δ-tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders

Journal of Biological Chemistry

Volumn 287, Issue 47, 2012, Pages 39349-39360

  Xu, Miao ^a,g   Liu, Ke ^a   Swaroop, Manju ^a   Porter, Forbes D ^b   Sidhu, Rohini ^c   Finkes, Sally ^c   Ory, Daniel S ^c   Marugan, Juan J ^a   Xiao, Jingbo ^a   Southall, Noel ^a   Pavan, William J ^d   Davidson, Cristin ^e   Walkley, Steven U ^e   Remaley, Alan T ^f   Baxa, Ulrich ^h   Sun, Wei ^a   McKew, John C ^a   Austin, Christopher P ^a   Zheng, Wei ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^g ZHEJIANG UNIVERSITY   (China)

^h NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR CHOLESTEROL; CEROID LIPOFUSCINOSIS; CHOLESTEROL ACCUMULATION; CHOLESTEROL EFFLUX; GENES ENCODING; INTRACELLULAR CA; LIPID ACCUMULATIONS; STORAGE DISORDERS; THERAPEUTIC TARGETS;

CELL CULTURE; CHOLESTEROL; FIBROBLASTS; PROTEINS;

DIGITAL STORAGE;

CALCIUM ION; CHOLESTEROL; DELTA TOCOPHEROL; LIPID;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL VOLUME; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; EXOCYTOSIS; FIBROBLAST; HUMAN; HUMAN CELL; LIPID STORAGE; LYSOSOME; LYSOSOME STORAGE DISEASE; NIEMANN PICK DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WOLMAN CHOLESTEROL STORAGE DISEASE;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL LINE; CHOLESTEROL; CRICETINAE; EXOCYTOSIS; HUMANS; LIPID METABOLISM; LYSOSOMES; NIEMANN-PICK DISEASE, TYPE C; TOCOPHEROLS; WOLMAN DISEASE;

EID: 84869223163     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.357707     Document Type: Article

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