Admixture facilitates genetic adaptations to high altitude in Tibet

Nature Communications

Volumn 5, Issue , 2014, Pages

  Jeong, Choongwon ^a   Alkorta Aranburu, Gorka ^a   Basnyat, Buddha ^b   Neupane, Maniraj ^c   Witonsky, David B ^a   Pritchard, Jonathan K ^a,d,f   Beall, Cynthia M ^e   Di Rienzo, Anna ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^c Mountain Medicine Society of Nepal   (Nepal)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

^f STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; EGL NINE HOMOLOGUE 1 PROTEIN; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; HEMOGLOBIN; HYPOXIA UPREGULATED PROTEIN 1; PORPHOBILINOGEN DEAMINASE; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; EGLN1 PROTEIN, HUMAN; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE;

ANCESTRY; BLOOD; CONCENTRATION (COMPOSITION); GENE EXPRESSION; GENETIC ANALYSIS; GENOME; GENOTYPE; INTROGRESSION; MUTATION;

ADMIXTURE; ADULT; ALLELE; ALTITUDE; ARTICLE; CHINA; EVOLUTIONARY ADAPTATION; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC DRIFT; GENETIC VARIABILITY; GENOTYPE; HAN CHINESE; HEMOGLOBIN DETERMINATION; HUMAN; HUMAN GENOME; LOCAL ADAPTATION; MALE; NEPALESE; NORMAL HUMAN; PHENOTYPE; POPULATION AND POPULATION RELATED PHENOMENA; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; TIBETAN (PEOPLE); ADAPTATION; ASIAN CONTINENTAL ANCESTRY GROUP; GENE FLOW; GENETICS; MIDDLE AGED; TIBET; YOUNG ADULT;

CHINA; XIZANG;

ADAPTATION, BIOLOGICAL; ADULT; ALTITUDE; ASIAN CONTINENTAL ANCESTRY GROUP; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; FEMALE; GENE FLOW; HUMANS; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; MALE; MIDDLE AGED; TIBET; YOUNG ADULT;

EID: 84903715029     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4281     Document Type: Article

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