-
1
-
-
84890601822
-
Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension
-
S.L. Archer, Y.H. Fang, J.J. Ryan, and L. Piao Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension Pulm Circ 3 2013 144 152
-
(2013)
Pulm Circ
, vol.3
, pp. 144-152
-
-
Archer, S.L.1
Fang, Y.H.2
Ryan, J.J.3
Piao, L.4
-
2
-
-
77954083190
-
Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: A basis for excessive cell proliferation and a new therapeutic target
-
S.L. Archer, G. Marsboom, G.H. Kim, H.J. Zhang, P.T. Toth, and E.C. Svensson et al. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target Circulation 121 2010 2661 2671
-
(2010)
Circulation
, vol.121
, pp. 2661-2671
-
-
Archer, S.L.1
Marsboom, G.2
Kim, G.H.3
Zhang, H.J.4
Toth, P.T.5
Svensson, E.C.6
-
3
-
-
72449124776
-
Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure
-
H.J. Bogaard, R. Natarajan, S.C. Henderson, C.S. Long, D. Kraskauskas, and L. Smithson et al. Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure Circulation 120 2009 1951 1960
-
(2009)
Circulation
, vol.120
, pp. 1951-1960
-
-
Bogaard, H.J.1
Natarajan, R.2
Henderson, S.C.3
Long, C.S.4
Kraskauskas, D.5
Smithson, L.6
-
4
-
-
33745155785
-
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: Similarities to human pulmonary arterial hypertension
-
S. Bonnet, E.D. Michelakis, C.J. Porter, M.A. Andrade-Navarro, B. Thebaud, and S. Bonnet et al. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension Circulation 113 2006 2630 2641
-
(2006)
Circulation
, vol.113
, pp. 2630-2641
-
-
Bonnet, S.1
Michelakis, E.D.2
Porter, C.J.3
Andrade-Navarro, M.A.4
Thebaud, B.5
Bonnet, S.6
-
5
-
-
34547456414
-
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
-
S. Bonnet, G. Rochefort, G. Sutendra, S.L. Archer, A. Haromy, and L. Webster et al. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted Proc Natl Acad Sci USA 104 2007 11418 11423
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11418-11423
-
-
Bonnet, S.1
Rochefort, G.2
Sutendra, G.3
Archer, S.L.4
Haromy, A.5
Webster, L.6
-
6
-
-
84899137231
-
Molecular mechanisms of pulmonary arterial remodelling
-
P. Crosswhite, and Z. Sun Molecular mechanisms of pulmonary arterial remodelling Mol Med 20 2014 191 201
-
(2014)
Mol Med
, vol.20
, pp. 191-201
-
-
Crosswhite, P.1
Sun, Z.2
-
7
-
-
84873681470
-
Mitochondria in vascular health and disease
-
P. Dromparis, and E.D. Michelakis Mitochondria in vascular health and disease Annu Rev Physiol 75 2013 95 126
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 95-126
-
-
Dromparis, P.1
Michelakis, E.D.2
-
8
-
-
84872082742
-
Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension
-
P. Dromparis, R. Paulin, T.H. Stenson, A. Haromy, G. Sutendra, and E.D. Michelakis Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension Circulation 127 2013 115 125
-
(2013)
Circulation
, vol.127
, pp. 115-125
-
-
Dromparis, P.1
Paulin, R.2
Stenson, T.H.3
Haromy, A.4
Sutendra, G.5
Michelakis, E.D.6
-
9
-
-
84880569655
-
Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodelling and pulmonary hypertension
-
P. Dromparis, R. Paulin, G. Sutendra, A.C. Qi, S. Bonnet, and E.D. Michelakis Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodelling and pulmonary hypertension Circ Res 113 2013 126 136
-
(2013)
Circ Res
, vol.113
, pp. 126-136
-
-
Dromparis, P.1
Paulin, R.2
Sutendra, G.3
Qi, A.C.4
Bonnet, S.5
Michelakis, E.D.6
-
10
-
-
78149409004
-
The role of mitochondria in pulmonary vascular remodelling
-
P. Dromparis, G. Sutendra, and E.D. Michelakis The role of mitochondria in pulmonary vascular remodelling J Mol Med (Berl) 88 2010 1003 1010
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 1003-1010
-
-
Dromparis, P.1
Sutendra, G.2
Michelakis, E.D.3
-
11
-
-
84871238599
-
Dehydroepiandrosterone reverses chronic hypoxia/reoxygenation-induced right ventricular dysfunction in rats
