-
1
-
-
34247562576
-
Syndrome-causing mutations of the BLM gene in persons in the Bloom's Syndrome Registry
-
German J., Sanz M.M., Ciocci S., Ye T.Z., Ellis N.A. Syndrome-causing mutations of the BLM gene in persons in the Bloom's Syndrome Registry. Hum. Mutat. 2007, 28:743-753.
-
(2007)
Hum. Mutat.
, vol.28
, pp. 743-753
-
-
German, J.1
Sanz, M.M.2
Ciocci, S.3
Ye, T.Z.4
Ellis, N.A.5
-
2
-
-
0016290545
-
Bloom's syndrome. III. Analysis of the chromosome aberration characteristic of this disorder
-
German J., Crippa L.P., Bloom D. Bloom's syndrome. III. Analysis of the chromosome aberration characteristic of this disorder. Chromosoma 1974, 48:361-366.
-
(1974)
Chromosoma
, vol.48
, pp. 361-366
-
-
German, J.1
Crippa, L.P.2
Bloom, D.3
-
3
-
-
0346351375
-
A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
-
Chaganti R.S., Schonberg S., German J. A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 1974, 71:4508-4512.
-
(1974)
Proc. Natl. Acad. Sci. U. S. A.
, vol.71
, pp. 4508-4512
-
-
Chaganti, R.S.1
Schonberg, S.2
German, J.3
-
4
-
-
3142546346
-
A retarded rate of DNA chain growth in Bloom's syndrome
-
Hand R., German J. A retarded rate of DNA chain growth in Bloom's syndrome. Proc. Natl. Acad. Sci. U. S. A. 1975, 72:758-762.
-
(1975)
Proc. Natl. Acad. Sci. U. S. A.
, vol.72
, pp. 758-762
-
-
Hand, R.1
German, J.2
-
5
-
-
0025302748
-
An abnormal profile of DNA replication intermediates in Bloom's syndrome
-
Lonn U., Lonn S., Nylen U., Winblad G., German J. An abnormal profile of DNA replication intermediates in Bloom's syndrome. Cancer Res. 1990, 50:3141-3145.
-
(1990)
Cancer Res.
, vol.50
, pp. 3141-3145
-
-
Lonn, U.1
Lonn, S.2
Nylen, U.3
Winblad, G.4
German, J.5
-
6
-
-
65449187038
-
Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair
-
Bernstein K.A., Shor E., Sunjevaric I., Fumasoni M., Burgess R.C., Foiani M., Branzei D., Rothstein R. Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair. EMBO J. 2009, 28:915-925.
-
(2009)
EMBO J.
, vol.28
, pp. 915-925
-
-
Bernstein, K.A.1
Shor, E.2
Sunjevaric, I.3
Fumasoni, M.4
Burgess, R.C.5
Foiani, M.6
Branzei, D.7
Rothstein, R.8
-
8
-
-
84902187810
-
Human RecQ helicases in DNA repair, recombination, and replication
-
Croteau D.L., Popuri V., Opresko P.L., Bohr V.A. Human RecQ helicases in DNA repair, recombination, and replication. Annu. Rev. Biochem. 2014, 519-552.
-
(2014)
Annu. Rev. Biochem.
, pp. 519-552
-
-
Croteau, D.L.1
Popuri, V.2
Opresko, P.L.3
Bohr, V.A.4
-
9
-
-
36849029846
-
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase
-
Bugreev D., Yu X., Egelman E., Mazin A. Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev. 2007, 21:3085-3094.
-
(2007)
Genes Dev.
, vol.21
, pp. 3085-3094
-
-
Bugreev, D.1
Yu, X.2
Egelman, E.3
Mazin, A.4
-
10
-
-
0034727684
-
Binding and melting of D-loops by the bloom syndrome helicase
-
Van Brabant A.J., Ye T., Sanz M., German I.J., Ellis N.A., Holloman W.K. Binding and melting of D-loops by the bloom syndrome helicase. Biochemistry (Mosc.) 2000, 39:14617-14625.
-
(2000)
Biochemistry (Mosc.)
, vol.39
, pp. 14617-14625
-
-
Van Brabant, A.J.1
Ye, T.2
Sanz, M.3
German, I.J.4
Ellis, N.A.5
Holloman, W.K.6
-
11
-
-
73949087271
-
SUMO modification regulates BLM and RAD51 interaction at damaged replication forks
-
Ouyang K.J., Woo L.L., Zhu J., Huo D., Matunis M.J., Ellis N.A. SUMO modification regulates BLM and RAD51 interaction at damaged replication forks. PLoS Biol. 2009, 7:e1000252.
-
(2009)
PLoS Biol.
, vol.7
-
-
Ouyang, K.J.1
Woo, L.L.2
Zhu, J.3
Huo, D.4
Matunis, M.J.5
Ellis, N.A.6
-
12
-
-
0034612333
-
The Bloom's syndrome gene product promotes branch migration of holliday junctions
-
Karow J., Constantinou A., Li J., West S., Hickson I. The Bloom's syndrome gene product promotes branch migration of holliday junctions. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:6504-6508.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 6504-6508
-
-
Karow, J.1
Constantinou, A.2
Li, J.3
West, S.4
Hickson, I.5
-
13
-
-
1642458364
-
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest
-
Davies S.L., North P.S., Dart A., Lakin N.D., Hickson I.D. Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Mol. Cell Biol. 2004, 24:1279-1291.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 1279-1291
-
-
Davies, S.L.1
North, P.S.2
Dart, A.3
Lakin, N.D.4
Hickson, I.D.5
-
14
-
-
18544372261
-
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM
-
Beamish H., Kedar P., Kaneko H., Chen P., Fukao T., Peng C., Beresten S., Gueven N., Purdie D., Lees-Miller S., Ellis N., Kondo N., Lavin M.F. Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM. J. Biol. Chem. 2002, 277:30515-30523.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30515-30523
-
-
Beamish, H.1
Kedar, P.2
Kaneko, H.3
Chen, P.4
Fukao, T.5
Peng, C.6
Beresten, S.7
Gueven, N.8
Purdie, D.9
Lees-Miller, S.10
Ellis, N.11
Kondo, N.12
Lavin, M.F.13
-
15
-
-
0034619757
-
ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation
-
Ababou M., Dutertre S., Lecluse Y., Onclercq R., Chatton B., Amor-Gueret M. ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation. Oncogene 2000, 19:5955-5963.
