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Volumn 29, Issue 12, 2008, Pages 1894-1901

Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats

Author keywords

Activated microglia; Aging; Cannabinoid receptors; Inflammation; Spatial memory

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR;

EID: 53649083332     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2007.04.028     Document Type: Article
Times cited : (68)

References (44)
  • 3
    • 0348010292 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains
    • Benito C., Nunez E., Tolon R.M., Carrier E.J., Rabano A., Hillard C.J., and Romero J. Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains. J. Neurosci. 23 (2003) 11136-11141
    • (2003) J. Neurosci. , vol.23 , pp. 11136-11141
    • Benito, C.1    Nunez, E.2    Tolon, R.M.3    Carrier, E.J.4    Rabano, A.5    Hillard, C.J.6    Romero, J.7
  • 6
    • 27744460312 scopus 로고    scopus 로고
    • The synthetic cannabinoid R(+)WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner
    • Curran N.M., Griffin B.D., O'Toole D., Brady K.J., Fitzgerald S.N., and Moynagh P.N. The synthetic cannabinoid R(+)WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner. J. Biol. Chem. 280 (2005) 35797-35806
    • (2005) J. Biol. Chem. , vol.280 , pp. 35797-35806
    • Curran, N.M.1    Griffin, B.D.2    O'Toole, D.3    Brady, K.J.4    Fitzgerald, S.N.5    Moynagh, P.N.6
  • 7
    • 0037440415 scopus 로고    scopus 로고
    • Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide
    • Facchinetti F., Del Giudice E., Furegato S., Passarotto M., and Leon A. Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide. Glia 41 (2003) 161-168
    • (2003) Glia , vol.41 , pp. 161-168
    • Facchinetti, F.1    Del Giudice, E.2    Furegato, S.3    Passarotto, M.4    Leon, A.5
  • 10
    • 0035004146 scopus 로고    scopus 로고
    • Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate neurotoxicity
    • Hampson A.J., and Grimaldi M. Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate neurotoxicity. Eur. J. Neurosci. 13 (2001) 1529-1536
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 1529-1536
    • Hampson, A.J.1    Grimaldi, M.2
  • 11
    • 0032509740 scopus 로고    scopus 로고
    • Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease
    • Hauss-Wegrzyniak B., Dobrzanski P., Stoehr J.D., and Wenk G.L. Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease. Brain Res. 780 (1998) 294-303
    • (1998) Brain Res. , vol.780 , pp. 294-303
    • Hauss-Wegrzyniak, B.1    Dobrzanski, P.2    Stoehr, J.D.3    Wenk, G.L.4
  • 12
    • 0033133362 scopus 로고    scopus 로고
    • The effects of a novel NSAID upon chronic neuroinflammation are age dependent
    • Hauss-Wegrzyniak B., Vraniak P., and Wenk G.L. The effects of a novel NSAID upon chronic neuroinflammation are age dependent. Neurobiol. Aging 20 (1999) 305-313
    • (1999) Neurobiol. Aging , vol.20 , pp. 305-313
    • Hauss-Wegrzyniak, B.1    Vraniak, P.2    Wenk, G.L.3
  • 13
    • 0345621691 scopus 로고    scopus 로고
    • Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
    • Katona I., Sperlagh B., Sik A., Kafalvi A., Vizi E.S., Mackie K., and Freund T.F. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. J. Neurosci. 9 (1999) 4544-4558
    • (1999) J. Neurosci. , vol.9 , pp. 4544-4558
    • Katona, I.1    Sperlagh, B.2    Sik, A.3    Kafalvi, A.4    Vizi, E.S.5    Mackie, K.6    Freund, T.F.7
  • 15
    • 25444495866 scopus 로고    scopus 로고
    • Microglia in health and disease
    • Kim S.U., and de Vellis J. Microglia in health and disease. J. Neurosci. Res. 81 (2005) 302-313
    • (2005) J. Neurosci. Res. , vol.81 , pp. 302-313
    • Kim, S.U.1    de Vellis, J.2
  • 17
    • 18844400058 scopus 로고    scopus 로고
    • Cannabinoid-based drugs as anti-inflammatory therapeutics
