-
1
-
-
35548954677
-
Engineering microbial cell factories for biosynthesis of isoprenoid molecules: Beyond lycopene
-
DOI 10.1016/j.tibtech.2007.07.006, PII S0167779907001862
-
Klein-Marcuschamer D, Ajikumar PK, Stephanopoulos G (2007) Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene. Trends Biotechnol 25, 417-424. (Pubitemid 350147115)
-
(2007)
Trends in Biotechnology
, vol.25
, Issue.9
, pp. 417-424
-
-
Klein-Marcuschamer, D.1
Ajikumar, P.K.2
Stephanopoulos, G.3
-
2
-
-
77249149861
-
Biofuel production in escherichia coli: The role of metabolic engineering and synthetic biology
-
Clomburg JM, Gonzalez R (2010) Biofuel production in Escherichia coli: the role of metabolic engineering and synthetic biology. Appl Microbiol Biotechnol 86, 419-434.
-
(2010)
Appl Microbiol Biotechnol
, vol.86
, pp. 419-434
-
-
Clomburg, J.M.1
Gonzalez, R.2
-
3
-
-
33847030736
-
Industrial biotechnology for the production of bio-based chemicals - a cradle-to-grave perspective
-
DOI 10.1016/j.tibtech.2007.01.001, PII S0167779907000170
-
Hatti-Kaul R, Tornvall U, Gustafsson L, Borjesson P (2007) Industrial biotechnology for the production of bio-based chemicals - a cradle-to-grave perspective. Trends Biotechnol 25, 119-124. (Pubitemid 46273751)
-
(2007)
Trends in Biotechnology
, vol.25
, Issue.3
, pp. 119-124
-
-
Hatti-Kaul, R.1
Tornvall, U.2
Gustafsson, L.3
Borjesson, P.4
-
4
-
-
79955894117
-
Genetically engineered bacteria: An emerging tool for environmental remediation and future research perspectives
-
Singh JS, Abhilash PC, Singh HB, Singh RP, Singh DP (2011) Genetically engineered bacteria: An emerging tool for environmental remediation and future research perspectives. Gene 480, 1-9.
-
(2011)
Gene
, vol.480
, pp. 1-9
-
-
Singh, J.S.1
Abhilash, P.C.2
Singh, H.B.3
Singh, R.P.4
Singh, D.P.5
-
5
-
-
57049098094
-
Metabolic engineering of microorganisms for biofuels production: From bugs to synthetic biology to fuels
-
Lee SK, Chou H, Ham TS, Lee TS, Keasling JD (2008) Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels. Curr Opin Biotechnol 19, 556-563.
-
(2008)
Curr Opin Biotechnol
, vol.19
, pp. 556-563
-
-
Lee, S.K.1
Chou, H.2
Ham, T.S.3
Lee, T.S.4
Keasling, J.D.5
-
6
-
-
57049150206
-
Selection and optimization of microbial hosts for biofuel production
-
Fischer CR, Klein-Marcuschamer D, Stephanopoulos G (2008) Selection and optimization of microbial hosts for biofuel production. MetabEng 10, 295-304.
-
(2008)
MetabEng
, vol.10
, pp. 295-304
-
-
Fischer, C.R.1
Klein-Marcuschamer, D.2
Stephanopoulos, G.3
-
7
-
-
66249088017
-
The second wave of synthetic biology: From modules to systems
-
Purnick PEM, Weiss R (2009) The second wave of synthetic biology: from modules to systems. Nat Rev Mol Cell Biol 10, 410-422.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 410-422
-
-
Purnick, P.E.M.1
Weiss, R.2
-
8
-
-
83955163721
-
Designing biological systems: Systems engineering meets synthetic biology
-
Rollie S, Mangold M, Sundmacher K (2012) Designing biological systems: Systems Engineering meets Synthetic Biology. Chem Eng Sci 69, 1-29.
-
(2012)
Chem Eng Sci
, vol.69
, pp. 1-29
-
-
Rollie, S.1
Mangold, M.2
Sundmacher, K.3
-
9
-
-
47249096975
-
Application of systems biology for bioprocess development
-
Park JH, Lee SY, Kim TY, Kim HU (2008) Application of systems biology for bioprocess development. Trends Biotechnol 26, 404-412.
