-
1
-
-
80053132801
-
Clostridium difficile infection in humans and animals, differences and similarities
-
PMID:21530110
-
Keessen EC, Gaastra W, Lipman LJ. Clostridium difficile infection in humans and animals, differences and similarities. Vet Microbiol 2011; 153:205-17; PMID:21530110; http://dx.doi.org/10.1016/j.vetmic.2011.03.020
-
(2011)
Vet Microbiol
, vol.153
, pp. 205-217
-
-
Keessen, E.C.1
Gaastra, W.2
Lipman, L.J.3
-
2
-
-
0029742398
-
The distribution of Clostridium difficile in the environment of South Wales
-
PMID:8683549
-
al Saif N, Brazier JS. The distribution of Clostridium difficile in the environment of South Wales. J Med Microbiol 1996; 45:133-7; PMID:8683549; http://dx.doi.org/10.1099/00222615-45-2-133
-
(1996)
J Med Microbiol
, vol.45
, pp. 133-137
-
-
Al Saif, N.1
Brazier, J.S.2
-
3
-
-
77956056345
-
The occurrence and high diversity of Clostridium difficile genotypes in rivers
-
PMID:20541023
-
Zidaric V, Beigot S, Lapajne S, Rupnik M. The occurrence and high diversity of Clostridium difficile genotypes in rivers. Anaerobe 2010; 16:371-5; PMID:20541023; http://dx.doi.org/10.1016/j.anaerobe.2010.06.001
-
(2010)
Anaerobe
, vol.16
, pp. 371-375
-
-
Zidaric, V.1
Beigot, S.2
Lapajne, S.3
Rupnik, M.4
-
4
-
-
0000795948
-
Intestinal flora in new-born infants: With a description of anew pathogenic anaerobe, Bacillus difficilis
-
Hall IC, O'Toole E. Intestinal flora in new-born infants: with a description of anew pathogenic anaerobe, Bacillus difficilis. Am J Dis Child 1935; 49:390-402; http://dx.doi.org/10.1001/archpedi.1935.01970020105010
-
(1935)
Am J Dis Child
, vol.49
, pp. 390-402
-
-
Hall, I.C.1
O'Toole, E.2
-
5
-
-
0018075343
-
Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis
-
PMID:700321
-
Bartlett JGMN, Moon N, Chang TW, Taylor N, Onderdonk AB. Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis. Gastroenterology 1978; 75:778-82; PMID:700321
-
(1978)
Gastroenterology
, vol.75
, pp. 778-782
-
-
Bartlett, J.G.M.N.1
Moon, N.2
Chang, T.W.3
Taylor, N.4
Onderdonk, A.B.5
-
6
-
-
39749111479
-
Measures to control and prevent Clostridium difficile infection
-
PMID:18177221
-
Gerding DNMC, Muto CA, Owens RC Jr. Measures to control and prevent Clostridium difficile infection. Clin Infect Dis 2008; 46(Suppl 1):S43-9; PMID:18177221; http://dx.doi.org/10.1086/521861
-
(2008)
Clin Infect Dis
, vol.46
, Issue.SUPPL. 1
-
-
Gerding, D.N.M.C.1
Muto, C.A.2
Owens Jr., R.C.3
-
7
-
-
42449133334
-
Infection control measures to limit the spread of Clostridium difficile
-
European C difficile-Infection Control Group; European Centre for Disease Prevention and Control (ECDC) PMID:18412710
-
Vonberg RPKE, Kuijper EJ, Wilcox MH, Barbut F, Tüll P, Gastmeier P, van den Broek PJ, Colville A, Coignard B, Daha T, et al.; European C difficile-Infection Control Group; European Centre for Disease Prevention and Control (ECDC). Infection control measures to limit the spread of Clostridium difficile. Clin Microbiol Infect 2008; 14(Suppl 5):2-20; PMID:18412710; http://dx.doi.org/10.1111/j.1469-0691.2008.01992.x
-
(2008)
Clin Microbiol Infect
, vol.14
, Issue.SUPPL. 5
, pp. 2-20
-
-
Vonberg, R.P.K.E.1
Kuijper, E.J.2
Wilcox, M.H.3
Barbut, F.4
Tüll, P.5
Gastmeier, P.6
Van Den Broek, P.J.7
Colville, A.8
Coignard, B.9
Daha, T.10
-
8
-
-
41549142775
-
Bile salts and glycine as cogerminants for Clostridium difficile spores
-
PMID:18245298
-
Sorg JASA, Sonenshein AL. Bile salts and glycine as cogerminants for Clostridium difficile spores. J Bacteriol 2008; 190:2505-12; PMID:18245298; http://dx.doi.org/10.1128/JB.01765-07
-
(2008)
J Bacteriol
, vol.190
, pp. 2505-2512
-
-
Sorg, J.A.S.A.1
Sonenshein, A.L.2
-
9
-
-
84878518519
-
Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection
-
PMID: 23675301
-
Francis MB, Allen CA, Shrestha R, Sorg JA. Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection. PLoS Pathog 2013; 9:e1003356; PMID: 23675301; http://dx.doi.org/10. 1371/journal.ppat.1003356
-
(2013)
PLoS Pathog
, vol.9
-
-
Francis, M.B.1
Allen, C.A.2
Shrestha, R.3
Sorg, J.A.4
-
10
-
-
79954578379
-
Histidine acts as a co-germinant with glycine and taurocholate for Clostridium difficile spores
-
Forthcoming; PMID:21261795
-
Wheeldon LJWT, Worthington T, Lambert PA. Histidine acts as a co-germinant with glycine and taurocholate for Clostridium difficile spores. J Appl Microbiol 2011; (Forthcoming); PMID:21261795; http://dx.doi.org/10.1111/j. 1365-2672.2011.04953.x
-
(2011)
J Appl Microbiol
-
-
Wheeldon, L.J.W.T.1
Worthington, T.2
Lambert, P.A.3
-
11
-
-
79956361126
-
Germination response of spores of the pathogenic bacterium Clostridium perfringens and Clostridium difficile to cultured human epithelial cells
-
PMID:21315167
-
Paredes-Sabja D, Sarker MR. Germination response of spores of the pathogenic bacterium Clostridium perfringens and Clostridium difficile to cultured human epithelial cells. Anaerobe 2011; 17:78-84; PMID:21315167; http://dx.doi.org/10.1016/j.anaerobe.2011.02.001
-
(2011)
Anaerobe
, vol.17
, pp. 78-84
-
-
Paredes-Sabja, D.1
Sarker, M.R.2
-
12
-
-
77957337708
-
Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid
-
PMID:20675492
-
Sorg JASA, Sonenshein AL. Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid. J Bacteriol 2010; 192:4983-90; PMID:20675492; http://dx.doi.org/10.1128/JB. 00610-10
-
(2010)
J Bacteriol
, vol.192
, pp. 4983-4990
-
-
Sorg, J.A.S.A.1
Sonenshein, A.L.2
-
13
-
-
33244467651
-
Bile salt biotransformations by human intestinal bacteria
-
PMID:16299351
-
Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. J Lipid Res 2006; 47:241-59; PMID:16299351; http://dx.doi.org/10.1194/jlr.R500013-JLR200
-
(2006)
J Lipid Res
, vol.47
, pp. 241-259
-
-
Ridlon, J.M.1
Kang, D.J.2
Hylemon, P.B.3
-
14
-
-
79956197132
-
Clostridium difficile transcriptome analysis using pig ligated loop model reveals modulation of pathways not modulated in vitro
-
PMID: 21592991
-
Scaria J, Janvilisri T, Fubini S, Gleed RD, McDonough SP, Chang YF. Clostridium difficile transcriptome analysis using pig ligated loop model reveals modulation of pathways not modulated in vitro. J Infect Dis 2011; 203:1613-20; PMID: 21592991; http://dx.doi.org/10.1093/infdis/jir112
-
(2011)
J Infect Dis
, vol.203
, pp. 1613-1620
-
-
Scaria, J.1
Janvilisri, T.2
Fubini, S.3
Gleed, R.D.4
McDonough, S.P.5
Chang, Y.F.6
-
15
-
-
77954608134
-
Transcriptional profiling of Clostridium difficile and Caco-2 cells during infection
-
PMID:20521945
-
Janvilisri T, Scaria J, Chang YF. Transcriptional profiling of Clostridium difficile and Caco-2 cells during infection. J Infect Dis 2010; 202:282-90; PMID:20521945; http://dx.doi.org/10.1086/653484
-
(2010)
J Infect Dis
, vol.202
, pp. 282-290
-
-
Janvilisri, T.1
Scaria, J.2
Chang, Y.F.3
-
16
-
-
79959365481
-
Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile
-
PMID:21531808
-
de la Riva L, Willing SE, Tate EW, Fairweather NF. Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile. J Bacteriol 2011; 193:3276-85; PMID:21531808; http://dx.doi.org/10. 1128/JB.00248-11
-
(2011)
J Bacteriol
, vol.193
, pp. 3276-3285
-
-
De La Riva, L.1
Willing, S.E.2
Tate, E.W.3
Fairweather, N.F.4
-
17
-
-
71749087319
-
Cwp84, a surface-associated cysteine protease, plays a role in the maturation of the surface layer of Clostridium difficile
-
PMID:19808679
-
Kirby JM, Ahern H, Roberts AK, Kumar V, Freeman Z, Acharya KR, Shone CC. Cwp84, a surface-associated cysteine protease, plays a role in the maturation of the surface layer of Clostridium difficile. J Biol Chem 2009; 284:34666-73; PMID:19808679; http://dx.doi.org/10.1074/jbc.M109.051177
-
(2009)
J Biol Chem
, vol.284
, pp. 34666-34673
-
-
Kirby, J.M.1
Ahern, H.2
Roberts, A.K.3
Kumar, V.4
Freeman, Z.5
Acharya, K.R.6
Shone, C.C.7
-
18
-
-
35048837277
-
Cwp84, a surface-associated protein of Clostridium difficile, is a cysteine protease with degrading activity on extracellular matrix proteins
-
PMID:17693508
-
Janoir C, Péchiné S, Grosdidier C, Collignon A. Cwp84, a surface-associated protein of Clostridium difficile, is a cysteine protease with degrading activity on extracellular matrix proteins. J Bacteriol 2007; 189:7174-80; PMID:17693508; http://dx.doi.org/10.1128/JB.00578-07
-
(2007)
J Bacteriol
, vol.189
, pp. 7174-7180
-
-
Janoir, C.1
Péchiné, S.2
Grosdidier, C.3
Collignon, A.4
-
19
-
-
17444366186
-
Clostridium difficile toxins: Mechanism of action and role in disease
-
PMID:15831824
-
Voth DE, Ballard JD. Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev 2005; 18:247-63; PMID:15831824; http://dx.doi.org/10.1128/CMR.18.2.247-263.2005
-
(2005)
Clin Microbiol Rev
, vol.18
, pp. 247-263
-
-
Voth, D.E.1
Ballard, J.D.2
-
20
-
-
0035112067
-
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins
-
PMID:11179295
-
Nusrat A, von Eichel-Streiber C, Turner JR, Verkade P, Madara JL, Parkos CA. Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins. Infect Immun 2001; 69:1329-36; PMID:11179295; http://dx.doi.org/10.1128/IAI.69.3.1329-1336. 2001
-
(2001)
Infect Immun
, vol.69
, pp. 1329-1336
-
-
Nusrat, A.1
Von Eichel-Streiber, C.2
Turner, J.R.3
Verkade, P.4
Madara, J.L.5
Parkos, C.A.6
-
21
-
-
39649088950
-
Clostridium difficile toxins: More than mere inhibitors of Rho proteins
-
PMID:18289919
-
Genth H, Dreger SC, Huelsenbeck J, Just I. Clostridium difficile toxins: more than mere inhibitors of Rho proteins. Int J Biochem Cell Biol 2008; 40:592-7; PMID:18289919; http://dx.doi.org/10.1016/j.biocel.2007.12.014
