-
1
-
-
72849122933
-
From evolutionary genetics to human immunology: How selection shapes host defence genes
-
L.B. Barreiro, and L. Quintana-Murci From evolutionary genetics to human immunology: how selection shapes host defence genes Nat. Rev. Genet. 11 2010 17 30
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 17-30
-
-
Barreiro, L.B.1
Quintana-Murci, L.2
-
3
-
-
35349012592
-
Genome-wide detection and characterization of positive selection in human populations
-
International HapMap Consortium
-
P.C. Sabeti, P. Varilly, B. Fry, J. Lohmueller, E. Hostetter, C. Cotsapas, X. Xie, E.H. Byrne, S.A. McCarroll, R. Gaudet International HapMap Consortium Genome-wide detection and characterization of positive selection in human populations Nature 449 2007 913 918
-
(2007)
Nature
, vol.449
, pp. 913-918
-
-
Sabeti, P.C.1
Varilly, P.2
Fry, B.3
Lohmueller, J.4
Hostetter, E.5
Cotsapas, C.6
Xie, X.7
Byrne, E.H.8
McCarroll, S.A.9
Gaudet, R.10
-
4
-
-
27544437635
-
Genomic scans for selective sweeps using SNP data
-
R. Nielsen, S. Williamson, Y. Kim, M.J. Hubisz, A.G. Clark, and C. Bustamante Genomic scans for selective sweeps using SNP data Genome Res. 15 2005 1566 1575
-
(2005)
Genome Res.
, vol.15
, pp. 1566-1575
-
-
Nielsen, R.1
Williamson, S.2
Kim, Y.3
Hubisz, M.J.4
Clark, A.G.5
Bustamante, C.6
-
5
-
-
39749136156
-
Natural selection has driven population differentiation in modern humans
-
L.B. Barreiro, G. Laval, H. Quach, E. Patin, and L. Quintana-Murci Natural selection has driven population differentiation in modern humans Nat. Genet. 40 2008 340 345
-
(2008)
Nat. Genet.
, vol.40
, pp. 340-345
-
-
Barreiro, L.B.1
Laval, G.2
Quach, H.3
Patin, E.4
Quintana-Murci, L.5
-
6
-
-
66049157487
-
Signals of recent positive selection in a worldwide sample of human populations
-
J.K. Pickrell, G. Coop, J. Novembre, S. Kudaravalli, J.Z. Li, D. Absher, B.S. Srinivasan, G.S. Barsh, R.M. Myers, M.W. Feldman, and J.K. Pritchard Signals of recent positive selection in a worldwide sample of human populations Genome Res. 19 2009 826 837
-
(2009)
Genome Res.
, vol.19
, pp. 826-837
-
-
Pickrell, J.K.1
Coop, G.2
Novembre, J.3
Kudaravalli, S.4
Li, J.Z.5
Absher, D.6
Srinivasan, B.S.7
Barsh, G.S.8
Myers, R.M.9
Feldman, M.W.10
Pritchard, J.K.11
-
7
-
-
77649213893
-
Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach
-
M. Fumagalli, U. Pozzoli, R. Cagliani, G.P. Comi, N. Bresolin, M. Clerici, and M. Sironi Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach PLoS Genet. 6 2010 e1000849
-
(2010)
PLoS Genet.
, vol.6
, pp. 1000849
-
-
Fumagalli, M.1
Pozzoli, U.2
Cagliani, R.3
Comi, G.P.4
Bresolin, N.5
Clerici, M.6
Sironi, M.7
-
8
-
-
81755177812
-
Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution
-
M. Fumagalli, M. Sironi, U. Pozzoli, A. Ferrer-Admetlla, L. Pattini, and R. Nielsen Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution PLoS Genet. 7 2011 e1002355
-
(2011)
PLoS Genet.
