The Red Queen's long race: Human adaptation to pathogen pressure

Current Opinion in Genetics and Development

Volumn 29, Issue , 2014, Pages 31-38

  Siddle, Katherine J ^a,b   Quintana Murci, Lluis ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; AGRICULTURAL PROCEDURES; EVOLUTIONARY ADAPTATION; GENETIC CORRELATION; GENETIC VARIABILITY; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMAN GENOME; IMMUNE RESPONSE GENE; IMMUNOPATHOLOGY; INFECTION RESISTANCE; INTROGRESSION; MICROBIOLOGICAL PARAMETERS; NATURAL SELECTION; NONHUMAN; PATHOGEN LOAD; PATHOGEN PRESSURE; PHENOTYPE; POPULATION GENETICS; PRIORITY JOURNAL; REVIEW; ADAPTATION; ARTICLE; GENE FREQUENCY; GENETIC ASSOCIATION; HAPLOTYPE; HETEROZYGOSITY; HYPOTHESIS; LIFE EXPECTANCY; PURIFICATION; QUANTITATIVE TRAIT LOCUS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; DISEASE RESISTANCE; ENVIRONMENT; GENETIC SELECTION; GENETICS; MOLECULAR EVOLUTION; REPRODUCTIVE FITNESS;

MYELOID DIFFERENTIATION FACTOR 88; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TOLL LIKE RECEPTOR;

ADAPTATION, PHYSIOLOGICAL; ADAPTIVE IMMUNITY; DISEASE RESISTANCE; ENVIRONMENT; EVOLUTION, MOLECULAR; GENETIC FITNESS; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, GENETIC; SELECTION, GENETIC;

EID: 84906495824     PISSN: 0959437X     EISSN: 18790380     Source Type: Journal    
DOI: 10.1016/j.gde.2014.07.004     Document Type: Review

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