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 592-597
-
-
Genth, H.1
Dreger, S.C.2
Huelsenbeck, J.3
Just, I.4
-
22
-
-
84857790535
-
Clostridium difficile toxins: Mediators of inflammation
-
PMID:22237401
-
Shen A. Clostridium difficile toxins: mediators of inflammation. J Innate Immun 2012; 4:149-58; PMID:22237401; http://dx.doi.org/10.1159/000332946
-
(2012)
J Innate Immun
, vol.4
, pp. 149-158
-
-
Shen, A.1
-
23
-
-
0029989720
-
Enhancement of Clostridium difficile toxin production in biotin-limited conditions
-
PMID:8642571
-
Yamakawa K, Karasawa T, Ikoma S, Nakamura S. Enhancement of Clostridium difficile toxin production in biotin-limited conditions. J Med Microbiol 1996; 44:111-4; PMID:8642571; http://dx.doi.org/10.1099/00222615-44-2-111
-
(1996)
J Med Microbiol
, vol.44
, pp. 111-114
-
-
Yamakawa, K.1
Karasawa, T.2
Ikoma, S.3
Nakamura, S.4
-
24
-
-
57349199337
-
Induction of toxins in Clostridium difficile is associated with dramatic changes of its metabolism
-
PMID:18957596
-
Karlsson S, Burman LG, Akerlund T. Induction of toxins in Clostridium difficile is associated with dramatic changes of its metabolism. Microbiology 2008; 154:3430-6; PMID:18957596; http://dx.doi.org/10.1099/mic.0.2008/019778-0
-
(2008)
Microbiology
, vol.154
, pp. 3430-3436
-
-
Karlsson, S.1
Burman, L.G.2
Akerlund, T.3
-
25
-
-
0345700250
-
Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature
-
PMID:12654792
-
Karlsson S, Dupuy B, Mukherjee K, Norin E, Burman LG, Åkerlund T. Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature. Infect Immun 2003; 71:1784-93; PMID:12654792; http://dx.doi.org/10.1128/IAI.71.4.1784-1793.2003
-
(2003)
Infect Immun
, vol.71
, pp. 1784-1793
-
-
Karlsson, S.1
Dupuy, B.2
Mukherjee, K.3
Norin, E.4
Burman, L.G.5
Åkerlund, T.6
-
26
-
-
23044492161
-
Effect of antibiotic treatment on growth of and toxin production by Clostridium difficile in the cecal contents of mice
-
PMID:16048976
-
Pultz NJ, Donskey CJ. Effect of antibiotic treatment on growth of and toxin production by Clostridium difficile in the cecal contents of mice. Antimicrob Agents Chemother 2005; 49:3529-32; PMID:16048976; http://dx.doi.org/10.1128/AAC.49.8.3529-3532.2005
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3529-3532
-
-
Pultz, N.J.1
Donskey, C.J.2
-
27
-
-
1542540064
-
Effects of sub-MIC concentrations of antibiotics on growth of and toxin production by Clostridium difficile
-
PMID:14614060
-
Drummond LJ, Smith DG, Poxton IR. Effects of sub-MIC concentrations of antibiotics on growth of and toxin production by Clostridium difficile. J Med Microbiol 2003; 52:1033-8; PMID:14614060; http://dx.doi.org/10.1099/jmm.0.05387- 0
-
(2003)
J Med Microbiol
, vol.52
, pp. 1033-1038
-
-
Drummond, L.J.1
Smith, D.G.2
Poxton, I.R.3
-
28
-
-
45249121963
-
Effect of sub-MIC concentrations of metronidazole, vancomycin, clindamycin and linezolid on toxin gene transcription and production in Clostridium difficile
-
PMID:18480337
-
Gerber M, Walch C, Löffler B, Tischendorf K, Reischl U, Ackermann G. Effect of sub-MIC concentrations of metronidazole, vancomycin, clindamycin and linezolid on toxin gene transcription and production in Clostridium difficile. J Med Microbiol 2008; 57:776-83; PMID:18480337; http://dx.doi.org/10.1099/jmm.0. 47739-0
-
(2008)
J Med Microbiol
, vol.57
, pp. 776-783
-
-
Gerber, M.1
Walch, C.2
Löffler, B.3
Tischendorf, K.4
Reischl, U.5
Ackermann, G.6
-
29
-
-
84876535324
-
Effects of ciprofloxacin on the expression and production of exotoxins by Clostridium difficile
-
PMID:23429695
-
Aldape MJ, Packham AE, Nute DW, Bryant AE, Stevens DL. Effects of ciprofloxacin on the expression and production of exotoxins by Clostridium difficile. J Med Microbiol 2013; 62:741-7; PMID:23429695; http://dx.doi.org/10. 1099/jmm.0.056218-0
-
(2013)
J Med Microbiol
, vol.62
, pp. 741-747
-
-
Aldape, M.J.1
Packham, A.E.2
Nute, D.W.3
Bryant, A.E.4
Stevens, D.L.5
-
30
-
-
0034628426
-
Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
-
PMID:10666429
-
Kyne L, Warny M, Qamar A, Kelly CP. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med 2000; 342:390-7; PMID:10666429; http://dx.doi.org/10.1056/NEJM200002103420604
-
(2000)
N Engl J Med
, vol.342
, pp. 390-397
-
-
Kyne, L.1
Warny, M.2
Qamar, A.3
Kelly, C.P.4
-
31
-
-
0035915688
-
Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
-
PMID:11213096
-
Kyne L, Warny M, Qamar A, Kelly CP. Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 2001; 357:189-93; PMID:11213096; http://dx.doi.org/10.1016/S0140-6736(00) 03592-3
-
(2001)
Lancet
, vol.357
, pp. 189-193
-
-
Kyne, L.1
Warny, M.2
Qamar, A.3
Kelly, C.P.4
-
32
-
-
33847618667
-
Narrative review: The new epidemic of Clostridium difficile-associated enteric disease
-
PMID:17116920
-
Bartlett JG. Narrative review: the new epidemic of Clostridium difficile-associated enteric disease. Ann Intern Med 2006; 145:758-64; PMID:17116920; http://dx.doi.org/10.7326/0003-4819-145-10-200611210-00008
-
(2006)
Ann Intern Med
, vol.145
, pp. 758-764
-
-
Bartlett, J.G.1
-
33
-
-
0242509106
-
Frequency of binary toxin genes among Clostridium difficile strains that do not produce large clostridial toxins
-
PMID:14605169
-
Geric B, Johnson S, Gerding DN, Grabnar M, Rupnik M. Frequency of binary toxin genes among Clostridium difficile strains that do not produce large clostridial toxins. J Clin Microbiol 2003; 41:5227-32; PMID:14605169; http://dx.doi.org/10.1128/JCM.41.11.5227-5232.2003
-
(2003)
J Clin Microbiol
, vol.41
, pp. 5227-5232
-
-
Geric, B.1
Johnson, S.2
Gerding, D.N.3
Grabnar, M.4
Rupnik, M.5
-
34
-
-
0034607782
-
Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile
-
PMID:10802189
-
Stubbs S, Rupnik M, Gibert M, Brazier J, Duerden B, Popoff M. Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile. FEMS Microbiol Lett 2000; 186:307-12; PMID:10802189; http://dx.doi.org/10.1111/j.1574-6968.2000.tb09122.x
-
(2000)
FEMS Microbiol Lett
, vol.186
, pp. 307-312
-
-
Stubbs, S.1
Rupnik, M.2
Gibert, M.3
Brazier, J.4
Duerden, B.5
Popoff, M.6
-
35
-
-
2442420091
-
Prevalence and characterization of a binary toxin (actin-specific ADP-ribosyltransferase) from Clostridium difficile
-
PMID:15131151
-
Gonçalves C, Decré D, Barbut F, Burghoffer B, Petit JC. Prevalence and characterization of a binary toxin (actin-specific ADP-ribosyltransferase) from Clostridium difficile. J Clin Microbiol 2004; 42:1933-9; PMID:15131151; http://dx.doi.org/10.1128/JCM.42.5.1933-1939.2004
-
(2004)
J Clin Microbiol
, vol.42
, pp. 1933-1939
-
-
Gonçalves, C.1
Decré, D.2
Barbut, F.3
Burghoffer, B.4
Petit, J.C.5
-
36
-
-
53749091415
-
Characterization of Clostridium difficile strains isolated from patients in Ontario, Canada, from 2004 to 2006
-
PMID:18650360
-
Martin H, Willey B, Low DE, Staempfli HR, McGeer A, Boerlin P, Mulvey M, Weese JS. Characterization of Clostridium difficile strains isolated from patients in Ontario, Canada, from 2004 to 2006. J Clin Microbiol 2008; 46:2999-3004; PMID:18650360; http://dx.doi.org/10.1128/JCM.02437-07
-
(2008)
J Clin Microbiol
, vol.46
, pp. 2999-3004
-
-
Martin, H.1
Willey, B.2
Low, D.E.3
Staempfli, H.R.4
McGeer, A.5
Boerlin, P.6
Mulvey, M.7
Weese, J.S.8
-
37
-
-
4544264417
-
Binary bacterial toxins: Biochemistry, biology, and applications of common Clostridium and Bacillus proteins
-
table of contents.. PMID:15353562
-
Barth H, Aktories K, Popoff MR, Stiles BG. Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins. [table of contents.]. Microbiol Mol Biol Rev 2004; 68:373-402; PMID:15353562; http://dx.doi.org/10.1128/MMBR.68.3.373-402.2004
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 373-402
-
-
Barth, H.1
Aktories, K.2
Popoff, M.R.3
Stiles, B.G.4
-
38
-
-
80053636077
-
Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)
-
PMID:21930894
-
Papatheodorou P, Carette JE, Bell GW, Schwan C, Guttenberg G, Brummelkamp TR, Aktories K. Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT). Proc Natl Acad Sci U S A 2011; 108:16422-7; PMID:21930894; http://dx.doi.org/10.1073/ pnas.1109772108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16422-16427
-
-
Papatheodorou, P.1
Carette, J.E.2
Bell, G.W.3
Schwan, C.4
Guttenberg, G.5
Brummelkamp, T.R.6
Aktories, K.7
-
39
-
-
84863782095
-
Bidirectional attack on the actin cytoskeleton. Bacterial protein toxins causing polymerization or depolymerization of actin
-
PMID:22543189
-
Aktories K, Schwan C, Papatheodorou P, Lang AE. Bidirectional attack on the actin cytoskeleton. Bacterial protein toxins causing polymerization or depolymerization of actin. Toxicon 2012; 60:572-81; PMID:22543189; http://dx.doi.org/10.1016/j.toxicon.2012.04.338
-
(2012)
Toxicon
, vol.60
, pp. 572-581
-
-
Aktories, K.1
Schwan, C.2
Papatheodorou, P.3
Lang, A.E.4
-
40
-
-
73449097193
-
Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria
-
PMID:19834554
-
Schwan C, Stecher B, Tzivelekidis T, van Ham M, Rohde M, Hardt WD, Wehland J, Aktories K. Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. PLoS Pathog 2009; 5:e1000626; PMID:19834554; http://dx.doi.org/10.1371/journal.ppat.1000626
-
(2009)
PLoS Pathog
, vol.5
-
-
Schwan, C.1
Stecher, B.2
Tzivelekidis, T.3
Van Ham, M.4
Rohde, M.5
Hardt, W.D.6
Wehland, J.7
Aktories, K.8
-
41
-
-
4544379887
-
Distribution of Clostridium difficile variant toxinotypes and strains with binary toxin genes among clinical isolates in an American hospital
-
PMID:15314196
-
