Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice

Nutrients

Volumn 6, Issue 8, 2014, Pages 3000-3017

  Marín, Tamara ^a   Contreras, Pablo ^a   Castro, Juan Francisco ^a   Chamorro, David ^a   Balboa, Elisa ^a   Bosch Morató, Mònica ^b   Muñoz, Francisco J ^b   Alvarez, Alejandra R ^a   Zanlungo, Silvana ^a,c  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c Fondap Center of Genome Regulation   (Chile)

Author keywords

Apoptosis; c Abl; Cholesterol; Lysosomes; Niemann Pick C; Vitamin E

Indexed keywords

3 NITROTYROSINE; ABELSON KINASE; ALPHA TOCOPHEROL; CALBINDIN; CASPASE 3; FILIPIN; IMATINIB; PROTEIN P73; 3-NITROTYROSINE; CASP3 PROTEIN, MOUSE; DNA BINDING PROTEIN; NUCLEAR PROTEIN; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; CELL LOSS; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; CULTURE MEDIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LOCOMOTION; MALE; MOUSE; NERVE DEGENERATION; NIEMANN PICK DISEASE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; PURKINJE CELL; VITAMIN SUPPLEMENTATION; WEIGHT REDUCTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; DIET SUPPLEMENTATION; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; LYSOSOME; METABOLISM; NEURODEGENERATIVE DISEASES; NIEMANN-PICK DISEASE, TYPE C; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

ALPHA-TOCOPHEROL; ANIMALS; CASPASE 3; CELL LINE; CELL SURVIVAL; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; LYSOSOMES; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEURODEGENERATIVE DISEASES; NIEMANN-PICK DISEASE, TYPE C; NUCLEAR PROTEINS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-ABL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; TYROSINE; VITAMIN E;

EID: 84905229021     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu6083000     Document Type: Article

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