    • Klein T.W. Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat. Rev. Immunol. 5 (2005) 400-411
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 400-411
    • Klein, T.W.1
  • 19
    • 33846335526 scopus 로고    scopus 로고
    • Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation
    • Marchalant Y., Rosi S., and Wenk G.L. Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation. Neuroscience 144 (2007) 1516-1522
    • (2007) Neuroscience , vol.144 , pp. 1516-1522
    • Marchalant, Y.1    Rosi, S.2    Wenk, G.L.3
  • 21
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., and Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365 (1993) 61-65
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 22
    • 0034577769 scopus 로고    scopus 로고
    • Memory traces revisited
    • Nadel L., and Land C. Memory traces revisited. Nat. Rev. Neurosci. 1 (2000) 209-212
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 209-212
    • Nadel, L.1    Land, C.2
  • 23
    • 0033561159 scopus 로고    scopus 로고
    • Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures
    • Nagayama T., Sinor A.D., Simon R.P., Chen J., Graham S.H., Jin K., and Greenberg D.A. Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J. Neurosci. 19 (1999) 2987-2995
    • (1999) J. Neurosci. , vol.19 , pp. 2987-2995
    • Nagayama, T.1    Sinor, A.D.2    Simon, R.P.3    Chen, J.4    Graham, S.H.5    Jin, K.6    Greenberg, D.A.7
  • 25
    • 0037111836 scopus 로고    scopus 로고
    • Increased severity of stroke in CB1 cannabinoid receptor knock-out mice
    • Parmentier-Batteur S., Jin K., Mao X.O., Xie L., and Greenberg D.A. Increased severity of stroke in CB1 cannabinoid receptor knock-out mice. J. Neurosci. 22 (2002) 9771-9775
    • (2002) J. Neurosci. , vol.22 , pp. 9771-9775
    • Parmentier-Batteur, S.1    Jin, K.2    Mao, X.O.3    Xie, L.4    Greenberg, D.A.5
  • 26
    • 0027352040 scopus 로고
    • Altered antigen expression of microglia in the aged rodent CNS
    • Perry V.H., Matyszak M.K., and Fearn S. Altered antigen expression of microglia in the aged rodent CNS. Glia 7 (1993) 60-67
    • (1993) Glia , vol.7 , pp. 60-67
    • Perry, V.H.1    Matyszak, M.K.2    Fearn, S.3
  • 27
    • 84884474728 scopus 로고    scopus 로고
    • Pharmacological actions of cannabinoids
    • Pertwee R.G. Pharmacological actions of cannabinoids. Handbook Exp. Pharmacol. 168 (2005) 1-51
    • (2005) Handbook Exp. Pharmacol. , vol.168 , pp. 1-51
    • Pertwee, R.G.1
  • 28
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signaling
    • Piomelli D. The molecular logic of endocannabinoid signaling. Nat. Rev. Neurosci. 4 (2003) 873-884
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 873-884
    • Piomelli, D.1
  • 30
    • 14244264502 scopus 로고    scopus 로고
    • Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation
    • Ramirez B.G., Blazquez C., Gomez del Pulgar T., Guzman M., and de Ceballos M.L. Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation. J. Neurosci. 25 (2005) 1904-1913
    • (2005) J. Neurosci. , vol.25 , pp. 1904-1913
    • Ramirez, B.G.1    Blazquez, C.2    Gomez del Pulgar, T.3    Guzman, M.4    de Ceballos, M.L.5
  • 32
    • 33750353034 scopus 로고    scopus 로고
    • Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat
    • Rosi S., Vazdarjanova A., Ramirez-Amaya V., Worley P.F., Barnes C.A., and Wenk G.L. Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat. Neuroscience 142 (2006) 1303-1315
    • (2006) Neuroscience , vol.142 , pp. 1303-1315
    • Rosi, S.1    Vazdarjanova, A.2    Ramirez-Amaya, V.3    Worley, P.F.4    Barnes, C.A.5    Wenk, G.L.6
  • 33
    • 13244283049 scopus 로고    scopus 로고
    • Synthetic cannabinoid WIN55,212-2 inhibits generation of inflammatory mediators by IL-1β-stimulated human Astrocytes
