-
1
-
-
84876665662
-
-
WHO, Fact sheet Ni{dotless}312
-
WHO (2012) Diabetes. Fact sheet Ni{dotless}312.
-
(2012)
Diabetes
-
-
-
2
-
-
77955102082
-
Oral protein therapy for the future-transport of glycolipid-modified proteins: Vision or fiction?
-
Müller G (2010) Oral protein therapy for the future-transport of glycolipid-modified proteins: vision or fiction? Pharmacology 86: 92-116.
-
(2010)
Pharmacology
, vol.86
, pp. 92-116
-
-
Müller, G.1
-
3
-
-
4344640503
-
The physiological rationale for oral insulin administration
-
Arbit E (2004) The physiological rationale for oral insulin administration. Diabetes Technol Ther 6: 510-517.
-
(2004)
Diabetes Technol Ther
, vol.6
, pp. 510-517
-
-
Arbit, E.1
-
4
-
-
0346256860
-
Advances in biomaterials, drug delivery, and bionanotechnology
-
Langer R, Peppas NA (2003) Advances in biomaterials, drug delivery, and bionanotechnology. AIChE J 49: 2990-3006.
-
(2003)
AIChE J
, vol.49
, pp. 2990-3006
-
-
Langer, R.1
Peppas, N.A.2
-
5
-
-
33745674687
-
Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems
-
Pinto Reis C, Neufeld RJ, Ribeiro AJ, Veiga F (2006) Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems. Nanomedicine 2: 53-65.
-
(2006)
Nanomedicine
, vol.2
, pp. 53-65
-
-
Pinto Reis, C.1
Neufeld, R.J.2
Ribeiro, A.J.3
Veiga, F.4
-
6
-
-
75149180515
-
Standards of medical care in diabetes-2010
-
American Diabetes Association
-
American Diabetes Association (2010) Standards of medical care in diabetes-2010. Diabetes Care 33: S11-S61.
-
(2010)
Diabetes Care
, vol.33
-
-
-
7
-
-
47149087514
-
Demonstrating strategies for initiation of insulin therapy: Matching the right insulin to the right patient
-
Meneghini L (2008) Demonstrating strategies for initiation of insulin therapy: matching the right insulin to the right patient. Int J Clin Pract 62: 1255-1264.
-
(2008)
Int J Clin Pract
, vol.62
, pp. 1255-1264
-
-
Meneghini, L.1
-
8
-
-
59949100151
-
Insulin analog therapy: Improving the match with physiologic insulin secretion
-
Freeman JS (2009) Insulin analog therapy: improving the match with physiologic insulin secretion. J Am Osteopath Assoc 109: 26-36.
-
(2009)
J Am Osteopath Assoc
, vol.109
, pp. 26-36
-
-
Freeman, J.S.1
-
9
-
-
0036701596
-
Novel insulins: Expanding options in diabetes management
-
Gerich JE (2002) Novel insulins: expanding options in diabetes management. Am J Med 113: 308-316.
-
(2002)
Am J Med
, vol.113
, pp. 308-316
-
-
Gerich, J.E.1
-
10
-
-
33644616090
-
Alginate microspheres prepared by internal gelation: Development and effect on insulin stability
-
Silva CM, Ribeiro AJ, Figueiredo IV, Goncalves AR, Veiga F (2006) Alginate microspheres prepared by internal gelation: development and effect on insulin stability. Int J Pharm 311: 1-10.
-
(2006)
Int J Pharm
, vol.311
, pp. 1-10
-
-
Silva, C.M.1
Ribeiro, A.J.2
Figueiredo, I.V.3
Goncalves, A.R.4
Veiga, F.5
-
11
-
-
47349128146
-
Superiority of insulin analogues versus human insulin in the treatment of diabetes mellitus
-
Rossetti P, Porcellati F, Fanelli CG, Perriello G, Torlone E, Bolli GB (2008) Superiority of insulin analogues versus human insulin in the treatment of diabetes mellitus. Arch Physiol Biochem 114: 3-10.