-
(2008)
Trends Biotechnol
, vol.26
, pp. 404-412
-
-
Park, J.H.1
Lee, S.Y.2
Kim, T.Y.3
Kim, H.U.4
-
10
-
-
78649716727
-
Manufacturing molecules through metabolic engineering
-
Keasling JD (2010) Manufacturing molecules through metabolic engineering. Science 330, 1355-1358.
-
(2010)
Science
, vol.330
, pp. 1355-1358
-
-
Keasling, J.D.1
-
12
-
-
75449094838
-
Sequences and consequences
-
Brenner S (2010) Sequences and consequences. Philos T Roy Soc B 365, 207-212.
-
(2010)
Philos T Roy Soc B
, vol.365
, pp. 207-212
-
-
Brenner, S.1
-
14
-
-
84902160656
-
-
Biotechnology Industry Organisation (2010
-
Biotechnology Industry Organisation (2010) http://bio.org.
-
-
-
-
15
-
-
78651440490
-
Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal cells in bioreactor
-
Xie L, Wang DIC (1994) Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal cells in bioreactor. Growth Factors 1, 17-29.
-
(1994)
Growth Factors
, vol.1
, pp. 17-29
-
-
Xie, L.1
Wang, D.I.C.2
-
16
-
-
0034609598
-
Phosphate feeding improves high-cell-concentration ns0 myeloma culture performance for monoclonal antibody production
-
De Zengotita MV, Miller WM, Aunins JG (2000) Phosphate feeding improves high-cell-concentration NS0 myeloma culture performance for monoclonal antibody production. Biotechnol Bioeng 69, 566-676.
-
(2000)
Biotechnol Bioeng
, vol.69
, pp. 566-676
-
-
De Zengotita, M.V.1
Miller, W.M.2
Aunins, J.G.3
-
17
-
-
0026542004
-
Optimization of fed-batch culture of hybridoma cells using dynamic programming: Single and multi feed cases
-
de Tremblay M, Perrier M, Chavarie C, Achambault J (1992) Optimization of fed-batch culture of hybridoma cells using dynamic programming: single and multi feed cases. Bioprocess Eng 7, 229-234.
-
(1992)
Bioprocess Eng
, vol.7
, pp. 229-234
-
-
De Tremblay, M.1
Perrier, M.2
Chavarie, C.3
Achambault, J.4
-
18
-
-
0034688179
-
Dynamic optimisation of hybridoma growth in a fed-batch bioreactor
-
Dhir S, Morrow KJ, Rhinehart RR, Wiesner T (1999) Dynamic optimisation of hybridoma growth in a fed-batch bioreactor. Biotechnol Bioeng 67, 197-205.
-
(1999)
Biotechnol Bioeng
, vol.67
, pp. 197-205
-
-
Dhir, S.1
Morrow, K.J.2
Rhinehart, R.R.3
Wiesner, T.4
-
19
-
-
0036752465
-
Adaptive, model-based control by the Open-Loop-Feedback-Optimal (OLFO) controller for the effective fed-batch cultivation of hybridoma cells
-
DOI 10.1021/bp020035y
-
Frahm B, Lane P, Atzert H, Munack A, Hoffmann M, et al. (2002) Adaptive, model-based control by the open-loop-feedback-optimal (OLFO) controller for the effective fed-batch cultivation of hybridoma cells. Biotechnol Prog 18, 1095-1103. (Pubitemid 35211933)
-
(2002)
Biotechnology Progress
, vol.18
, Issue.5
, pp. 1095-1103
-
-
Frahm, B.1
Lane, P.2
Atzert, H.3
Munack, A.4
Hoffmann, M.5
Hass, V.C.6
Portner, R.7
-
20
-
-
0030595039
-
Modelling hybridoma cell growth and metabolism a comparison of selected models and data
-
DOI 10.1016/0168-1656(96)01535-0
-
Portner R, Schafer T (1996) Modelling hybridoma cell growth and metabolism - a comparison of selected models and data. J Biotechnol 49, 119-135. (Pubitemid 26316248)
-
(1996)
Journal of Biotechnology
, vol.49
, Issue.1-3
, pp. 119-135
-
-
Portner, R.1
Schafer, T.2
-
21
-
-
0035281870
-
Metabolic modeling of microbial strains in silico
-
DOI 10.1016/S0968-0004(00)01754-0, PII S0968000400017540
-
Covert MW, Schilling CH, Famili I, Edwards JS, Goryanin II, et al. (2001) Metabolic modeling of microbial strains in silico. Trends Biochem Sci 26, 179-186. (Pubitemid 32197578)
-
(2001)
Trends in Biochemical Sciences
, vol.26
, Issue.3
, pp. 179-186
-
-
Covert, M.W.1
Schilling, C.H.2
Famili, I.3
Edwards, J.S.4
Goryanin, I.I.5
Selkov, E.6
Palsson, B.O.7
-
22
-
-
0000870544
-
Die Kinetik der Invertinwirkung
-
Menten L, Michaelis MI (1913) Die Kinetik der Invertinwirkung. Biochem Z 49, 333-369.
