β-caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 mice through CB2 receptor activation and the PPARγ pathway

Pharmacology

Volumn 94, Issue 1-2, 2014, Pages 1-12

  Cheng, Yujie ^a   Dong, Zhi ^a   Liu, Sha ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Cannabinoid receptor 2; Neuroinflammation; Peroxisome proliferator activated receptor ; Caryophyllene

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; AMYLOID BETA PROTEIN; CANNABINOID 2 RECEPTOR; CARYOPHYLLENE; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TUMOR NECROSIS FACTOR ALPHA; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; NONSTEROID ANTIINFLAMMATORY AGENT; PRESENILIN 1; SESQUITERPENE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTOSIS; BRAIN CORTEX; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MEMORY DISORDER; MICROGLIA; MORNING DOSAGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; COGNITION DISORDERS; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

ADMINISTRATION, ORAL; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CEREBRAL CORTEX; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; INTERLEUKIN-1BETA; MALE; MICE; MICE, TRANSGENIC; PPAR GAMMA; PRESENILIN-1; RECEPTOR, CANNABINOID, CB2; RNA, MESSENGER; SESQUITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84906630766     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000362689     Document Type: Article

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