-
E. Dumas de La Roque, N. Bellance, R. Rossignol, H. Begueret, M. Billaud, and P. dos Santos et al. Dehydroepiandrosterone reverses chronic hypoxia/reoxygenation-induced right ventricular dysfunction in rats Eur Respir J 40 2012 1420 1429
-
(2012)
Eur Respir J
, vol.40
, pp. 1420-1429
-
-
Roque De La E.Dumas1
Bellance, N.2
Rossignol, R.3
Begueret, H.4
Billaud, M.5
Dos Santos, P.6
-
12
-
-
84857361073
-
Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: Exploiting Randle's cycle
-
Y.H. Fang, L. Piao, Z. Hong, P.T. Toth, G. Marsboom, and P. Bache-Wiig et al. Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle J Mol Med (Berl) 90 2012 31 43
-
(2012)
J Mol Med (Berl)
, vol.90
, pp. 31-43
-
-
Fang, Y.H.1
Piao, L.2
Hong, Z.3
Toth, P.T.4
Marsboom, G.5
Bache-Wiig, P.6
-
13
-
-
77749291806
-
Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells
-
I. Fijalkowska, W. Xu, S.A. Comhair, A.J. Janocha, L.A. Mavrakis, and B. Krishnamachary et al. Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells Am J Pathol 176 2010 1130 1138
-
(2010)
Am J Pathol
, vol.176
, pp. 1130-1138
-
-
Fijalkowska, I.1
Xu, W.2
Comhair, S.A.3
Janocha, A.J.4
Mavrakis, L.A.5
Krishnamachary, B.6
-
14
-
-
84878343703
-
Reactive oxygen species as therapeutic targets in pulmonary hypertension
-
V. Freund-Michel, C. Guibert, M. Dubois, A. Courtois, R. Marthan, and J.P. Savineau et al. Reactive oxygen species as therapeutic targets in pulmonary hypertension Ther Adv Respir Dis 7 2013 175 200
-
(2013)
Ther Adv Respir Dis
, vol.7
, pp. 175-200
-
-
Freund-Michel, V.1
Guibert, C.2
Dubois, M.3
Courtois, A.4
Marthan, R.5
Savineau, J.P.6
-
15
-
-
84873647966
-
Metabolic gene remodelling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension
-
J. Gomez-Arroyo, S. Mizuno, K. Szczepanek, B. Van Tassell, R. Natarajan, and C.G. dos Remedios et al. Metabolic gene remodelling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension Circ Heart Fail 6 2013 136 144
-
(2013)
Circ Heart Fail
, vol.6
, pp. 136-144
-
-
Gomez-Arroyo, J.1
Mizuno, S.2
Szczepanek, K.3
Van Tassell, B.4
Natarajan, R.5
Dos Remedios, C.G.6
-
16
-
-
0024268337
-
Beneficial effects of trimetazidine on mitochondrial function and superoxide production in the cardiac muscle of monocrotaline-treated rats
-
C. Guarnieri, and C. Muscari Beneficial effects of trimetazidine on mitochondrial function and superoxide production in the cardiac muscle of monocrotaline-treated rats Biochem Pharmacol 37 1988 4685 4688
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 4685-4688
-
-
Guarnieri, C.1
Muscari, C.2
-
17
-
-
84861640093
-
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension
-
G. Marsboom, P.T. Toth, J.J. Ryan, Z. Hong, X. Wu, and Y.H. Fang et al. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension Circ Res 110 2012 1484 1497
-
(2012)
Circ Res
, vol.110
, pp. 1484-1497
-
-
Marsboom, G.1
Toth, P.T.2
Ryan, J.J.3
Hong, Z.4
Wu, X.5
Fang, Y.H.6
-
18
-
-
6344257102
-
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
-
M.S. McMurtry, S. Bonnet, X. Wu, J.R. Dyck, A. Haromy, and K. Hashimoto et al. Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis Circ Res 95 2004 830 840
-
(2004)
Circ Res
, vol.95
, pp. 830-840
-
-
McMurtry, M.S.1
Bonnet, S.2
Wu, X.3
Dyck, J.R.4
Haromy, A.5
Hashimoto, K.6
-
19
-
-
84879816142
-
Pulmonary arterial hypertension
-
D. Montani, S. Gunther, P. Dorfmuller, F. Perros, B. Girerd, and G. Garcia et al. Pulmonary arterial hypertension Orphanet J Rare Dis 8 2013 97
-
(2013)
Orphanet J Rare Dis
, vol.8
, pp. 97
-
-
Montani, D.1
Gunther, S.2
Dorfmuller, P.3
Perros, F.4
Girerd, B.5
Garcia, G.6
-
20
-
-
67650069940
-
Endothelin receptor blockade combined with phosphodiesterase-5 inhibition increases right ventricular mitochondrial capacity in pulmonary arterial hypertension
-