    • Sheng W.S., Hu S., Min X., Cabral G.A., Lokensgard J.R., and Peterson P.K. Synthetic cannabinoid WIN55,212-2 inhibits generation of inflammatory mediators by IL-1β-stimulated human Astrocytes. Glia 49 (2005) 211-219
    • (2005) Glia , vol.49 , pp. 211-219
    • Sheng, W.S.1    Hu, S.2    Min, X.3    Cabral, G.A.4    Lokensgard, J.R.5    Peterson, P.K.6
  • 35
    • 9644268887 scopus 로고    scopus 로고
    • Cannabinoid signaling in glial cells
    • Stella N. Cannabinoid signaling in glial cells. Glia 48 (2004) 267-277
    • (2004) Glia , vol.48 , pp. 267-277
    • Stella, N.1
  • 36
    • 33747877627 scopus 로고    scopus 로고
    • Microglial senescence: does the brain's immune system have an expiration date?
    • Streit W.J. Microglial senescence: does the brain's immune system have an expiration date?. Trends Neurosci. 29 (2006) 506-510
    • (2006) Trends Neurosci. , vol.29 , pp. 506-510
    • Streit, W.J.1
  • 37
    • 33746779447 scopus 로고    scopus 로고
    • The CB1 cannabinoid receptor mediates glutamatergic synaptic suppression in the hippocampus
    • Takahashi K.A., and Castillo P.E. The CB1 cannabinoid receptor mediates glutamatergic synaptic suppression in the hippocampus. Neuroscience 139 (2006) 795-802
    • (2006) Neuroscience , vol.139 , pp. 795-802
    • Takahashi, K.A.1    Castillo, P.E.2
  • 38
    • 34250175114 scopus 로고    scopus 로고
    • Depression of glutamate and GABA release by presynaptic GABA(B) receptors in the entorhinal cortex in normal and chronically epileptic rats
    • Thompson S.E., Ayman G., Woodhall G.L., and Jones R.S. Depression of glutamate and GABA release by presynaptic GABA(B) receptors in the entorhinal cortex in normal and chronically epileptic rats. Neurosignals 5 (2007) 202-215
    • (2007) Neurosignals , vol.5 , pp. 202-215
    • Thompson, S.E.1    Ayman, G.2    Woodhall, G.L.3    Jones, R.S.4
  • 39
    • 0031929438 scopus 로고    scopus 로고
    • Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
    • Tsou K., Brown S., Sanudo-Pena M.C., Mackie K., and Walker J.M. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83 (1998) 393-411
    • (1998) Neuroscience , vol.83 , pp. 393-411
    • Tsou, K.1    Brown, S.2    Sanudo-Pena, M.C.3    Mackie, K.4    Walker, J.M.5
  • 41
    • 0032982520 scopus 로고    scopus 로고
    • The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells
    • Waksman Y., Olson J., Carlisle S.J., and Cabral G.A. The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells. J. Pharmacol. Exp. Ther. 288 (1999) 1357-1366
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 1357-1366
    • Waksman, Y.1    Olson, J.2    Carlisle, S.J.3    Cabral, G.A.4
  • 42
    • 0037036436 scopus 로고    scopus 로고
    • Astrocytes in culture produce anandamide and other acylethanolamides
    • Walter L., Franklin A., Witting A., Moller T., and Stella N. Astrocytes in culture produce anandamide and other acylethanolamides. J. Biol. Chem. 277 (2002) 20869-20876
    • (2002) J. Biol. Chem. , vol.277 , pp. 20869-20876
    • Walter, L.1    Franklin, A.2    Witting, A.3    Moller, T.4    Stella, N.5
  • 43
    • 0034575607 scopus 로고    scopus 로고
    • Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat
    • Wenk G.L., and Barnes C.A. Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat. Brain Res. 885 (2000) 1-5
    • (2000) Brain Res. , vol.885 , pp. 1-5
    • Wenk, G.L.1    Barnes, C.A.2
  • 44
    • 33748296153 scopus 로고    scopus 로고
    • Potential role of NMDA receptors as executors of neurodegeneration resulting from diverse insults-focus on memantine
    • Wenk G.L., Parson C., and Danysz W. Potential role of NMDA receptors as executors of neurodegeneration resulting from diverse insults-focus on memantine. Behav. Pharmacol. 17 (2006) 411-424
    • (2006) Behav. Pharmacol. , vol.17 , pp. 411-424
    • Wenk, G.L.1    Parson, C.2    Danysz, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.