-
(2008)
Arch Physiol Biochem
, vol.114
, pp. 3-10
-
-
Rossetti, P.1
Porcellati, F.2
Fanelli, C.G.3
Perriello, G.4
Torlone, E.5
Bolli, G.B.6
-
13
-
-
0034768026
-
Spray-dried insulin particles retain biological activity in rapid in-vitro assay
-
Patel N, Craddock BL, Staniforth JN, Tobyn MJ, Welham MJ (2001) Spray-dried insulin particles retain biological activity in rapid in-vitro assay. J Pharm Pharmacol 53: 1415-1418.
-
(2001)
J Pharm Pharmacol
, vol.53
, pp. 1415-1418
-
-
Patel, N.1
Craddock, B.L.2
Staniforth, J.N.3
Tobyn, M.J.4
Welham, M.J.5
-
14
-
-
0034844734
-
Alternative routes of administration as an approach to improve insulin therapy: Update on dermal, oral, nasal and pulmonary insulin delivery
-
Heinemann L, Pfutzner A, Heise T (2001) Alternative routes of administration as an approach to improve insulin therapy: update on dermal, oral, nasal and pulmonary insulin delivery. Curr Pharm Des 7: 1327-1351.
-
(2001)
Curr Pharm Des
, vol.7
, pp. 1327-1351
-
-
Heinemann, L.1
Pfutzner, A.2
Heise, T.3
-
15
-
-
1542498664
-
Alternative routes of insulin delivery
-
Owens DR, Zinman B, Bolli G (2003) Alternative routes of insulin delivery. Diabet Med 20: 886-898.
-
(2003)
Diabet Med
, vol.20
, pp. 886-898
-
-
Owens, D.R.1
Zinman, B.2
Bolli, G.3
-
16
-
-
39049124118
-
Nanoparticle strategies for the oral delivery of insulin
-
Damge C, Reis CP, Maincent P (2008) Nanoparticle strategies for the oral delivery of insulin. Expert Opin Drug Deliv 5: 45-68.
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 45-68
-
-
Damge, C.1
Reis, C.P.2
Maincent, P.3
-
17
-
-
76749171731
-
Personalized prognosis and diagnosis of type 2 diabetes-vision or fiction?
-
Müller G (2010) Personalized prognosis and diagnosis of type 2 diabetes-vision or fiction? Pharmacology 85: 168-187.
-
(2010)
Pharmacology
, vol.85
, pp. 168-187
-
-
Müller, G.1
-
18
-
-
75149194285
-
Design of oral insulin delivery systems
-
Wong TW (2010) Design of oral insulin delivery systems. J Drug Target 18: 79-92.
-
(2010)
J Drug Target
, vol.18
, pp. 79-92
-
-
Wong, T.W.1
-
21
-
-
28044461993
-
Strategies to improve oral drug bioavailability
-
Gomez-Orellana I (2005) Strategies to improve oral drug bioavailability. Expert Opin Drug Deliv 2: 419-433.
-
(2005)
Expert Opin Drug Deliv
, vol.2
, pp. 419-433
-
-
Gomez-Orellana, I.1
-
22
-
-
0141830659
-
Polymeric nano-and microparticles for the oral delivery of peptides and peptidomimetics
-
Allémann E, Leroux J, Gurny R (1998) Polymeric nano-and microparticles for the oral delivery of peptides and peptidomimetics. Adv Drug Deliv Rev 34: 171-189.
-
(1998)
Adv Drug Deliv Rev
, vol.34
, pp. 171-189
-
-
Allémann, E.1
Leroux, J.2
Gurny, R.3
-
23
-
-
0032402219
-
Evaluation of nano-and microparticle uptake by the gastrointestinal tract
-
Delie F (1998) Evaluation of nano-and microparticle uptake by the gastrointestinal tract. Adv Drug Deliv Rev 34: 221-233.
-
(1998)
Adv Drug Deliv Rev
, vol.34
, pp. 221-233
-
-
Delie, F.1
-
24
-
-
43249085343
-
Mucoadhesion and the gastrointestinal tract
-
Varum FJ, McConnell EL, Sousa JJ, Veiga F, Basit AW (2008) Mucoadhesion and the gastrointestinal tract. Crit Rev Ther Drug Carrier Syst 25: 207-258.
