메뉴 건너뛰기




Volumn 1846, Issue 1, 2014, Pages 226-231

Viral infection-oxidative stress/DNA damage-aberrant DNA methylation: Separate or interrelated events responsible for genetic instability and childhood ALL development?

Author keywords

5 Methylcytosine; Acute lymphoblastic leukemia; Deaminases; Epigenetics; Oxidative stress; Viral infection

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE; APOLIPOPROTEIN B MRNA EDITING ENZYME CATALYTIC POLYPEPTIDE LIKE DEAMINASE; CYTOSINE DEAMINASE; DEAMINASE; DNA; UNCLASSIFIED DRUG;

EID: 84905234707     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2014.06.004     Document Type: Review
Times cited : (9)

References (61)
  • 1
    • 0032572912 scopus 로고    scopus 로고
    • Acute lymphoblastic leukemia
    • Pui C.H., Evans W.E. Acute lymphoblastic leukemia. N. Engl. J. Med. 1998, 339:605-615.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 605-615
    • Pui, C.H.1    Evans, W.E.2
  • 2
    • 84555202748 scopus 로고    scopus 로고
    • Biology, risk stratification, and therapy of pediatric acute leukemias: an update (vol 29, pg 551, 2011)
    • Pui C.H., Carroll W.L., Meshinchi S. Biology, risk stratification, and therapy of pediatric acute leukemias: an update (vol 29, pg 551, 2011). J. Clin. Oncol. 2011, 29:4847.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 4847
    • Pui, C.H.1    Carroll, W.L.2    Meshinchi, S.3
  • 3
    • 70349833393 scopus 로고    scopus 로고
    • Cytogenetics and molecular genetics of acute lymphoblastic leukemia
    • Mrozek K., Harper D.P., Aplan P.D. Cytogenetics and molecular genetics of acute lymphoblastic leukemia. Hematol. Oncol. Clin. North Am. 2009, 23:991-1010.
    • (2009) Hematol. Oncol. Clin. North Am. , vol.23 , pp. 991-1010
    • Mrozek, K.1    Harper, D.P.2    Aplan, P.D.3
  • 4
    • 33644545382 scopus 로고    scopus 로고
    • Infection, immune responses and the aetiology of childhood leukaemia
    • Greaves M. Infection, immune responses and the aetiology of childhood leukaemia. Nat. Rev. Cancer 2006, 6:193-203.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 193-203
    • Greaves, M.1
  • 5
    • 0024204062 scopus 로고
    • Evidence for an infective cause of childhood leukemia - comparison of a Scottish New Town with nuclear reprocessing sites in Britain
    • Kinlen L. Evidence for an infective cause of childhood leukemia - comparison of a Scottish New Town with nuclear reprocessing sites in Britain. Lancet 1988, 2:1323-1327.
    • (1988) Lancet , vol.2 , pp. 1323-1327
    • Kinlen, L.1
  • 6
    • 0023857908 scopus 로고
    • Speculations on the cause of childhood acute lymphoblastic-leukemia
    • Greaves M.F. Speculations on the cause of childhood acute lymphoblastic-leukemia. Leukemia 1988, 2:120-125.
    • (1988) Leukemia , vol.2 , pp. 120-125
    • Greaves, M.F.1
  • 7
    • 33847363217 scopus 로고    scopus 로고
    • Childhood acute lymphoblastic leukemia and infections in the first year of life: a report from the United Kingdom Childhood Cancer Study
    • Roman E., Simpson J., Ansell P., Kinsey S., Mitchell C.D., McKinney P.A., et al. Childhood acute lymphoblastic leukemia and infections in the first year of life: a report from the United Kingdom Childhood Cancer Study. Am. J. Epidemiol. 2007, 165:496-504.
    • (2007) Am. J. Epidemiol. , vol.165 , pp. 496-504
    • Roman, E.1    Simpson, J.2    Ansell, P.3    Kinsey, S.4    Mitchell, C.D.5    McKinney, P.A.6
  • 8
    • 0028980161 scopus 로고
    • DNA-damage and cancer - measurement and mechanism
    • Wiseman H., Kaur H., Halliwell B. DNA-damage and cancer - measurement and mechanism. Cancer Lett. 1995, 93:113-120.
    • (1995) Cancer Lett. , vol.93 , pp. 113-120
    • Wiseman, H.1    Kaur, H.2    Halliwell, B.3
  • 9
    • 32044466239 scopus 로고    scopus 로고
    • Does measurement of oxidative damage to DNA have clinical significance?