Geric B, Rupnik M, Gerding DN, Grabnar M, Johnson S. Distribution of Clostridium difficile variant toxinotypes and strains with binary toxin genes among clinical isolates in an American hospital. J Med Microbiol 2004; 53:887-94; PMID:15314196; http://dx.doi.org/10.1099/jmm.0.45610-0
-
(2004)
J Med Microbiol
, vol.53
, pp. 887-894
-
-
Geric, B.1
Rupnik, M.2
Gerding, D.N.3
Grabnar, M.4
Johnson, S.5
-
42
-
-
80053253206
-
Biology of Clostridium difficile: Implications for epidemiology and diagnosis
-
PMID:21682645
-
Carroll KC, Bartlett JG. Biology of Clostridium difficile: implications for epidemiology and diagnosis. Annu Rev Microbiol 2011; 65:501-21; PMID:21682645; http://dx.doi.org/10.1146/annurev-micro-090110-102824
-
(2011)
Annu Rev Microbiol
, vol.65
, pp. 501-521
-
-
Carroll, K.C.1
Bartlett, J.G.2
-
43
-
-
84882671647
-
Severe Clostridium difficile infection in New Zealand associated with an emerging strain, PCR-ribotype 244
-
PMID:24126745
-
De Almeida MN, Heffernan H, Dervan A, Bakker S, Freeman JT, Bhally H, Taylor SL, Riley TV, Roberts SA. Severe Clostridium difficile infection in New Zealand associated with an emerging strain, PCR-ribotype 244. N Z Med J 2013; 126:9-14; PMID:24126745
-
(2013)
N Z Med J
, vol.126
, pp. 9-14
-
-
De Almeida, M.N.1
Heffernan, H.2
Dervan, A.3
Bakker, S.4
Freeman, J.T.5
Bhally, H.6
Taylor, S.L.7
Riley, T.V.8
Roberts, S.A.9
-
44
-
-
20144363690
-
Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actinspecific ADP-ribosyltransferase)-producing strains
-
PMID:15673514
-
Barbut F, Decré D, Lalande V, Burghoffer B, Noussair L, Gigandon A, Espinasse F, Raskine L, Robert J, Mangeol A, et al. Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actinspecific ADP-ribosyltransferase)-producing strains. J Med Microbiol 2005; 54:181-5; PMID:15673514; http://dx.doi.org/10.1099/jmm.0.45804-0
-
(2005)
J Med Microbiol
, vol.54
, pp. 181-185
-
-
Barbut, F.1
Decré, D.2
Lalande, V.3
Burghoffer, B.4
Noussair, L.5
Gigandon, A.6
Espinasse, F.7
Raskine, L.8
Robert, J.9
Mangeol, A.10
-
45
-
-
79957640579
-
Binary toxin and death after Clostridium difficile infection
-
PMID:21749757
-
Bacci S, Mølbak K, Kjeldsen MK, Olsen KE. Binary toxin and death after Clostridium difficile infection. Emerg Infect Dis 2011; 17:976-82; PMID:21749757; http://dx.doi.org/10.3201/eid/1706.101483
-
(2011)
Emerg Infect Dis
, vol.17
, pp. 976-982
-
-
Bacci, S.1
Mølbak, K.2
Kjeldsen, M.K.3
Olsen, K.E.4
-
46
-
-
28844494086
-
An epidemic, toxin gene-variant strain of Clostridium difficile
-
PMID:16322603
-
McDonald LC, Killgore GE, Thompson A, Owens RC Jr., Kazakova SV, Sambol SP, Johnson S, Gerding DN. An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med 2005; 353:2433-41; PMID:16322603; http://dx.doi.org/10. 1056/NEJMoa051590
-
(2005)
N Engl J Med
, vol.353
, pp. 2433-2441
-
-
McDonald, L.C.1
Killgore, G.E.2
Thompson, A.3
Owens Jr., R.C.4
Kazakova, S.V.5
Sambol, S.P.6
Johnson, S.7
Gerding, D.N.8
-
47
-
-
84871951172
-
Predicting recurrence of C. difficile colitis using bacterial virulence factors: Binary toxin is the key
-
discussion 124-5; PMID:23086451
-
Stewart DB, Berg A, Hegarty J. Predicting recurrence of C. difficile colitis using bacterial virulence factors: binary toxin is the key. J Gastrointest Surg 2013; 17:118-24, discussion 124-5; PMID:23086451; http://dx.doi.org/10.1007/s11605-012-2056-6
-
(2013)
J Gastrointest Surg
, vol.17
, pp. 118-124
-
-
Stewart, D.B.1
Berg, A.2
Hegarty, J.3
-
48
-
-
45249099998
-
Increase in adult Clostridium difficile-related hospitalizations and case-fatality rate, United States, 2000-2005
-
PMID:18507904
-
Zilberberg MD, Shorr AF, Kollef MH. Increase in adult Clostridium difficile-related hospitalizations and case-fatality rate, United States, 2000-2005. Emerg Infect Dis 2008; 14:929-31; PMID:18507904; http://dx.doi.org/ 10.3201/eid1406.071447
-
(2008)
Emerg Infect Dis
, vol.14
, pp. 929-931
-
-
Zilberberg, M.D.1
Shorr, A.F.2
Kollef, M.H.3
-
49
-
-
4444382260
-
Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: A changing pattern of disease severity
-
PMID:15337727
-
Pépin J, Valiquette L, Alary ME, Villemure P, Pelletier A, Forget K, Pépin K, Chouinard D. Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. CMAJ 2004; 171:466-72; PMID:15337727; http://dx.doi.org/10.1503/cmaj.1041104
-
(2004)
CMAJ
, vol.171
, pp. 466-472
-
-
Pépin, J.1
Valiquette, L.2
Alary, M.E.3
Villemure, P.4
Pelletier, A.5
Forget, K.6
Pépin, K.7
Chouinard, D.8
-
50
-
-
27444437759
-
Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: A cohort study during an epidemic in Quebec
-
PMID:16206099
-
Pépin J, Saheb N, Coulombe MA, Alary ME, Corriveau MP, Authier S, Leblanc M, Rivard G, Bettez M, Primeau V, et al. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec. Clin Infect Dis 2005; 41:1254-60; PMID:16206099; http://dx.doi.org/10.1086/496986
-
(2005)
Clin Infect Dis
, vol.41
, pp. 1254-1260
-
-
Pépin, J.1
Saheb, N.2
Coulombe, M.A.3
Alary, M.E.4
Corriveau, M.P.5
Authier, S.6
Leblanc, M.7
Rivard, G.8
Bettez, M.9
Primeau, V.10
-
51
-
-
28844441314
-
A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
-
PMID:16322602
-
Loo VG, Poirier L, Miller MA, Oughton M, Libman MD, Michaud S, Bourgault AM, Nguyen T, Frenette C, Kelly M, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005; 353:2442-9; PMID:16322602; http://dx.doi.org/10.1056/NEJMoa051639
-
(2005)
N Engl J Med
, vol.353
, pp. 2442-2449
-
-
Loo, V.G.1
Poirier, L.2
Miller, M.A.3
Oughton, M.4
Libman, M.D.5
Michaud, S.6
Bourgault, A.M.7
Nguyen, T.8
Frenette, C.9
Kelly, M.10
-
52
-
-
78650825355
-
Clostridium difficile infection in Europe: A hospital-based survey
-
ECDIS Study Group PMID:21084111
-
Bauer MP, Notermans DW, van Benthem BH, Brazier JS, Wilcox MH, Rupnik M, Monnet DL, van Dissel JT, Kuijper EJ; ECDIS Study Group. Clostridium difficile infection in Europe: a hospital-based survey. Lancet 2011; 377:63-73; PMID:21084111; http://dx.doi.org/10.1016/S0140-6736(10)61266-4
-
(2011)
Lancet
, vol.377
, pp. 63-73
-
-
Bauer, M.P.1
Notermans, D.W.2
Van Benthem, B.H.3
Brazier, J.S.4
Wilcox, M.H.5
Rupnik, M.6
Monnet, D.L.7
Van Dissel, J.T.8
Kuijper, E.J.9
-
53
-
-
62249088494
-
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008
-
PMID:18761903
-
Kuijper EJ, Barbut F, Brazier JS, Kleinkauf N, Eckmanns T, Lambert ML, Drudy D, Fitzpatrick F, Wiuff C, Brown DJ, et al. Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008. Euro Surveill 2008; 13:18942; PMID:18761903
-
(2008)
Euro Surveill
, vol.13
, pp. 18942
-
-
Kuijper, E.J.1
Barbut, F.2
Brazier, J.S.3
Kleinkauf, N.4
Eckmanns, T.5
Lambert, M.L.6
Drudy, D.7
Fitzpatrick, F.8
Wiuff, C.9
Brown, D.J.10
-
54
-
-
33748563622
-
Emergence of Clostridium difficile-associated disease in North America and Europe
-
ESCMID Study Group for Clostridium difficile; EU Member States; European Centre for Disease Prevention and Control PMID:16965399
-
Kuijper EJ, Coignard B, Tüll P; ESCMID Study Group for Clostridium difficile; EU Member States; European Centre for Disease Prevention and Control. Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect 2006; 12(Suppl 6):2-18; PMID:16965399; http://dx.doi.org/10.1111/j.1469-0691.2006.01580.x
-
(2006)
Clin Microbiol Infect
, vol.12
, Issue.SUPPL. 6
, pp. 2-18
-
-
Kuijper, E.J.1
Coignard, B.2
Tüll, P.3
-
55
-
-
77953809436
-
A review of mortality due to Clostridium difficile infection
-
PMID:20361997
-
Karas JA, Enoch DA, Aliyu SH. A review of mortality due to Clostridium difficile infection. J Infect 2010; 61:1-8; PMID:20361997; http://dx.doi.org/10. 1016/j.jinf.2010.03.025
-
(2010)
J Infect
, vol.61
, pp. 1-8
-
-
Karas, J.A.1
Enoch, D.A.2
Aliyu, S.H.3
-
56
-
-
84890429802
-
The changing epidemiology of Clostridium difficile infection
-
PMID:24285002
-
Honda H, Dubberke ER. The changing epidemiology of Clostridium difficile infection. Curr Opin Gastroenterol 2014; 30:54-62; PMID:24285002; http://dx.doi.org/10.1097/MOG.0000000000000018
-
(2014)
Curr Opin Gastroenterol
, vol.30
, pp. 54-62
-
-
Honda, H.1
Dubberke, E.R.2
-
57
-
-
25144469664
-
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
-
PMID:16182895
-
Warny M, Pepin J, Fang A, Killgore G, Thompson A, Brazier J, Frost E, McDonald LC. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 2005; 366:1079-84; PMID:16182895; http://dx.doi.org/10.1016/S0140-6736(05)67420- X
-
(2005)
Lancet
, vol.366
, pp. 1079-1084
-
-
Warny, M.1
Pepin, J.2
Fang, A.3
Killgore, G.4
Thompson, A.5
Brazier, J.6
Frost, E.7
McDonald, L.C.8
-
58
-
-
42449157632
-
Increased sporulation rate of epidemic Clostridium difficile Type 027/NAP1
-
PMID:18287318
-
Akerlund T, Persson I, Unemo M, Norén T, Svenungsson B, Wullt M, Burman LG. Increased sporulation rate of epidemic Clostridium difficile Type 027/NAP1. J Clin Microbiol 2008; 46:1530-3; PMID:18287318; http://dx.doi.org/10. 1128/JCM.01964-07
-
(2008)
J Clin Microbiol
, vol.46
, pp. 1530-1533
-
-
Akerlund, T.1
Persson, I.2
Unemo, M.3
Norén, T.4
Svenungsson, B.5
Wullt, M.6
Burman, L.G.7
-
59
-
-
1442327302
-
Clindamycin, cephalosporins, fluoroquinolones, and Clostridium difficile-associated diarrhea: This is an antimicrobial resistance problem
-
PMID:14986247
-
Gerding DN. Clindamycin, cephalosporins, fluoroquinolones, and Clostridium difficile-associated diarrhea: this is an antimicrobial resistance problem. Clin Infect Dis 2004; 38:646-8; PMID:14986247; http://dx.doi.org/10. 1086/382084
-
(2004)
Clin Infect Dis
, vol.38