-
(2000)
Oncogene
, vol.19
, pp. 5955-5963
-
-
Ababou, M.1
Dutertre, S.2
Lecluse, Y.3
Onclercq, R.4
Chatton, B.5
Amor-Gueret, M.6
-
16
-
-
4544235194
-
Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest
-
Sengupta S., Robles A.I., Linke S.P., Sinogeeva N.I., Zhang R., Pedeux R., Ward I.M., Celeste A., Nussenzweig A., Chen J., Halazonetis T.D., Harris C.C. Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest. J. Cell Biol. 2004, 166:801-813.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 801-813
-
-
Sengupta, S.1
Robles, A.I.2
Linke, S.P.3
Sinogeeva, N.I.4
Zhang, R.5
Pedeux, R.6
Ward, I.M.7
Celeste, A.8
Nussenzweig, A.9
Chen, J.10
Halazonetis, T.D.11
Harris, C.C.12
-
17
-
-
77957131183
-
Chk1-dependent constitutive phosphorylation of BLM helicase at serine 646 decreases after DNA damage
-
Kaur S., Modi P., Srivastava V., Mudgal R., Tikoo S., Arora P., Mohanty D., Sengupta S. Chk1-dependent constitutive phosphorylation of BLM helicase at serine 646 decreases after DNA damage. Mol. Cancer Res. 2010, 8:1234-1247.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1234-1247
-
-
Kaur, S.1
Modi, P.2
Srivastava, V.3
Mudgal, R.4
Tikoo, S.5
Arora, P.6
Mohanty, D.7
Sengupta, S.8
-
18
-
-
84867304481
-
The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures
-
Barefield C., Karlseder J. The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures. Nucleic Acids Res. 2012, 40:7358-7367.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 7358-7367
-
-
Barefield, C.1
Karlseder, J.2
-
19
-
-
77952583242
-
An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs
-
Chen C.F., Brill S.J. An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs. EMBO J. 2010, 29:1713-1725.
-
(2010)
EMBO J.
, vol.29
, pp. 1713-1725
-
-
Chen, C.F.1
Brill, S.J.2
-
20
-
-
0034737641
-
The Bloom's syndrome gene product interacts with topoisomerase III
-
Wu L., Davies S.L., North P.S., Goulaouic H., Riou J.F., Turley H., Gatter K.C., Hickson I.D. The Bloom's syndrome gene product interacts with topoisomerase III. J. Biol. Chem. 2000, 275:9636-9644.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9636-9644
-
-
Wu, L.1
Davies, S.L.2
North, P.S.3
Goulaouic, H.4
Riou, J.F.5
Turley, H.6
Gatter, K.C.7
Hickson, I.D.8
-
21
-
-
0028033989
-
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase
-
Gangloff S., McDonald J., Bendixen C., Arthur L., Rothstein R. The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell Biol. 1994, 14:8391-8398.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 8391-8398
-
-
Gangloff, S.1
McDonald, J.2
Bendixen, C.3
Arthur, L.4
Rothstein, R.5
-
22
-
-
21244434850
-
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex
-
Chang M., Bellaoui M., Zhang C., Desai R., Morozov P., Delgado-Cruzata L., Rothstein R., Freyer G., Boone C., Brown G. RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J. 2005, 24:2024-2033.
-
(2005)
EMBO J.
, vol.24
, pp. 2024-2033
-
-
Chang, M.1
Bellaoui, M.2
Zhang, C.3
Desai, R.4
Morozov, P.5
Delgado-Cruzata, L.6
Rothstein, R.7
Freyer, G.8
Boone, C.9
Brown, G.10
-
23
-
-
33645242115
-
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
-
Wu L., Bachrati C.Z., Ou J., Xu C., Yin J., Chang M., Wang W., Li L., Brown G.W., Hickson I.D. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:4068-4073.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4068-4073
-
-
Wu, L.1
Bachrati, C.Z.2
Ou, J.3
Xu, C.4
Yin, J.5
Chang, M.6
Wang, W.7
Li, L.8
Brown, G.W.9
Hickson, I.D.10
-
24
-
-
33744927719
-
A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75
-
Raynard S., Bussen W., Sung P. A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75. J. Biol. Chem. 2006, 281:13861-13864.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13861-13864
-
-
Raynard, S.1
Bussen, W.2
Sung, P.3
-
25
-
-
0035377356
-
Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51
-
Wu L., Davies S., Levitt N., Hickson I. Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J. Biol. Chem. 2001, 276:19375-19381.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19375-19381
-
-
Wu, L.1
Davies, S.2
Levitt, N.3
Hickson, I.4
-
26
-
-
84890241687
-
TopBP1 controls BLM protein level to maintain genome stability
-
Wang J., Chen J., Gong Z. TopBP1 controls BLM protein level to maintain genome stability. Mol. Cell 2013, 52:667-678.
-
(2013)
Mol. Cell
, vol.52
, pp. 667-678
-
-
Wang, J.1
Chen, J.2
Gong, Z.3
-
27
-
-
0032760273
-
Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase
-
Gharibyan V., Youssoufian H. Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase. Mol. Carcinog. 1999, 26:261-273.
-
(1999)
Mol. Carcinog.
, vol.26
, pp. 261-273
-
-
Gharibyan, V.1
Youssoufian, H.2
-
28
-
-
0034713244
-
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
-
Dutertre S., Ababou M., Onclercq R., Delic J., Chatton B., Jaulin C., Amor-Gueret M. Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase. Oncogene 2000, 19:2731-2738.
-
(2000)
Oncogene
, vol.19
, pp. 2731-2738
-
-
Dutertre, S.1
Ababou, M.2
Onclercq, R.3
Delic, J.4
Chatton, B.5
Jaulin, C.6
Amor-Gueret, M.7
-
29
-
-
0037238008
-
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta
-
Itoh M., Kim C.H., Palardy G., Oda T., Jiang Y.J., Maust D., Yeo S.Y., Lorick K., Wright G.J., Ariza-McNaughton L., Weissman A.M., Lewis J., Chandrasekharappa S.C., Chitnis A.B. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 2003, 4:67-82.