-
(1913)
Biochem Z
, vol.49
, pp. 333-369
-
-
Menten, L.1
Michaelis, M.I.2
-
23
-
-
0001639179
-
The growth of bacterial cultures
-
Monod J (1949) The growth of bacterial cultures.Annu Rev Microbiol 3, 371-394.
-
(1949)
Annu Rev Microbiol
, vol.3
, pp. 371-394
-
-
Monod, J.1
-
24
-
-
0031933027
-
Mathematical modeling and analysis in biochemical engineering: Past accomplishments and future opportunities
-
DOI 10.1021/bp9701269
-
Bailey JE (1998) Mathematical modeling and analysis in biochemical engineering: Past accomplishments and future opportunities. Biotechnol Prog 14, 8-20. (Pubitemid 28118259)
-
(1998)
Biotechnology Progress
, vol.14
, Issue.1
, pp. 8-20
-
-
Bailey, J.E.1
-
25
-
-
0001886686
-
A cybernetic perspective of microbial growth
-
In: Blanch HW, Papoutsakis ET, Stephanopoulos GN, editors. Washington, DC: American Chemical Society
-
Ramkrishna D (1983) A cybernetic perspective of microbial growth. In: Blanch HW, Papoutsakis ET, Stephanopoulos GN, editors. Foundations of biochemical engineering: kinetics and thermodynamics in biological systems. Washington, DC: American Chemical Society, pp. 161-178.
-
(1983)
Foundations of Biochemical Engineering: Kinetics and Thermodynamics in Biological Systems.
, pp. 161-178
-
-
Ramkrishna, D.1
-
27
-
-
0021341080
-
A mathematical model for λdv plasmid replication: Analysis of wild-type plasmid
-
Lee SB, Bailey JE (1984a) A mathematical model for Xdv plasmid replication: analysis of wild-type plasmid. Plasmid 11, 151-165. (Pubitemid 14149615)
-
(1984)
Plasmid
, vol.11
, Issue.2
, pp. 151-165
-
-
Lee, S.B.1
Bailey, J.E.2
-
28
-
-
0021348306
-
A mathematical model for λdv plasmid replication: Analysis of copy number mutants
-
Lee SB, Bailey JE (1984b) A mathematical model for Xdv plasmid replication: analysis of copy number mutants. Plasmid 11, 166-177. (Pubitemid 14149616)
-
(1984)
Plasmid
, vol.11
, Issue.2
, pp. 166-177
-
-
Lee, S.B.1
Bailey, J.E.2
-
29
-
-
0021531929
-
Cybernetic modeling of microbial growth on multiple substrates
-
DOI 10.1002/bit.260261103
-
Kompala DS, Ramkrishna D, Tsao GT (1984) Cybernetic modeling of microbial growth on multiple substrates. Biotechnol Bioeng 26, 1272-1281. (Pubitemid 15224150)
-
(1984)
Biotechnology and Bioengineering
, vol.26
, Issue.11
, pp. 1272-1281
-
-
Kompala, D.S.1
Ramkrishna, D.2
Tsao, G.T.3
-
30
-
-
0014649230
-
Biochemical systems analysis: I. Some mathematical properties of the rate law for the component enzymatic reactions
-
Savageau MA (1969a) Biochemical systems analysis: I. Some mathematical properties of the rate law for the component enzymatic reactions. J Theor Biol 25, 365-369.