-
(2008)
Crit Rev Ther Drug Carrier Syst
, vol.25
, pp. 207-258
-
-
Varum, F.J.1
McConnell, E.L.2
Sousa, J.J.3
Veiga, F.4
Basit, A.W.5
-
25
-
-
44249095621
-
Developments in polymeric devices for oral insulin delivery
-
Babu VR, Patel P, Mundargi RC, Rangaswamy V, Aminabhavi TM (2008) Developments in polymeric devices for oral insulin delivery. Expert Opin Drug Deliv 5: 403-415.
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 403-415
-
-
Babu, V.R.1
Patel, P.2
Mundargi, R.C.3
Rangaswamy, V.4
Aminabhavi, T.M.5
-
27
-
-
73549111762
-
Challenges and advances in nanoparticle-based oral insulin delivery
-
Ramesan RM, Sharma CP (2009) Challenges and advances in nanoparticle-based oral insulin delivery. Expert Rev Med Devices 6: 665-676.
-
(2009)
Expert Rev Med Devices
, vol.6
, pp. 665-676
-
-
Ramesan, R.M.1
Sharma, C.P.2
-
28
-
-
47049095564
-
Strategies toward the improved oral delivery of insulin nanoparticles via gastrointestinal uptake and translocation
-
Woitiski CB, Carvalho RA, Ribeiro AJ, Neufeld RJ, Veiga F (2008) Strategies toward the improved oral delivery of insulin nanoparticles via gastrointestinal uptake and translocation. BioDrugs 22: 223-237.
-
(2008)
BioDrugs
, vol.22
, pp. 223-237
-
-
Woitiski, C.B.1
Carvalho, R.A.2
Ribeiro, A.J.3
Neufeld, R.J.4
Veiga, F.5
-
29
-
-
80054061227
-
A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery
-
Chen MC, Sonaje K, Chen KJ, Sung HW (2011) A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery. Biomaterials 32: 9826-9838.
-
(2011)
Biomaterials
, vol.32
, pp. 9826-9838
-
-
Chen, M.C.1
Sonaje, K.2
Chen, K.J.3
Sung, H.W.4
-
30
-
-
60149111908
-
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
-
Lai SK, Wang Y-Y, Hanes J (2009) Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv Drug Deliv Rev 61: 158-171.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 158-171
-
-
Lai, S.K.1
Wang, Y.-Y.2
Hanes, J.3
-
31
-
-
0023578342
-
Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine
-
Aprahamian M, Michel C, Humbert W, Devissaguet JP, Damge C (1987) Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine. Biol Cell 61: 69-76.
-
(1987)
Biol Cell
, vol.61
, pp. 69-76
-
-
Aprahamian, M.1
Michel, C.2
Humbert, W.3
Devissaguet, J.P.4
Damge, C.5
-
32
-
-
0025069886
-
Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches
-
Eldridge JH, Hammond CJ, Meulbroek JA, Staas JK, Gilley RM, Tice TR (1990) Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches. J Control Release 11: 205-214.
-
(1990)
J Control Release
, vol.11
, pp. 205-214
-
-
Eldridge, J.H.1
Hammond, C.J.2
Meulbroek, J.A.3
Staas, J.K.4
Gilley, R.M.5
Tice, T.R.6
-
33
-
-
68949208465
-
Nanocarriers' entry into the cell: Relevance to drug delivery
-
Hillaireau H, Couvreur P (2009) Nanocarriers' entry into the cell: relevance to drug delivery. Cell Mol Life Sci 66: 2873-2896.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2873-2896
-
-
Hillaireau, H.1
Couvreur, P.2
-
34
-
-
0030471901
-
Gastrointestinal uptake of biodegradable microparticles: Effect of particle size
-
Desai MP, Labhasetwar V, Amidon GL, Levy RJ (1996) Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm Res 13: 1838-1845.
