Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 22, 2008, Pages 5991-5994

  Mercer, Andrew C ^a   Meier, Jordan L ^a   Hur, Gene H ^a   Smith, Andrew R ^a   Burkart, Michael D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antibiotic; Coenzyme A; Fatty acid; Pantothenamides; Structure activity relationships

Indexed keywords

ALKYNYL GROUP; AMIDE; ANTIBIOTIC AGENT; ANTIMETABOLITE; CARRIER PROTEIN; COENZYME A; PANTETHEINE; PANTOTHENIC ACID DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ALDEHYDE-LYASES; ANTI-BACTERIAL AGENTS; ANTIMETABOLITES; COENZYME A; COMBINATORIAL CHEMISTRY TECHNIQUES; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; MOLECULAR STRUCTURE; PANTETHEINE; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 55249093843     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.07.078     Document Type: Article

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