K.T. Mouchaers, I. Schalij, A.M. Versteilen, A.M. Hadi, G.P. van Nieuw Amerongen, and V.W. van Hinsbergh et al. Endothelin receptor blockade combined with phosphodiesterase-5 inhibition increases right ventricular mitochondrial capacity in pulmonary arterial hypertension Am J Physiol Heart Circ Physiol 297 2009 H200 H207
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Mouchaers, K.T.1
Schalij, I.2
Versteilen, A.M.3
Hadi, A.M.4
Van Nieuw Amerongen, G.P.5
Van Hinsbergh, V.W.6
-
21
-
-
78650605092
-
Chronic hypoxia-induced alterations in mitochondrial energy metabolism are not reversible in rat heart ventricles
-
K. Nouette-Gaulain, M. Biais, J.P. Savineau, R. Marthan, J.P. Mazat, and T. Letellier et al. Chronic hypoxia-induced alterations in mitochondrial energy metabolism are not reversible in rat heart ventricles Can J Physiol Pharmacol 89 2011 58 66
-
(2011)
Can J Physiol Pharmacol
, vol.89
, pp. 58-66
-
-
Nouette-Gaulain, K.1
Biais, M.2
Savineau, J.P.3
Marthan, R.4
Mazat, J.P.5
Letellier, T.6
-
22
-
-
14844356019
-
Time course of differential mitochondrial energy metabolism adaptation to chronic hypoxia in right and left ventricles
-
K. Nouette-Gaulain, M. Malgat, C. Rocher, J.P. Savineau, R. Marthan, and J.P. Mazat et al. Time course of differential mitochondrial energy metabolism adaptation to chronic hypoxia in right and left ventricles Cardiovasc Res 66 2005 132 140
-
(2005)
Cardiovasc Res
, vol.66
, pp. 132-140
-
-
Nouette-Gaulain, K.1
Malgat, M.2
Rocher, C.3
Savineau, J.P.4
Marthan, R.5
Mazat, J.P.6
-
23
-
-
84883478565
-
Mitochondrial hyperpolarization in pulmonary vascular remodelling. Mitochondrial uncoupling protein deficiency as disease model
-
O. Pak, N. Sommer, T. Hoeres, A. Bakr, S. Waisbrod, and A. Sydykov et al. Mitochondrial hyperpolarization in pulmonary vascular remodelling. Mitochondrial uncoupling protein deficiency as disease model Am J Respir Cell Mol Biol 49 2013 358 367
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 358-367
-
-
Pak, O.1
Sommer, N.2
Hoeres, T.3
Bakr, A.4
Waisbrod, S.5
Sydykov, A.6
-
24
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
I. Papandreou, R.A. Cairns, L. Fontana, A.L. Lim, and N.C. Denko HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption Cell Metab 3 2006 187 197
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
25
-
-
84902968590
-
The metabolic theory of pulmonary arterial hypertension
-
R. Paulin, and E.D. Michelakis The metabolic theory of pulmonary arterial hypertension Circ Res 115 2014 148 164
-
(2014)
Circ Res
, vol.115
, pp. 148-164
-
-
Paulin, R.1
Michelakis, E.D.2
-
26
-
-
84885298464
-
Cardiac glutaminolysis: A maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension
-
L. Piao, Y.H. Fang, K. Parikh, J.J. Ryan, P.T. Toth, and S.L. Archer Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension J Mol Med (Berl) 91 2013 1185 1197
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 1185-1197
-
-
Piao, L.1
Fang, Y.H.2
Parikh, K.3
Ryan, J.J.4
Toth, P.T.5
Archer, S.L.6
-
27
-
-
78149415338
-
Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure
-
L. Piao, G. Marsboom, and S.L. Archer Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure J Mol Med (Berl) 88 2010 1011 1020
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 1011-1020
-
-
Piao, L.1
Marsboom, G.2
Archer, S.L.3
-
28
-
-
84891671691
-
FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: Therapeutic benefits of dichloroacetate
-
L. Piao, V.K. Sidhu, Y.H. Fang, J.J. Ryan, K.S. Parikh, and Z. Hong et al. FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate J Mol Med (Berl) 91 2013 333 346
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 333-346
-
-
Piao, L.1
Sidhu, V.K.2
Fang, Y.H.3
Ryan, J.J.4
Parikh, K.S.5
Hong, Z.6
-
29
-
-
34547828784
-
Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species
-