-
(1969)
J Theor Biol
, vol.25
, pp. 365-369
-
-
Savageau, M.A.1
-
31
-
-
0014658880
-
Biochemical systems analysis: Ii. The steady-state solutions for an n-pool system using a power-law approximation
-
Savageau MA (1969b) Biochemical systems analysis: II. The steady-state solutions for an n-pool system using a power-law approximation. J Theor Biol 25, 370-379.
-
(1969)
J Theor Biol
, vol.25
, pp. 370-379
-
-
Savageau, M.A.1
-
32
-
-
0014733809
-
Biochemical systems analysis: Iii.dynamic solutions using a power-law approximation
-
Savageau MA (1970) Biochemical systems analysis: III.Dynamic solutions using a power-law approximation. J Theor Biol 26, 215-226.
-
(1970)
J Theor Biol
, vol.26
, pp. 215-226
-
-
Savageau, M.A.1
-
33
-
-
0015231849
-
Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems
-
Savageau MA (1971) Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems. Nature 229, 542-544.
-
(1971)
Nature
, vol.229
, pp. 542-544
-
-
Savageau, M.A.1
-
35
-
-
0015989446
-
A linear steady-state treatment of enzymatic chains general properties, control and effector strength
-
Heinrich R, Rapoport TA (1974) A linear steady-state treatment of enzymatic chains general properties, control and effector strength. EurJ Biochem 42, 89-95.
-
(1974)
EurJ Biochem
, vol.42
, pp. 89-95
-
-
Heinrich, R.1
Rapoport, T.A.2
-
36
-
-
0021383728
-
Equations and calculations for fermentations of butyric bacteria
-
DOI 10.1002/bit.260260210
-
Papoutsakis ET (1984) Equations and calculations for fermentations of butyric acid bacteria. Biotechnol Bioeng 26, 174-187. (Pubitemid 14155510)
-
(1984)
Biotechnology and Bioengineering
, vol.26
, Issue.2
, pp. 174-187
-
-
Papoutsakis, E.T.1
-
37
-
-
0022493181
-
Fat synthesis in adipose tissue. An examination of stoichiometric constraints
-
Fell DA, Small JR (1986) Fat synthesis in adipose tissue.An examination of stoichiometric constraints. Biochem J 238, 781-786. (Pubitemid 16004713)
-
(1986)
Biochemical Journal
, vol.238
, Issue.3
, pp. 781-786
-
-
Fell, D.A.1
Small, J.R.2
-
39
-
-
0025895183
-
Toward a science of metabolic engineering
-
Bailey JE (1991) Toward a science of metabolic engineering. Science 252, 1668-1675. (Pubitemid 21917084)
-
(1991)
Science
, vol.252
, Issue.5013
, pp. 1668-1675
-
-
Bailey, J.E.1
-
40
-
-
0032600888
-
Metabolic fluxes and metabolic engineering
-
DOI 10.1006/mben.1998.0101, PII S109671769890101X
-
Stephanopoulos G (1999) Metabolic fluxes and metabolic engineering. Metab Eng 1, 1 - 11. (Pubitemid 129499367)
-
(1999)
Metabolic Engineering
, vol.1
, Issue.1
, pp. 1-11
-
-
Stephanopoulos, G.1
-
42
-
-
0025866296
-
Network rigidity and metabolic engineering in metabolite overproduction
-
Stephanopoulos G, Vallino JJ (1991) Network rigidity and metabolic engineering in metabolite overproduction. Science 252, 1675-1681. (Pubitemid 21917085)
-
(1991)
Science
, vol.252
, Issue.5013
, pp. 1675-1681
-
-
Stephanopoulos, G.1
Vallino, J.J.2
-
43
-
-
34548200846
-
DAISY: A new software tool to test global identifiability of biological and physiological systems