-
(2003)
Dev. Cell
, vol.4
, pp. 67-82
-
-
Itoh, M.1
Kim, C.H.2
Palardy, G.3
Oda, T.4
Jiang, Y.J.5
Maust, D.6
Yeo, S.Y.7
Lorick, K.8
Wright, G.J.9
Ariza-McNaughton, L.10
Weissman, A.M.11
Lewis, J.12
Chandrasekharappa, S.C.13
Chitnis, A.B.14
-
30
-
-
84879562441
-
The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein
-
Kwon D.Y., Dimitriadi M., Terzic B., Cable C., Hart A.C., Chitnis A., Fischbeck K.H., Burnett B.G. The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein. Mol. Biol. Cell 2013, 24:1863-1871.
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 1863-1871
-
-
Kwon, D.Y.1
Dimitriadi, M.2
Terzic, B.3
Cable, C.4
Hart, A.C.5
Chitnis, A.6
Fischbeck, K.H.7
Burnett, B.G.8
-
31
-
-
79955009072
-
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
-
Jakobsen L., Vanselow K., Skogs M., Toyoda Y., Lundberg E., Poser I., Falkenby L.G., Bennetzen M., Westendorf J., Nigg E.A., Uhlen M., Hyman A.A., Andersen J.S. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J. 2011, 30:1520-1535.
-
(2011)
EMBO J.
, vol.30
, pp. 1520-1535
-
-
Jakobsen, L.1
Vanselow, K.2
Skogs, M.3
Toyoda, Y.4
Lundberg, E.5
Poser, I.6
Falkenby, L.G.7
Bennetzen, M.8
Westendorf, J.9
Nigg, E.A.10
Uhlen, M.11
Hyman, A.A.12
Andersen, J.S.13
-
32
-
-
1642511792
-
TopBP1 localises to centrosomes in mitosis and to chromosome cores in meiosis
-
Reini K., Uitto L., Perera D., Moens P.B., Freire R., Syvaoja J.E. TopBP1 localises to centrosomes in mitosis and to chromosome cores in meiosis. Chromosoma 2004, 112:323-330.
-
(2004)
Chromosoma
, vol.112
, pp. 323-330
-
-
Reini, K.1
Uitto, L.2
Perera, D.3
Moens, P.B.4
Freire, R.5
Syvaoja, J.E.6
-
33
-
-
0242456024
-
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response
-
Makiniemi M., Hillukkala T., Tuusa J., Reini K., Vaara M., Huang D., Pospiech H., Majuri I., Westerling T., Makela T.P., Syvaoja J.E. BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J. Biol. Chem. 2001, 276:30399-30406.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30399-30406
-
-
Makiniemi, M.1
Hillukkala, T.2
Tuusa, J.3
Reini, K.4
Vaara, M.5
Huang, D.6
Pospiech, H.7
Majuri, I.8
Westerling, T.9
Makela, T.P.10
Syvaoja, J.E.11
-
34
-
-
0038746602
-
Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint
-
Yamane K., Chen J., Kinsella T.J. Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint. Cancer Res. 2003, 63:3049-3053.
-
(2003)
Cancer Res.
, vol.63
, pp. 3049-3053
-
-
Yamane, K.1
Chen, J.2
Kinsella, T.J.3
-
35
-
-
0037979238
-
PML colocalizes with and stabilizes the DNA damage response protein TopBP1
-
Xu Z.X., Timanova-Atanasova A., Zhao R.X., Chang K.S. PML colocalizes with and stabilizes the DNA damage response protein TopBP1. Mol. Cell Biol. 2003, 23:4247-4256.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 4247-4256
-
-
Xu, Z.X.1
Timanova-Atanasova, A.2
Zhao, R.X.3
Chang, K.S.4
-
36
-
-
77649165394
-
Maintaining genome stability at the replication fork
-
Branzei D., Foiani M. Maintaining genome stability at the replication fork. Nat. Rev. Mol. Cell Biol. 2010, 11:208-219.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 208-219
-
-
Branzei, D.1
Foiani, M.2
-
37
-
-
26444467122
-
Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage
-
Rao V.A., Fan A.M., Meng L., Doe C.F., North P.S., Hickson I.D., Pommier Y. Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage. Mol. Cell. Biol. 2005, 25:8925-8937.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8925-8937
-
-
Rao, V.A.1
Fan, A.M.2
Meng, L.3
Doe, C.F.4
North, P.S.5
Hickson, I.D.6
Pommier, Y.7
-
38
-
-
38849137795
-
Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination
-
Tripathi V., Kaur S., Sengupta S. Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination. Carcinogenesis 2008, 29:52-61.
-
(2008)
Carcinogenesis
, vol.29
, pp. 52-61
-
-
Tripathi, V.1
Kaur, S.2
Sengupta, S.3
-
39
-
-
68249126215
-
Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response
-
Stracker T.H., Usui T., Petrini J.H. Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response. DNA Repair (Amst.) 2009, 8:1047-1054.
-
(2009)
DNA Repair (Amst.)
, vol.8
, pp. 1047-1054
-
-
Stracker, T.H.1
Usui, T.2
Petrini, J.H.3
-
40
-
-
0033598931
-
A role for PML and the nuclear body in genomic stability
-
Zhong S., Hu P., Ye T., Stan R., Ellis N., Pandolfi P. A role for PML and the nuclear body in genomic stability. Oncogene 1999, 18:7941-7947.
-
(1999)
Oncogene
, vol.18
, pp. 7941-7947
-
-
Zhong, S.1
Hu, P.2
Ye, T.3
Stan, R.4
Ellis, N.5
Pandolfi, P.6
-
41
-
-
0029097216
-
Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein
-
Dyck J.A., Warrell R.P., Evans R.M., Miller W.H. Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein. Blood 1995, 86:862-867.
