Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 79, Issue 3, 2011, Pages 566-573

  Sandolo, Chiara ^a,b,c   Péchiné, Séverine ^d   Le Monnier, Alban ^d   Hoys, Sandra ^d   Janoir, Claire ^d   Coviello, Tommasina ^c   Alhaique, Franco ^c   Collignon, Anne ^d   Fattal, Elias ^a,b   Tsapis, Nicolas ^a,b  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d University Paris Sud   (France)

Author keywords

Clostridium difficile; Colon delivery; Cwp84; Pectin; Vaccination

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL VACCINE; CLINDAMYCIN PHOSPHATE; PECTIN; RECOMBINANT PROTEIN CWP84; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BACTERIAL STRAIN; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; COLON; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; ENCAPSULATION; ENZYME ACTIVITY; FEMALE; IMMUNOGENICITY; NONHUMAN; VACCINATION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; CHEMISTRY, PHARMACEUTICAL; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; CRICETINAE; CYSTEINE ENDOPEPTIDASES; DISEASE MODELS, ANIMAL; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOGLOBULIN G; MOLECULAR WEIGHT; PECTINS; SURVIVAL ANALYSIS;

EID: 80053991733     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.05.011     Document Type: Article

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