E.M. Redout, M.J. Wagner, M.J. Zuidwijk, C. Boer, R.J. Musters, and C. van Hardeveld et al. Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species Cardiovasc Res 75 2007 770 781
-
(2007)
Cardiovasc Res
, vol.75
, pp. 770-781
-
-
Redout, E.M.1
Wagner, M.J.2
Zuidwijk, M.J.3
Boer, C.4
Musters, R.J.5
Van Hardeveld, C.6
-
30
-
-
79960031695
-
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: Clinical prevalence, outcomes, and mechanistic insights
-
C.J. Rhodes, L.S. Howard, M. Busbridge, D. Ashby, E. Kondili, and J.S. Gibbs et al. Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights J Am Coll Cardiol 58 2011 300 309
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 300-309
-
-
Rhodes, C.J.1
Howard, L.S.2
Busbridge, M.3
Ashby, D.4
Kondili, E.5
Gibbs, J.S.6
-
31
-
-
79957975690
-
Iron deficiency in pulmonary arterial hypertension: A potential therapeutic target
-
C.J. Rhodes, J. Wharton, L. Howard, J.S. Gibbs, A. Vonk-Noordegraaf, and M.R. Wilkins Iron deficiency in pulmonary arterial hypertension: a potential therapeutic target Eur Respir J 38 2011 1453 1460
-
(2011)
Eur Respir J
, vol.38
, pp. 1453-1460
-
-
Rhodes, C.J.1
Wharton, J.2
Howard, L.3
Gibbs, J.S.4
Vonk-Noordegraaf, A.5
Wilkins, M.R.6
-
32
-
-
47249137061
-
Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: Role of mitochondrial dysfunction
-
N. Sud, S.M. Wells, S. Sharma, D.A. Wiseman, J. Wilham, and S.M. Black Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction Am J Physiol Cell Physiol 294 2008 C1407 C1418
-
(2008)
Am J Physiol Cell Physiol
, vol.294
-
-
Sud, N.1
Wells, S.M.2
Sharma, S.3
Wiseman, D.A.4
Wilham, J.5
Black, S.M.6
-
33
-
-
84875939562
-
Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow
-
X. Sun, S. Sharma, S. Fratz, S. Kumar, R. Rafikov, and S. Aggarwal et al. Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow Antioxid Redox Signal 18 2013 1739 1752
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1739-1752
-
-
Sun, X.1
Sharma, S.2
Fratz, S.3
Kumar, S.4
Rafikov, R.5
Aggarwal, S.6
-
34
-
-
77955635790
-
Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodelling of pulmonary hypertension
-
G. Sutendra, S. Bonnet, G. Rochefort, A. Haromy, K.D. Folmes, and G.D. Lopaschuk et al. Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodelling of pulmonary hypertension Sci Transl Med 2 2010 44ra58
-
(2010)
Sci Transl Med
, vol.2
-
-
Sutendra, G.1
Bonnet, S.2
Rochefort, G.3
Haromy, A.4
Folmes, K.D.5
Lopaschuk, G.D.6
-
35
-
-
80052459025
-
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFalpha contributes to the pathogenesis of pulmonary arterial hypertension
-
G. Sutendra, P. Dromparis, S. Bonnet, A. Haromy, M.S. McMurtry, and R.C. Bleackley et al. Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFalpha contributes to the pathogenesis of pulmonary arterial hypertension J Mol Med (Berl) 89 2011 771 783
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 771-783
-
-
Sutendra, G.1
Dromparis, P.2
Bonnet, S.3
Haromy, A.4
McMurtry, M.S.5
Bleackley, R.C.6
-
36
-
-
84888636768
-
A metabolic remodelling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension
-
G. Sutendra, P. Dromparis, R. Paulin, S. Zervopoulos, A. Haromy, and J. Nagendran et al. A metabolic remodelling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension J Mol Med (Berl) 91 2013 1315 1327
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 1315-1327
-
-
Sutendra, G.1
Dromparis, P.2
Paulin, R.3
Zervopoulos, S.4
Haromy, A.5
Nagendran, J.6
-
37
-
-
79959464127
-
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension
-
G. Sutendra, P. Dromparis, P. Wright, S. Bonnet, A. Haromy, and Z. Hao et al. The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension Sci Transl Med 3 2011 88ra55
-
(2011)
Sci Transl Med
, vol.3
-
-
Sutendra, G.1
Dromparis, P.2
Wright, P.3
Bonnet, S.4
Haromy, A.5
Hao, Z.6
-
38
-
-
84897568503
-
The metabolic basis of pulmonary arterial hypertension