    • Cooke M.S., Olinski R., Evans M.D. Does measurement of oxidative damage to DNA have clinical significance?. Clin. Chim. Acta 2006, 365:30-49.
    • (2006) Clin. Chim. Acta , vol.365 , pp. 30-49
    • Cooke, M.S.1    Olinski, R.2    Evans, M.D.3
  • 11
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher P., Beckman J.S., Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 2007, 87:315-424.
    • (2007) Physiol. Rev. , vol.87 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 12
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 16
    • 84940106932 scopus 로고    scopus 로고
    • DNA repair gene polymorphisms and their relation with DNA damage, DNA repair, and total antioxidant capacity in childhood acute lymphoblastic leukemia survivors
    • Dincer Y., Yuksel S., Batar B., Guven M., Onaran I., Celkan T. DNA repair gene polymorphisms and their relation with DNA damage, DNA repair, and total antioxidant capacity in childhood acute lymphoblastic leukemia survivors. J. Pediatr. Hematol. Oncol. 2014, 10.1097/MPH.0000000000000133.
    • (2014) J. Pediatr. Hematol. Oncol.
    • Dincer, Y.1    Yuksel, S.2    Batar, B.3    Guven, M.4    Onaran, I.5    Celkan, T.6
  • 17
    • 70249120673 scopus 로고    scopus 로고
    • Determinants of urinary 8-hydroxy-2'-deoxyguanosine in Chinese children with acute leukemia
    • Yang Y., Tian Y., Yan C., Jin X., Tang J., Shen X. Determinants of urinary 8-hydroxy-2'-deoxyguanosine in Chinese children with acute leukemia. Environ. Toxicol. 2009, 24:446-452.
    • (2009) Environ. Toxicol. , vol.24 , pp. 446-452
    • Yang, Y.1    Tian, Y.2    Yan, C.3    Jin, X.4    Tang, J.5    Shen, X.6
  • 18
    • 78651073009 scopus 로고    scopus 로고
    • The association of polymorphisms in DNA base excision repair genes XRCC1, OGG1 and MUTYH with the risk of childhood acute lymphoblastic leukemia
    • Stanczyk M., Sliwinski T., Cuchra M., Zubowska M., Bielecka-Kowalska A., Kowalski M., et al. The association of polymorphisms in DNA base excision repair genes XRCC1, OGG1 and MUTYH with the risk of childhood acute lymphoblastic leukemia. Mol. Biol. Rep. 2011, 38:445-451.
    • (2011) Mol. Biol. Rep. , vol.38 , pp. 445-451
    • Stanczyk, M.1    Sliwinski, T.2    Cuchra, M.3    Zubowska, M.4    Bielecka-Kowalska, A.5    Kowalski, M.6
  • 19
    • 34548363273 scopus 로고    scopus 로고
    • Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns
    • Dziaman T., Gackowski D., Rozalski R., Siomek A., Szulczynski J., Zabielski R., et al. Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns. Free Radic. Res. 2007, 41:997-1004.
    • (2007) Free Radic. Res. , vol.41 , pp. 997-1004
    • Dziaman, T.1    Gackowski, D.2    Rozalski, R.3    Siomek, A.4    Szulczynski, J.5    Zabielski, R.6
  • 21
    • 33745125112 scopus 로고    scopus 로고
    • Promoter hypermethylation and global hypomethylation are independent epigenetic events in lymphoid leukemogenesis with opposing effects on clinical outcome
    • Roman-Gomez J., Jimenez-Velasco A., Agirre X., Castillejo J.A., Navarro G., Garate L., et al. Promoter hypermethylation and global hypomethylation are independent epigenetic events in lymphoid leukemogenesis with opposing effects on clinical outcome. Leukemia 2006, 20:1445-1448.
    • (2006) Leukemia , vol.20 , pp. 1445-1448
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3    Castillejo, J.A.4    Navarro, G.5    Garate, L.6
  • 22
    • 84861939584 scopus 로고    scopus 로고
    • A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia
    • Wong N.C., Ashley D., Chatterton Z., Parkinson-Bates M., Ng H.K., Halemba M.S., et al. A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia. Epigenetics 2012, 7:535-541.
