Effect of tacrine-3-caffeic acid, a novel multifunctional anti-alzheimer's dimer, against oxidative-stress-induced cell death in HT22 hippocampal neurons: Involvement of Nrf2/HO-1 pathway

CNS Neuroscience and Therapeutics

Volumn 20, Issue 9, 2014, Pages 840-850

  Chao, Xiao Juan ^a,f   Chen, Zi Wei ^a   Liu, An Min ^a   He, Xi Xin ^b   Wang, Shao Gui ^a   Wang, Yu Ting ^a   Liu, Pei Qing ^a   Ramassamy, Charles ^c   Mak, Shing Hung ^d   Cui, Wei ^d   Kong, Ah Ng ^e   Yu, Zhi Ling ^f   Han, Yi Fan ^d   Pi, Rong Biao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^c INRS INSTITUT ARMAND FRAPPIER   (Canada)

^d HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^e RUTGERS UNIVERSITY   (United States)

^f HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Cell death; HO 1; Nrf2; Oxidative stress; T3CA

Indexed keywords

CAFFEIC ACID DERIVATIVE; DIMER; GLUTAMIC ACID; HEME OXYGENASE 1; MESSENGER RNA; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; TACRINE 3 CAFFEIC ACID; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; CAFFEIC ACID; CYTOSKELETON PROTEIN; KEAP1 PROTEIN, MOUSE; NOOTROPIC AGENT; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; TACRINE;

ANIMAL EXPERIMENT; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CELL DISRUPTION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; IMMUNOFLUORESCENCE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; REPORTER GENE; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; GENETIC TRANSFECTION; HUMAN; METABOLISM; NERVE CELL; SIGNAL TRANSDUCTION; TRANSFORMED CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CAFFEIC ACIDS; CELL DEATH; CELL LINE, TRANSFORMED; CYTOSKELETAL PROTEINS; GLUTAMIC ACID; HEME OXYGENASE-1; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; NEURONS; NF-E2-RELATED FACTOR 2; NOOTROPIC AGENTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TACRINE; TRANSFECTION;

EID: 84906239766     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12286     Document Type: Article

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