-
(1995)
Blood
, vol.86
, pp. 862-867
-
-
Dyck, J.A.1
Warrell, R.P.2
Evans, R.M.3
Miller, W.H.4
-
42
-
-
0028293945
-
The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion
-
Koken M.H., Puvion-Dutilleul F., Guillemin M.C., Viron A., Linares-Cruz G., Stuurman N., de Jong L., Szostecki C., Calvo F., Chomienne C., et al. The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion. EMBO J. 1994, 13:1073-1083.
-
(1994)
EMBO J.
, vol.13
, pp. 1073-1083
-
-
Koken, M.H.1
Puvion-Dutilleul, F.2
Guillemin, M.C.3
Viron, A.4
Linares-Cruz, G.5
Stuurman, N.6
de Jong, L.7
Szostecki, C.8
Calvo, F.9
Chomienne, C.10
-
43
-
-
0028158682
-
Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells
-
Weis K., Rambaud S., Lavau C., Jansen J., Carvalho T., Carmo-Fonseca M., Lamond A., Dejean A. Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells. Cell 1994, 76:345-356.
-
(1994)
Cell
, vol.76
, pp. 345-356
-
-
Weis, K.1
Rambaud, S.2
Lavau, C.3
Jansen, J.4
Carvalho, T.5
Carmo-Fonseca, M.6
Lamond, A.7
Dejean, A.8
-
44
-
-
84865074686
-
The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies
-
de The H., Le Bras M., Lallemand-Breitenbach V. The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies. J. Cell Biol. 2012, 198:11-21.
-
(2012)
J. Cell Biol.
, vol.198
, pp. 11-21
-
-
de The, H.1
Le Bras, M.2
Lallemand-Breitenbach, V.3
-
45
-
-
4644351274
-
PML nuclear bodies: dynamic sensors of DNA damage and cellular stress
-
Dellaire G., Bazett-Jones D.P. PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays 2004, 26:963-977.
-
(2004)
Bioessays
, vol.26
, pp. 963-977
-
-
Dellaire, G.1
Bazett-Jones, D.P.2
-
46
-
-
0034730633
-
NBS1 TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres
-
Wu G., Lee W.H., Chen P.L. NBS1 TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. J. Biol. Chem. 2000, 275:30618-30622.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30618-30622
-
-
Wu, G.1
Lee, W.H.2
Chen, P.L.3
-
47
-
-
0034749425
-
DNA damage-dependent nuclear dynamics of the Mre11 complex
-
Mirzoeva O.K., Petrini J.H. DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol. Cell Biol. 2001, 21:281-288.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 281-288
-
-
Mirzoeva, O.K.1
Petrini, J.H.2
-
48
-
-
0033199695
-
Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
-
Yeager T.R., Neumann A.A., Englezou A., Huschtscha L.I., Noble J.R., Reddel R.R. Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res. 1999, 59:4175-4179.
-
(1999)
Cancer Res.
, vol.59
, pp. 4175-4179
-
-
Yeager, T.R.1
Neumann, A.A.2
Englezou, A.3
Huschtscha, L.I.4
Noble, J.R.5
Reddel, R.R.6
-
49
-
-
0035363706
-
Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability
-
Hu P., Beresten S.F., van Brabant A.J., Ye T.Z., Pandolfi P.P., Johnson F.B., Guarente L., Ellis N.A. Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability. Hum. Mol. Genet. 2001, 10:1287-1298.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1287-1298
-
-
Hu, P.1
Beresten, S.F.2
van Brabant, A.J.3
Ye, T.Z.4
Pandolfi, P.P.5
Johnson, F.B.6
Guarente, L.7
Ellis, N.A.8
-
50
-
-
0037416149
-
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
-
Sengupta S., Linke S.P., Pedeux R., Yang Q., Farnsworth J., Garfield S.H., Valerie K., Shay J.W., Ellis N.A., Wasylyk B., Harris C.C. BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 2003, 22:1210-1222.
-
(2003)
EMBO J.
, vol.22
, pp. 1210-1222
-
-
Sengupta, S.1
Linke, S.P.2
Pedeux, R.3
Yang, Q.4
Farnsworth, J.5
Garfield, S.H.6
Valerie, K.7
Shay, J.W.8
Ellis, N.A.9
Wasylyk, B.10
Harris, C.C.11
-
51
-
-
0034669124
-
Regulation of p53 activity in nuclear bodies by a specific PML isoform
-
Fogal V., Gostissa M., Sandy P., Zacchi P., Sternsdorf T., Jensen K., Pandolfi P.P., Will H., Schneider C., Del Sal G. Regulation of p53 activity in nuclear bodies by a specific PML isoform. EMBO J. 2000, 19:6185-6195.
-
(2000)
EMBO J.
, vol.19
, pp. 6185-6195
-
-
Fogal, V.1
Gostissa, M.2
Sandy, P.3
Zacchi, P.4
Sternsdorf, T.5
Jensen, K.6
Pandolfi, P.P.7
Will, H.8
Schneider, C.9
Del Sal, G.10
-
52
-
-
0034306019
-
The function of PML in p53-dependent apoptosis
-
Guo A., Salomoni P., Luo J., Shih A., Zhong S., Gu W., Pandolfi P.P. The function of PML in p53-dependent apoptosis. Nat. Cell Biol. 2000, 2:730-736.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 730-736
-
-
Guo, A.1
Salomoni, P.2
Luo, J.3
Shih, A.4
Zhong, S.5
Gu, W.6
Pandolfi, P.P.7
-
53
-
-
34447129654
-
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
-
Potts P.R., Yu H. The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat. Struct. Mol. Biol. 2007, 14:581-590.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 581-590
-
-
Potts, P.R.1
Yu, H.2
-
54
-
-
81355161213
-
De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation
-
Chung I., Leonhardt H., Rippe K. De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation. J. Cell Sci. 2011, 124:3603-3618.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 3603-3618
-
-
Chung, I.1
Leonhardt, H.2
Rippe, K.3
-
55
-
-
19744378341
-
Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification
-
Eladad S., Ye T.Z., Hu P., Leversha M., Beresten S., Matunis M.J., Ellis N.A. Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification. Hum. Mol. Genet. 2005, 14:1351-1365.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1351-1365
-
-
Eladad, S.1
Ye, T.Z.2
Hu, P.3
Leversha, M.4
Beresten, S.5
Matunis, M.J.6
Ellis, N.A.7
-
56
-
-
57649198342
-
Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification
-
Zhu J., Zhu S., Guzzo C.M., Ellis N.A., Sung K.S., Choi C.Y., Matunis M.J. Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification. J. Biol. Chem. 2008, 283:29405-29415.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29405-29415
-
-
Zhu, J.1
Zhu, S.2
Guzzo, C.M.3
Ellis, N.A.4
Sung, K.S.5
Choi, C.Y.6
Matunis, M.J.7
-
57
-
-
84879463452
-
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination
-
Tikoo S., Madhavan V., Hussain M., Miller E.S., Arora P., Zlatanou A., Modi P., Townsend K., Stewart G.S., Sengupta S. Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination. EMBO J. 2013, 32:1778-1792.