-
(1996)
Pharm Res
, vol.13
, pp. 1838-1845
-
-
Desai, M.P.1
Labhasetwar, V.2
Amidon, G.L.3
Levy, R.J.4
-
35
-
-
0034950338
-
Tetanus toxoid loaded nanoparticles from sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide): Evaluation of antibody response after oral and nasal application inmice
-
Jung T, Kamm W, Breitenbach A, Hungerer K-D, Hundt E, Kissel T (2001) Tetanus toxoid loaded nanoparticles from sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide): evaluation of antibody response after oral and nasal application inmice. Pharm Res 18: 352-360.
-
(2001)
Pharm Res
, vol.18
, pp. 352-360
-
-
Jung, T.1
Kamm, W.2
Breitenbach, A.3
Hungerer, K.-D.4
Hundt, E.5
Kissel, T.6
-
36
-
-
21744458087
-
Nanoparticle uptake by the oral route: Fulfilling its potential?
-
Florence AT (2005) Nanoparticle uptake by the oral route: fulfilling its potential? Drug Discov Today 2: 75-81.
-
(2005)
Drug Discov Today
, vol.2
, pp. 75-81
-
-
Florence, A.T.1
-
37
-
-
33947265152
-
An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells
-
des Rieux A, Fievez V, Theate I, Mast J, Preat V, Schneider YJ (2007) An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells. Eur J Pharm Sci 30: 380-391.
-
(2007)
Eur J Pharm Sci
, vol.30
, pp. 380-391
-
-
des Rieux, A.1
Fievez, V.2
Theate, I.3
Mast, J.4
Preat, V.5
Schneider, Y.J.6
-
38
-
-
33751253462
-
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
-
des Rieux A, Fievez V, Garinot M, Schneider Y-J, Préat V (2006) Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J Control Release 116: 1-27.
-
(2006)
J Control Release
, vol.116
, pp. 1-27
-
-
des Rieux, A.1
Fievez, V.2
Garinot, M.3
Schneider, Y.-J.4
Préat, V.5
-
39
-
-
0024953407
-
The uptake and translocation of latex nanospheres and microspheres after oral administration to rats
-
Jani P, Halbert GW, Langridge J, Florence AT (1989) The uptake and translocation of latex nanospheres and microspheres after oral administration to rats. J Pharm Pharmacol 41: 809-812.
-
(1989)
J Pharm Pharmacol
, vol.41
, pp. 809-812
-
-
Jani, P.1
Halbert, G.W.2
Langridge, J.3
Florence, A.T.4
-
40
-
-
23244464797
-
Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by peyer's patches in mice
-
Shakweh M, Besnard M, Nicolas V, Fattal E (2005) Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by peyer's patches in mice. Eur J Pharm Biopharm 61: 1-13.
-
(2005)
Eur J Pharm Biopharm
, vol.61
, pp. 1-13
-
-
Shakweh, M.1
Besnard, M.2
Nicolas, V.3
Fattal, E.4
-
41
-
-
57049085726
-
Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier
-
Wang YY, Lai SK, Suk JS, Pace A, Cone R, Hanes J (2008) Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier. Angew Chem Int Ed Engl 47: 9726-9729.
-
(2008)
Angew Chem Int Ed Engl
, vol.47
, pp. 9726-9729
-
-
Wang, Y.Y.1
Lai, S.K.2
Suk, J.S.3
Pace, A.4
Cone, R.5
Hanes, J.6
-
42
-
-
73349140554
-
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
-
Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J (2009) Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci U S A 106: 19268-19273.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19268-19273
-
-
Tang, B.C.1
Dawson, M.2
Lai, S.K.3
Wang, Y.Y.4
Suk, J.S.5
Yang, M.6
Zeitlin, P.7
Boyle, M.P.8
Fu, J.9
Hanes, J.10
-
43
-
-
26644454810
-
The basics and underlying mechanisms of mucoadhesion
-
Smart JD (2005) The basics and underlying mechanisms of mucoadhesion. Adv Drug Deliv Rev 57: 1556-1568.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 1556-1568
-
-
Smart, J.D.1
-
44
-
-
0037523228
-
Visualization of insulin-loaded nanocapsules: In vitro and in vivo studies after oral administration to rats
-
Pinto-Alphandary H, Aboubakar M, Jaillard D, Couvreur P, Vauthier C (2003) Visualization of insulin-loaded nanocapsules: in vitro and in vivo studies after oral administration to rats. Pharm Res 20: 1071-1084.