    • (2012) Epigenetics , vol.7 , pp. 535-541
    • Wong, N.C.1    Ashley, D.2    Chatterton, Z.3    Parkinson-Bates, M.4    Ng, H.K.5    Halemba, M.S.6
  • 23
    • 84859516017 scopus 로고    scopus 로고
    • DNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission
    • Nordlund J., Milani L., Lundmark A., Lonnerholm G., Syvanen A.C. DNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission. PLoS One 2012, 7:e34513.
    • (2012) PLoS One , vol.7
    • Nordlund, J.1    Milani, L.2    Lundmark, A.3    Lonnerholm, G.4    Syvanen, A.C.5
  • 26
    • 61449111951 scopus 로고    scopus 로고
    • Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation
    • Milani L., Lundmark A., Nordlund J., Kiialainen A., Flaegstad T., Jonmundsson G., et al. Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation. Genome Res. 2009, 19:1-11.
    • (2009) Genome Res. , vol.19 , pp. 1-11
    • Milani, L.1    Lundmark, A.2    Nordlund, J.3    Kiialainen, A.4    Flaegstad, T.5    Jonmundsson, G.6
  • 27
    • 67349200930 scopus 로고    scopus 로고
    • The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells
    • Flotho C., Claus R., Batz C., Schneider M., Sandrock I., Ihde S., Plass C., Niemeyer C.M., Lubbert M. The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia 2009, 23:1019-1028.
    • (2009) Leukemia , vol.23 , pp. 1019-1028
    • Flotho, C.1    Claus, R.2    Batz, C.3    Schneider, M.4    Sandrock, I.5    Ihde, S.6    Plass, C.7    Niemeyer, C.M.8    Lubbert, M.9
  • 28
    • 84886860116 scopus 로고    scopus 로고
    • TET enzymes, TDG and the dynamics of DNA demethylation
    • Kohli R.M., Zhang Y. TET enzymes, TDG and the dynamics of DNA demethylation. Nature 2013, 502:472-479.
    • (2013) Nature , vol.502 , pp. 472-479
    • Kohli, R.M.1    Zhang, Y.2
  • 29
    • 84884590688 scopus 로고    scopus 로고
    • Potential functional roles of DNA demethylation intermediates
    • Song C.X., He C. Potential functional roles of DNA demethylation intermediates. Trends Biochem. Sci. 2013, 38:480-484.
    • (2013) Trends Biochem. Sci. , vol.38 , pp. 480-484
    • Song, C.X.1    He, C.2
  • 30
    • 0037350661 scopus 로고    scopus 로고
    • TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
    • Lorsbach R.B., Moore J., Mathew S., Raimondi S.C., Mukatira S.T., Downing J.R. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 2003, 17:637-641.
    • (2003) Leukemia , vol.17 , pp. 637-641
    • Lorsbach, R.B.1    Moore, J.2    Mathew, S.3    Raimondi, S.C.4    Mukatira, S.T.5    Downing, J.R.6
  • 31
    • 84895810190 scopus 로고    scopus 로고
    • The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases
    • Solary E., Bernard O.A., Tefferi A., Fuks F., Vainchenker W. The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases. Leukemia 2014, 28:485-496.
    • (2014) Leukemia , vol.28 , pp. 485-496
    • Solary, E.1    Bernard, O.A.2    Tefferi, A.3    Fuks, F.4    Vainchenker, W.5
  • 32
    • 84859229392 scopus 로고    scopus 로고
    • Role of TET2 mutations in myeloproliferative neoplasms
    • Pronier E., Delhommeau F. Role of TET2 mutations in myeloproliferative neoplasms. Curr. Hematol. Malig. Rep. 2012, 7:57-64.
    • (2012) Curr. Hematol. Malig. Rep. , vol.7 , pp. 57-64
    • Pronier, E.1    Delhommeau, F.2
  • 34
    • 79960062301 scopus 로고    scopus 로고
    • TET2 Inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
    • Quivoron C., Couronne L., Della Valle V., Lopez C.K., Plo I., Wagner-Ballon O., et al. TET2 Inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011, 20:25-38.
    • (2011) Cancer Cell , vol.20 , pp. 25-38
    • Quivoron, C.1    Couronne, L.2    Della Valle, V.3    Lopez, C.K.4    Plo, I.5    Wagner-Ballon, O.6
  • 35
    • 79959937861 scopus 로고    scopus 로고
    • Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
    • Cortellino S., Xu J., Sannai M., Moore R., Caretti E., Cigliano A., et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 2011, 146:67-79.
