Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 7, 2014, Pages 2668-2673

  Laayouni, Hafid ^a   Oosting, Marije ^b,c   Luisi, Pierre ^a   Ioana, Mihai ^d   Alonso, Santos ^e   Ricano Ponce, Isis ^f   Trynka, Gosia ^f,j,k   Zhernakova, Alexandra ^f   Plantinga, Theo S ^b,c   Cheng, Shih Chin ^b,c   Van Der Meer, Jos W M ^b,c   Popp, Radu ^g   Sood, Ajit ^h   Thelma, B K ⁱ   Wijmenga, Cisca ^f   Joosten, Leo A B ^b,c   Bertranpetit, Jaume ^a   Netea, Mihai G ^b,c  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b Department of Medicine ^*  (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF MEDICINE AND PHARMACY OF CRAIOVA   (Romania)

^e UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^f UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^g IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^h DAYANAND MEDICAL COLLEGE AND HOSPITAL   (India)

ⁱ UNIVERSITY OF DELHI   (India)

^j HARVARD MEDICAL SCHOOL   (United States)

^k MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

more..

Author keywords

Immunity; Migration; Pandemics; Pattern recognition receptors

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 6; TUMOR NECROSIS FACTOR;

ARTICLE; CONVERGENT EVOLUTION; EUROPE; GENE CLUSTER; GENE IDENTIFICATION; GENE PRODUCT; GENETIC ANALYSIS; GIPSY; HUMAN; IMMUNE SYSTEM; IMMUNOGENETICS; NONHUMAN; PLAGUE; POPULATION GENETICS; PRIORITY JOURNAL; ROMANIA; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; YERSINIA PESTIS;

IMMUNITY; MIGRATION; PANDEMICS; PATTERN RECOGNITION RECEPTORS;

ADAPTATION, BIOLOGICAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EUROPEAN CONTINENTAL ANCESTRY GROUP; EVOLUTION, MOLECULAR; GYPSIES; HEK293 CELLS; HUMANS; IMMUNOGENETICS; INDIA; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PRINCIPAL COMPONENT ANALYSIS; ROMANIA; TOLL-LIKE RECEPTORS; YERSINIA PESTIS;

EID: 84894335860     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1317723111     Document Type: Article

References (31)

1. Barreiro LB, Quintana-Murci L (2010) From evolutionary genetics to human immunology: How selection shapes host defence genes. Nat Rev Genet 11(1):17-30.
2. Netea MG, Wijmenga C, O'Neill LA (2012) Genetic variation in Toll-like receptors and disease susceptibility. Nat Immunol 13(6):535-542.
3. Ferrer-Admetlla A, et al. (2008) Balancing selection is the main force shaping the evolution of innate immunity genes. J Immunol 181(2):1315-1322.
4. Stene LC, et al. (2006) Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: A longitudinal study. Am J Gastroenterol 101(10):2333-2340.
5. Zhernakova A, et al.; Finnish Celiac Disease Study Group (2010) Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am J Hum Genet 86(6):970-977.
6. Stephens JC, et al. (1998) Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes. Am J Hum Genet 62(6):1507-1515.
7. Mendizabal I, et al. (2012) Reconstructing the population history of European Romani from genome-wide data. Curr Biol 22(24):2342-2349.
8. Trynka G, et al.; Spanish Consortium on the Genetics of Coeliac Disease (CEGEC); PreventCD Study Group; Wellcome Trust Case Control Consortium (WTCCC) (2011) Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet 43(12):1193-1201.
9. Patterson N, Price AL, Reich D (2006) Population structure and eigenanalysis. PLoS Genet 2(12):e190.
10. Chen H, Patterson N, Reich D (2010) Population differentiation as a test for selective sweeps. Genome Res 20(3):393-402.
11. Bhatia G, et al. (2011) Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. Am J Hum Genet 89(3):368-381.
12. Mi H, Muruganujan A, Thomas PD (2013) PANTHER in 2013: Modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees. Nucleic Acids Res 41(Database issue):D377-D386.
13. Grundberg E, et al.; Multiple Tissue Human Expression Resource (MuTHER) Consortium (2012) Mapping cis-and trans-regulatory effects across multiple tissues in twins. Nat Genet 44(10):1084-1089.
14. Lao O, de Gruijter JM, van Duijn K, Navarro A, Kayser M (2007) Signatures of positive selection in genes associated with human skin pigmentation as revealed from analyses of single nucleotide polymorphisms. Ann Hum Genet 71(Pt 3):354-369.
15. Akey JM (2009) Constructing genomic maps of positive selection in humans: Where do we go from here? Genome Res 19(5):711-722.
16. Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124(4):783-801.
17. Mantovani A, Locati M, Polentarutti N, Vecchi A, Garlanda C (2004) Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: The new entry TIR8/SIGIRR. J Leukoc Biol 75(5):738-742.
18. Abecasis GR, et al.; 1000 Genomes Project Consortium (2012) An integrated map of genetic variation from 1,092 human genomes. Nature 491(7422):56-65.
19. Zhao J, et al. (2012) F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation. Nat Immunol 13(7):651-658.
20. Nah SS, et al. (2012) Association of ADAMTS12 polymorphisms with rheumatoid arthritis. Mol Med Rep 6(1):227-231.
21. Fraser A (1992) The Gypsies (Blackwell, Oxford).
22. McEvedy C (1988) The bubonic plague. Sci Am 258(2):118-123.
23. Takeuchi O, et al. (2002) Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol 169(1):10-14.
24. Abramov VM, et al. (2001) Structural and functional similarity between Yersinia pestis capsular protein Caf1 and human interleukin-1 beta. Biochemistry 40(20):6076-6084.
25. Barreiro LB, et al. (2009) Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet 5(7):e1000562.
26. Sussman GD (2011) Was the black death in India and China? Bull Hist Med 85(3): 319-355.
27. Di Rienzo A (2006) Population genetics models of common diseases. Curr Opin Genet Dev 16(6):630-636.
28. Veltkamp M, van Moorsel CH, Rijkers GT, Ruven HJ, Grutters JC (2012) Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis. Tissue Antigens 79(1):25-32.
29. Abad C, et al. (2011) Association of Toll-like receptor 10 and susceptibility to Crohn's disease independent of NOD2. Genes Immun 12(8):635-642.
30. Sabeti PC, et al.; International HapMap Consortium (2007) Genome-wide detection and characterization of positive selection in human populations. Nature 449(7164):913-918.
31. Oosting M, et al. (2011) TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes. PLoS ONE 6(10):e25998.