-
(2003)
Pharm Res
, vol.20
, pp. 1071-1084
-
-
Pinto-Alphandary, H.1
Aboubakar, M.2
Jaillard, D.3
Couvreur, P.4
Vauthier, C.5
-
45
-
-
79953242692
-
Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa
-
Dünnhaupt S, Barthelmes J, Hombach J, Sakloetsakun D, Arkhipova V, Bernkop-Schnürch A (2011) Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa. Int J Pharm 408: 191-199.
-
(2011)
Int J Pharm
, vol.408
, pp. 191-199
-
-
Dünnhaupt, S.1
Barthelmes, J.2
Hombach, J.3
Sakloetsakun, D.4
Arkhipova, V.5
Bernkop-Schnürch, A.6
-
46
-
-
79958174556
-
Advances in mucoadhesion and mucoadhesive polymers
-
Khutoryanskiy VV (2011) Advances in mucoadhesion and mucoadhesive polymers. Macromol Biosci 11: 748-764.
-
(2011)
Macromol Biosci
, vol.11
, pp. 748-764
-
-
Khutoryanskiy, V.V.1
-
47
-
-
0028092036
-
Improving insulin therapy-achievements and challenges
-
Galloway JA, Chance RE (1994) Improving insulin therapy-achievements and challenges. Horm Metab Res 26: 591-598.
-
(1994)
Horm Metab Res
, vol.26
, pp. 591-598
-
-
Galloway, J.A.1
Chance, R.E.2
-
48
-
-
0035888373
-
Insulin therapies-past, present and future
-
Pillai O, Panchagnula R (2001) Insulin therapies-past, present and future. Drug Discov Today 6: 1056-1061.
-
(2001)
Drug Discov Today
, vol.6
, pp. 1056-1061
-
-
Pillai, O.1
Panchagnula, R.2
-
49
-
-
79960647274
-
Novel applications for glycosylphosphatidylinositol-anchored proteins in pharmaceutical and industrial biotechnology
-
Müller G (2011) Novel applications for glycosylphosphatidylinositol-anchored proteins in pharmaceutical and industrial biotechnology. Mol Membr Biol 28: 187-205.
-
(2011)
Mol Membr Biol
, vol.28
, pp. 187-205
-
-
Müller, G.1
-
50
-
-
77952491719
-
Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery
-
Roger E, Lagarce F, Garcion E, Benoit JP (2010) Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery. Nanomedicine (Lond) 5: 287-306.
-
(2010)
Nanomedicine (Lond)
, vol.5
, pp. 287-306
-
-
Roger, E.1
Lagarce, F.2
Garcion, E.3
Benoit, J.P.4
-
51
-
-
14544286414
-
Particle uptake by Peyer's patches: A pathway for drug and vaccine delivery
-
Shakweh M, Ponchel G, Fattal E (2004) Particle uptake by Peyer's patches: a pathway for drug and vaccine delivery. Expert Opin Drug Deliv 1: 141-163.
-
(2004)
Expert Opin Drug Deliv
, vol.1
, pp. 141-163
-
-
Shakweh, M.1
Ponchel, G.2
Fattal, E.3
-
52
-
-
0030952669
-
Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat
-
Hussain N, Jani PU, Florence AT (1997) Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat. Pharm Res 14: 613-618.
-
(1997)
Pharm Res
, vol.14
, pp. 613-618
-
-
Hussain, N.1
Jani, P.U.2
Florence, A.T.3
-
53
-
-
3042664192
-
Use of targeting agents to increase uptake and localization of drugs to the intestinal epithelium
-
Russell-Jones GJ (2004) Use of targeting agents to increase uptake and localization of drugs to the intestinal epithelium. J Drug Target 12: 113-123.