, vol.7
, pp. 1002355
-
-
Fumagalli, M.1
Sironi, M.2
Pozzoli, U.3
Ferrer-Admetlla, A.4
Pattini, L.5
Nielsen, R.6
-
9
-
-
77957879688
-
Extreme evolutionary disparities seen in positive selection across seven complex diseases
-
E. Corona, J.T. Dudley, and A.J. Butte Extreme evolutionary disparities seen in positive selection across seven complex diseases PLoS ONE 5 2010 e12236
-
(2010)
PLoS ONE
, vol.5
, pp. 12236
-
-
Corona, E.1
Dudley, J.T.2
Butte, A.J.3
-
10
-
-
79851478724
-
Genome-wide association study SNPs in the human genome diversity project populations: Does selection affect unlinked SNPs with shared trait associations?
-
A.M. Casto, and M.W. Feldman Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? PLoS Genet. 7 2011 e1001266
-
(2011)
PLoS Genet.
, vol.7
, pp. 1001266
-
-
Casto, A.M.1
Feldman, M.W.2
-
11
-
-
33745121154
-
Positive natural selection in the human lineage
-
P.C. Sabeti, S.F. Schaffner, B. Fry, J. Lohmueller, P. Varilly, O. Shamovsky, A. Palma, T.S. Mikkelsen, D. Altshuler, and E.S. Lander Positive natural selection in the human lineage Science 312 2006 1614 1620
-
(2006)
Science
, vol.312
, pp. 1614-1620
-
-
Sabeti, P.C.1
Schaffner, S.F.2
Fry, B.3
Lohmueller, J.4
Varilly, P.5
Shamovsky, O.6
Palma, A.7
Mikkelsen, T.S.8
Altshuler, D.9
Lander, E.S.10
-
12
-
-
35348988170
-
Recent and ongoing selection in the human genome
-
R. Nielsen, I. Hellmann, M. Hubisz, C. Bustamante, and A.G. Clark Recent and ongoing selection in the human genome Nat. Rev. Genet. 8 2007 857 868
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 857-868
-
-
Nielsen, R.1
Hellmann, I.2
Hubisz, M.3
Bustamante, C.4
Clark, A.G.5
-
13
-
-
33644522070
-
Searching for signals of evolutionary selection in 168 genes related to immune function
-
E.C. Walsh, P. Sabeti, H.B. Hutcheson, B. Fry, S.F. Schaffner, P.I. de Bakker, P. Varilly, A.A. Palma, J. Roy, and R. Cooper Searching for signals of evolutionary selection in 168 genes related to immune function Hum. Genet. 119 2006 92 102
-
(2006)
Hum. Genet.
, vol.119
, pp. 92-102
-
-
Walsh, E.C.1
Sabeti, P.2
Hutcheson, H.B.3
Fry, B.4
Schaffner, S.F.5
De Bakker, P.I.6
Varilly, P.7
Palma, A.A.8
Roy, J.9
Cooper, R.10
-
14
-
-
0036911353
-
Interrogating a high-density SNP map for signatures of natural selection
-
J.M. Akey, G. Zhang, K. Zhang, L. Jin, and M.D. Shriver Interrogating a high-density SNP map for signatures of natural selection Genome Res. 12 2002 1805 1814
-
(2002)
Genome Res.
, vol.12
, pp. 1805-1814
-
-
Akey, J.M.1
Zhang, G.2
Zhang, K.3
Jin, L.4
Shriver, M.D.5
-
15
-
-
65149103048
-
Constructing genomic maps of positive selection in humans: Where do we go from here?
-
J.M. Akey Constructing genomic maps of positive selection in humans: where do we go from here? Genome Res. 19 2009 711 722
-
(2009)
Genome Res.