-
(2013)
EMBO J.
, vol.32
, pp. 1778-1792
-
-
Tikoo, S.1
Madhavan, V.2
Hussain, M.3
Miller, E.S.4
Arora, P.5
Zlatanou, A.6
Modi, P.7
Townsend, K.8
Stewart, G.S.9
Sengupta, S.10
-
58
-
-
0037155218
-
Dephosphorylation and subcellular compartment change of the mitotic Bloom's syndrome DNA helicase in response to ionizing radiation
-
Dutertre S., Sekhri R., Tintignac L.A., Onclercq-Delic R., Chatton B., Jaulin C., Amor-Gueret M. Dephosphorylation and subcellular compartment change of the mitotic Bloom's syndrome DNA helicase in response to ionizing radiation. J. Biol. Chem. 2002, 277:6280-6286.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6280-6286
-
-
Dutertre, S.1
Sekhri, R.2
Tintignac, L.A.3
Onclercq-Delic, R.4
Chatton, B.5
Jaulin, C.6
Amor-Gueret, M.7
-
59
-
-
33747868423
-
The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase
-
Bayart E., Dutertre S., Jaulin C., Guo R.B., Xi X.G., Amor-Gueret M. The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase. Cell Cycle 2006, 5:1681-1686.
-
(2006)
Cell Cycle
, vol.5
, pp. 1681-1686
-
-
Bayart, E.1
Dutertre, S.2
Jaulin, C.3
Guo, R.B.4
Xi, X.G.5
Amor-Gueret, M.6
-
60
-
-
34547192058
-
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
-
Chan K.L., North P.S., Hickson I.D. BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J. 2007, 26:3397-3409.
-
(2007)
EMBO J.
, vol.26
, pp. 3397-3409
-
-
Chan, K.L.1
North, P.S.2
Hickson, I.D.3
-
61
-
-
81955161162
-
New insights into the formation and resolution of ultra-fine anaphase bridges
-
Chan K.L., Hickson I.D. New insights into the formation and resolution of ultra-fine anaphase bridges. Semin. Cell Dev. Biol. 2011, 22:906-912.
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 906-912
-
-
Chan, K.L.1
Hickson, I.D.2
-
62
-
-
33746841515
-
MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability
-
Leng M., Chan D.W., Luo H., Zhu C., Qin J., Wang Y. MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:11485-11490.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 11485-11490
-
-
Leng, M.1
Chan, D.W.2
Luo, H.3
Zhu, C.4
Qin, J.5
Wang, Y.6
-
63
-
-
43049162175
-
RecQ helicases: guardian angels of the DNA replication fork
-
Bachrati C.Z., Hickson I.D. RecQ helicases: guardian angels of the DNA replication fork. Chromosoma 2008, 117:219-233.
-
(2008)
Chromosoma
, vol.117
, pp. 219-233
-
-
Bachrati, C.Z.1
Hickson, I.D.2
-
64
-
-
17144395509
-
ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation
-
Davalos A.R., Kaminker P., Hansen R.K., Campisi J. ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation. Cell Cycle 2004, 3:1579-1586.
-
(2004)
Cell Cycle
, vol.3
, pp. 1579-1586
-
-
Davalos, A.R.1
Kaminker, P.2
Hansen, R.K.3
Campisi, J.4
-
65
-
-
0346993508
-
Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells
-
Rassool F.V., North P.S., Mufti G.J., Hickson I.D. Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells. Oncogene 2003, 22:8749-8757.
-
(2003)
Oncogene
, vol.22
, pp. 8749-8757
-
-
Rassool, F.V.1
North, P.S.2
Mufti, G.J.3
Hickson, I.D.4
-
66
-
-
0141864666
-
Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks
-
Davalos A.R., Campisi J. Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks. J. Cell Biol. 2003, 162:1197-1209.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 1197-1209
-
-
Davalos, A.R.1
Campisi, J.2
-
67
-
-
84886034846
-
BLM SUMOylation regulates ssDNA accumulation at stalled replication forks
-
Ouyang K.J., Yagle M.K., Matunis M.J., Ellis N.A. BLM SUMOylation regulates ssDNA accumulation at stalled replication forks. Front. Genet. 2013, 4:167.
-
(2013)
Front. Genet.
, vol.4
, pp. 167
-
-
Ouyang, K.J.1
Yagle, M.K.2
Matunis, M.J.3
Ellis, N.A.4
-
69
-
-
55949105327
-
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
-
Nimonkar A.V., Ozsoy A.Z., Genschel J., Modrich P., Kowalczykowski S.C. Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:16906-16911.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 16906-16911
-
-
Nimonkar, A.V.1
Ozsoy, A.Z.2
Genschel, J.3
Modrich, P.4
Kowalczykowski, S.C.5
-
70
-
-
53649090109
-
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
-
Gravel S., Chapman J.R., Magill C., Jackson S.P. DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev. 2008, 22:2767-2772.
-
(2008)
Genes Dev.
, vol.22
, pp. 2767-2772
-
-
Gravel, S.1
Chapman, J.R.2
Magill, C.3
Jackson, S.P.4
-
72
-
-
53349162987
-
CDK targets Sae2 to control DNA-end resection and homologous recombination
-
Huertas P., Cortes-Ledesma F., Sartori A.A., Aguilera A., Jackson S.P. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 2008, 455:689-693.