, pp. 646-648
-
-
Gerding, D.N.1
-
60
-
-
84863651274
-
Predictors of first recurrence of Clostridium difficile infection: Implications for initial management
-
Infections in Oxfordshire Research Database. PMID:22752869
-
Eyre DW, Walker AS, Wyllie D, Dingle KE, Griffiths D, Finney J, O'Connor L, Vaughan A, Crook DW, Wilcox MH, et al.; Infections in Oxfordshire Research Database. Predictors of first recurrence of Clostridium difficile infection: implications for initial management. Clin Infect Dis 2012; 55(Suppl 2):S77-87; PMID:22752869; http://dx.doi.org/10.1093/cid/cis356
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Eyre, D.W.1
Walker, A.S.2
Wyllie, D.3
Dingle, K.E.4
Griffiths, D.5
Finney, J.6
O'Connor, L.7
Vaughan, A.8
Crook, D.W.9
Wilcox, M.H.10
-
61
-
-
39749170731
-
Clinical recognition and diagnosis of Clostridium difficile infection
-
PMID:18177217
-
Bartlett JG, Gerding DN. Clinical recognition and diagnosis of Clostridium difficile infection. Clin Infect Dis 2008; 46(Suppl 1):S12-8; PMID:18177217; http://dx.doi.org/10.1086/521863
-
(2008)
Clin Infect Dis
, vol.46
, Issue.SUPPL. 1
-
-
Bartlett, J.G.1
Gerding, D.N.2
-
62
-
-
70450250081
-
Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections
-
PMID:19825425
-
McFarland LV. Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections. Anaerobe 2009; 15:274-80; PMID:19825425; http://dx.doi.org/10.1016/j.anaerobe.2009.09.002
-
(2009)
Anaerobe
, vol.15
, pp. 274-280
-
-
McFarland, L.V.1
-
63
-
-
84858598560
-
Vital signs: Preventing Clostridium difficile infections
-
Centers for Disease Control and Prevention (CDC) PMID:22398844
-
Centers for Disease Control and Prevention (CDC). Vital signs: preventing Clostridium difficile infections. MMWR Morb Mortal Wkly Rep 2012; 61:157-62; PMID:22398844
-
(2012)
MMWR Morb Mortal Wkly Rep
, vol.61
, pp. 157-162
-
-
-
64
-
-
67349239352
-
Recurrent Clostridium difficile infection: A review of risk factors, treatments, and outcomes
-
PMID:19394704
-
Johnson S. Recurrent Clostridium difficile infection: a review of risk factors, treatments, and outcomes. J Infect 2009; 58:403-10; PMID:19394704; http://dx.doi.org/10.1016/j.jinf.2009.03.010
-
(2009)
J Infect
, vol.58
, pp. 403-410
-
-
Johnson, S.1
-
65
-
-
70649107673
-
European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Treatment guidance document for Clostridium difficile infection (CDI)
-
European Society of Clinical Microbiology and Infectious Diseases PMID:19929973
-
Bauer MP, Kuijper EJ, van Dissel JT; European Society of Clinical Microbiology and Infectious Diseases. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): treatment guidance document for Clostridium difficile infection (CDI). Clin Microbiol Infect 2009; 15:1067-79; PMID:19929973; http://dx.doi.org/10.1111/j.1469-0691.2009.03099.x
-
(2009)
Clin Microbiol Infect
, vol.15
, pp. 1067-1079
-
-
Bauer, M.P.1
Kuijper, E.J.2
Van Dissel, J.T.3
-
66
-
-
77951026738
-
Clinical practice guidelines for Clostridium difficile infection in adults: 2010 Update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA)
-
Society for Healthcare Epidemiology of America; Infectious Diseases Society of America PMID:20307191
-
Cohen SH, Gerding DN, Johnson S, Kelly CP, Loo VG, McDonald LC, Pepin J, Wilcox MH; Society for Healthcare Epidemiology of America; Infectious Diseases Society of America. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol 2010; 31:431-55; PMID:20307191; http://dx.doi.org/10. 1086/651706
-
(2010)
Infect Control Hosp Epidemiol
, vol.31
, pp. 431-455
-
-
Cohen, S.H.1
Gerding, D.N.2
Johnson, S.3
Kelly, C.P.4
Loo, V.G.5
McDonald, L.C.6
Pepin, J.7
Wilcox, M.H.8
-
67
-
-
80052719520
-
Best strategies in recurrent or persistent Clostridium difficile infection
-
PMID:21767157
-
Cocanour CS. Best strategies in recurrent or persistent Clostridium difficile infection. Surg Infect (Larchmt) 2011; 12:235-9; PMID:21767157; http://dx.doi.org/10.1089/sur.2010.080
-
(2011)
Surg Infect (Larchmt)
, vol.12
, pp. 235-239
-
-
Cocanour, C.S.1
-
68
-
-
84863923754
-
Decreased cure and increased recurrence rates for Clostridium difficile infection caused by the epidemic C. difficile BI strain
-
PMID:22523271
-
Petrella LA, Sambol SP, Cheknis A, Nagaro K, Kean Y, Sears PS, Babakhani F, Johnson S, Gerding DN. Decreased cure and increased recurrence rates for Clostridium difficile infection caused by the epidemic C. difficile BI strain. Clin Infect Dis 2012; 55:351-7; PMID:22523271; http://dx.doi.org/10.1093/cid/ cis430
-
(2012)
Clin Infect Dis
, vol.55
, pp. 351-357
-
-
Petrella, L.A.1
Sambol, S.P.2
Cheknis, A.3
Nagaro, K.4
Kean, Y.5
Sears, P.S.6
Babakhani, F.7
Johnson, S.8
Gerding, D.N.9
-
69
-
-
79551527297
-
Fidaxomicin versus vancomycin for Clostridium difficile infection
-
OPT-80-003 Clinical Study Group PMID:21288078
-
Louie TJ, Miller MA, Mullane KM, Weiss K, Lentnek A, Golan Y, Gorbach S, Sears P, Shue YK; OPT-80-003 Clinical Study Group. Fidaxomicin versus vancomycin for Clostridium difficile infection. N Engl J Med 2011; 364:422-31; PMID:21288078; http://dx.doi.org/10.1056/NEJMoa0910812
-
(2011)
N Engl J Med
, vol.364
, pp. 422-431
-
-
Louie, T.J.1
Miller, M.A.2
Mullane, K.M.3
Weiss, K.4
Lentnek, A.5
Golan, Y.6
Gorbach, S.7
Sears, P.8
Shue, Y.K.9
-
70
-
-
74849098405
-
Treatment with monoclonal antibodies against Clostridium difficile toxins
-
PMID:20089970
-
Lowy I, Molrine DC, Leav BA, Blair BM, Baxter R, Gerding DN, Nichol G, Thomas WD Jr., Leney M, Sloan S, et al. Treatment with monoclonal antibodies against Clostridium difficile toxins. N Engl J Med 2010; 362:197-205; PMID:20089970; http://dx.doi.org/10.1056/NEJMoa0907635
-
(2010)
N Engl J Med
, vol.362
, pp. 197-205
-
-
Lowy, I.1
Molrine, D.C.2
Leav, B.A.3
Blair, B.M.4
Baxter, R.5
Gerding, D.N.6
Nichol, G.7
Thomas Jr., W.D.8
Leney, M.9
Sloan, S.10
-
71
-
-
33644837200
-
Management and outcomes of a first recurrence of Clostridium difficile-associated disease in Quebec, Canada
-
PMID:16477549
-
Pépin J, Routhier S, Gagnon S, Brazeau I. Management and outcomes of a first recurrence of Clostridium difficile-associated disease in Quebec, Canada. Clin Infect Dis 2006; 42:758-64; PMID:16477549; http://dx.doi.org/10. 1086/501126
-
(2006)
Clin Infect Dis
, vol.42
, pp. 758-764
-
-
Pépin, J.1
Routhier, S.2
Gagnon, S.3
Brazeau, I.4
-
72
-
-
79958148446
-
Effective utilization of evolving methods for the laboratory diagnosis of Clostridium difficile infection
-
PMID:21628487
-
Kufelnicka AM, Kirn TJ. Effective utilization of evolving methods for the laboratory diagnosis of Clostridium difficile infection. Clin Infect Dis 2011; 52:1451-7; PMID:21628487; http://dx.doi.org/10.1093/cid/cir201
-
(2011)
Clin Infect Dis
, vol.52
, pp. 1451-1457
-
-
Kufelnicka, A.M.1
Kirn, T.J.2
-
73
-
-
0036311186
-
Breaking the cycle: Treatment strategies for 163 cases of recurrent Clostridium difficile disease
-
PMID:12135033
-
McFarland LV, Elmer GW, Surawicz CM. Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease. Am J Gastroenterol 2002; 97:1769-75; PMID:12135033; http://dx.doi.org/10.1111/j.1572- 0241.2002.05839.x
-
(2002)
Am J Gastroenterol
, vol.97
, pp. 1769-1775
-
-
McFarland, L.V.1
Elmer, G.W.2
Surawicz, C.M.3
-
74
-
-
32544446901
-
Severe Clostridium difficile-associated disease in populations previously at low risk - Four states, 2005
-
Centers for Disease Control and Prevention (CDC). PMID:16319813
-
Centers for Disease Control and Prevention (CDC). Severe Clostridium difficile-associated disease in populations previously at low risk - four states, 2005. MMWR Morb Mortal Wkly Rep 2005; 54:1201-5; PMID:16319813
-
(2005)
MMWR Morb Mortal Wkly Rep
, vol.54
, pp. 1201-1205
-
-
-
75
-
-
84855422347
-
The epidemiology of community-acquired Clostridium difficile infection: A population-based study
-
PMID:22108454
-
Khanna S, Pardi DS, Aronson SL, Kammer PP, Orenstein R, St Sauver JL, Harmsen WS, Zinsmeister AR. The epidemiology of community-acquired Clostridium difficile infection: a population-based study. Am J Gastroenterol 2012; 107:89-95; PMID:22108454; http://dx.doi.org/10.1038/ajg.2011.398
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 89-95
-
-
Khanna, S.1
Pardi, D.S.2
Aronson, S.L.3
Kammer, P.P.4
Orenstein, R.5
St Sauver, J.L.6
Harmsen, W.S.7
Zinsmeister, A.R.8
-
76
-
-
84863676446
-
Current status of Clostridium difficile infection epidemiology
-
PMID:22752867
-
Lessa FC, Gould CV, McDonald LC. Current status of Clostridium difficile infection epidemiology. Clin Infect Dis 2012; 55(Suppl 2):S65-70; PMID:22752867; http://dx.doi.org/10.1093/cid/cis319
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Lessa, F.C.1
Gould, C.V.2
McDonald, L.C.3
-
77
-
-
77952569377
-
Hospital-based epidemiology: A strategy for 'dealing with Clostridium difficile'
-
PMID:19726105
-
Shears P, Prtak L, Duckworth R. Hospital-based epidemiology: a strategy for 'dealing with Clostridium difficile'. J Hosp Infect 2010; 74:319-25; PMID:19726105; http://dx.doi.org/10.1016/j.jhin.2009.07.009
-
(2010)
J Hosp Infect
, vol.74
, pp. 319-325
-
-
Shears, P.1
Prtak, L.2
Duckworth, R.3
-
78
-
-
84863694101
-
Burden of Clostridium difficile on the healthcare system
-
PMID:22752870
-
Dubberke ER, Olsen MA. Burden of Clostridium difficile on the healthcare system. Clin Infect Dis 2012; 55(Suppl 2):S88-92; PMID:22752870; http://dx.doi.org/10.1093/cid/cis335
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Dubberke, E.R.1