, vol.19
, pp. 711-722
-
-
Akey, J.M.1
-
16
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
A. Franke, D.P. McGovern, J.C. Barrett, K. Wang, G.L. Radford-Smith, T. Ahmad, C.W. Lees, T. Balschun, J. Lee, and R. Roberts Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci Nat. Genet. 42 2010 1118 1125
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
Lees, C.W.7
Balschun, T.8
Lee, J.9
Roberts, R.10
-
17
-
-
65949120185
-
The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection
-
B. Carlsson, E. Kindberg, J. Buesa, G.E. Rydell, M.F. Lidón, R. Montava, R. Abu Mallouh, A. Grahn, J. Rodríguez-Díaz, and J. Bellido The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection PLoS ONE 4 2009 e5593
-
(2009)
PLoS ONE
, vol.4
, pp. 5593
-
-
Carlsson, B.1
Kindberg, E.2
Buesa, J.3
Rydell, G.E.4
Lidón, M.F.5
Montava, R.6
Abu Mallouh, R.7
Grahn, A.8
Rodríguez-Díaz, J.9
Bellido, J.10
-
18
-
-
77953231426
-
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection
-
Finnish Celiac Disease Study Group
-
A. Zhernakova, C.C. Elbers, B. Ferwerda, J. Romanos, G. Trynka, P.C. Dubois, C.G. de Kovel, L. Franke, M. Oosting, D. Barisani Finnish Celiac Disease Study Group Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection Am. J. Hum. Genet. 86 2010 970 977
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 970-977
-
-
Zhernakova, A.1
Elbers, C.C.2
Ferwerda, B.3
Romanos, J.4
Trynka, G.5
Dubois, P.C.6
De Kovel, C.G.7
Franke, L.8
Oosting, M.9
Barisani, D.10
-
19
-
-
0023764283
-
Pattern of nucleotide substitution at major histocompatibility complex class i loci reveals overdominant selection
-
A.L. Hughes, and M. Nei Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection Nature 335 1988 167 170
-
(1988)
Nature
, vol.335
, pp. 167-170
-
-
Hughes, A.L.1
Nei, M.2
-
20
-
-
20144369614
-
Pathogen-driven selection and worldwide HLA class i diversity
-
F. Prugnolle, A. Manica, M. Charpentier, J.F. Guégan, V. Guernier, and F. Balloux Pathogen-driven selection and worldwide HLA class I diversity Curr. Biol. 15 2005 1022 1027
-
(2005)
Curr. Biol.
, vol.15
, pp. 1022-1027
-
-
Prugnolle, F.1
Manica, A.2
Charpentier, M.3
Guégan, J.F.4
Guernier, V.5
Balloux, F.6
-
21
-
-
84857357877
-
Signatures of historical demography and pathogen richness on MHC class i genes
-
N. Qutob, F. Balloux, T. Raj, H. Liu, S. Marion de Procé, J. Trowsdale, and A. Manica Signatures of historical demography and pathogen richness on MHC class I genes Immunogenetics 64 2012 165 175
-
(2012)
Immunogenetics
, vol.64
, pp. 165-175
-
-
Qutob, N.1
Balloux, F.2
Raj, T.3
Liu, H.4
Marion De Procé, S.5
Trowsdale, J.6
Manica, A.7
-
22
-
-
0024417450
-
Hay fever, hygiene, and household size
-
D.P. Strachan Hay fever, hygiene, and household size BMJ 299 1989 1259 1260
-
(1989)
BMJ
, vol.299
, pp. 1259-1260
-
-
Strachan, D.P.1
-
23
-
-
0034241683
-
Family size, infection and atopy: The first decade of the "hygiene hypothesis"
-
D.P. Strachan Family size, infection and atopy: the first decade of the "hygiene hypothesis" Thorax 55 Suppl 1 2000 S2 S10
-
(2000)
Thorax
, vol.55
, Issue.SUPPL. 1
-
-
Strachan, D.P.1
-
24
-
-
79951521421
-
Progress and promise of genome-wide association studies for human complex trait genetics
-
B.E. Stranger, E.A. Stahl, and T. Raj Progress and promise of genome-wide association studies for human complex trait genetics Genetics 187 2011 367 383