-
DOI 10.1016/j.cmpb.2007.07.002, PII S0169260707001605
-
Bellu G, Saccomani MP, Audoly S, D'Angio L (2007). DAISY: a new software tool to test global identifiability of biological and physiological systems. Comput Meth Prog Biomed 88, 52-61. (Pubitemid 47331951)
-
(2007)
Computer Methods and Programs in Biomedicine
, vol.88
, Issue.1
, pp. 52-61
-
-
Bellu, G.1
Saccomani, M.P.2
Audoly, S.3
D'Angio, L.4
-
44
-
-
0031554884
-
Fed-batch culture of recombinant NSO myeloma cells with high monoclonal antibody production
-
DOI 10.1002/(SICI)1097-0290(19970905)55:5<783: :AID-BIT8>3.0.CO;2-7
-
Zhou W, Chen CC, Buckland B, Aunins J (1997a) Fed-batch culture of recombinant NSO myeloma cells with high monoclonal antibody production. Biotechnol Bioeng 55, 783-792. (Pubitemid 27328224)
-
(1997)
Biotechnology and Bioengineering
, vol.55
, Issue.5
, pp. 783-792
-
-
Zhou, W.1
Chen, C.-C.2
Buckland, B.3
Aunins, J.4
-
45
-
-
0030916886
-
Alteration of mammalian cell metabolism by dynamic nutrient feeding
-
DOI 10.1023/A:1007945826228
-
Zhou W, Rehm J, Europa A, Hu WS (1997b) Alteration of mammalian cell metabolism by dynamic nutrient feeding. Cytotechnology 24, 99-108. (Pubitemid 27222172)
-
(1997)
Cytotechnology
, vol.24
, Issue.2
, pp. 99-108
-
-
Zhou, W.1
Rehm, J.2
Europa, A.3
Hu, W.-S.4
-
46
-
-
0344641983
-
An unstructured kinetic model of macromolecular metabolsim in batch and fed-batch cultures of hybridoma cells producing monoclonal antibodies
-
Jang JD, Barford JP (2000) An unstructured kinetic model of macromolecular metabolsim in batch and fed-batch cultures of hybridoma cells producing monoclonal antibodies. Biochem Eng J 4, 153-168.
-
(2000)
Biochem Eng J
, vol.4
, pp. 153-168
-
-
Jang, J.D.1
Barford, J.P.2
-
47
-
-
80053439474
-
Experimental methods and modeling techniques for description of cell population heterogeneity
-
Lencastre Fernandes R, Nierychlo M, Lundin L, Pedersen AE, Puentes Tellez PE, et al. (2011) Experimental methods and modeling techniques for description of cell population heterogeneity. Biotechnol Adv 29, 575-599.
-
(2011)
Biotechnol Adv
, vol.29
, pp. 575-599
-
-
Lencastre Fernandes, R.1
Nierychlo, M.2
Lundin, L.3
Pedersen, A.E.4
Puentes Tellez, P.E.5
-
48
-
-
84855340871
-
A computational approach for understanding and improving gs-ns0 antibody production under hyperosmotic conditions
-
Ho Y, Kiparissides A, Pistikopoulos EN, Mantalaris A (2012) A computational approach for understanding and improving GS-NS0 antibody production under hyperosmotic conditions. J Biosci Bioeng 113,88-98.
-
(2012)
J Biosci Bioeng
, vol.113
, pp. 88-98
-
-
Ho, Y.1
Kiparissides, A.2
Pistikopoulos, E.N.3
Mantalaris, A.4
-
49
-
-
79956206621
-
Closing the loop in biological systems modeling from the in silico to the in vitro
-
Kiparissides A, Koutinas M, Kontoravdi C, Mantalaris A, Pistikopoulos EN (2011) "Closing the loop" in biological systems modeling - from the in silico to the in vitro. Automatica 47, 1147-1155.