Olsen, M.A.2
-
79
-
-
0021995801
-
Effects of Clostridium difficile toxins given intragastrically to animals
-
PMID:3917975
-
Lyerly DM, Saum KE, MacDonald DK, Wilkins TD. Effects of Clostridium difficile toxins given intragastrically to animals. Infect Immun 1985; 47:349-52; PMID:3917975
-
(1985)
Infect Immun
, vol.47
, pp. 349-352
-
-
Lyerly, D.M.1
Saum, K.E.2
MacDonald, D.K.3
Wilkins, T.D.4
-
80
-
-
0023852615
-
Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro
-
PMID:3343050
-
Lima AA, Lyerly DM, Wilkins TD, Innes DJ, Guerrant RL. Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro. Infect Immun 1988; 56:582-8; PMID:3343050
-
(1988)
Infect Immun
, vol.56
, pp. 582-588
-
-
Lima, A.A.1
Lyerly, D.M.2
Wilkins, T.D.3
Innes, D.J.4
Guerrant, R.L.5
-
81
-
-
0022646133
-
Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon
-
PMID:3949240
-
Mitchell TJ, Ketley JM, Haslam SC, Stephen J, Burdon DW, Candy DC, Daniel R. Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon. Gut 1986; 27:78-85; PMID:3949240; http://dx.doi.org/10.1136/gut.27.1.78
-
(1986)
Gut
, vol.27
, pp. 78-85
-
-
Mitchell, T.J.1
Ketley, J.M.2
Haslam, S.C.3
Stephen, J.4
Burdon, D.W.5
Candy, D.C.6
Daniel, R.7
-
82
-
-
67349114409
-
Toxin B is essential for virulence of Clostridium difficile
-
PMID:19252482
-
Lyras D, O'Connor JR, Howarth PM, Sambol SP, Carter GP, Phumoonna T, Poon R, Adams V, Vedantam G, Johnson S, et al. Toxin B is essential for virulence of Clostridium difficile. Nature 2009; 458:1176-9; PMID:19252482; http://dx.doi.org/10.1038/nature07822
-
(2009)
Nature
, vol.458
, pp. 1176-1179
-
-
Lyras, D.1
O'Connor, J.R.2
Howarth, P.M.3
Sambol, S.P.4
Carter, G.P.5
Phumoonna, T.6
Poon, R.7
Adams, V.8
Vedantam, G.9
Johnson, S.10
-
83
-
-
74249096590
-
Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)
-
PMID:19941990
-
Leav BA, Blair B, Leney M, Knauber M, Reilly C, Lowy I, Gerding DN, Kelly CP, Katchar K, Baxter R, et al. Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI). Vaccine 2010; 28:965-9; PMID:19941990; http://dx.doi.org/10.1016/j.vaccine.2009.10.144
-
(2010)
Vaccine
, vol.28
, pp. 965-969
-
-
Leav, B.A.1
Blair, B.2
Leney, M.3
Knauber, M.4
Reilly, C.5
Lowy, I.6
Gerding, D.N.7
Kelly, C.P.8
Katchar, K.9
Baxter, R.10
-
84
-
-
84871775506
-
Antibody against TcdB, but not TcdA, prevents development of gastrointestinal and systemic Clostridium difficile disease
-
PMID:23125448
-
Steele J, Mukherjee J, Parry N, Tzipori S. Antibody against TcdB, but not TcdA, prevents development of gastrointestinal and systemic Clostridium difficile disease. J Infect Dis 2013; 207:323-30; PMID:23125448; http://dx.doi.org/10.1093/infdis/jis669
-
(2013)
J Infect Dis
, vol.207
, pp. 323-330
-
-
Steele, J.1
Mukherjee, J.2
Parry, N.3
Tzipori, S.4
-
85
-
-
33845580482
-
Toxin A-negative, toxin B-positive Clostridium difficile
-
PMID:16857405
-
Drudy D, Fanning S, Kyne L. Toxin A-negative, toxin B-positive Clostridium difficile. Int J Infect Dis 2007; 11:5-10; PMID:16857405; http://dx.doi.org/10.1016/j.ijid.2006.04.003
-
(2007)
Int J Infect Dis
, vol.11
, pp. 5-10
-
-
Drudy, D.1
Fanning, S.2
Kyne, L.3
-
86
-
-
0034808952
-
Nosocomial outbreak of Clostridium difficile-associated diarrhoea due to a clindamycin-resistant enterotoxin A-negative strain
-
PMID:11681431
-
Kuijper EJ, de Weerdt J, Kato H, Kato N, van Dam AP, van der Vorm ER, Weel J, van Rheenen C, Dankert J. Nosocomial outbreak of Clostridium difficile-associated diarrhoea due to a clindamycin-resistant enterotoxin A-negative strain. Eur J Clin Microbiol Infect Dis 2001; 20:528-34; PMID:11681431; http://dx.doi.org/10.1007/s100960100550
-
(2001)
Eur J Clin Microbiol Infect Dis
, vol.20
, pp. 528-534
-
-
Kuijper, E.J.1
De Weerdt, J.2
Kato, H.3
Kato, N.4
Van Dam, A.P.5
Van Der Vorm, E.R.6
Weel, J.7
Van Rheenen, C.8
Dankert, J.9
-
87
-
-
1542723582
-
Characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates from outbreaks in different countries by amplified fragment length polymorphism and PCR ribotyping
-
PMID:15004050
-
van den Berg RJ, Claas EC, Oyib DH, Klaassen CH, Dijkshoorn L, Brazier JS, Kuijper EJ. Characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates from outbreaks in different countries by amplified fragment length polymorphism and PCR ribotyping. J Clin Microbiol 2004; 42:1035-41; PMID:15004050; http://dx.doi.org/10.1128/JCM.42.3.1035-1041. 2004
-
(2004)
J Clin Microbiol
, vol.42
, pp. 1035-1041
-
-
Van Den Berg, R.J.1
Claas, E.C.2
Oyib, D.H.3
Klaassen, C.H.4
Dijkshoorn, L.5
Brazier, J.S.6
Kuijper, E.J.7
-
88
-
-
77957988127
-
The role of toxin A and toxin B in Clostridium difficile infection
-
PMID:20844489
-
Kuehne SA, Cartman ST, Heap JT, Kelly ML, Cockayne A, Minton NP. The role of toxin A and toxin B in Clostridium difficile infection. Nature 2010; 467:711-3; PMID:20844489; http://dx.doi.org/10.1038/nature09397
-
(2010)
Nature
, vol.467
, pp. 711-713
-
-
Kuehne, S.A.1
Cartman, S.T.2
Heap, J.T.3
Kelly, M.L.4
Cockayne, A.5
Minton, N.P.6
-
89
-
-
0032962874
-
Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters
-
PMID:9916055
-
Giannasca PJ, Zhang ZX, Lei WD, Boden JA, Giel MA, Monath TP, Thomas WD Jr. Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters. Infect Immun 1999; 67:527-38; PMID:9916055
-
(1999)
Infect Immun
, vol.67
, pp. 527-538
-
-
Giannasca, P.J.1
Zhang, Z.X.2
Lei, W.D.3
Boden, J.A.4
Giel, M.A.5
Monath, T.P.6
Thomas Jr., W.D.7
-
90
-
-
84864916100
-
Protection against Clostridium difficile infection with broadly neutralizing antitoxin monoclonal antibodies
-
PMID:22732923
-
Marozsan AJ, Ma D, Nagashima KA, Kennedy BJ, Kang YK, Arrigale RR, Donovan GP, Magargal WW, Maddon PJ, Olson WC. Protection against Clostridium difficile infection with broadly neutralizing antitoxin monoclonal antibodies. J Infect Dis 2012; 206:706-13; PMID:22732923; http://dx.doi.org/10.1093/infdis/ jis416
-
(2012)
J Infect Dis
, vol.206
, pp. 706-713
-
-
Marozsan, A.J.1
Ma, D.2
Nagashima, K.A.3
Kennedy, B.J.4
Kang, Y.K.5
Arrigale, R.R.6
Donovan, G.P.7
Magargal, W.W.8
Maddon, P.J.9
Olson, W.C.10
-
91
-
-
0035145510
-
Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults
-
PMID:11159994
-
Kotloff KL, Wasserman SS, Losonsky GA, Thomas W Jr., Nichols R, Edelman R, Bridwell M, Monath TP. Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults. Infect Immun 2001; 69:988-95; PMID:11159994; http://dx.doi.org/10.1128/IAI.69.2.988- 995.2001
-
(2001)
Infect Immun
, vol.69
, pp. 988-995
-
-
Kotloff, K.L.1
Wasserman, S.S.2
Losonsky, G.A.3
Thomas Jr., W.4
Nichols, R.5
Edelman, R.6
Bridwell, M.7
Monath, T.P.8
-
92
-
-
33646690242
-
Tetanus vaccine
-
PMID:16710950
-
Tetanus vaccine. Wkly Epidemiol Rec 2006; 81:198-208; PMID:16710950
-
(2006)
Wkly Epidemiol Rec
, vol.81
, pp. 198-208
-
-
-
93
-
-
33646198569
-
Diphtheria vaccine
-
PMID:16671240
-
Diphtheria vaccine. Wkly Epidemiol Rec 2006; 81:24-32; PMID:16671240
-
(2006)
Wkly Epidemiol Rec
, vol.81
, pp. 24-32
-
-
-
94
-
-
0020029308
-
Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters
-
PMID:7085078
-
Libby JM, Jortner BS, Wilkins TD. Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters. Infect Immun 1982; 36:822-9; PMID:7085078
-
(1982)
Infect Immun
, vol.36
, pp. 822-829
-
-
Libby, J.M.1
Jortner, B.S.2
Wilkins, T.D.3
-
95
-
-
0023503051
-
Immunization of adult hamsters against Clostridium difficile-associated ileocecitis and transfer of protection to infant hamsters
-
PMID:3679541
-
Kim PH, Iaconis JP, Rolfe RD. Immunization of adult hamsters against Clostridium difficile-associated ileocecitis and transfer of protection to infant hamsters. Infect Immun 1987; 55:2984-92; PMID:3679541
-
(1987)
Infect Immun
, vol.55
, pp. 2984-2992
-
-
Kim, P.H.1
Iaconis, J.P.2
Rolfe, R.D.3
-
96
-
-
0028818809
-
Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters
-
PMID:7591115
-
Torres JF, Lyerly DM, Hill JE, Monath TP. Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters. Infect Immun 1995; 63:4619-27; PMID:7591115
-
(1995)
Infect Immun
, vol.63
, pp. 4619-4627
-
-
Torres, J.F.1
Lyerly, D.M.2
Hill, J.E.3
Monath, T.P.4
-
97
-
-
34249891873
-
Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A-neutralizing antibodies in mice
-
PMID:17371854
-
Ghose C, Kalsy A, Sheikh A, Rollenhagen J, John M, Young J, Rollins SM, Qadri F, Calderwood SB, Kelly CP, et al. Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A-neutralizing antibodies in mice. Infect Immun 2007; 75:2826-32; PMID:17371854; http://dx.doi.org/10.1128/IAI.00127-07
-
(2007)
Infect Immun
, vol.75
, pp. 2826-2832
-
-
Ghose, C.1
Kalsy, A.2
Sheikh, A.3
Rollenhagen, J.4
John, M.5
Young, J.6
Rollins, S.M.7
Qadri, F.8
Calderwood, S.B.9
Kelly, C.P.10
-
98
-
-
84555187507
-
Vaccination with parenteral toxoid B protects hamsters against lethal challenge with toxin A-negative, toxin B-positive clostridium difficile but does not prevent colonization
-
PMID:22124129
-
Siddiqui F, O'Connor JR, Nagaro K, Cheknis A, Sambol SP, Vedantam G, Gerding DN, Johnson S. Vaccination with parenteral toxoid B protects hamsters against lethal challenge with toxin A-negative, toxin B-positive clostridium difficile but does not prevent colonization. J Infect Dis 2012; 205:128-33; PMID:22124129; http://dx.doi.org/10.1093/infdis/jir688
-
(2012)
J Infect Dis
, vol.205
, pp. 128-133
-
-
Siddiqui, F.1
O'Connor, J.R.2
Nagaro, K.3
Cheknis, A.4
Sambol, S.P.5
Vedantam, G.6
Gerding, D.N.7
Johnson, S.8
-
99
-
-
0037369921
-