-
(2011)
Genetics
, vol.187
, pp. 367-383
-
-
Stranger, B.E.1
Stahl, E.A.2
Raj, T.3
-
25
-
-
70349882120
-
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
-
I. Amit, M. Garber, N. Chevrier, A.P. Leite, Y. Donner, T. Eisenhaure, M. Guttman, J.K. Grenier, W. Li, and O. Zuk Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses Science 326 2009 257 263
-
(2009)
Science
, vol.326
, pp. 257-263
-
-
Amit, I.1
Garber, M.2
Chevrier, N.3
Leite, A.P.4
Donner, Y.5
Eisenhaure, T.6
Guttman, M.7
Grenier, J.K.8
Li, W.9
Zuk, O.10
-
26
-
-
84856387609
-
Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
-
L.B. Barreiro, L. Tailleux, A.A. Pai, B. Gicquel, J.C. Marioni, and Y. Gilad Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection Proc. Natl. Acad. Sci. USA 109 2012 1204 1209
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 1204-1209
-
-
Barreiro, L.B.1
Tailleux, L.2
Pai, A.A.3
Gicquel, B.4
Marioni, J.C.5
Gilad, Y.6
-
27
-
-
79960279940
-
Promise and pitfalls of the Immunochip
-
A. Cortes, and M.A. Brown Promise and pitfalls of the Immunochip Arthritis Res. Ther. 13 2011 101
-
(2011)
Arthritis Res. Ther.
, vol.13
, pp. 101
-
-
Cortes, A.1
Brown, M.A.2
-
28
-
-
0021566877
-
Estimating F-statistics for the analysis of population structure
-
B.S. Weir, and C.C. Cockerham Estimating F-statistics for the analysis of population structure Evolution 38 1984 1358 1370
-
(1984)
Evolution
, vol.38
, pp. 1358-1370
-
-
Weir, B.S.1
Cockerham, C.C.2
-
29
-
-
1842611890
-
Plotting haplotype-specific linkage disequilibrium patterns by extended haplotype homozygosity
-
J.C. Mueller, and C. Andreoli Plotting haplotype-specific linkage disequilibrium patterns by extended haplotype homozygosity Bioinformatics 20 2004 786 787
-
(2004)
Bioinformatics
, vol.20
, pp. 786-787
-
-
Mueller, J.C.1
Andreoli, C.2
-
30
-
-
77956637896
-
Genetics and beyond - The transcriptome of human monocytes and disease susceptibility
-
T. Zeller, P. Wild, S. Szymczak, M. Rotival, A. Schillert, R. Castagne, S. Maouche, M. Germain, K. Lackner, and H. Rossmann Genetics and beyond - the transcriptome of human monocytes and disease susceptibility PLoS ONE 5 2010 e10693
-
(2010)
PLoS ONE
, vol.5
, pp. 10693
-
-
Zeller, T.1
Wild, P.2
Szymczak, S.3
Rotival, M.4
Schillert, A.5
Castagne, R.6
Maouche, S.7
Germain, M.8
Lackner, K.9
Rossmann, H.10
-
31
-
-
58549101103
-
A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
-
K. Lage, N.T. Hansen, E.O. Karlberg, A.C. Eklund, F.S. Roque, P.K. Donahoe, Z. Szallasi, T.S. Jensen, and S. Brunak A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes Proc. Natl. Acad. Sci. USA 105 2008 20870 20875
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20870-20875
-
-
Lage, K.1
Hansen, N.T.2
Karlberg, E.O.3
Eklund, A.C.4
Roque, F.S.5
Donahoe, P.K.6
Szallasi, Z.7
Jensen, T.S.8
Brunak, S.9
-
32
-
-
79851502150
-
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
-
International Inflammatory Bowel Disease Genetics Constortium
-
E.J. Rossin, K. Lage, S. Raychaudhuri, R.J. Xavier, D. Tatar, Y. Benita, C. Cotsapas, M.J. Daly International Inflammatory Bowel Disease Genetics Constortium Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology PLoS Genet. 7 2011 e1001273
-
(2011)
PLoS Genet.