-
(2008)
Nature
, vol.455
, pp. 689-693
-
-
Huertas, P.1
Cortes-Ledesma, F.2
Sartori, A.A.3
Aguilera, A.4
Jackson, S.P.5
-
73
-
-
84903628980
-
Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection
-
Makharashvili N., Tubbs A.T., Yang S.H., Wang H., Barton O., Zhou Y., Deshpande R.A., Lee J.H., Lobrich M., Sleckman B.P., Wu X., Paull T.T. Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection. Mol. Cell 2014, 1022-1033.
-
(2014)
Mol. Cell
, pp. 1022-1033
-
-
Makharashvili, N.1
Tubbs, A.T.2
Yang, S.H.3
Wang, H.4
Barton, O.5
Zhou, Y.6
Deshpande, R.A.7
Lee, J.H.8
Lobrich, M.9
Sleckman, B.P.10
Wu, X.11
Paull, T.T.12
-
74
-
-
84885838052
-
A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining
-
Grabarz A., Guirouilh-Barbat J., Barascu A., Pennarun G., Genet D., Rass E., Germann S.M., Bertrand P., Hickson I.D., Lopez B.S. A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining. Cell Rep. 2013, 5:21-28.
-
(2013)
Cell Rep.
, vol.5
, pp. 21-28
-
-
Grabarz, A.1
Guirouilh-Barbat, J.2
Barascu, A.3
Pennarun, G.4
Genet, D.5
Rass, E.6
Germann, S.M.7
Bertrand, P.8
Hickson, I.D.9
Lopez, B.S.10
-
75
-
-
84876527317
-
RIF1 counteracts BRCA1-mediated end resection during DNA repair
-
Feng L., Fong K.W., Wang J., Wang W., Chen J. RIF1 counteracts BRCA1-mediated end resection during DNA repair. J. Biol. Chem. 2013, 288:11135-11143.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 11135-11143
-
-
Feng, L.1
Fong, K.W.2
Wang, J.3
Wang, W.4
Chen, J.5
-
76
-
-
34347388428
-
BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination
-
Tripathi V., Nagarjuna T., Sengupta S. BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination. J. Cell Biol. 2007, 178:9-14.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 9-14
-
-
Tripathi, V.1
Nagarjuna, T.2
Sengupta, S.3
-
77
-
-
33646843592
-
Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase
-
Bachrati C., Borts R., Hickson I. Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase. Nucleic Acids Res. 2006, 34:2269-2279.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 2269-2279
-
-
Bachrati, C.1
Borts, R.2
Hickson, I.3
-
78
-
-
49249114958
-
RAP80 responds to DNA damage induced by both ionizing radiation and UV irradiation and is phosphorylated at Ser 205
-
Yan J., Yang X.P., Kim Y.S., Jetten A.M. RAP80 responds to DNA damage induced by both ionizing radiation and UV irradiation and is phosphorylated at Ser 205. Cancer Res. 2008, 68:4269-4276.
-
(2008)
Cancer Res.
, vol.68
, pp. 4269-4276
-
-
Yan, J.1
Yang, X.P.2
Kim, Y.S.3
Jetten, A.M.4
-
79
-
-
77649180958
-
Telomeres: protecting chromosomes against genome instability
-
O'Sullivan R.J., Karlseder J. Telomeres: protecting chromosomes against genome instability. Nat. Rev. Mol. Cell Biol. 2010, 11:171-181.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 171-181
-
-
O'Sullivan, R.J.1
Karlseder, J.2
-
80
-
-
0029162563
-
Telomere elongation in immortal human cells without detectable telomerase activity
-
Bryan T.M., Englezou A., Gupta J., Bacchetti S., Reddel R.R. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 1995, 14:4240-4248.
-
(1995)
EMBO J.
, vol.14
, pp. 4240-4248
-
-
Bryan, T.M.1
Englezou, A.2
Gupta, J.3
Bacchetti, S.4
Reddel, R.R.5
-
81
-
-
4544367827
-
Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2
-
Lillard-Wetherell K., Machwe A., Langland G.T., Combs K.A., Behbehani G.K., Schonberg S.A., German J., Turchi J.J., Orren D.K., Groden J. Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2. Hum. Mol. Genet. 2004, 13:1919-1932.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1919-1932
-
-
Lillard-Wetherell, K.1
Machwe, A.2
Langland, G.T.3
Combs, K.A.4
Behbehani, G.K.5
Schonberg, S.A.6
German, J.7
Turchi, J.J.8
Orren, D.K.9
Groden, J.10
-
82
-
-
0036899106
-
The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis
-
Stavropoulos D.J., Bradshaw P.S., Li X., Pasic I., Truong K., Ikura M., Ungrin M., Meyn M.S. The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis. Hum. Mol. Genet. 2002, 11:3135-3144.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 3135-3144
-
-
Stavropoulos, D.J.1
Bradshaw, P.S.2
Li, X.3
Pasic, I.4
Truong, K.5
Ikura, M.6
Ungrin, M.7
Meyn, M.S.8
-
83
-
-
0037175018
-
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
-
Opresko P.L., von Kobbe C., Laine J.P., Harrigan J., Hickson I.D., Bohr V.A. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J. Biol. Chem. 2002, 277:41110-41119.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41110-41119
-
-
Opresko, P.L.1
von Kobbe, C.2
Laine, J.P.3
Harrigan, J.4
Hickson, I.D.5
Bohr, V.A.6
-
84
-
-
84863824454
-
PML body meets telomere: the beginning of an ALTernate ending?
-
Chung I., Osterwald S., Deeg K.I., Rippe K. PML body meets telomere: the beginning of an ALTernate ending?. Nucleus 2012, 3:263-275.
-
(2012)
Nucleus
, vol.3
, pp. 263-275
-
-
Chung, I.1
Osterwald, S.2
Deeg, K.I.3
Rippe, K.4
-
85
-
-
0035969102
-
SUMO: of branched proteins and nuclear bodies
-
Seeler J.S., Dejean A. SUMO: of branched proteins and nuclear bodies. Oncogene 2001, 20:7243-7249.