Clostridium difficile vaccine and serum immunoglobulin G antibody response to toxin A
-
PMID:12595488
-
Aboudola S, Kotloff KL, Kyne L, Warny M, Kelly EC, Sougioultzis S, Giannasca PJ, Monath TP, Kelly CP. Clostridium difficile vaccine and serum immunoglobulin G antibody response to toxin A. Infect Immun 2003; 71:1608-10; PMID:12595488; http://dx.doi.org/10.1128/IAI.71.3.1608-1610.2003
-
(2003)
Infect Immun
, vol.71
, pp. 1608-1610
-
-
Aboudola, S.1
Kotloff, K.L.2
Kyne, L.3
Warny, M.4
Kelly, E.C.5
Sougioultzis, S.6
Giannasca, P.J.7
Monath, T.P.8
Kelly, C.P.9
-
100
-
-
20244383137
-
Clostridium difficile toxoid vaccine in recurrent C. difficile-associated diarrhea
-
PMID:15765411
-
Sougioultzis S, Kyne L, Drudy D, Keates S, Maroo S, Pothoulakis C, Giannasca PJ, Lee CK, Warny M, Monath TP, et al. Clostridium difficile toxoid vaccine in recurrent C. difficile-associated diarrhea. Gastroenterology 2005; 128:764-70; PMID:15765411; http://dx.doi.org/10.1053/j.gastro.2004.11.004
-
(2005)
Gastroenterology
, vol.128
, pp. 764-770
-
-
Sougioultzis, S.1
Kyne, L.2
Drudy, D.3
Keates, S.4
Maroo, S.5
Pothoulakis, C.6
Giannasca, P.J.7
Lee, C.K.8
Warny, M.9
Monath, T.P.10
-
101
-
-
84881586501
-
Systemic antibody responses induced by a two-component Clostridium difficile toxoid vaccine protect against C. difficile-associated disease in hamsters
-
PMID:23518659
-
Anosova NG, Brown AM, Li L, Liu N, Cole LE, Zhang J, Mehta H, Kleanthous H. Systemic antibody responses induced by a two-component Clostridium difficile toxoid vaccine protect against C. difficile-associated disease in hamsters. J Med Microbiol 2013; 62:1394-404; PMID:23518659; http://dx.doi.org/10.1099/jmm.0. 056796-0
-
(2013)
J Med Microbiol
, vol.62
, pp. 1394-1404
-
-
Anosova, N.G.1
Brown, A.M.2
Li, L.3
Liu, N.4
Cole, L.E.5
Zhang, J.6
Mehta, H.7
Kleanthous, H.8
-
102
-
-
84857793535
-
Phase I dose finding studies of an adjuvanted Clostridium difficile toxoid vaccine
-
PMID:22306375
-
Greenberg RN, Marbury TC, Foglia G, Warny M. Phase I dose finding studies of an adjuvanted Clostridium difficile toxoid vaccine. Vaccine 2012; 30:2245-9; PMID:22306375; http://dx.doi.org/10.1016/j.vaccine.2012.01.065
-
(2012)
Vaccine
, vol.30
, pp. 2245-2249
-
-
Greenberg, R.N.1
Marbury, T.C.2
Foglia, G.3
Warny, M.4
-
103
-
-
84861975931
-
Clostridium difficile: Development of a novel candidate vaccine
-
PMID:22682287
-
Foglia G, Shah S, Luxemburger C, Pietrobon PJ. Clostridium difficile: development of a novel candidate vaccine. Vaccine 2012; 30:4307-9; PMID:22682287; http://dx.doi.org/10.1016/j.vaccine.2012.01.056
-
(2012)
Vaccine
, vol.30
, pp. 4307-4309
-
-
Foglia, G.1
Shah, S.2
Luxemburger, C.3
Pietrobon, P.J.4
-
104
-
-
84879819430
-
A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile
-
PMID:23629868
-
Donald RG, Flint M, Kalyan N, Johnson E, Witko SE, Kotash C, Zhao P, Megati S, Yurgelonis I, Lee PK, et al. A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile. Microbiology 2013; 159:1254-66; PMID:23629868; http://dx.doi.org/10.1099/mic.0.066712-0
-
(2013)
Microbiology
, vol.159
, pp. 1254-1266
-
-
Donald, R.G.1
Flint, M.2
Kalyan, N.3
Johnson, E.4
Witko, S.E.5
Kotash, C.6
Zhao, P.7
Megati, S.8
Yurgelonis, I.9
Lee, P.K.10
-
105
-
-
0025967371
-
Properties of pertussis toxin mutant PT-9K/129G after formaldehyde treatment
-
PMID:1702767
-
Nencioni L, Volpini G, Peppoloni S, Bugnoli M, De Magistris T, Marsili I, Rappuoli R. Properties of pertussis toxin mutant PT-9K/129G after formaldehyde treatment. Infect Immun 1991; 59:625-30; PMID:1702767
-
(1991)
Infect Immun
, vol.59
, pp. 625-630
-
-
Nencioni, L.1
Volpini, G.2
Peppoloni, S.3
Bugnoli, M.4
De Magistris, T.5
Marsili, I.6
Rappuoli, R.7
-
106
-
-
0029881645
-
The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies
-
PMID:8735545
-
Ibsen PH. The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies. Vaccine 1996; 14:359-68; PMID:8735545; http://dx.doi.org/10.1016/ 0264-410X(95)00230-X
-
(1996)
Vaccine
, vol.14
, pp. 359-368
-
-
Ibsen, P.H.1
-
107
-
-
84883438006
-
Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB
-
PMID:23935501
-
Lanis JM, Heinlen LD, James JA, Ballard JD. Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB. PLoS Pathog 2013; 9:e1003523; PMID:23935501; http://dx.doi.org/10.1371/journal.ppat. 1003523
-
(2013)
PLoS Pathog
, vol.9
-
-
Lanis, J.M.1
Heinlen, L.D.2
James, J.A.3
Ballard, J.D.4
-
108
-
-
33947260554
-
Rho-glucosylating Clostridium difficile toxins A and B: New insights into structure and function
-
PMID:17237138
-
Jank T, Giesemann T, Aktories K. Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function. Glycobiology 2007; 17:15R-22R; PMID:17237138; http://dx.doi.org/10.1093/glycob/cwm004
-
(2007)
Glycobiology
, vol.17
-
-
Jank, T.1
Giesemann, T.2
Aktories, K.3
-
109
-
-
0025030511
-
Vaccination against lethal Clostridium difficile enterocolitis with a nontoxic recombinant peptide of toxin A
-
Lyerly DM. Vaccination against lethal Clostridium difficile enterocolitis with a nontoxic recombinant peptide of toxin A. Curr Microbiol 1990; 21:29-32; http://dx.doi.org/10.1007/BF02090096
-
(1990)
Curr Microbiol
, vol.21
, pp. 29-32
-
-
Lyerly, D.M.1
-
110
-
-
0030987748
-
Protective immunity against Clostridium difficile toxin A induced by oral immunization with a live, attenuated Vibrio cholerae vector strain
-
PMID:9199470
-
Ryan ET, Butterton JR, Smith RN, Carroll PA, Crean TI, Calderwood SB. Protective immunity against Clostridium difficile toxin A induced by oral immunization with a live, attenuated Vibrio cholerae vector strain. Infect Immun 1997; 65:2941-9; PMID:9199470
-
(1997)
Infect Immun
, vol.65
, pp. 2941-2949
-
-
Ryan, E.T.1
Butterton, J.R.2
Smith, R.N.3
Carroll, P.A.4
Crean, T.I.5
Calderwood, S.B.6
-
111
-
-
0032900382
-
Immunogenicity of a Salmonella typhimurium aroA aroD vaccine expressing a nontoxic domain of Clostridium difficile toxin A
-
PMID:10225867
-
Ward SJ, Douce G, Figueiredo D, Dougan G, Wren BW. Immunogenicity of a Salmonella typhimurium aroA aroD vaccine expressing a nontoxic domain of Clostridium difficile toxin A. Infect Immun 1999; 67:2145-52; PMID:10225867
-
(1999)
Infect Immun
, vol.67
, pp. 2145-2152
-
-
Ward, S.J.1
Douce, G.2
Figueiredo, D.3
Dougan, G.4
Wren, B.W.5
-
112
-
-
0032829877
-
Local and systemic neutralizing antibody responses induced by intranasal immunization with the nontoxic binding domain of toxin A from Clostridium difficile
-
PMID:10496886
-
Ward SJ, Douce G, Dougan G, Wren BW. Local and systemic neutralizing antibody responses induced by intranasal immunization with the nontoxic binding domain of toxin A from Clostridium difficile. Infect Immun 1999; 67:5124-32; PMID:10496886
-
(1999)
Infect Immun
, vol.67
, pp. 5124-5132
-
-
Ward, S.J.1
Douce, G.2
Dougan, G.3
Wren, B.W.4
-
113
-
-
79959449569
-
Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B
-
PMID:21482682
-
Permpoonpattana P, Hong HA, Phetcharaburanin J, Huang JM, Cook J, Fairweather NF, Cutting SM. Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B. Infect Immun 2011; 79:2295-302; PMID:21482682; http://dx.doi.org/10.1128/IAI.00130-11
-
(2011)
Infect Immun
, vol.79
, pp. 2295-2302
-
-
Permpoonpattana, P.1
Hong, H.A.2
Phetcharaburanin, J.3
Huang, J.M.4
Cook, J.5
Fairweather, N.F.6
Cutting, S.M.7
-
114
-
-
0020066824
-
Production of antitoxins to two toxins of Clostridium difficile and immunological comparison of the toxins by cross-neutralization studies
-
PMID:6172384
-
Libby JM, Wilkins TD. Production of antitoxins to two toxins of Clostridium difficile and immunological comparison of the toxins by cross-neutralization studies. Infect Immun 1982; 35:374-6; PMID:6172384
-
(1982)
Infect Immun
, vol.35
, pp. 374-376
-
-
Libby, J.M.1
Wilkins, T.D.2
-
115
-
-
84880837675
-
Protective efficacy induced by recombinant Clostridium difficile toxin fragments
-
PMID:23716610
-
Leuzzi R, Spencer J, Buckley A, Brettoni C, Martinelli M, Tulli L, Marchi S, Luzzi E, Irvine J, Candlish D, et al. Protective efficacy induced by recombinant Clostridium difficile toxin fragments. Infect Immun 2013; 81:2851-60; PMID:23716610; http://dx.doi.org/10.1128/IAI.01341-12
-
(2013)
Infect Immun
, vol.81
, pp. 2851-2860
-
-
Leuzzi, R.1
Spencer, J.2
Buckley, A.3
Brettoni, C.4
Martinelli, M.5
Tulli, L.6
Marchi, S.7
Luzzi, E.8
Irvine, J.9
Candlish, D.10
-
116
-
-
84864821779
-
A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection
-
PMID:22615245
-
Wang H, Sun X, Zhang Y, Li S, Chen K, Shi L, Nie W, Kumar R, Tzipori S, Wang J, et al. A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection. Infect Immun 2012; 80:2678-88; PMID:22615245; http://dx.doi.org/10.1128/IAI.00215-12
-
(2012)
Infect Immun
, vol.80
, pp. 2678-2688
-
-
Wang, H.1
Sun, X.2
Zhang, Y.3
Li, S.4
Chen, K.5
Shi, L.6
Nie, W.7
Kumar, R.8
Tzipori, S.9
Wang, J.10
-
117
-
-
2142761566
-
Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant
-
PMID:15102793
-
Castagliuolo I, Sardina M, Brun P, DeRos C, Mastrotto C, Lovato L, Palù G. Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant. Infect Immun 2004; 72:2827-36; PMID:15102793; http://dx.doi.org/10.1128/IAI.72.5.2827-2836.2004
-
(2004)
Infect Immun
, vol.72
, pp. 2827-2836
-
-
Castagliuolo, I.1
Sardina, M.2
Brun, P.3
DeRos, C.4
Mastrotto, C.5
Lovato, L.6
Palù, G.7
-
118
-
-
67349187243
-
A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A
-
PMID:19464540
-