, vol.7
, pp. 1001273
-
-
Rossin, E.J.1
Lage, K.2
Raychaudhuri, S.3
Xavier, R.J.4
Tatar, D.5
Benita, Y.6
Cotsapas, C.7
Daly, M.J.8
-
33
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
International MS Genetics Consortium
-
P.L. De Jager, X. Jia, J. Wang, P.I. de Bakker, L. Ottoboni, N.T. Aggarwal, L. Piccio, S. Raychaudhuri, D. Tran, C. Aubin International MS Genetics Consortium Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci Nat. Genet. 41 2009 776 782
-
(2009)
Nat. Genet.
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
De Bakker, P.I.4
Ottoboni, L.5
Aggarwal, N.T.6
Piccio, L.7
Raychaudhuri, S.8
Tran, D.9
Aubin, C.10
-
34
-
-
34548738566
-
Population genomics of human gene expression
-
B.E. Stranger, A.C. Nica, M.S. Forrest, A. Dimas, C.P. Bird, C. Beazley, C.E. Ingle, M. Dunning, P. Flicek, and D. Koller Population genomics of human gene expression Nat. Genet. 39 2007 1217 1224
-
(2007)
Nat. Genet.
, vol.39
, pp. 1217-1224
-
-
Stranger, B.E.1
Nica, A.C.2
Forrest, M.S.3
Dimas, A.4
Bird, C.P.5
Beazley, C.6
Ingle, C.E.7
Dunning, M.8
Flicek, P.9
Koller, D.10
-
35
-
-
76749097550
-
The genetics of human adaptation: Hard sweeps, soft sweeps, and polygenic adaptation
-
J.K. Pritchard, J.K. Pickrell, and G. Coop The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation Curr. Biol. 20 2010 R208 R215
-
(2010)
Curr. Biol.
, vol.20
-
-
Pritchard, J.K.1
Pickrell, J.K.2
Coop, G.3
-
36
-
-
63749127623
-
Worldwide population differentiation at disease-associated SNPs
-
S. Myles, D. Davison, J. Barrett, M. Stoneking, and N. Timpson Worldwide population differentiation at disease-associated SNPs BMC Med. Genomics 1 2008 22
-
(2008)
BMC Med. Genomics
, vol.1
, pp. 22
-
-
Myles, S.1
Davison, D.2
Barrett, J.3
Stoneking, M.4
Timpson, N.5
-
37
-
-
51049113607
-
InnateDB: Facilitating systems-level analyses of the mammalian innate immune response
-
D.J. Lynn, G.L. Winsor, C. Chan, N. Richard, M.R. Laird, A. Barsky, J.L. Gardy, F.M. Roche, T.H. Chan, and N. Shah InnateDB: facilitating systems-level analyses of the mammalian innate immune response Mol. Syst. Biol. 4 2008 218
-
(2008)
Mol. Syst. Biol.
, vol.4
, pp. 218
-
-
Lynn, D.J.1
Winsor, G.L.2
Chan, C.3
Richard, N.4
Laird, M.R.5
Barsky, A.6
Gardy, J.L.7
Roche, F.M.8
Chan, T.H.9
Shah, N.10
-
38
-
-
80052325959
-
Pervasive sharing of genetic effects in autoimmune disease
-
FOCiS Network of Consortia
-
C. Cotsapas, B.F. Voight, E. Rossin, K. Lage, B.M. Neale, C. Wallace, G.R. Abecasis, J.C. Barrett, T. Behrens, J. Cho FOCiS Network of Consortia Pervasive sharing of genetic effects in autoimmune disease PLoS Genet. 7 2011 e1002254
-
(2011)
PLoS Genet.