-
(2001)
Oncogene
, vol.20
, pp. 7243-7249
-
-
Seeler, J.S.1
Dejean, A.2
-
86
-
-
70349158606
-
Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination
-
Draskovic I., Arnoult N., Steiner V., Bacchetti S., Lomonte P., Londono-Vallejo A. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:15726-15731.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 15726-15731
-
-
Draskovic, I.1
Arnoult, N.2
Steiner, V.3
Bacchetti, S.4
Lomonte, P.5
Londono-Vallejo, A.6
-
87
-
-
77951133257
-
Alternative lengthening of telomeres: models, mechanisms and implications
-
Cesare A.J., Reddel R.R. Alternative lengthening of telomeres: models, mechanisms and implications. Nat. Rev. Genet. 2010, 11:319-330.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 319-330
-
-
Cesare, A.J.1
Reddel, R.R.2
-
88
-
-
84893757512
-
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1
-
O'Sullivan R.J., Arnoult N., Lackner D.H., Oganesian L., Haggblom C., Corpet A., Almouzni G., Karlseder J. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat. Struct. Mol. Biol. 2014, 21:167-174.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 167-174
-
-
O'Sullivan, R.J.1
Arnoult, N.2
Lackner, D.H.3
Oganesian, L.4
Haggblom, C.5
Corpet, A.6
Almouzni, G.7
Karlseder, J.8
-
89
-
-
33750437743
-
Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks
-
Branzei D., Sollier J., Liberi G., Zhao X., Maeda D., Seki M., Enomoto T., Ohta K., Foiani M. Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell 2006, 127:509-522.
-
(2006)
Cell
, vol.127
, pp. 509-522
-
-
Branzei, D.1
Sollier, J.2
Liberi, G.3
Zhao, X.4
Maeda, D.5
Seki, M.6
Enomoto, T.7
Ohta, K.8
Foiani, M.9
-
90
-
-
77449147101
-
Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast
-
Lu C.Y., Tsai C.H., Brill S.J., Teng S.C. Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast. Nucleic Acids Res. 2009, 488-498.
-
(2009)
Nucleic Acids Res.
, pp. 488-498
-
-
Lu, C.Y.1
Tsai, C.H.2
Brill, S.J.3
Teng, S.C.4
-
91
-
-
0033513079
-
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae
-
Teng S.C., Zakian V.A. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol. Cell Biol. 1999, 19:8083-8093.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8083-8093
-
-
Teng, S.C.1
Zakian, V.A.2
-
92
-
-
61649085240
-
Sumoylation of RecQ helicase controls the fate of dysfunctional telomeres
-
Rog O., Miller K.M., Ferreira M.G., Cooper J.P. Sumoylation of RecQ helicase controls the fate of dysfunctional telomeres. Mol. Cell 2009, 33:559-569.
-
(2009)
Mol. Cell
, vol.33
, pp. 559-569
-
-
Rog, O.1
Miller, K.M.2
Ferreira, M.G.3
Cooper, J.P.4
-
93
-
-
0033957793
-
The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
-
Frei C., Gasser S.M. The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev. 2000, 14:81-96.
-
(2000)
Genes Dev.
, vol.14
, pp. 81-96
-
-
Frei, C.1
Gasser, S.M.2
-
94
-
-
84865715286
-
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress
-
Tkach J.M., Yimit A., Lee A.Y., Riffle M., Costanzo M., Jaschob D., Hendry J.A., Ou J., Moffat J., Boone C., Davis T.N., Nislow C., Brown G.W. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat. Cell Biol. 2012, 14:966-976.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 966-976
-
-
Tkach, J.M.1
Yimit, A.2
Lee, A.Y.3
Riffle, M.4
Costanzo, M.5
Jaschob, D.6
Hendry, J.A.7
Ou, J.8
Moffat, J.9
Boone, C.10
Davis, T.N.11
Nislow, C.12
Brown, G.W.13
-
95
-
-
84866378510
-
An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks
-
Hegnauer A.M., Hustedt N., Shimada K., Pike B.L., Vogel M., Amsler P., Rubin S.M., van Leeuwen F., Guenole A., van Attikum H., Thoma N.H., Gasser S.M. An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks. EMBO J. 2012, 31:3768-3783.
-
(2012)
EMBO J.
, vol.31
, pp. 3768-3783
-
-
Hegnauer, A.M.1
Hustedt, N.2
Shimada, K.3
Pike, B.L.4
Vogel, M.5
Amsler, P.6
Rubin, S.M.7
van Leeuwen, F.8
Guenole, A.9
van Attikum, H.10
Thoma, N.H.11
Gasser, S.M.12
-
96
-
-
84869840130
-
Non-Bloom syndrome-associated partial and total loss-of-function variants of BLM helicase
-
Mirzaei H., Schmidt K.H. Non-Bloom syndrome-associated partial and total loss-of-function variants of BLM helicase. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:19357-19362.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 19357-19362
-
-
Mirzaei, H.1
Schmidt, K.H.2
-
97
-
-
84866932831
-
Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles
-
Thompson E.R., Doyle M.A., Ryland G.L., Rowley S.M., Choong D.Y., Tothill R.W., Thorne H., Barnes D.R., Li J., Ellul J., Philip G.K., Antill Y.C., James P.A., Trainer A.H., Mitchell G., Campbell I.G. Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles. PLoS Genet. 2012, 8:e1002894.
-
(2012)
PLoS Genet.
, vol.8
-
-
Thompson, E.R.1
Doyle, M.A.2
Ryland, G.L.3
Rowley, S.M.4
Choong, D.Y.5
Tothill, R.W.6
Thorne, H.7
Barnes, D.R.8
Li, J.9
Ellul, J.10
Philip, G.K.11
Antill, Y.C.12
James, P.A.13
Trainer, A.H.14
Mitchell, G.15
Campbell, I.G.16
-
98
-
-
0037144601
-
Enhanced tumor formation in mice heterozygous for Blm mutation
-
Goss K.H., Risinger M.A., Kordich J.J., Sanz M.M., Straughen J.E., Slovek L.E., Capobianco A.J., German J., Boivin G.P., Groden J. Enhanced tumor formation in mice heterozygous for Blm mutation. Science 2002, 297:2051-2053.
