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Volumn 26, Issue 3, 2009, Pages 649-658

Gene expression levels are a target of recent natural selection in the human genome

Author keywords

eQTL mapping; Humans; iHS; Population genetics; Recent positive selection

Indexed keywords

CELL LINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME, HUMAN; HAPLOTYPES; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION (GENETICS);

EID: 60149091864     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msn289     Document Type: Article
Times cited : (77)

References (41)
  • 1
    • 0033624575 scopus 로고    scopus 로고
    • Altshuler D, Hirschhorn J, Klannemark M, et al. (16 co-authors). 2000. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 26:76-80.
    • Altshuler D, Hirschhorn J, Klannemark M, et al. (16 co-authors). 2000. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 26:76-80.
  • 3
    • 34548805282 scopus 로고    scopus 로고
    • Dixon A, Liang L, Moffatt M, et al. (13 co-authors). 2007. A genome-wide association study of global gene expression. Nat Genet. 39:1202-1207.
    • Dixon A, Liang L, Moffatt M, et al. (13 co-authors). 2007. A genome-wide association study of global gene expression. Nat Genet. 39:1202-1207.
  • 4
    • 4644310840 scopus 로고    scopus 로고
    • The genetic variant of lactase persistence C (-13910) T as a risk factor for type I and II diabetes in the Finnish population
    • Enattah N, Forsblom C, Rasinper H, Tuomi T, Groop P, Jrvel I. 2004. The genetic variant of lactase persistence C (-13910) T as a risk factor for type I and II diabetes in the Finnish population. Eur J Clin Nutr. 58:1319-1322.
    • (2004) Eur J Clin Nutr , vol.58 , pp. 1319-1322
    • Enattah, N.1    Forsblom, C.2    Rasinper, H.3    Tuomi, T.4    Groop, P.5    Jrvel, I.6
  • 5
    • 34548134145 scopus 로고    scopus 로고
    • Fellay J, Shianna K, Ge D, et al. (27 co-authors). 2007. A whole-genome association study of major determinants for host control of HIV-1. Science. 317:944-947.
    • Fellay J, Shianna K, Ge D, et al. (27 co-authors). 2007. A whole-genome association study of major determinants for host control of HIV-1. Science. 317:944-947.
  • 6
    • 47249142778 scopus 로고    scopus 로고
    • Revealing the architecture of gene regulation: The promise of eQTL studies
    • Gilad Y, Rifkin S, Pritchard J. 2008. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 24:408-415.
    • (2008) Trends Genet , vol.24 , pp. 408-415
    • Gilad, Y.1    Rifkin, S.2    Pritchard, J.3
  • 7
    • 3142699887 scopus 로고    scopus 로고
    • Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans
    • Hahn M, Rockman M, Soranzo N, Goldstein D, Wray G. 2004. Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. Genetics. 167:867-877.
    • (2004) Genetics , vol.167 , pp. 867-877
    • Hahn, M.1    Rockman, M.2    Soranzo, N.3    Goldstein, D.4    Wray, G.5
  • 8
    • 0033911892 scopus 로고    scopus 로고
    • Detection of the signature of natural selection in humans: Evidence from the Duffy blood group locus
    • Hamblin M, Di Rienzo A. 2000. Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus. Am J Hum Genet. 66:1669-1679.
    • (2000) Am J Hum Genet , vol.66 , pp. 1669-1679
    • Hamblin, M.1    Di Rienzo, A.2
  • 9
    • 34548346860 scopus 로고    scopus 로고
    • Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution
    • Haygood R, Fedrigo O, Hanson B, Yokoyama K, Wray G. 2007. Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution. Nat Genet. 39:1140-1144.
    • (2007) Nat Genet , vol.39 , pp. 1140-1144
    • Haygood, R.1    Fedrigo, O.2    Hanson, B.3    Yokoyama, K.4    Wray, G.5
  • 10
    • 34247855863 scopus 로고    scopus 로고
    • The locus of evolution: Evo devo and the genetics of adaptation
    • Hoekstra H, Coyne J. 2007. The locus of evolution: evo devo and the genetics of adaptation. Evolution. 61:995-1016.
    • (2007) Evolution , vol.61 , pp. 995-1016
    • Hoekstra, H.1    Coyne, J.2
  • 11
    • 0028215929 scopus 로고
    • Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster
    • Hudson R, Bailey K, Skarecky D, Kwiatowski J, Ayala F. 1994. Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster. Genetics. 136:1329-1340.
    • (1994) Genetics , vol.136 , pp. 1329-1340
    • Hudson, R.1    Bailey, K.2    Skarecky, D.3    Kwiatowski, J.4    Ayala, F.5
  • 12
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • International HapMap Consortium