, vol.7
, pp. 1002254
-
-
Cotsapas, C.1
Voight, B.F.2
Rossin, E.3
Lage, K.4
Neale, B.M.5
Wallace, C.6
Abecasis, G.R.7
Barrett, J.C.8
Behrens, T.9
Cho, J.10
-
39
-
-
84255194782
-
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci
-
Bayer Pharma MS Genetics Working Group Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist ANZgene Consortium GeneMSA International Multiple Sclerosis Genetics Consortium
-
N.A. Patsopoulos, F. Esposito, J. Reischl, S. Lehr, D. Bauer, J. Heubach, R. Sandbrink, C. Pohl, G. Edan, L. Kappos Bayer Pharma MS Genetics Working Group Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist ANZgene Consortium GeneMSA International Multiple Sclerosis Genetics Consortium Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci Ann. Neurol. 70 2011 897 912
-
(2011)
Ann. Neurol.
, vol.70
, pp. 897-912
-
-
Patsopoulos, N.A.1
Esposito, F.2
Reischl, J.3
Lehr, S.4
Bauer, D.5
Heubach, J.6
Sandbrink, R.7
Pohl, C.8
Edan, G.9
Kappos, L.10
-
40
-
-
33947095027
-
A human phenome-interactome network of protein complexes implicated in genetic disorders
-
K. Lage, E.O. Karlberg, Z.M. Størling, P.I. Olason, A.G. Pedersen, O. Rigina, A.M. Hinsby, Z. Tümer, F. Pociot, and N. Tommerup A human phenome-interactome network of protein complexes implicated in genetic disorders Nat. Biotechnol. 25 2007 309 316
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 309-316
-
-
Lage, K.1
Karlberg, E.O.2
Størling, Z.M.3
Olason, P.I.4
Pedersen, A.G.5
Rigina, O.6
Hinsby, A.M.7
Tümer, Z.8
Pociot, F.9
Tommerup, N.10
-
41
-
-
84859499759
-
Alzheimer disease susceptibility loci: Evidence for a protein network under natural selection
-
T. Raj, J.M. Shulman, B.T. Keenan, L.B. Chibnik, D.A. Evans, D.A. Bennett, B.E. Stranger, and P.L. De Jager Alzheimer disease susceptibility loci: evidence for a protein network under natural selection Am. J. Hum. Genet. 90 2012 720 726
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 720-726
-
-
Raj, T.1
Shulman, J.M.2
Keenan, B.T.3
Chibnik, L.B.4
Evans, D.A.5
Bennett, D.A.6
Stranger, B.E.7
De Jager, P.L.8
-
42
-
-
84860596557
-
Patterns of cis regulatory variation in diverse human populations
-
B.E. Stranger, S.B. Montgomery, A.S. Dimas, L. Parts, O. Stegle, C.E. Ingle, M. Sekowska, G.D. Smith, D. Evans, and M. Gutierrez-Arcelus Patterns of cis regulatory variation in diverse human populations PLoS Genet. 8 2012 e1002639
-
(2012)
PLoS Genet.
, vol.8
, pp. 1002639
-
-
Stranger, B.E.1
Montgomery, S.B.2
Dimas, A.S.3
Parts, L.4
Stegle, O.5
Ingle, C.E.6
Sekowska, M.7
Smith, G.D.8
Evans, D.9
Gutierrez-Arcelus, M.10
-
43
-
-
78149267111
-
Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes
-
A. Murphy, J.H. Chu, M. Xu, V.J. Carey, R. Lazarus, A. Liu, S.J. Szefler, R. Strunk, K. Demuth, and M. Castro Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes Hum. Mol. Genet. 19 2010 4745 4757
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4745-4757
-
-
Murphy, A.1
Chu, J.H.2
Xu, M.3
Carey, V.J.4
Lazarus, R.5
Liu, A.6
Szefler, S.J.7
Strunk, R.8
Demuth, K.9
Castro, M.10
-
44
-
-
70350650472
-
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
-
V. Gateva, J.K. Sandling, G. Hom, K.E. Taylor, S.A. Chung, X. Sun, W. Ortmann, R. Kosoy, R.C. Ferreira, and G. Nordmark A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus Nat. Genet. 41 2009 1228 1233
-
(2009)
Nat. Genet.
