Model-based cell number quantification using online single-oxygen sensor data for tissue engineering perfusion bioreactors

Biotechnology and Bioengineering

Volumn 111, Issue 10, 2014, Pages 1982-1992

  Lambrechts, T ^a   Papantoniou, I ^a,b   Sonnaert, M ^a   Schrooten, J ^a,b   Aerts, J M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b SKELETAL BIOLOGY AND ENGINEERING RESEARCH CENTER   (Belgium)

Author keywords

Bioprocess control; Data based mechanistic modeling; Online monitoring; Oxygen sensor; Stem cell bioreactor; Tissue engineering

Indexed keywords

BIOCONVERSION; BIOREACTORS; CELLULAR MANUFACTURING; CYTOLOGY; METABOLISM; OXYGEN SENSORS; STEM CELLS; TISSUE ENGINEERING;

BIOPROCESS CONTROL; BIOPROCESS MONITORING; CELL BIOREACTORS; MECHANISTIC MODELING; MONITORING TECHNIQUES; NON-DESTRUCTIVE MEASUREMENT; ONLINE MONITORING; PERFUSION CONDITIONS;

SCAFFOLDS (BIOLOGY);

OXYGEN;

ARTICLE; AUTOMATION; BIOPROCESS; BIOREACTOR; CELL COUNT; CONTROLLED STUDY; CORRELATIONAL STUDY; COST EFFECTIVENESS ANALYSIS; DYNAMICS; HUMAN; HUMAN CELL; NON INVASIVE MEASUREMENT; ONLINE MONITORING; OXYGEN CONCENTRATION; OXYGEN SENSOR; SENSOR; TISSUE ENGINEERING; TISSUE PERFUSION; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DEVICES; EQUIPMENT DESIGN; GENETIC PROCEDURES; METABOLISM; PERFUSION; STEM CELL; TISSUE SCAFFOLD;

BIOREACTORS; BIOSENSING TECHNIQUES; CELL COUNT; CELL CULTURE TECHNIQUES; CELLS, CULTURED; EQUIPMENT DESIGN; HUMANS; MODELS, BIOLOGICAL; OXYGEN; PERFUSION; STEM CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84906788020     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25274     Document Type: Article

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