-
(2004)
J Drug Target
, vol.12
, pp. 113-123
-
-
Russell-Jones, G.J.1
-
54
-
-
6344256207
-
Binding and uptake of wheat germ agglutinin-grafted PLGA-nanospheres by Caco-2 monolayers
-
Weissenboeck A, Bogner E, Wirth M, Gabor F (2004) Binding and uptake of wheat germ agglutinin-grafted PLGA-nanospheres by Caco-2 monolayers. Pharm Res 21: 1917-1923.
-
(2004)
Pharm Res
, vol.21
, pp. 1917-1923
-
-
Weissenboeck, A.1
Bogner, E.2
Wirth, M.3
Gabor, F.4
-
55
-
-
0242351939
-
Silver nanoparticle enhanced immunoassays: One step real time kinetic assay for insulin in serum
-
Lochner N, Lobmaier C, Wirth M, Leitner A, Pittner F, Gabor F (2003) Silver nanoparticle enhanced immunoassays: one step real time kinetic assay for insulin in serum. Eur J Pharm Biopharm 56: 469-477.
-
(2003)
Eur J Pharm Biopharm
, vol.56
, pp. 469-477
-
-
Lochner, N.1
Lobmaier, C.2
Wirth, M.3
Leitner, A.4
Pittner, F.5
Gabor, F.6
-
56
-
-
48849088009
-
Vitamin B12 as a carrier for the oral delivery of insulin
-
Petrus A, Vortherms A, Fairchild T, Doyle R (2007) Vitamin B12 as a carrier for the oral delivery of insulin. ChemMedChem 2: 1717-1721.
-
(2007)
ChemMedChem
, vol.2
, pp. 1717-1721
-
-
Petrus, A.1
Vortherms, A.2
Fairchild, T.3
Doyle, R.4
-
57
-
-
34447577190
-
Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles
-
Chalasani K, Russell-Jones G, Jain A, Diwan P, Jain S (2007) Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles. J Control Release 122: 141-150.
-
(2007)
J Control Release
, vol.122
, pp. 141-150
-
-
Chalasani, K.1
Russell-Jones, G.2
Jain, A.3
Diwan, P.4
Jain, S.5
-
58
-
-
0033229905
-
Synthesis and biological activity of ribose-50-carbamate derivatives of vitamin B12
-
McEwan JF, Veitch HS, Russell-Jones GJ (1999) Synthesis and biological activity of ribose-50-carbamate derivatives of vitamin B12. Bioconjug Chem 10: 1131-1136.
-
(1999)
Bioconjug Chem
, vol.10
, pp. 1131-1136
-
-
McEwan, J.F.1
Veitch, H.S.2
Russell-Jones, G.J.3
-
59
-
-
33846940490
-
A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin
-
Chalasani KB, Russell-Jones GJ, Yandrapu SK, Diwan PV, Jain SK (2007) A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin. J Control Release 117: 421-429.
-
(2007)
J Control Release
, vol.117
, pp. 421-429
-
-
Chalasani, K.B.1
Russell-Jones, G.J.2
Yandrapu, S.K.3
Diwan, P.V.4
Jain, S.K.5
-
60
-
-
0242584996
-
Wheat germ agglutinin binds to the epidermal growth factor receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence
-
Lochner N, Pittner F, Wirth M, Gabor F (2003) Wheat germ agglutinin binds to the epidermal growth factor receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence. Pharm Res 20: 833-839.
-
(2003)
Pharm Res
, vol.20
, pp. 833-839
-
-
Lochner, N.1
Pittner, F.2
Wirth, M.3
Gabor, F.4
-
61
-
-
34248227584
-
Thematic review series: Lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: How we learned to stop worrying and love glycophospholipids
-
Orlean P, Menon AK (2007) Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids. J Lipid Res 48: 993-1011.
-
(2007)
J Lipid Res
, vol.48
, pp. 993-1011
-
-
Orlean, P.1
Menon, A.K.2
-
62
-
-
0023520885
-
Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters
-
Pappenheimer JR (1987) Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters. J Membr Biol 100: 137-148.