, vol.41
, pp. 1228-1233
-
-
Gateva, V.1
Sandling, J.K.2
Hom, G.3
Taylor, K.E.4
Chung, S.A.5
Sun, X.6
Ortmann, W.7
Kosoy, R.8
Ferreira, R.C.9
Nordmark, G.10
-
45
-
-
77956586071
-
LocusZoom: Regional visualization of genome-wide association scan results
-
R.J. Pruim, R.P. Welch, S. Sanna, T.M. Teslovich, P.S. Chines, T.P. Gliedt, M. Boehnke, G.R. Abecasis, and C.J. Willer LocusZoom: regional visualization of genome-wide association scan results Bioinformatics 26 2010 2336 2337
-
(2010)
Bioinformatics
, vol.26
, pp. 2336-2337
-
-
Pruim, R.J.1
Welch, R.P.2
Sanna, S.3
Teslovich, T.M.4
Chines, P.S.5
Gliedt, T.P.6
Boehnke, M.7
Abecasis, G.R.8
Willer, C.J.9
-
46
-
-
77952367694
-
Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations
-
A.C. Nica, S.B. Montgomery, A.S. Dimas, B.E. Stranger, C. Beazley, I. Barroso, and E.T. Dermitzakis Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations PLoS Genet. 6 2010 e1000895
-
(2010)
PLoS Genet.
, vol.6
, pp. 1000895
-
-
Nica, A.C.1
Montgomery, S.B.2
Dimas, A.S.3
Stranger, B.E.4
Beazley, C.5
Barroso, I.6
Dermitzakis, E.T.7
-
48
-
-
85056026779
-
Th17 cells in inflammatory conditions
-
A. Cooke Th17 cells in inflammatory conditions Rev. Diabet. Stud. 3 2006 72 75
-
(2006)
Rev. Diabet. Stud.
, vol.3
, pp. 72-75
-
-
Cooke, A.1
-
49
-
-
60849138547
-
IL-23 and autoimmunity: New insights into the pathogenesis of inflammatory bowel disease
-
C. Abraham, and J.H. Cho IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease Annu. Rev. Med. 60 2009 97 110
-
(2009)
Annu. Rev. Med.
, vol.60
, pp. 97-110
-
-
Abraham, C.1
Cho, J.H.2
-
50
-
-
34247555353
-
Differentiation and function of Th17 T cells
-
B. Stockinger, and M. Veldhoen Differentiation and function of Th17 T cells Curr. Opin. Immunol. 19 2007 281 286
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 281-286
-
-
Stockinger, B.1
Veldhoen, M.2
-
52
-
-
84862695017
-
Th17 cells: Biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies
-
M.S. Maddur, P. Miossec, S.V. Kaveri, and J. Bayry Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies Am. J. Pathol. 181 2012 8 18
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 8-18
-
-
Maddur, M.S.1
Miossec, P.2
Kaveri, S.V.3
Bayry, J.4
-
53
-
-
25144515561
-
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae
-
K.I. Happel, P.J. Dubin, M. Zheng, N. Ghilardi, C. Lockhart, L.J. Quinton, A.R. Odden, J.E. Shellito, G.J. Bagby, S. Nelson, and J.K. Kolls Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae J. Exp. Med. 202 2005 761 769
-
(2005)
J. Exp. Med.
, vol.202
, pp. 761-769
-
-
Happel, K.I.1
Dubin, P.J.2
Zheng, M.3
Ghilardi, N.4
Lockhart, C.5
Quinton, L.J.6
Odden, A.R.7
Shellito, J.E.8
Bagby, G.J.9
Nelson, S.10
Kolls, J.K.11
-
54
-
-
40049098958
-
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
-
S.J. Aujla, Y.R. Chan, M. Zheng, M. Fei, D.J. Askew, D.A. Pociask, T.A. Reinhart, F. McAllister, J. Edeal, and K. Gaus IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia Nat. Med. 14 2008 275 281
-
(2008)
Nat. Med.
