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Volumn 29, Issue 1, 2008, Pages 52-61

Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; BINDING PROTEIN; BLOOM HELICASE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE RAD3; HELICASE; PROTEIN P53 BINDING PROTEIN; RAD51 PROTEIN; RECOMBINANT PROTEIN; THREONINE; UNCLASSIFIED DRUG;

EID: 38849137795     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm238     Document Type: Article
Times cited : (36)

References (38)
  • 1
    • 33847271255 scopus 로고    scopus 로고
    • Links between DNA double strand break repair and breast cancor: Accumulating evidence from both familial and nonfamilial cases
    • Ralhan,R. et al. (2007) Links between DNA double strand break repair and breast cancor: Accumulating evidence from both familial and nonfamilial cases. Cancer Lett., 248, 1-17.
    • (2007) Cancer Lett , vol.248 , pp. 1-17
    • Ralhan, R.1
  • 2
    • 0033514993 scopus 로고    scopus 로고
    • Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
    • Raderschall,E. et al. (1999) Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc. Natl. Acad. Sci. USA, 96, 1921-1926.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1921-1926
    • Raderschall, E.1
  • 3
    • 0032526320 scopus 로고    scopus 로고
    • Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian, cells to ionizing radiation
    • Vispe,S. et al. (1998) Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian, cells to ionizing radiation. Nucleic Acids Res., 26, 2859-2864.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2859-2864
    • Vispe, S.1
  • 4
    • 13944266820 scopus 로고    scopus 로고
    • The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
    • Sorensen,C.S. et al. (2005) The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat. Cell Biol., 7, 195-201.
    • (2005) Nat. Cell Biol , vol.7 , pp. 195-201
    • Sorensen, C.S.1
  • 5
    • 0038519801 scopus 로고    scopus 로고
    • p53 Interacts with hRAD51 and hRAD54, and directly modulates homologous recombination
    • Linke,S.P. et al. (2003) p53 Interacts with hRAD51 and hRAD54, and directly modulates homologous recombination. Cancer Res., 63 2596-2605.
    • (2003) Cancer Res , vol.63 , pp. 2596-2605
    • Linke, S.P.1
  • 6
    • 34347388428 scopus 로고    scopus 로고
    • BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination
    • Tripathi,V et al. (2007) BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination. J. Cell Biol., 178, 9-14.
    • (2007) J. Cell Biol , vol.178 , pp. 9-14
    • Tripathi, V.1
  • 7
    • 34248202517 scopus 로고    scopus 로고
    • Tying the loose ends together in DNA double strand break repair with 53BP1
    • Adams,M.M. et al. (2006) Tying the loose ends together in DNA double strand break repair with 53BP1. Cell Div., 1, 19.
    • (2006) Cell Div , vol.1 , pp. 19
    • Adams, M.M.1
  • 8
    • 0037772381 scopus 로고    scopus 로고
    • Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability
    • Morales,J.C. et al. (2003) Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J. Biol. Chem. 278, 14971-14977.
    • (2003) J. Biol. Chem , vol.278 , pp. 14971-14977
    • Morales, J.C.1
  • 9
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone, H2AX
    • Ward,I.M. et al. (2003) Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone, H2AX. J. Biol. Chem., 278, 19579-19582.
    • (2003) J. Biol. Chem , vol.278 , pp. 19579-19582
    • Ward, I.M.1
  • 10
    • 0036903037 scopus 로고    scopus 로고
    • DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
    • Fernandez-Capetillo,O. et al. (2002) DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat. Cell Biol., 4, 993-997.
    • (2002) Nat. Cell Biol , vol.4 , pp. 993-997
    • Fernandez-Capetillo, O.1
  • 11
    • 4544235194 scopus 로고    scopus 로고
    • Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest
    • Sengupta,S. et al. (2004) Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest. J. Cell Biol., 166, 801-813.
    • (2004) J. Cell Biol , vol.166 , pp. 801-813
    • Sengupta, S.1
  • 12
    • 21744432851 scopus 로고    scopus 로고
    • Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination
    • Restle,A. et al. (2005) Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination. Oncogene, 24, 4380-4387.
    • (2005) Oncogene , vol.24 , pp. 4380-4387
    • Restle, A.1
  • 13
    • 0037416149 scopus 로고    scopus 로고
    • BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
    • Sengupta,S. et al. (2003) BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J., 22, 1210-1222.
    • (2003) EMBO J , vol.22 , pp. 1210-1222
    • Sengupta, S.1
  • 14
    • 33747868423 scopus 로고    scopus 로고
    • The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase
    • Bayart,E. et al. (2006) The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase. Cell Cycle, 5, 1681-1686.
    • (2006) Cell Cycle , vol.5 , pp. 1681-1686
    • Bayart, E.1
  • 15
    • 33746841515 scopus 로고    scopus 로고
    • MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability
    • Leng,M. et al. (2006) MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability. Proc. Natl Acad. Sci. USA, 103, 11485-11490.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 11485-11490
    • Leng, M.1
  • 16
    • 1642458364 scopus 로고    scopus 로고
    • Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest
    • Davies,S.L. et al. (2004) Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Mol. Cell. Biol., 24, 1279-1291.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 1279-1291
    • Davies, S.L.1
  • 17
    • 18544372261 scopus 로고    scopus 로고
    • Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM
    • Beamish,H. et al. (2002) Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM. J. Biol. Chem., 217, 30515-30523.
    • (2002) J. Biol. Chem , vol.217 , pp. 30515-30523
    • Beamish, H.1
  • 18
    • 29144486147 scopus 로고    scopus 로고
    • Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations
    • Cobb,J.A. et al. (2005) Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes Dev., 19, 3055-3069.