-
(1987)
J Membr Biol
, vol.100
, pp. 137-148
-
-
Pappenheimer, J.R.1
-
63
-
-
0025954040
-
Mechanisms of peptide and protein absorption. 1. Paracellular intestinal transport-modulation of absorption
-
Nellans HN (1991) Mechanisms of peptide and protein absorption. 1. Paracellular intestinal transport-modulation of absorption. Adv Drug Deliv Rev 7: 339-364.
-
(1991)
Adv Drug Deliv Rev
, vol.7
, pp. 339-364
-
-
Nellans, H.N.1
-
64
-
-
16244418685
-
Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium
-
Salamat-Miller N, Johnston TP (2005) Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium. Int J Pharm 294: 201-216.
-
(2005)
Int J Pharm
, vol.294
, pp. 201-216
-
-
Salamat-Miller, N.1
Johnston, T.P.2
-
66
-
-
45749109076
-
Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation
-
Mi FL, Wu YY, Lin YH, Sonaje K, Ho YC, Chen CT, Juang JH, Sung HW (2008) Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation. Bioconjug Chem 19: 1248-1255.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 1248-1255
-
-
Mi, F.L.1
Wu, Y.Y.2
Lin, Y.H.3
Sonaje, K.4
Ho, Y.C.5
Chen, C.T.6
Juang, J.H.7
Sung, H.W.8
-
67
-
-
56649089693
-
Multi-ioncrosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs
-
Lin YH, Sonaje K, Lin KM, Juang JH, Mi FL, Yang HW, Sung HW (2008) Multi-ioncrosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs. J Control Release 132: 141-149.
-
(2008)
J Control Release
, vol.132
, pp. 141-149
-
-
Lin, Y.H.1
Sonaje, K.2
Lin, K.M.3
Juang, J.H.4
Mi, F.L.5
Yang, H.W.6
Sung, H.W.7
-
68
-
-
33744552970
-
Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds
-
Cheng WP, Gray AI, Tetley L, Hang Tle B, Schatzlein AG, Uchegbu IF (2006) Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds. Biomacromolecules 7: 1509-1520.
-
(2006)
Biomacromolecules
, vol.7
, pp. 1509-1520
-
-
Cheng, W.P.1
Gray, A.I.2
Tetley, L.3
Hang Tle, B.4
Schatzlein, A.G.5
Uchegbu, I.F.6
-
69
-
-
0142042448
-
Engineering of dendrimer surfaces to enhance transepithelial transport and reduce cytotoxicity
-
Jevprasesphant R, Penny J, Attwood D, McKeown NB, D'Emanuele A (2003) Engineering of dendrimer surfaces to enhance transepithelial transport and reduce cytotoxicity. Pharm Res 20: 1543-1550.
-
(2003)
Pharm Res
, vol.20
, pp. 1543-1550
-
-
Jevprasesphant, R.1
Penny, J.2
Attwood, D.3
McKeown, N.B.4
D'Emanuele, A.5
-
70
-
-
42649142580
-
Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: Ex vivo and in vivo studies
-
Bayat A, Dorkoosh FA, Dehpour AR, Moezi L, Larijani B, Junginger HE, Rafiee-Tehrani M (2008) Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: ex vivo and in vivo studies. Int J Pharm 356: 259-266.
-
(2008)
Int J Pharm
, vol.356
, pp. 259-266
-
-
Bayat, A.1
Dorkoosh, F.A.2
Dehpour, A.R.3
Moezi, L.4
Larijani, B.5
Junginger, H.E.6
Rafiee-Tehrani, M.7
-
71
-
-
50249129610
-
Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
-
Sadeghi AM, Dorkoosh FA, Avadi MR, Weinhold M, Bayat A, Delie F, Gurny R, Larijani B, Rafiee-Tehrani M, Junginger HE (2008) Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells. Eur J Pharm Biopharm 70: 270-278.
-
(2008)
Eur J Pharm Biopharm
, vol.70
, pp. 270-278
-
-
Sadeghi, A.M.1
Dorkoosh, F.A.2
Avadi, M.R.3
Weinhold, M.4
Bayat, A.5
Delie, F.6
Gurny, R.7
Larijani, B.8
Rafiee-Tehrani, M.9
Junginger, H.E.10
-
72
-
-
0035813752
-
Oral drug absorption enhancement by chitosan and its derivatives
-
Thanou M, Verhoef JC, Junginger HE (2001) Oral drug absorption enhancement by chitosan and its derivatives. Adv Drug Deliv Rev 52: 117-126.