-
G. Sutendra, and E.D. Michelakis The metabolic basis of pulmonary arterial hypertension Cell Metab 19 2014 558 573
-
(2014)
Cell Metab
, vol.19
, pp. 558-573
-
-
Sutendra, G.1
Michelakis, E.D.2
-
39
-
-
84904321037
-
Mitochondria, endothelial cell function, and vascular diseases
-
X. Tang, Y.X. Luo, H.Z. Chen, and D.P. Liu Mitochondria, endothelial cell function, and vascular diseases Front Physiol 5 2014 175
-
(2014)
Front Physiol
, vol.5
, pp. 175
-
-
Tang, X.1
Luo, Y.X.2
Chen, H.Z.3
Liu, D.P.4
-
40
-
-
66049112085
-
Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: New findings for an old problem
-
J.P. Ward, and I.F. McMurtry Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem Curr Opin Pharmacol 9 2009 287 296
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 287-296
-
-
Ward, J.P.1
McMurtry, I.F.2
-
41
-
-
84861980093
-
Endothelial cell energy metabolism, proliferation, and apoptosis in pulmonary hypertension
-
W. Xu, and S.C. Erzurum Endothelial cell energy metabolism, proliferation, and apoptosis in pulmonary hypertension Compr Physiol 1 2011 357 372
-
(2011)
Compr Physiol
, vol.1
, pp. 357-372
-
-
Xu, W.1
Erzurum, S.C.2
-
42
-
-
33846614655
-
Alterations of cellular bioenergetics in pulmonary artery endothelial cells
-
W. Xu, T. Koeck, A.R. Lara, D. Neumann, F.P. DiFilippo, and M. Koo et al. Alterations of cellular bioenergetics in pulmonary artery endothelial cells Proc Natl Acad Sci USA 104 2007 1342 1347
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1342-1347
-
-
Xu, W.1
Koeck, T.2
Lara, A.R.3
Neumann, D.4
Difilippo, F.P.5
Koo, M.6
-
43
-
-
84872037440
-
Activation of the unfolded protein response is associated with pulmonary hypertension
-
M.E. Yeager, M.B. Reddy, C.M. Nguyen, K.L. Colvin, D.D. Ivy, and K.R. Stenmark Activation of the unfolded protein response is associated with pulmonary hypertension Pulm Circ 2 2012 229 240
-
(2012)
Pulm Circ
, vol.2
, pp. 229-240
-
-
Yeager, M.E.1
Reddy, M.B.2
Nguyen, C.M.3
Colvin, K.L.4
Ivy, D.D.5
Stenmark, K.R.6
-
44
-
-
0032491187
-
Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension
-
J.X. Yuan, A.M. Aldinger, M. Juhaszova, J. Wang, J.V. Conte Jr., and S.P. Gaine et al. Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension Circulation 98 1998 1400 1406
-
(1998)
Circulation
, vol.98
, pp. 1400-1406
-
-
Yuan, J.X.1
Aldinger, A.M.2
Juhaszova, M.3
Wang, J.4
Conte, Jr.J.V.5
Gaine, S.P.6
-
45
-
-
0035229427
-
The mitochondrion in apoptosis: How Pandora's box opens
-
N. Zamzami, and G. Kroemer The mitochondrion in apoptosis: how Pandora's box opens Nat Rev Mol Cell Biol 2 2001 67 71
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 67-71
-
-
Zamzami, N.1
Kroemer, G.2
-
46
-
-
84884354660
-
Heterogeneity in lung (18)FDG uptake in pulmonary arterial hypertension: Potential of dynamic (18)FDG positron emission tomography with kinetic analysis as a bridging biomarker for pulmonary vascular remodelling targeted treatments
-
L. Zhao, A. Ashek, L. Wang, W. Fang, S. Dabral, and O. Dubois et al. Heterogeneity in lung (18)FDG uptake in pulmonary arterial hypertension: potential of dynamic (18)FDG positron emission tomography with kinetic analysis as a bridging biomarker for pulmonary vascular remodelling targeted treatments Circulation 128 2013 1214 1224
-
(2013)
Circulation
, vol.128
, pp. 1214-1224
-
-
Zhao, L.1
Ashek, A.2
Wang, L.3
Fang, W.4
Dabral, S.5
Dubois, O.6
-
47
-
-
84864290214
-
Histone deacetylation inhibition in pulmonary hypertension: Therapeutic potential of valproic acid and suberoylanilide hydroxamic acid
-
L. Zhao, C.N. Chen, N. Hajji, E. Oliver, E. Cotroneo, and J. Wharton et al. Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid Circulation 126 2012 455 467
-
(2012)
Circulation
, vol.126
, pp. 455-467
-
-
Zhao, L.1
Chen, C.N.2
Hajji, N.3
Oliver, E.4
Cotroneo, E.5
Wharton, J.6
|