Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: The case for pantothenamides

Biochemical Society Transactions

Volumn 42, Issue 4, 2014, Pages 1087-1093

  Saliba, Kevin J ^a,b   Spry, Christina ^a,c  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b Canberra Hospital   (Australia)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Coenzyme A (CoA); Malaria; Pantetheinase; Pantothenamide; Pantothenate; Plasmodium

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; COENZYME A; PANTOTHENAMIDE DERIVATIVE; PANTOTHENIC ACID DERIVATIVE; PYRIMETHAMINE PLUS SULFADOXINE; UNCLASSIFIED DRUG; AMIDASE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; PANTETHEINASE; PANTOTHENIC ACID;

ANTIBACTERIAL ACTIVITY; ANTIMALARIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; BACTERIAL GROWTH; BIOSYNTHESIS; CONFERENCE PAPER; DRUG DEGRADATION; DRUG IDENTIFICATION; DRUG MECHANISM; ENZYME SYNTHESIS; FATTY ACID SYNTHESIS; HUMAN; HYDROLYSIS; MALARIA; NONHUMAN; PLASMODIUM GALLINACEUM; PRIORITY JOURNAL; ANIMAL; DRUG EFFECTS; METABOLISM; PLASMODIUM FALCIPARUM;

AMIDOHYDROLASES; ANIMALS; ANTIMALARIALS; COENZYME A; GPI-LINKED PROTEINS; HUMANS; MALARIA; PANTOTHENIC ACID; PLASMODIUM FALCIPARUM;

EID: 84905819435     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20140158     Document Type: Conference Paper

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