Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea

Lancet

Volumn 357, Issue 9251, 2001, Pages 189-193

  Kyne, Lorraine ^a   Warny, Michel ^a   Qamar, Amir ^a   Kelly, Ciarán P ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; IMMUNOGLOBULIN G;

ADULT; ANTIBODY RESPONSE; ARTICLE; CLOSTRIDIUM DIFFICILE; DIARRHEA; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITAL INFECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECURRENCE RISK;

EID: 0035915688     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)03592-3     Document Type: Article

References (28)

1. Clostridium difficile colitis
2. Pathogenesis of Clostridium difficile-associated diarrhoea
3. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
4. Nosocomial acquisition of Clostridium difficile infection
5. Clostridium difficile colonization and diarrhea at a tertiary care hospital
6. Incidence and impact of Clostridium difficile infection in the UK, 1993-1996
7. Clostridium difficile-associated disease in long-term care facilities
8. Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis
9. Treatment of Clostridium difficile infection
10. Recurrent Clostridium difficile disease: Epidemiology and clinical characteristics
11. Recurrent Clostridium difficile diarrhea: Characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial
12. Ten years of prospective Clostridium difficile-associated disease surveillance at the Minneapolis VA Medical Center, 1982-1991
13. Risk factors for early recurrent Clostridium difficile-associated diarrhea
14. Clostridium difficile colitis: Factors influencing treatment failure and relapse - A prospective evaluation
15. Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin
16. Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection
17. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
18. Measuring severity of illness: Homogeneous case mix groups
19. Assessing illness severity: Does clinical judgment work?
20. Purification and characterization of toxins A and B of Clostridium difficile
21. Purificaton of two high molecular weight toxins of Clostridium difficile which are antigenically related
22. Human colonic aspirates containing immunoglobulin A antibody to Clostridium difficile toxin A inhibit toxin A-receptor binding
23. Immunoglobulin G directed against toxins A and B of Clostridium difficile in the general population and patients with antibiotic-associated diarrhea
24. Serum antibody response to Clostridium difficile toxins in patients with Clostridium difficile diarrhoea
25. Systemic and mucosal antibody responses to toxin A in patients infected with Clostridium difficile
26. Immune response to Clostridium difficile infection
27. Prospects for a vaccine for Clostridium difficile