-
(2001)
Adv Drug Deliv Rev
, vol.52
, pp. 117-126
-
-
Thanou, M.1
Verhoef, J.C.2
Junginger, H.E.3
-
73
-
-
0028071051
-
Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)
-
Artursson P, Lindmark T, Davis SS, Illum L (1994) Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm Res 11: 1358-1361.
-
(1994)
Pharm Res
, vol.11
, pp. 1358-1361
-
-
Artursson, P.1
Lindmark, T.2
Davis, S.S.3
Illum, L.4
-
74
-
-
0031574261
-
Chitosans for enhanced delivery of therapeutic peptides across intestinal epithelia: In vitro evaluation in Caco-2 cell monolayers
-
Kotzé AF, de Leeuw BJ, Lueßen HL, de Boer AG, Verhoef JC, Junginger HE (1997) Chitosans for enhanced delivery of therapeutic peptides across intestinal epithelia: in vitro evaluation in Caco-2 cell monolayers. Int J Pharm 159: 243-253.
-
(1997)
Int J Pharm
, vol.159
, pp. 243-253
-
-
Kotzé, A.F.1
de Leeuw, B.J.2
Lueßen, H.L.3
de Boer, A.G.4
Verhoef, J.C.5
Junginger, H.E.6
-
76
-
-
0036123018
-
The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line
-
Ranaldi G, Marigliano I, Vespignani I, Perozzi G, Sambuy Y (2002) The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line. J Nutr Biochem 13: 157-167.
-
(2002)
J Nutr Biochem
, vol.13
, pp. 157-167
-
-
Ranaldi, G.1
Marigliano, I.2
Vespignani, I.3
Perozzi, G.4
Sambuy, Y.5
-
77
-
-
0033960143
-
Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers
-
Thanou MM, Kotzé AF, Scharringhausen T, Luessen HL, de Boer AG, Verhoef JC, Junginger HE (2000) Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers. J Control Release 64: 15-25.
-
(2000)
J Control Release
, vol.64
, pp. 15-25
-
-
Thanou, M.M.1
Kotzé, A.F.2
Scharringhausen, T.3
Luessen, H.L.4
de Boer, A.G.5
Verhoef, J.C.6
Junginger, H.E.7
-
78
-
-
79955619433
-
Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by Caco-2 cells-towards oral insulin
-
Thompson C, Cheng W, Gadad P, Skene K, Smith M, Smith G, McKinnon A, Knott R (2011) Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by Caco-2 cells-towards oral insulin. Pharm Res 28: 886-896.
-
(2011)
Pharm Res
, vol.28
, pp. 886-896
-
-
Thompson, C.1
Cheng, W.2
Gadad, P.3
Skene, K.4
Smith, M.5
Smith, G.6
McKinnon, A.7
Knott, R.8
-
79
-
-
67349139863
-
The complexation between novel comb shaped amphiphilic polyallylamine and insulin-towards oral insulin delivery
-
Thompson CJ, Tetley L, Uchegbu IF, Cheng WP (2009) The complexation between novel comb shaped amphiphilic polyallylamine and insulin-towards oral insulin delivery. Int J Pharm 376: 46-55.
-
(2009)
Int J Pharm
, vol.376
, pp. 46-55
-
-
Thompson, C.J.1
Tetley, L.2
Uchegbu, I.F.3
Cheng, W.P.4
-
80
-
-
79957529691
-
Facilitated nanoscale delivery of insulin across intestinal membrane models
-
Woitiski CB, Sarmento B, Carvalho RA, Neufeld RJ, Veiga F (2011) Facilitated nanoscale delivery of insulin across intestinal membrane models. Int J Pharm 412: 123-131.
-
(2011)
Int J Pharm
, vol.412
, pp. 123-131
-
-
Woitiski, C.B.1
Sarmento, B.2
Carvalho, R.A.3
Neufeld, R.J.4
Veiga, F.5
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