Use of glucose consumption rate (GCR) as a tool to monitor and control animal cell production processes in packed-bed bioreactors

Journal of Biotechnology

Volumn 122, Issue 1, 2006, Pages 122-129

  Meuwly, F ^a   Papp, F ^a   Ruffieux, P A ^b   Bernard, A R ^a   Kadouri, A ^a   Von Stockar, U ^c  

^a MERCK SERONO S A   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c EPFL   (Switzerland)

Author keywords

Bioreactor; CHO; Fibra Cel ; Glucose consumption rate; Packed bed; Perfusion

Indexed keywords

BIOREACTORS; CELLS; GLUCOSE; MONITORING; TEMPERATURE DISTRIBUTION;

CHO; FIBRA-CEL®; GLUCOSE CONSUMPTION RATE; PACKED-BED; PERFUSION;

CELL CULTURE;

GLUCOSE; LACTIC ACID;

ANIMAL CELL; ARTICLE; BIOREACTOR; CELL CULTURE; CELL DENSITY; CELL GROWTH; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; REPRODUCIBILITY; TEMPERATURE;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; GLUCOSE; INDUSTRIAL MICROBIOLOGY; METABOLIC CLEARANCE RATE; MONITORING, PHYSIOLOGIC;

ANIMALIA;

EID: 32644463328     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2005.08.005     Document Type: Article

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