    • (2011) Cell , vol.146 , pp. 67-79
    • Cortellino, S.1    Xu, J.2    Sannai, M.3    Moore, R.4    Caretti, E.5    Cigliano, A.6
  • 36
    • 80052933429 scopus 로고    scopus 로고
    • DNA demethylation dynamics
    • Bhutani N., Burns D.M., Blau H.M. DNA demethylation dynamics. Cell 2011, 146:866-872.
    • (2011) Cell , vol.146 , pp. 866-872
    • Bhutani, N.1    Burns, D.M.2    Blau, H.M.3
  • 38
    • 84856158823 scopus 로고    scopus 로고
    • The curious chemical biology of Cytosine: deamination, methylation, and oxidation as modulators of genomic potential
    • Nabel C.S., Manning S.A., Kohli R.M. The curious chemical biology of Cytosine: deamination, methylation, and oxidation as modulators of genomic potential. ACS Chem. Biol. 2012, 7:20-30.
    • (2012) ACS Chem. Biol. , vol.7 , pp. 20-30
    • Nabel, C.S.1    Manning, S.A.2    Kohli, R.M.3
  • 39
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu M., Sankaranand V.S., Anant S., Sugai M., Kinoshita K., Davidson N.O., et al. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 1999, 274:18470-18476.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18470-18476
    • Muramatsu, M.1    Sankaranand, V.S.2    Anant, S.3    Sugai, M.4    Kinoshita, K.5    Davidson, N.O.6
  • 41
    • 0037108463 scopus 로고    scopus 로고
    • Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
    • Rada C., Williams G.T., Nilsen H., Barnes D.E., Lindahl T., Neuberger M.S. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 2002, 12:1748-1755.
    • (2002) Curr. Biol. , vol.12 , pp. 1748-1755
    • Rada, C.1    Williams, G.T.2    Nilsen, H.3    Barnes, D.E.4    Lindahl, T.5    Neuberger, M.S.6
  • 42
    • 34249790004 scopus 로고    scopus 로고
    • Molecular mechanisms of antibody somatic hypermutation
    • Di Nola J.M., Neuberger M.S. Molecular mechanisms of antibody somatic hypermutation. Ann. Rev. Biochem. 2007, 76:1-22.
    • (2007) Ann. Rev. Biochem. , vol.76 , pp. 1-22
    • Di Nola, J.M.1    Neuberger, M.S.2
  • 44
    • 63149179802 scopus 로고    scopus 로고
    • Balancing AID and DNA repair during somatic hypermutation
    • Liu M., Schatz D.G. Balancing AID and DNA repair during somatic hypermutation. Trends Immunol. 2009, 30:173-181.
    • (2009) Trends Immunol. , vol.30 , pp. 173-181
    • Liu, M.1    Schatz, D.G.2
  • 45
    • 84878341989 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • Inaba H., Greaves M., Mullighan C.G. Acute lymphoblastic leukaemia. Lancet 2013, 381:1943-1955.
    • (2013) Lancet , vol.381 , pp. 1943-1955
    • Inaba, H.1    Greaves, M.2    Mullighan, C.G.3
  • 46
    • 34147180434 scopus 로고    scopus 로고
    • Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
    • Matsumoto Y., Marusawa H., Kinoshita K., Endo Y., Kou T., Morisawa T., et al. Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat. Med. 2007, 13:470-476.
    • (2007) Nat. Med. , vol.13 , pp. 470-476
    • Matsumoto, Y.1    Marusawa, H.2    Kinoshita, K.3    Endo, Y.4    Kou, T.5    Morisawa, T.6
  • 47
    • 0037866404 scopus 로고    scopus 로고
    • Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas
    • Greeve J., Philipsen A., Krause K., Klapper W., Heidorn K., Castle B.E., et al. Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas. Blood 2003, 101:3574-3580.
    • (2003) Blood , vol.101 , pp. 3574-3580
    • Greeve, J.1    Philipsen, A.2    Krause, K.3    Klapper, W.4    Heidorn, K.5    Castle, B.E.6
  • 48
    • 69249236962 scopus 로고    scopus 로고
    • The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia
    • Klemm L., Duy C., Iacobucci I., Kuchen S., von Levetzow G., Feldhahn N., et al. The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. Cancer Cell 2009, 16:232-245.