, vol.14
, pp. 275-281
-
-
Aujla, S.J.1
Chan, Y.R.2
Zheng, M.3
Fei, M.4
Askew, D.J.5
Pociask, D.A.6
Reinhart, T.A.7
McAllister, F.8
Edeal, J.9
Gaus, K.10
-
55
-
-
40049083827
-
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
-
Y. Zheng, P.A. Valdez, D.M. Danilenko, Y. Hu, S.M. Sa, Q. Gong, A.R. Abbas, Z. Modrusan, N. Ghilardi, F.J. de Sauvage, and W. Ouyang Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens Nat. Med. 14 2008 282 289
-
(2008)
Nat. Med.
, vol.14
, pp. 282-289
-
-
Zheng, Y.1
Valdez, P.A.2
Danilenko, D.M.3
Hu, Y.4
Sa, S.M.5
Gong, Q.6
Abbas, A.R.7
Modrusan, Z.8
Ghilardi, N.9
De Sauvage, F.J.10
Ouyang, W.11
-
56
-
-
78249271381
-
IL-17 in protective immunity to intracellular pathogens
-
S.A. Khader, and R. Gopal IL-17 in protective immunity to intracellular pathogens Virulence 1 2010 423 427
-
(2010)
Virulence
, vol.1
, pp. 423-427
-
-
Khader, S.A.1
Gopal, R.2
-
57
-
-
84857846732
-
An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague
-
A. Derbise, A. Cerda Marin, P. Ave, T. Blisnick, M. Huerre, E. Carniel, and C.E. Demeure An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague PLoS Negl. Trop. Dis. 6 2012 e1528
-
(2012)
PLoS Negl. Trop. Dis.
, vol.6
, pp. 1528
-
-
Derbise, A.1
Cerda Marin, A.2
Ave, P.3
Blisnick, T.4
Huerre, M.5
Carniel, E.6
Demeure, C.E.7
-
58
-
-
79952262073
-
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
-
A. Zhernakova, E.A. Stahl, G. Trynka, S. Raychaudhuri, E.A. Festen, L. Franke, H.J. Westra, R.S. Fehrmann, F.A. Kurreeman, and B. Thomson Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci PLoS Genet. 7 2011 e1002004
-
(2011)
PLoS Genet.
, vol.7
, pp. 1002004
-
-
Zhernakova, A.1
Stahl, E.A.2
Trynka, G.3
Raychaudhuri, S.4
Festen, E.A.5
Franke, L.6
Westra, H.J.7
Fehrmann, R.S.8
Kurreeman, F.A.9
Thomson, B.10
-
59
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
A. Zhernakova, C.C. van Diemen, and C. Wijmenga Detecting shared pathogenesis from the shared genetics of immune-related diseases Nat. Rev. Genet. 10 2009 43 55
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
Van Diemen, C.C.2
Wijmenga, C.3
-
60
-
-
34548805282
-
A genome-wide association study of global gene expression
-
A.L. Dixon, L. Liang, M.F. Moffatt, W. Chen, S. Heath, K.C. Wong, J. Taylor, E. Burnett, I. Gut, and M. Farrall A genome-wide association study of global gene expression Nat. Genet. 39 2007 1202 1207
-
(2007)
Nat. Genet.
, vol.39
, pp. 1202-1207
-
-
Dixon, A.L.1
Liang, L.2
Moffatt, M.F.3
Chen, W.4
Heath, S.5
Wong, K.C.6
Taylor, J.7
Burnett, E.8
Gut, I.9
Farrall, M.10
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