    • International HapMap Consortium. 2007. A second generation human haplotype map of over 3.1 million SNPs. Nature. 449:851-861.
    • (2007) Nature , vol.449 , pp. 851-861
  • 13
    • 38549131376 scopus 로고    scopus 로고
    • Karolchik D, Kuhn R, Baertsch R, et al. (25 co-authors). 2008. The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res. 36:D773-D779.
    • Karolchik D, Kuhn R, Baertsch R, et al. (25 co-authors). 2008. The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res. 36:D773-D779.
  • 14
    • 34748819978 scopus 로고    scopus 로고
    • Measurement of the human allele frequency spectrum demonstrates greater genetic drift in east Asians than in Europeans
    • Keinan A, Mullikin J, Patterson N, Reich D. 2007. Measurement of the human allele frequency spectrum demonstrates greater genetic drift in east Asians than in Europeans. Nat Genet. 39:1251-1255.
    • (2007) Nat Genet , vol.39 , pp. 1251-1255
    • Keinan, A.1    Mullikin, J.2    Patterson, N.3    Reich, D.4
  • 15
    • 0036226603 scopus 로고    scopus 로고
    • BLAT - the BLAST-like alignment tool
    • Kent W. 2002. BLAT - the BLAST-like alignment tool. Genome Res. 12:656-664.
    • (2002) Genome Res , vol.12 , pp. 656-664
    • Kent, W.1
  • 16
    • 34848901059 scopus 로고    scopus 로고
    • Adaptive evolution of conserved noncoding elements in mammals
    • Kim S, Pritchard J. 2007. Adaptive evolution of conserved noncoding elements in mammals. PLoS Genet. 3:1572-1586.
    • (2007) PLoS Genet , vol.3 , pp. 1572-1586
    • Kim, S.1    Pritchard, J.2
  • 17
    • 29144485743 scopus 로고
    • (25 co-authors). 2005. SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans
    • Lamason R, Mohideen M, Mest J, et al. (25 co-authors). 2005. SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science. 310:1782-1786.
    • (1782) Science , vol.310
    • Lamason, R.1    Mohideen, M.2    Mest, J.3
  • 19
    • 34047103363 scopus 로고    scopus 로고
    • Miyamoto Y, Mabuchi A, Shi D, et al. (16 co-authors). 2007. A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat Genet. 39:529-533.
    • Miyamoto Y, Mabuchi A, Shi D, et al. (16 co-authors). 2007. A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat Genet. 39:529-533.
  • 21
    • 84868869451 scopus 로고    scopus 로고
    • Online mendelian inheritance in man, omim (tm). McKusick-Nathans Institute of Genetic Medicine
    • Bethesda MD, National Library of Medicine. Available from
    • OMIM. 2008. Online mendelian inheritance in man, omim (tm). McKusick-Nathans Institute of Genetic Medicine. Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information. Bethesda (MD): National Library of Medicine. Available from: http://www.ncbi.nlm.nih.gov/ omim/.
    • (2008) Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information
  • 22
  • 23
    • 33750428182 scopus 로고    scopus 로고
    • Forces shaping the fastest evolving regions in the human genome. PLoS Genet
    • 13 co-authors
    • Pollard K, Salama S, King B, et al. (13 co-authors). 2006. Forces shaping the fastest evolving regions in the human genome. PLoS Genet. 2:e168.
    • (2006) , vol.2
    • Pollard, K.1    Salama, S.2    King, B.3
  • 24
    • 33750737061 scopus 로고    scopus 로고
    • Accelerated evolution of conserved noncoding sequences in humans
    • Prabhakar S, Noonan J, Pbo S, Rubin E. 2006. Accelerated evolution of conserved noncoding sequences in humans. Science. 314:786.
    • (2006) Science , vol.314 , pp. 786
    • Prabhakar, S.1    Noonan, J.2    Pbo, S.3    Rubin, E.4
  • 25
    • 0034977045 scopus 로고    scopus 로고
    • Linkage disequilibrium in humans: Models and data
    • Pritchard J, Przeworski M. 2001. Linkage disequilibrium in humans: models and data. Am J Hum Genet. 69:1-14.
    • (2001) Am J Hum Genet , vol.69 , pp. 1-14
    • Pritchard, J.1    Przeworski, M.2
  • 26
    • 33846057724 scopus 로고    scopus 로고
    • NCBI reference sequences (RefSeq): A curated non-redundant sequence database of genomes, transcripts and proteins
    • Pruitt K, Tatusova T, Maglott D. 2007. NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 35:D61-D65.
    • (2007) Nucleic Acids Res , vol.35
    • Pruitt, K.1    Tatusova, T.2    Maglott, D.3
  • 27
  • 28
    • 0037167852 scopus 로고    scopus 로고
    • Sabeti P, Reich D, Higgins J, et al. (17 co-authors). 2002. Detecting recent positive selection in the human genome from haplotype structure. Nature. 419:832-837.