    • (2005) Genes Dev , vol.19 , pp. 3055-3069
    • Cobb, J.A.1
  • 19
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • Wu,L. et al. (2003) The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature, 426, 870-874.
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1
  • 20
    • 0035377356 scopus 로고    scopus 로고
    • Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51
    • Wu,L. et al. (2001) Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J. Mol. Chem., 276, 19375-19381.
    • (2001) J. Mol. Chem , vol.276 , pp. 19375-19381
    • Wu, L.1
  • 21
    • 0037069326 scopus 로고    scopus 로고
    • Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
    • Zhao,H. et al. (2002) Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc. Natl Acad. Sci. USA, 99, 14795-14800.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 14795-14800
    • Zhao, H.1
  • 22
    • 0037468169 scopus 로고    scopus 로고
    • MDC1 is required for the intra-S-phase DNA damage checkpoint
    • Goldberg,M. et al. (2003) MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature, 421, 952-956.
    • (2003) Nature , vol.421 , pp. 952-956
    • Goldberg, M.1
  • 23
    • 4043133287 scopus 로고    scopus 로고
    • ATR couples FANCD2 monoubiquitination to the DNA-damage response
    • Andreassen,P.R. et al. (2004) ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev., 18 1958-1963.
    • (2004) Genes Dev , vol.18 , pp. 1958-1963
    • Andreassen, P.R.1
  • 24
    • 0034805573 scopus 로고    scopus 로고
    • A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines
    • Slebos,R.J. et al. (2001) A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines. Biochem. Biophys. Res. Common., 281, 212-219.
    • (2001) Biochem. Biophys. Res. Common , vol.281 , pp. 212-219
    • Slebos, R.J.1
  • 25
    • 0034739853 scopus 로고    scopus 로고
    • p53 bindiit protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz,L.B. et al. (2000) p53 bindiit protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol., 151, 1381-1390.
    • (2000) J. Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1
  • 26
    • 29244456155 scopus 로고    scopus 로고
    • The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53HP1 DNA binding activity
    • Boisvert,F.M. et al. (2005) The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53HP1 DNA binding activity. Cell Cycle, 4, 1834-1841.
    • (2005) Cell Cycle , vol.4 , pp. 1834-1841
    • Boisvert, F.M.1
  • 27
    • 29244445502 scopus 로고    scopus 로고
    • 53BP1 oligomerization is independent of its methylation by PRMT1
    • Adams,M.M. et al. (2005) 53BP1 oligomerization is independent of its methylation by PRMT1. Cell Cycle, 4, 1854-1861.
    • (2005) Cell Cycle , vol.4 , pp. 1854-1861
    • Adams, M.M.1
  • 28
    • 33846015507 scopus 로고    scopus 로고
    • The tandem BRC7 domain of 53BP1 is not required for its repair function
    • Ward,I. et al. (2006) The tandem BRC7 domain of 53BP1 is not required for its repair function. J. Biol. Chem., 281, 38472-38477.
    • (2006) J. Biol. Chem , vol.281 , pp. 38472-38477
    • Ward, I.1
  • 29
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • Bartek,J. et al. (2003) Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell, 3, 421-429.
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1
  • 30
    • 9244252580 scopus 로고    scopus 로고
    • Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
    • Huyen,Y. et al. (2004) Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature, 432, 406-411.
    • (2004) Nature , vol.432 , pp. 406-411
    • Huyen, Y.1
  • 31
    • 33845666681 scopus 로고    scopus 로고
    • Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
    • Botuyan,M.V. et al. (2006) Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell, 127, 1361-1373.
    • (2006) Cell , vol.127 , pp. 1361-1373
    • Botuyan, M.V.1
  • 32
    • 33745137149 scopus 로고    scopus 로고
    • Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
    • Du,L.L. et al. (2006) Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Genes Dev., 20, 1583-1596.
    • (2006) Genes Dev , vol.20 , pp. 1583-1596
    • Du, L.L.1
  • 33
    • 33344464960 scopus 로고    scopus 로고
    • ATM regulates ATR chromatin loading in response to DNA double-strand breaks
    • Cuadrado,M. et al. (2006) ATM regulates ATR chromatin loading in response to DNA double-strand breaks. J. Exp. Med., 203, 297-303.
    • (2006) J. Exp. Med , vol.203 , pp. 297-303
    • Cuadrado, M.1
  • 34
    • 30344463835 scopus 로고    scopus 로고
    • ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
    • Jazayeri,A. et al. (2006) ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol., 8, 37-45.
    • (2006) Nat. Cell Biol , vol.8 , pp. 37-45
    • Jazayeri, A.1
  • 35
    • 33845715977 scopus 로고    scopus 로고
    • ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
    • Stiff,T. et al. (2006) ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. EMBO J., 25, 5775-5782.
    • (2006) EMBO J , vol.25 , pp. 5775-5782
    • Stiff, T.1
  • 36
    • 26444467122 scopus 로고    scopus 로고
    • Phosphorylatioa of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage
    • Rao,V.A. et al. (2005) Phosphorylatioa of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage. Mol. Cell. Biol., 25, 8925-8937.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 8925-8937
    • Rao, V.A.1
  • 37
    • 17144395509 scopus 로고    scopus 로고
    • ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation
    • Davalos,A.R. et al. (2004) ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation. Cell Cycle, 3, 1579-1586.
    • (2004) Cell Cycle , vol.3 , pp. 1579-1586
    • Davalos, A.R.1
  • 38
    • 0037673943 scopus 로고    scopus 로고
    • The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments
    • Veaute,X. et al. (2003) The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. Nature, 423, 309-312.
    • (2003) Nature , vol.423 , pp. 309-312
    • Veaute, X.1


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