-
(2011)
Automatica
, vol.47
, pp. 1147-1155
-
-
Kiparissides, A.1
Koutinas, M.2
Kontoravdi, C.3
Mantalaris, A.4
Pistikopoulos, E.N.5
-
50
-
-
68849103534
-
Global sensitivity analysis challenges in biological systems modeling
-
Kiparissides A, Kucherenko S, Mantalaris A, Pistikopoulos EN (2009) Global sensitivity analysis challenges in biological systems modeling. Ind Eng Chem Res 48, 7168-7180.
-
(2009)
Ind Eng Chem Res
, vol.48
, pp. 7168-7180
-
-
Kiparissides, A.1
Kucherenko, S.2
Mantalaris, A.3
Pistikopoulos, E.N.4
-
52
-
-
77955549294
-
Systematic development of predictive mathematical models for animal cell cultures
-
Kontoravdi C, Pistikopoulos EN, Mantalaris A (2010) Systematic development of predictive mathematical models for animal cell cultures. Comput Chem Eng 34, 1192-1198.
-
(2010)
Comput Chem Eng
, vol.34
, pp. 1192-1198
-
-
Kontoravdi, C.1
Pistikopoulos, E.N.2
Mantalaris, A.3
-
54
-
-
0028011211
-
Optimal experimental design for parameter estimation in unstructured growth models
-
Baltes M, Schneider R, Sturm C, Reuss M (1994) Optimal experimental design for parameter estimation in unstructured growth models. Biotechnol Progr 10, 480-488. (Pubitemid 2151875)
-
(1994)
Biotechnology Progress
, vol.10
, Issue.5
, pp. 480-488
-
-
Baltes, M.1
Schneider, R.2
Sturm, C.3
Reuss, M.4
-
58
-
-
79956011478
-
Improving the prediction of pseudomonas putida mt-2 growth kinetics with the use of a gene expression regulation model of the tol plasmid
-
Koutinas M, Kiparissides A, Lam MC, Silva-Rocha R, Godinho M, et al. (2011) Improving the prediction of Pseudomonas putida mt-2 growth kinetics with the use of a gene expression regulation model of the TOL plasmid. Biochem Eng J 55, 108-118.
-
(2011)
Biochem Eng J
, vol.55
, pp. 108-118
-
-
Koutinas, M.1
Kiparissides, A.2
Lam, M.C.3
Silva-Rocha, R.4
Godinho, M.5
-
59
-
-
61349180117
-
Gene regulatory network inference: Data integration in dynamic models - A review
-
Hecker M, Lambeck S, Toepfer S, van Someren E, Guthke R (2009) Gene regulatory network inference: Data integration in dynamic models - A review. Biosystems 96, 86-103.
-
(2009)
Biosystems
, vol.96
, pp. 86-103
-
-
Hecker, M.1
Lambeck, S.2
Toepfer, S.3
Van Someren, E.4
Guthke, R.5
-
60
-
-
80053384558
-
Mechanistic pathway modeling for industrial biotechnology: Challenging but worthwhile
-
Wiechert W, Noack S (2011) Mechanistic pathway modeling for industrial biotechnology: challenging but worthwhile.Curr Opin Biotechnol 22, 604-610.