    • Sabeti P, Reich D, Higgins J, et al. (17 co-authors). 2002. Detecting recent positive selection in the human genome from haplotype structure. Nature. 419:832-837.
  • 29
    • 85152974001 scopus 로고    scopus 로고
    • Sabeti P, Varilly P, Fry B, et al. (13 co-authors). 2007. Genomewide detection and characterization of positive selection in human populations. Nature. 449:913-918.
    • Sabeti P, Varilly P, Fry B, et al. (13 co-authors). 2007. Genomewide detection and characterization of positive selection in human populations. Nature. 449:913-918.
  • 30
    • 38649121127 scopus 로고    scopus 로고
    • Sanna S, Jackson A, Nagaraja R, et al. (38 co-authors). 2008. Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet. 40:198-203.
    • Sanna S, Jackson A, Nagaraja R, et al. (38 co-authors). 2008. Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet. 40:198-203.
  • 31
    • 34547622688 scopus 로고    scopus 로고
    • Imputation-based analysis of association studies: Candidate regions and quantitative traits
    • Servin B, Stephens M. 2007. Imputation-based analysis of association studies: candidate regions and quantitative traits. PLoS Genet. 3:e114.
    • (2007) PLoS Genet , vol.3
    • Servin, B.1    Stephens, M.2
  • 32
    • 13844270527 scopus 로고    scopus 로고
    • Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation
    • Stephens M, Scheet P. 2005. Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet. 76:449-462.
    • (2005) Am J Hum Genet , vol.76 , pp. 449-462
    • Stephens, M.1    Scheet, P.2
  • 33
    • 33846978695 scopus 로고    scopus 로고
    • Stranger B, Forrest M, Dunning M, et al. (17 co-authors). 2007. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science. 315:848-853.
    • Stranger B, Forrest M, Dunning M, et al. (17 co-authors). 2007. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science. 315:848-853.
  • 34
    • 34548738566 scopus 로고    scopus 로고
    • Stranger B, Nica A, Forrest M, et al. (14 co-authors). 2007. Population genomics of human gene expression. Nat Genet. 39:1217-1224.
    • Stranger B, Nica A, Forrest M, et al. (14 co-authors). 2007. Population genomics of human gene expression. Nat Genet. 39:1217-1224.
  • 35
    • 34547110828 scopus 로고    scopus 로고
    • A new approach for using genome scans to detect recent positive selection in the human genome
    • Tang K, Thornton K, Stoneking M. 2007. A new approach for using genome scans to detect recent positive selection in the human genome. PLoS Biol. 5:e171.
    • (2007) PLoS Biol , vol.5
    • Tang, K.1    Thornton, K.2    Stoneking, M.3
  • 36
    • 33744815615 scopus 로고    scopus 로고
    • How reliable are empirical genomic scans for selective sweeps?
    • Teshima K, Coop G, Przeworski M. 2006. How reliable are empirical genomic scans for selective sweeps? Genome Research. 16:702-712.
    • (2006) Genome Research , vol.16 , pp. 702-712
    • Teshima, K.1    Coop, G.2    Przeworski, M.3
  • 37
    • 33845900450 scopus 로고    scopus 로고
    • Tishkoff S, Reed F, Ranciaro A, et al. (19 co-authors). 2007. Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet. 39:31-40.
    • Tishkoff S, Reed F, Ranciaro A, et al. (19 co-authors). 2007. Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet. 39:31-40.
  • 38
    • 55449112450 scopus 로고    scopus 로고
    • Veyrieras J, Kudaravalli S, Dermitzakis E, Gilad Y, Stephens M, Pritchard J. 2008. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 4(10):e1000214.
    • Veyrieras J, Kudaravalli S, Dermitzakis E, Gilad Y, Stephens M, Pritchard J. 2008. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 4(10):e1000214.
  • 40
    • 30444460720 scopus 로고    scopus 로고
    • Global landscape of recent inferred Darwinian selection for Homo sapiens
    • Wang E, Kodama G, Baldi P, Moyzis R. 2006. Global landscape of recent inferred Darwinian selection for Homo sapiens. Proc Natl Acad Sci USA. 103:135-140.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 135-140
    • Wang, E.1    Kodama, G.2    Baldi, P.3    Moyzis, R.4
  • 41
    • 33847057226 scopus 로고    scopus 로고
    • The evolutionary significance of cis-regulatory mutations
    • Wray G. 2007. The evolutionary significance of cis-regulatory mutations. Nat Rev Genet. 8:206-216.
    • (2007) Nat Rev Genet , vol.8 , pp. 206-216
    • Wray, G.1


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