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase downregulation
-
TROY, C. C., STEFANIS, L., PROCHIANTZ, A., GREENE, L. A. & SHELANSKI, M. L. (1996). The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase downregulation. Proceedings of the National Academy of Sciences of the USA 93, 5635-5640.
-
(1996)
Proceedings of the National Academy of Sciences of the USA
, vol.93
, pp. 5635-5640
-
-
Troy, C.C.1
Stefanis, L.2
Prochiantz, A.3
Greene, L.A.4
Shelanski, M.L.5
-
117
-
-
0026503448
-
Coordinated antiinflammatory effects of interleukin 4: Interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist
-
VANNIER, E., MILLER, L. C. & DINARELLO, C. A. (1992). Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proceedings of the National Academy of Sciences of the USA 89, 4076-4080.
-
(1992)
Proceedings of the National Academy of Sciences of the USA
, vol.89
, pp. 4076-4080
-
-
Vannier, E.1
Miller, L.C.2
Dinarello, C.A.3
-
118
-
-
0031015932
-
Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats
-
WANG, X., BARONE, F., AIYAR, N. V. & FEUERSTEIN, G. Z. (1997). Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats. Stroke 28, 155-162.
-
(1997)
Stroke
, vol.28
, pp. 155-162
-
-
Wang, X.1
Barone, F.2
Aiyar, N.V.3
Feuerstein, G.Z.4
-
119
-
-
0029050267
-
Focal cerebral ischaemia induces CRH mRNA in rat cerebral cortex and amygdala
-
WONG, M. L., LODDICK, S. A., BONGIORNO, P. B., GOLD, P. W., LICINIO, J. & ROTHWELL, N. J. (1995). Focal cerebral ischaemia induces CRH mRNA in rat cerebral cortex and amygdala. NeuroReport 6, 1785-1788.
-
(1995)
NeuroReport
, vol.6
, pp. 1785-1788
-
-
Wong, M.L.1
Loddick, S.A.2
Bongiorno, P.B.3
Gold, P.W.4
Licinio, J.5
Rothwell, N.J.6
-
120
-
-
0028067834
-
An in situ hybridisation study of interleukin-1 beta induced by transient forebrain ischaemia in the rat brain
-
YABUUCHI, K., MINAMI, M., KATSUMATA, S., YAMASAKI, A. & SATOH, M. A. (1994). An in situ hybridisation study of interleukin-1 beta induced by transient forebrain ischaemia in the rat brain. Molecular Brain Research 26, 135-142.
-
(1994)
Molecular Brain Research
, vol.26
, pp. 135-142
-
-
Yabuuchi, K.1
Minami, M.2
Katsumata, S.3
Yamasaki, A.4
Satoh, M.A.5
-
121
-
-
0028958354
-
Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats
-
YAMASAKI, Y., MATSUURA, N., SHOZUHARA, H., ONODERA, H., ITOYAMA, Y. & KOGURE, K. (1995). Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26, 676-681.
-
(1995)
Stroke
, vol.26
, pp. 676-681
-
-
Yamasaki, Y.1
Matsuura, N.2
Shozuhara, H.3
Onodera, H.4
Itoyama, Y.5
Kogure, K.6
-
122
-
-
0028252906
-
Blocking of interleukin-1 activity is a beneficial approach to ischemia brain edema formation
-
YAMASAKI, Y., SHOZUHARA, H., ONODERA, H. & KOGURE, K. (1994). Blocking of interleukin-1 activity is a beneficial approach to ischemia brain edema formation. Acta Neurochirugica Supplement 60, 300-302.
-
(1994)
Acta Neurochirugica Supplement
, vol.60
, pp. 300-302
-
-
Yamasaki, Y.1
Shozuhara, H.2
Onodera, H.3
Kogure, K.4
-
123
-
-
0026636237
-
Possible involvement of interleukin-1 in ischemic brain edema formation
-
YAMASAKI, Y., SUZUKI, T., YAMAYA, H., MATSUURA, N., ONODERA, H. & KOGURE, K. (1992). Possible involvement of interleukin-1 in ischemic brain edema formation. Neuroscience Letters 142, 45-47.
-
(1992)
Neuroscience Letters
, vol.142
, pp. 45-47
-
-
Yamasaki, Y.1
Suzuki, T.2
Yamaya, H.3
Matsuura, N.4
Onodera, H.5
Kogure, K.6
-
124
-
-
0027525104
-
The C. Elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
YUAN, J., SHAHAM, S., LEDOUX, S., ELLIS, H. M. & HORVITZ, H. R. (1993). The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75, 641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
|