-
(2002)
Science
, vol.297
, pp. 2051-2053
-
-
Goss, K.H.1
Risinger, M.A.2
Kordich, J.J.3
Sanz, M.M.4
Straughen, J.E.5
Slovek, L.E.6
Capobianco, A.J.7
German, J.8
Boivin, G.P.9
Groden, J.10
-
99
-
-
18544386262
-
BLM heterozygosity and the risk of colorectal cancer
-
Gruber S.B., Ellis N.A., Scott K.K., Almog R., Kolachana P., Bonner J.D., Kirchhoff T., Tomsho L.P., Nafa K., Pierce H., Low M., Satagopan J., Rennert H., Huang H., Greenson J.K., Groden J., Rapaport B., Shia J., Johnson S., Gregersen P.K., Harris C.C., Boyd J., Rennert G., Offit K. BLM heterozygosity and the risk of colorectal cancer. Science 2002, 297:2013.
-
(2002)
Science
, vol.297
, pp. 2013
-
-
Gruber, S.B.1
Ellis, N.A.2
Scott, K.K.3
Almog, R.4
Kolachana, P.5
Bonner, J.D.6
Kirchhoff, T.7
Tomsho, L.P.8
Nafa, K.9
Pierce, H.10
Low, M.11
Satagopan, J.12
Rennert, H.13
Huang, H.14
Greenson, J.K.15
Groden, J.16
Rapaport, B.17
Shia, J.18
Johnson, S.19
Gregersen, P.K.20
Harris, C.C.21
Boyd, J.22
Rennert, G.23
Offit, K.24
more..
-
100
-
-
84859757946
-
Modulation of telomeres in alternative lengthening of telomeres type I like human cells by the expression of werner protein and telomerase
-
Siddiqa A., Cavazos D., Chavez J., Long L., Marciniak R.A. Modulation of telomeres in alternative lengthening of telomeres type I like human cells by the expression of werner protein and telomerase. J. Oncol. 2012, 2012:806382.
-
(2012)
J. Oncol.
, vol.2012
, pp. 806382
-
-
Siddiqa, A.1
Cavazos, D.2
Chavez, J.3
Long, L.4
Marciniak, R.A.5
-
101
-
-
19944428332
-
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas
-
Henson J.D., Hannay J.A., McCarthy S.W., Royds J.A., Yeager T.R., Robinson R.A., Wharton S.B., Jellinek D.A., Arbuckle S.M., Yoo J., Robinson B.G., Learoyd D.L., Stalley P.D., Bonar S.F., Yu D., Pollock R.E., Reddel R.R. A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clin. Cancer Res. 2005, 11:217-225.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 217-225
-
-
Henson, J.D.1
Hannay, J.A.2
McCarthy, S.W.3
Royds, J.A.4
Yeager, T.R.5
Robinson, R.A.6
Wharton, S.B.7
Jellinek, D.A.8
Arbuckle, S.M.9
Yoo, J.10
Robinson, B.G.11
Learoyd, D.L.12
Stalley, P.D.13
Bonar, S.F.14
Yu, D.15
Pollock, R.E.16
Reddel, R.R.17
-
102
-
-
1942533449
-
Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically
-
Montgomery E., Argani P., Hicks J.L., DeMarzo A.M., Meeker A.K. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. Am. J. Pathol. 2004, 164:1523-1529.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 1523-1529
-
-
Montgomery, E.1
Argani, P.2
Hicks, J.L.3
DeMarzo, A.M.4
Meeker, A.K.5
-
103
-
-
84864619205
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
-
Lovejoy C.A., Li W., Reisenweber S., Thongthip S., Bruno J., de Lange T., De S., Petrini J.H., Sung P.A., Jasin M., Rosenbluh J., Zwang Y., Weir B.A., Hatton C., Ivanova E., Macconaill L., Hanna M., Hahn W.C., Lue N.F., Reddel R.R., Jiao Y., Kinzler K., Vogelstein B., Papadopoulos N., Meeker A.K. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet. 2012, 8:e1002772.
-
(2012)
PLoS Genet.
, vol.8
-
-
Lovejoy, C.A.1
Li, W.2
Reisenweber, S.3
Thongthip, S.4
Bruno, J.5
de Lange, T.6
De, S.7
Petrini, J.H.8
Sung, P.A.9
Jasin, M.10
Rosenbluh, J.11
Zwang, Y.12
Weir, B.A.13
Hatton, C.14
Ivanova, E.15
Macconaill, L.16
Hanna, M.17
Hahn, W.C.18
Lue, N.F.19
Reddel, R.R.20
Jiao, Y.21
Kinzler, K.22
Vogelstein, B.23
Papadopoulos, N.24
Meeker, A.K.25
more..
-
104
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan T.M., Englezou A., Dalla-Pozza L., Dunham M.A., Reddel R.R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 1997, 3:1271-1274.
-
(1997)
Nat. Med.
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
106
-
-
84872966436
-
A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells
-
Nguyen G.H., Dexheimer T.S., Rosenthal A.S., Chu W.K., Singh D.K., Mosedale G., Bachrati C.Z., Schultz L., Sakurai M., Savitsky P., Abu M., McHugh P.J., Bohr V.A., Harris C.C., Jadhav A., Gileadi O., Maloney D.J., Simeonov A., Hickson I.D. A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells. Chem. Biol. 2013, 20:55-62.
-
(2013)
Chem. Biol.
, vol.20
, pp. 55-62
-
-
Nguyen, G.H.1
Dexheimer, T.S.2
Rosenthal, A.S.3
Chu, W.K.4
Singh, D.K.5
Mosedale, G.6
Bachrati, C.Z.7
Schultz, L.8
Sakurai, M.9
Savitsky, P.10
Abu, M.11
McHugh, P.J.12
Bohr, V.A.13
Harris, C.C.14
Jadhav, A.15
Gileadi, O.16
Maloney, D.J.17
Simeonov, A.18
Hickson, I.D.19
|