Gardiner DF, Rosenberg T, Zaharatos J, Franco D, Ho DD. A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A. Vaccine 2009; 27:3598-604; PMID:19464540; http://dx.doi.org/10.1016/j.vaccine.2009.03. 058
-
(2009)
Vaccine
, vol.27
, pp. 3598-3604
-
-
Gardiner, D.F.1
Rosenberg, T.2
Zaharatos, J.3
Franco, D.4
Ho, D.D.5
-
119
-
-
84856570281
-
Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice
-
PMID:22200503
-
Seregin SS, Aldhamen YA, Rastall DP, Godbehere S, Amalfitano A. Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice. Vaccine 2012; 30:1492-501; PMID:22200503; http://dx.doi.org/10.1016/j. vaccine.2011.12.064
-
(2012)
Vaccine
, vol.30
, pp. 1492-1501
-
-
Seregin, S.S.1
Aldhamen, Y.A.2
Rastall, D.P.3
Godbehere, S.4
Amalfitano, A.5
-
120
-
-
84861661669
-
A novel fusion protein containing the receptor binding domains of C. difficile toxin A and toxin B elicits protective immunity against lethal toxin and spore challenge in preclinical efficacy models
-
PMID:22537987
-
Tian JH, Fuhrmann SR, Kluepfel-Stahl S, Carman RJ, Ellingsworth L, Flyer DC. A novel fusion protein containing the receptor binding domains of C. difficile toxin A and toxin B elicits protective immunity against lethal toxin and spore challenge in preclinical efficacy models. Vaccine 2012; 30:4249-58; PMID:22537987; http://dx.doi.org/10.1016/j.vaccine.2012.04.045
-
(2012)
Vaccine
, vol.30
, pp. 4249-4258
-
-
Tian, J.H.1
Fuhrmann, S.R.2
Kluepfel-Stahl, S.3
Carman, R.J.4
Ellingsworth, L.5
Flyer, D.C.6
-
121
-
-
84877800051
-
Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse model of Clostridium difficile disease
-
PMID:23545305
-
Ghose C, Verhagen JM, Chen X, Yu J, Huang Y, Chenesseau O, Kelly CP, Ho DD. Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse model of Clostridium difficile disease. Infect Immun 2013; 81:2190-6; PMID:23545305; http://dx.doi.org/10.1128/IAI.01074-12
-
(2013)
Infect Immun
, vol.81
, pp. 2190-2196
-
-
Ghose, C.1
Verhagen, J.M.2
Chen, X.3
Yu, J.4
Huang, Y.5
Chenesseau, O.6
Kelly, C.P.7
Ho, D.D.8
-
122
-
-
84873413568
-
Clostridium difficile flagellin stimulates tolllike receptor 5, and toxin B promotes flagellin-induced chemokine production via TLR5
-
PMID:23261530
-
Yoshino Y, Kitazawa T, Ikeda M, Tatsuno K, Yanagimoto S, Okugawa S, Yotsuyanagi H, Ota Y. Clostridium difficile flagellin stimulates tolllike receptor 5, and toxin B promotes flagellin-induced chemokine production via TLR5. Life Sci 2013; 92:211-7; PMID:23261530; http://dx.doi.org/10.1016/j.lfs. 2012.11.017
-
(2013)
Life Sci
, vol.92
, pp. 211-217
-
-
Yoshino, Y.1
Kitazawa, T.2
Ikeda, M.3
Tatsuno, K.4
Yanagimoto, S.5
Okugawa, S.6
Yotsuyanagi, H.7
Ota, Y.8
-
123
-
-
0030931082
-
Toxins A and B from Clostridium difficile differ with respect to enzymatic potencies, cellular substrate specificities, and surface binding to cultured cells
-
PMID:9312171
-
Chaves-Olarte E, Weidmann M, Eichel-Streiber C, Thelestam M. Toxins A and B from Clostridium difficile differ with respect to enzymatic potencies, cellular substrate specificities, and surface binding to cultured cells. J Clin Invest 1997; 100:1734-41; PMID:9312171; http://dx.doi.org/10.1172/JCI119698
-
(1997)
J Clin Invest
, vol.100
, pp. 1734-1741
-
-
Chaves-Olarte, E.1
Weidmann, M.2
Eichel-Streiber, C.3
Thelestam, M.4
-
124
-
-
45249088074
-
Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences
-
PMID:18480336
-
Stabler RA, Dawson LF, Phua LT, Wren BW. Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. J Med Microbiol 2008; 57:771-5; PMID:18480336; http://dx.doi.org/10. 1099/jmm.0.47743-0
-
(2008)
J Med Microbiol
, vol.57
, pp. 771-775
-
-
Stabler, R.A.1
Dawson, L.F.2
Phua, L.T.3
Wren, B.W.4
-
125
-
-
84874742257
-
Protective antibody responses against Clostridium difficile elicited by a DNA vaccine expressing the enzymatic domain of toxin B
-
PMID:23143772
-
Jin K, Wang S, Zhang C, Xiao Y, Lu S, Huang Z. Protective antibody responses against Clostridium difficile elicited by a DNA vaccine expressing the enzymatic domain of toxin B. Hum Vaccin Immunother 2013; 9:63-73; PMID:23143772; http://dx.doi.org/10.4161/hv.22434
-
(2013)
Hum Vaccin Immunother
, vol.9
, pp. 63-73
-
-
Jin, K.1
Wang, S.2
Zhang, C.3
Xiao, Y.4
Lu, S.5
Huang, Z.6
-
126
-
-
84872017421
-
Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism
-
PMID:23236283
-
Chumbler NM, Farrow MA, Lapierre LA, Franklin JL, Haslam DB, Goldenring JR, Lacy DB. Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism. PLoS Pathog 2012; 8:e1003072; PMID:23236283; http://dx.doi.org/10.1371/journal.ppat.1003072
-
(2012)
PLoS Pathog
, vol.8
-
-
Chumbler, N.M.1
Farrow, Ma.2
Lapierre, L.A.3
Franklin, J.L.4
Haslam, D.B.5
Goldenring, J.R.6
Lacy, D.B.7
-
127
-
-
84887476533
-
Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex
-
Farrow MA, Chumbler NM, Lapierre LA, Franklin JL, Rutherford SA, Goldenring JR, Lacy DB. Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex. Proceedings of the National Academy of Sciences of the United States of America 2013.
-
Proceedings of the National Academy of Sciences of the United States of America 2013
-
-
Farrow, M.A.1
Chumbler, N.M.2
Lapierre, L.A.3
Franklin, J.L.4
Rutherford, S.A.5
Goldenring, J.R.6
Lacy, D.B.7
-
128
-
-
26944469989
-
Variability of Clostridium difficile surface proteins and specific serum antibody response in patients with Clostridium difficile-associated disease
-
PMID:16207956
-
Péchiné S, Janoir C, Collignon A. Variability of Clostridium difficile surface proteins and specific serum antibody response in patients with Clostridium difficile-associated disease. J Clin Microbiol 2005; 43:5018-25; PMID:16207956; http://dx.doi.org/10.1128/JCM.43.10.5018-5025.2005
-
(2005)
J Clin Microbiol
, vol.43
, pp. 5018-5025
-
-
Péchiné, S.1
Janoir, C.2
Collignon, A.3
-
129
-
-
15544386802
-
Immunological properties of surface proteins of Clostridium difficile
-
PMID:15673516
-
Péchiné S, Gleizes A, Janoir C, Gorges-Kergot R, Barc MC, Delmée M, Collignon A. Immunological properties of surface proteins of Clostridium difficile. J Med Microbiol 2005; 54:193-6; PMID:15673516; http://dx.doi.org/10.1099/jmm.0.45800-0
-
(2005)
J Med Microbiol
, vol.54
, pp. 193-196
-
-
Péchiné, S.1
Gleizes, A.2
Janoir, C.3
Gorges-Kergot, R.4
Barc, M.C.5
Delmée, M.6
Collignon, A.7
-
130
-
-
45249092259
-
Immunoreactive cell wall proteins of Clostridium difficile identified by human sera
-
PMID:18480333
-
Wright A, Drudy D, Kyne L, Brown K, Fairweather NF. Immunoreactive cell wall proteins of Clostridium difficile identified by human sera. J Med Microbiol 2008; 57:750-6; PMID:18480333; http://dx.doi.org/10.1099/jmm.0.47532-0
-
(2008)
J Med Microbiol
, vol.57
, pp. 750-756
-
-
Wright, A.1
Drudy, D.2
Kyne, L.3
Brown, K.4
Fairweather, N.F.5
-
131
-
-
0032574193
-
Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea
-
PMID:9500319
-
Shim JK, Johnson S, Samore MH, Bliss DZ, Gerding DN. Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea. Lancet 1998; 351:633-6; PMID:9500319; http://dx.doi.org/10.1016/ S0140-6736(97)08062-8
-
(1998)
Lancet
, vol.351
, pp. 633-636
-
-
Shim, J.K.1
Johnson, S.2
Samore, M.H.3
Bliss, D.Z.4
Gerding, D.N.5
-
132
-
-
62249099118
-
New trends in Clostridium difficile virulence and pathogenesis
-
PMID:19303565
-
Denève C, Janoir C, Poilane I, Fantinato C, Collignon A. New trends in Clostridium difficile virulence and pathogenesis. Int J Antimicrob Agents 2009; 33(Suppl 1):S24-8; PMID:19303565; http://dx.doi.org/10.1016/S0924- 8579(09)70012-3
-
(2009)
Int J Antimicrob Agents
, vol.33
, Issue.SUPPL. 1
-
-
Denève, C.1
Janoir, C.2
Poilane, I.3
Fantinato, C.4
Collignon, A.5
-
133
-
-
39049167109
-
Active immunization of hamsters against Clostridium difficile infection using surface-layer protein
-
PMID:18093141
-
Ní Eidhin DB, O'Brien JB, McCabe MS, Athié-Morales V, Kelleher DP. Active immunization of hamsters against Clostridium difficile infection using surface-layer protein. FEMS Immunol Med Microbiol 2008; 52:207-18; PMID:18093141; http://dx.doi.org/10.1111/j.1574-695X.2007.00363.x
-
(2008)
FEMS Immunol Med Microbiol
, vol.52
, pp. 207-218
-
-
Ní Eidhin, D.B.1
O'Brien, J.B.2
McCabe, M.S.3
Athié-Morales, V.4
Kelleher, D.P.5
-
134
-
-
34247178951
-
Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile
-
PMID:17433506
-
Péchiné S, Janoir C, Boureau H, Gleizes A, Tsapis N, Hoys S, Fattal E, Collignon A. Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile. Vaccine 2007; 25:3946-54; PMID:17433506; http://dx.doi.org/10.1016/j.vaccine.2007.02.055
-
(2007)
Vaccine
, vol.25
, pp. 3946-3954
-
-
Péchiné, S.1
Janoir, C.2
Boureau, H.3
Gleizes, A.4
Tsapis, N.5
Hoys, S.6
Fattal, E.7
Collignon, A.8
-
135
-
-
80052576075
-
Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen
-
PMID:21707776
-
Péchiné S, Denève C, Le Monnier A, Hoys S, Janoir C, Collignon A. Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen. FEMS Immunol Med Microbiol 2011; 63:73-81; PMID:21707776; http://dx.doi.org/10.1111/j.1574-695X.2011.00832.x
-
(2011)
FEMS Immunol Med Microbiol
, vol.63
, pp. 73-81
-
-
Péchiné, S.1
Denève, C.2
Le Monnier, A.3
Hoys, S.4
Janoir, C.5
Collignon, A.6
-
136
-
-
80053991733
-
Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile
-
PMID:21664462
-
Sandolo C, Péchiné S, Le Monnier A, Hoys S, Janoir C, Coviello T, Alhaique F, Collignon A, Fattal E, Tsapis N. Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile. Eur J Pharm Biopharm 2011; 79:566-73; PMID:21664462; http://dx.doi.org/10.1016/j.ejpb. 2011.05.011