-
(2011)
Curr Opin Biotechnol
, vol.22
, pp. 604-610
-
-
Wiechert, W.1
Noack, S.2
-
61
-
-
18844392599
-
Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli
-
DOI 10.1016/j.ymben.2004.12.003, PII S1096717604000849
-
Alper H, Jin YS, Moxley JF, Stephanopoulos G (2005) Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metab Eng 7, 155-164. (Pubitemid 40693564)
-
(2005)
Metabolic Engineering
, vol.7
, Issue.3
, pp. 155-164
-
-
Alper, H.1
Jin, Y.-S.2
Moxley, J.F.3
Stephanopoulos, G.4
-
62
-
-
0036207347
-
Modeling and simulation of genetic regulatory systems: A literature review
-
DOI 10.1089/10665270252833208
-
De Jong H (2002) Modeling and simulation of genetic regulatory systems: A literature review. J Comput Biol 9, 67-103. (Pubitemid 34264287)
-
(2002)
Journal of Computational Biology
, vol.9
, Issue.1
, pp. 67-103
-
-
De Jong, H.1
-
63
-
-
9644302351
-
Splitting the dynamics of large biochemical interaction networks
-
DOI 10.1016/j.jtbi.2004.08.018, PII S002251930400400X
-
Pecou E (2005) Splitting the dynamics of large biochemical interaction networks. J Theor Biol 232, 375-384. (Pubitemid 39575108)
-
(2005)
Journal of Theoretical Biology
, vol.232
, Issue.3
, pp. 375-384
-
-
Pecou, E.1
-
64
-
-
0035319006
-
Computational studies of gene regulatory networks: In numero molecular biology
-
DOI 10.1038/35066056
-
Hasty J, McMillen D, Isaacs F, Collins JJ (2001) Computational studies of gene regulatory networks: in numero molecular biology. Nat Rev 2, 268-279. (Pubitemid 33674775)
-
(2001)
Nature Reviews Genetics
, vol.2
, Issue.4
, pp. 268-279
-
-
Hasty, J.1
McMillen, D.2
Isaacs, F.3
Collins, J.J.4
-
65
-
-
51749113592
-
Integrating metabolic, transcriptional regulatory and signal transduction models in escherichia coli
-
Covert MW, Xiao N, Chen TJ, Karr JR (2008) Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli. Bioinformatics 24, 2044-2050.
-
(2008)
Bioinformatics
, vol.24
, pp. 2044-2050
-
-
Covert, M.W.1
Xiao, N.2
Chen, T.J.3
Karr, J.R.4
-
66
-
-
44949247269
-
Dynamic analysis of integrated signaling, metabolic, and regulatory networks
-
Lee JM, Gianchandani EP, Eddy JA, Papin JA (2008) Dynamic analysis of integrated signaling, metabolic, and regulatory networks. PLoS Comput Biol 4, el000086.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Lee, J.M.1
Gianchandani, E.P.2
Eddy, J.A.3
Papin, J.A.4
-
67
-
-
0035206064
-
The organization of metabolic reaction networks. III. Application for diauxic growth on glucose and lactose
-
DOI 10.1006/mben.2001.0199
-
Kremling A, Bettenbrock K, Laube B, Jahreis K, Lengeler JW, et al. (2001) The organization of metabolic reaction networks III. Application of diauxic growth on glucose and lactose. Metab Eng 3, 362-379. (Pubitemid 33136385)
-
(2001)
Metabolic Engineering
, vol.3
, Issue.4
, pp. 362-379
-
-
Kremling, A.1
Bettenbrock, K.2
Laube, B.3
Jahreis, K.4
Lengeler, J.W.5
Gilles, E.D.6
-
68
-
-
77954306424
-
Intracellular metabolite determination in the presence of extracellular abundance: Application of the penicillin biosynthesis pathway in penicillium chrysogenum
-
Douma RD, Verheijen PJT, de Laat WTAM, Heijnen JJ, van Gulik WM (2010) Intracellular metabolite determination in the presence of extracellular abundance: application of the penicillin biosynthesis pathway in penicillium chrysogenum. Biotechnol Bioeng 106, 608-618.
-
(2010)
Biotechnol Bioeng
, vol.106
, pp. 608-618
-
-
Douma, R.D.1
Verheijen, P.J.T.2
De Laat, W.T.A.M.3
Heijnen, J.J.4
Van Gulik, W.M.5
-
69
-
-
79958723410
-
Linking genes to microbial growth kinetics an integrated biochemical systems engineering approach
-
Koutinas M, Kiparissides A, Silva-Rocha R, Lam MC, dos Santos VAPM, et al. (2011) Linking genes to microbial growth kinetics - An integrated biochemical systems engineering approach. Metab Eng 13,401-413.
