Mitochondrial hyperpolarization in pulmonary vascular remodeling: Mitochondrial uncoupling protein deficiency as disease model

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 3, 2013, Pages 348-357

  Pak, Oleg ^a   Sommer, Natascha ^a   Hoeres, Timm ^a   Bakr, Adel ^b   Waisbrod, Sharon ^a   Sydykov, Akylbek ^a   Haag, Daniela ^a   Esfandiary, Azadeh ^a   Kojonazarov, Baktybek ^a   Veit, Florian ^a   Fuchs, Beate ^a   Weisel, Friederike Christine ^a   Hecker, Matthias ^a   Schermuly, Ralph Theo ^a   Grimminger, Friedrich ^a   Ghofrani, Hossein Ardeschir ^a   Seeger, Werner ^a   Weissmann, Norbert ^a  

^a JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^b Al Azhar University   (Egypt)

Author keywords

Mitochondria; Mitochondrial membrane potential; Pulmonary hypertension; Reactive oxygen species; UCP2

Indexed keywords

CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; MONOCROTALINE; SMALL INTERFERING RNA; 5,5',6,6' TETRACHLORO 1,1',3,3' TETRAETHYLBENZIMIDAZOLOCARBOCYANINE; 5,5',6,6'-TETRACHLORO-1,1',3,3'-TETRAETHYLBENZIMIDAZOLOCARBOCYANINE; BENZIMIDAZOLE DERIVATIVE; CARBOCYANINE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CARBONYLCYANIDE 4-TRIFLUOROMETHOXYPHENYLHYDRAZONE; DRUG DERIVATIVE; FLUORESCENT DYE; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; REACTIVE OXYGEN METABOLITE; SCAVENGER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ECHOCARDIOGRAPHY; ELECTRON SPIN RESONANCE; FEMALE; HEMODYNAMICS; HUMAN; HYPERPOLARIZATION; HYPOXIA; LUNG BLOOD VESSEL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MORPHOMETRICS; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PROTEIN DEFICIENCY; PULMONARY HYPERTENSION; SMOOTH MUSCLE FIBER; ANIMAL; ANOXIA; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PRIMARY CELL CULTURE; PULMONARY ARTERY; RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANOXIA; BENZIMIDAZOLES; CARBOCYANINES; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; DISEASE MODELS, ANIMAL; FLUORESCENT DYES; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; HUMANS; HYPERTENSION, PULMONARY; ION CHANNELS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MONOCROTALINE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PRIMARY CELL CULTURE; PULMONARY ARTERY; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 84883478565     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0361OC     Document Type: Article

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