    • (2009) Cancer Cell , vol.16 , pp. 232-245
    • Klemm, L.1    Duy, C.2    Iacobucci, I.3    Kuchen, S.4    von Levetzow, G.5    Feldhahn, N.6
  • 51
    • 34249015960 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells
    • Feldhahn N., Henke N., Melchior K., Duy C., Soh B.N., Klein F., et al. Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells. J. Exp. Med. 2007, 204:1157-1166.
    • (2007) J. Exp. Med. , vol.204 , pp. 1157-1166
    • Feldhahn, N.1    Henke, N.2    Melchior, K.3    Duy, C.4    Soh, B.N.5    Klein, F.6
  • 52
    • 77957377050 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia
    • Gruber T.A., Chang M.S., Sposto R., Muschen M. Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia. Cancer Res. 2010, 70:7411-7420.
    • (2010) Cancer Res. , vol.70 , pp. 7411-7420
    • Gruber, T.A.1    Chang, M.S.2    Sposto, R.3    Muschen, M.4
  • 53
    • 2142819411 scopus 로고    scopus 로고
    • Mechanisms of disease: acute lymphoblastic leukemia
    • Pui C., Relling M.V., Downing J.R. Mechanisms of disease: acute lymphoblastic leukemia. N. Engl. J. Med. 2004, 350:1535-1548.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1535-1548
    • Pui, C.1    Relling, M.V.2    Downing, J.R.3
  • 54
    • 74249101770 scopus 로고    scopus 로고
    • Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients
    • Iacobucci I., Lonetti A., Messa F., Ferrari A., Cilloni D., Soverini S., et al. Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients. Leukemia 2010, 24:66-73.
    • (2010) Leukemia , vol.24 , pp. 66-73
    • Iacobucci, I.1    Lonetti, A.2    Messa, F.3    Ferrari, A.4    Cilloni, D.5    Soverini, S.6
  • 55
  • 56
    • 84883356320 scopus 로고    scopus 로고
    • Evidence for APOBEC3B mutagenesis in multiple human cancers
    • Burns M.B., Temiz N.A., Harris R.S. Evidence for APOBEC3B mutagenesis in multiple human cancers. Nat. Gen. 2013, 45:977-983.
    • (2013) Nat. Gen. , vol.45 , pp. 977-983
    • Burns, M.B.1    Temiz, N.A.2    Harris, R.S.3
  • 57
    • 57149090084 scopus 로고    scopus 로고
    • Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally
    • Wiemels J.L., Hofmann J., Kang M., Selzer R., Green R., Zhou M., et al. Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally. Cancer Res. 2008, 68:9935-9944.
    • (2008) Cancer Res. , vol.68 , pp. 9935-9944
    • Wiemels, J.L.1    Hofmann, J.2    Kang, M.3    Selzer, R.4    Green, R.5    Zhou, M.6
  • 59
    • 0141482011 scopus 로고    scopus 로고
    • Leukemia in twins: lessons in natural history
    • Greaves M.F., Maia A.T., Wiemels J.L., Ford A.M. Leukemia in twins: lessons in natural history. Blood 2003, 102:2321-2333.
    • (2003) Blood , vol.102 , pp. 2321-2333
    • Greaves, M.F.1    Maia, A.T.2    Wiemels, J.L.3    Ford, A.M.4
  • 60
    • 43749124047 scopus 로고    scopus 로고
    • Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU)
    • Beumer J.H., Parise R.A., Newman E.M., Doroshow J.H., Synold T.W., Lenz H.J., Egorin M.J. Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU). Cancer Chemother. Pharmacol. 2008, 62:363-368.
    • (2008) Cancer Chemother. Pharmacol. , vol.62 , pp. 363-368
    • Beumer, J.H.1    Parise, R.A.2    Newman, E.M.3    Doroshow, J.H.4    Synold, T.W.5    Lenz, H.J.6    Egorin, M.J.7
  • 61
    • 0017866954 scopus 로고
    • Deoxyuridine triphosphatase of Escherichia coli - purification, properties, and use as a reagent to reduce uracil incorporation into DNA
    • Shlomai J., Kornberg A. Deoxyuridine triphosphatase of Escherichia coli - purification, properties, and use as a reagent to reduce uracil incorporation into DNA. J. Biol. Chem. 1978, 253:3305-3312.
    • (1978) J. Biol. Chem. , vol.253 , pp. 3305-3312
    • Shlomai, J.1    Kornberg, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.