-
(2011)
Metab Eng
, vol.13
, pp. 401-413
-
-
Koutinas, M.1
Kiparissides, A.2
Silva-Rocha, R.3
Lam, M.C.4
Dos Santos, V.A.P.M.5
-
70
-
-
0037079012
-
Engineered gene circuits
-
DOI 10.1038/nature01257
-
Hasty J, McMillen D, Collins JJ (2002) Engineered gene circuits. Nature 420, 224-230. (Pubitemid 35340134)
-
(2002)
Nature
, vol.420
, Issue.6912
, pp. 224-230
-
-
Hasty, J.1
McMillen, D.2
Collins, J.J.3
-
71
-
-
0021531796
-
Genetically structured models for lac promoter-operator function in the Escherichia coli chromosome and in multicopy plasmids: Iac operator function
-
DOI 10.1002/bit.260261115
-
Lee SB, Bailey JE (1984) Genetically structured models for lac promoter-operator function in the Escherichia coli chromosome and in multicopy plasmids - lac operator function. Biotechnol Bioeng 26, 1372-1382. (Pubitemid 15224161)
-
(1984)
Biotechnology and Bioengineering
, vol.26
, Issue.11
, pp. 1372-1382
-
-
Lee, S.B.1
Bailey, J.E.2
-
72
-
-
0038271880
-
Prediction and measurement of an autoregulatory genetic module
-
DOI 10.1073/pnas.1332628100
-
Isaacs FJ, Hasty J, Cantor CR, Collins JJ (2003) Prediction and measurement of an autoregulatory genetic module. Proc Natl Acad SciUS A 100, 7714-7719. (Pubitemid 36760035)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.13
, pp. 7714-7719
-
-
Isaacs, F.J.1
Hasty, J.2
Cantor, C.R.3
Collins, J.J.4
-
73
-
-
24044444531
-
The circadian timekeeping system of drosophila
-
DOI 10.1016/j.cub.2005.08.019, PII S0960982205009395
-
Hardin PE (2005) The circadian timekeeping system of Drosophila. Curr Biol 15, R714-R722. (Pubitemid 41219588)
-
(2005)
Current Biology
, vol.15
, Issue.17
-
-
Hardin, P.E.1
-
75
-
-
0034688173
-
A synthetic oscillatory network of transcriptional regulators
-
DOI 10.1038/35002125
-
Elowitz MB, Leibler S (2000) A synthetic oscillatory network of transcriptional regulators. Nature 403, 335-338. (Pubitemid 30062393)
-
(2000)
Nature
, vol.403
, Issue.6767
, pp. 335-338
-
-
Elowitz, M.B.1
Leibier, S.2
-
76
-
-
77953913430
-
Application of mechanistic models to fermentation and biocatalysis for next-generation processes
-
Gernaey KV, Lantz AE, Tufvesson P, Woodley JM, Sin G (2010) Application of mechanistic models to fermentation and biocatalysis for next-generation processes. Trends Biotechnol 28, 346-354.
-
(2010)
Trends Biotechnol
, vol.28
, pp. 346-354
-
-
Gernaey, K.V.1
Lantz, A.E.2
Tufvesson, P.3
Woodley, J.M.4
Sin, G.5
-
77
-
-
77951681944
-
Functional motifs in biochemical reaction networks
-
Tyson JJ, Novak B (2010) Functional motifs in biochemical reaction networks. Annu Rev Phys Chem 61, 219-240.
-
(2010)
Annu Rev Phys Chem
, vol.61
, pp. 219-240
-
-
Tyson, J.J.1
Novak, B.2
-
78
-
-
0036590895
-
Metabolic engineering: Perspective of a chemical engineer
-
DOI 10.1002/aic.690480502
-
Stephanopoulos G (2002) Metabolic engineering: perspective of a chemical engineer. AIChE J 48, 920-926. (Pubitemid 36173038)
-
(2002)
AIChE Journal
, vol.48
, Issue.5
, pp. 920-926
-
-
Stephanopoulos, G.1
-
79
-
-
77954862055
-
Bioprocesses: Modeling needs for process evaluation and sustainability assessment
-
Jimenez-Gonzalez C, Woodley JM (2010) Bioprocesses: Modeling needs for process evaluation and sustainability assessment. Comput ChemEng34, 1009-1017.
-
(2010)
Comput Chem Eng
, vol.34
, pp. 1009-1017
-
-
Jimenez-Gonzalez, C.1
Woodley, J.M.2
|