-
(2011)
Eur J Pharm Biopharm
, vol.79
, pp. 566-573
-
-
Sandolo, C.1
Péchiné, S.2
Le Monnier, A.3
Hoys, S.4
Janoir, C.5
Coviello, T.6
Alhaique, F.7
Collignon, A.8
Fattal, E.9
Tsapis, N.10
-
137
-
-
84882791693
-
Recent mechanistic insights on glycoconjugate vaccines and future perspectives
-
PMID:23841819
-
Berti F, Adamo R. Recent mechanistic insights on glycoconjugate vaccines and future perspectives. ACS Chem Biol 2013; 8:1653-63; PMID:23841819; http://dx.doi.org/10.1021/cb400423g
-
(2013)
ACS Chem Biol
, vol.8
, pp. 1653-1663
-
-
Berti, F.1
Adamo, R.2
-
138
-
-
84875960833
-
Carbohydrate-based Clostridium difficile vaccines
-
PMID:23560922
-
Monteiro MA, Ma Z, Bertolo L, Jiao Y, Arroyo L, Hodgins D, Mallozzi M, Vedantam G, Sagermann M, Sundsmo J, et al. Carbohydrate-based Clostridium difficile vaccines. Expert Rev Vaccines 2013; 12:421-31; PMID:23560922; http://dx.doi.org/10.1586/erv.13.9
-
(2013)
Expert Rev Vaccines
, vol.12
, pp. 421-431
-
-
Monteiro, M.A.1
Ma, Z.2
Bertolo, L.3
Jiao, Y.4
Arroyo, L.5
Hodgins, D.6
Mallozzi, M.7
Vedantam, G.8
Sagermann, M.9
Sundsmo, J.10
-
139
-
-
84865275168
-
Phosphorylation of the synthetic hexasaccharide repeating unit is essential for the induction of antibodies to Clostridium difficile PSII cell wall polysaccharide
-
PMID:22620974
-
Adamo R, Romano MR, Berti F, Leuzzi R, Tontini M, Danieli E, Cappelletti E, Cakici OS, Swennen E, Pinto V, et al. Phosphorylation of the synthetic hexasaccharide repeating unit is essential for the induction of antibodies to Clostridium difficile PSII cell wall polysaccharide. ACS Chem Biol 2012; 7:1420-8; PMID:22620974; http://dx.doi.org/10.1021/cb300221f
-
(2012)
ACS Chem Biol
, vol.7
, pp. 1420-1428
-
-
Adamo, R.1
Romano, M.R.2
Berti, F.3
Leuzzi, R.4
Tontini, M.5
Danieli, E.6
Cappelletti, E.7
Cakici, O.S.8
Swennen, E.9
Pinto, V.10
-
140
-
-
84861194892
-
Structural characterization of surface glycans from Clostridium difficile
-
PMID:22560631
-
Reid CW, Vinogradov E, Li J, Jarrell HC, Logan SM, Brisson JR. Structural characterization of surface glycans from Clostridium difficile. Carbohydr Res 2012; 354:65-73; PMID:22560631; http://dx.doi.org/10.1016/j.carres.2012.02.002
-
(2012)
Carbohydr Res
, vol.354
, pp. 65-73
-
-
Reid, C.W.1
Vinogradov, E.2
Li, J.3
Jarrell, H.C.4
Logan, S.M.5
Brisson, J.R.6
-
141
-
-
84873037097
-
Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile
-
PMID:23175653
-
Crossed D signapa T, Leuzzi R, Ng YK, Baban ST, Adamo R, Kuehne SA, Scarselli M, Minton NP, Serruto D, Unnikrishnan M. Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile. J Bacteriol 2013; 195:545-55; PMID:23175653; http://dx.doi.org/10.1128/JB.01980-12
-
(2013)
J Bacteriol
, vol.195
, pp. 545-555
-
-
Dapa, T.1
Leuzzi, R.2
Ng, Y.K.3
Baban, S.T.4
Adamo, R.5
Kuehne, S.A.6
Scarselli, M.7
Minton, N.P.8
Serruto, D.9
Unnikrishnan, M.10
-
142
-
-
79957532830
-
A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic
-
PMID:21609839
-
Oberli MA, Hecht ML, Bindschädler P, Adibekian A, Adam T, Seeberger PH. A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic. Chem Biol 2011; 18:580-8; PMID:21609839; http://dx.doi.org/10.1016/j.chembiol.2011.03.009
-
(2011)
Chem Biol
, vol.18
, pp. 580-588
-
-
Oberli, M.A.1
Hecht, M.L.2
Bindschädler, P.3
Adibekian, A.4
Adam, T.5
Seeberger, P.H.6
-
143
-
-
84861182186
-
Clostridium difficile carbohydrates: Glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine
-
PMID:22533919
-
Bertolo L, Boncheff AG, Ma Z, Chen YH, Wakeford T, Friendship RM, Rosseau J, Weese JS, Chu M, Mallozzi M, et al. Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine. Carbohydr Res 2012; 354:79-86; PMID:22533919; http://dx.doi.org/10.1016/j.carres.2012.03.032
-
(2012)
Carbohydr Res
, vol.354
, pp. 79-86
-
-
Bertolo, L.1
Boncheff, A.G.2
Ma, Z.3
Chen, Y.H.4
Wakeford, T.5
Friendship, R.M.6
Rosseau, J.7
Weese, J.S.8
Chu, M.9
Mallozzi, M.10
-
144
-
-
39649116922
-
Clostridium difficile cell-surface polysaccharides composed of pentaglycosyl and hexaglycosyl phosphate repeating units
-
PMID:18237724
-
Ganeshapillai J, Vinogradov E, Rousseau J, Weese JS, Monteiro MA. Clostridium difficile cell-surface polysaccharides composed of pentaglycosyl and hexaglycosyl phosphate repeating units. Carbohydr Res 2008; 343:703-10; PMID:18237724; http://dx.doi.org/10.1016/j.carres.2008.01.002
-
(2008)
Carbohydr Res
, vol.343
, pp. 703-710
-
-
Ganeshapillai, J.1
Vinogradov, E.2
Rousseau, J.3
Weese, J.S.4
Monteiro, M.A.5
-
145
-
-
84879776854
-
Immunological evaluation of a synthetic Clostridium difficile oligosaccharide conjugate vaccine candidate and identification of a minimal epitope
-
PMID:23795894
-
Martin CE, Broecker F, Oberli MA, Komor J, Mattner J, Anish C, Seeberger PH. Immunological evaluation of a synthetic Clostridium difficile oligosaccharide conjugate vaccine candidate and identification of a minimal epitope. J Am Chem Soc 2013; 135:9713-22; PMID:23795894; http://dx.doi.org/10. 1021/ja401410y
-
(2013)
J Am Chem Soc
, vol.135
, pp. 9713-9722
-
-
Martin, C.E.1
Broecker, F.2
Oberli, M.A.3
Komor, J.4
Mattner, J.5
Anish, C.6
Seeberger, P.H.7
-
146
-
-
84885020626
-
Clostridium difficile PSI polysaccharide: Synthesis of pentasaccharide repeating block, conjugation to exotoxin B subunit, and detection of natural anti-PSI IgG antibodies in horse serum
-
PMID:23597587
-
Jiao Y, Ma Z, Hodgins D, Pequegnat B, Bertolo L, Arroyo L, Monteiro MA. Clostridium difficile PSI polysaccharide: synthesis of pentasaccharide repeating block, conjugation to exotoxin B subunit, and detection of natural anti-PSI IgG antibodies in horse serum. Carbohydr Res 2013; 378:15-25; PMID:23597587; http://dx.doi.org/10.1016/j.carres.2013.03.018
-
(2013)
Carbohydr Res
, vol.378
, pp. 15-25
-
-
Jiao, Y.1
Ma, Z.2
Hodgins, D.3
Pequegnat, B.4
Bertolo, L.5
Arroyo, L.6
Monteiro, M.A.7
-
147
-
-
84880347916
-
Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine
-
PMID:23836132
-
Martin CE, Broecker F, Eller S, Oberli MA, Anish C, Pereira CL, Seeberger PH. Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine. Chem Commun (Camb) 2013; 49:7159-61; PMID:23836132; http://dx.doi.org/10.1039/c3cc43545h
-
(2013)
Chem Commun (Camb)
, vol.49
, pp. 7159-7161
-
-
Martin, C.E.1
Broecker, F.2
Eller, S.3
Oberli, M.A.4
Anish, C.5
Pereira, C.L.6
Seeberger, P.H.7
-
148
-
-
84887990533
-
Investigating the candidacy of a lipoteichoic acid-based glycoconjugate as a vaccine to combat Clostridium difficile infection
-
PMID:23974722
-
Cox AD, St Michael F, Aubry A, Cairns CM, Strong PC, Hayes AC, Logan SM. Investigating the candidacy of a lipoteichoic acid-based glycoconjugate as a vaccine to combat Clostridium difficile infection. Glycoconj J 2013; 30:843-55; PMID:23974722; http://dx.doi.org/10.1007/s10719-013-9489-3
-
(2013)
Glycoconj J
, vol.30
, pp. 843-855
-
-
Cox, A.D.1
St Michael, F.2
Aubry, A.3
Cairns, C.M.4
Strong, P.C.5
Hayes, A.C.6
Logan, S.M.7
-
149
-
-
84867395811
-
Vaccines for the elderly
-
PMID:22862783
-
Weinberger B, Grubeck-Loebenstein B. Vaccines for the elderly. Clin Microbiol Infect 2012; 18(Suppl 5):100-8; PMID:22862783; http://dx.doi.org/10. 1111/j.1469-0691.2012.03944.x
-
(2012)
Clin Microbiol Infect
, vol.18
, Issue.SUPPL. 5
, pp. 100-108
-
-
Weinberger, B.1
Grubeck-Loebenstein, B.2
-
150
-
-
80051952629
-
Contribution of a government target to controlling Clostridium difficile in the NHS in England
-
PMID:21182972
-
Duerden BI. Contribution of a government target to controlling Clostridium difficile in the NHS in England. Anaerobe 2011; 17:175-9; PMID:21182972; http://dx.doi.org/10.1016/j.anaerobe.2010.12.004
-
(2011)
Anaerobe
, vol.17
, pp. 175-179
-
-
Duerden, B.I.1
-
151
-
-
84864475433
-
Reduction in Clostridium difficile infection rates after mandatory hospital public reporting: Findings from a longitudinal cohort study in Canada
-
PMID:22815656
-
Daneman N, Stukel TA, Ma X, Vermeulen M, Guttmann A. Reduction in Clostridium difficile infection rates after mandatory hospital public reporting: findings from a longitudinal cohort study in Canada. PLoS Med 2012; 9:e1001268; PMID:22815656; http://dx.doi.org/10.1371/journal.pmed.1001268
-
(2012)
PLoS Med
, vol.9
-
-
Daneman, N.1
Stukel, T.A.2
Ma, X.3
Vermeulen, M.4
Guttmann, A.5
-
152
-
-
84862605837
-
Clostridium difficile infection in the community: A zoonotic disease?
-
European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) PMID:22536816
-
Hensgens MP, Keessen EC, Squire MM, Riley TV, Koene MG, de Boer E, Lipman LJ, Kuijper EJ; European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD). Clostridium difficile infection in the community: a zoonotic disease? Clin Microbiol Infect 2012; 18:635-45; PMID:22536816; http://dx.doi.org/10.1111/j.1469-0691.2012.03853.x
-
(2012)
Clin Microbiol Infect
, vol.18
, pp. 635-645
-
-
Hensgens, M.P.1
Keessen, E.C.2
Squire, M.M.3
Riley, T.V.4
Koene, M.G.5
De Boer, E.6
Lipman, L.J.7
Kuijper, E.J.8
-
153
-
-
77952498572
-
Disease transmission model for community-associated Clostridium difficile infection
-
PMID:20092667
-
Otten AM, Reid-Smith RJ, Fazil A, Weese JS. Disease transmission model for community-associated Clostridium difficile infection. Epidemiol Infect 2010; 138:907-14; PMID:20092667; http://dx.doi.org/10.1017/S0950268809991646
-
(2010)
Epidemiol Infect
, vol.138
, pp. 907-914
-
-
Otten, A.M.1
Reid-Smith, R.J.2
Fazil, A.3
Weese, J.S.4
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