Dysregulation of system xc- expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice

Neurochemistry International

Volumn 76, Issue , 2014, Pages 59-69

  Frederick, Natalie M ^a   Bertho, Julie ^a,b   Patel, Kishan K ^a   Petr, Geraldine T ^a,c   Bakradze, Ekaterina ^a,d   Smith, Sylvia B ^e   Rosenberg, Paul A ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Georgia   (Georgia)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Glutamate uptake; Glutathione; Huntington's disease; Oxidative stress; STHdh cells; xCT

Indexed keywords

CD98 ANTIGEN; GLUTATHIONE; HUNTINGTIN; MESSENGER RNA; MUTANT PROTEIN; REACTIVE OXYGEN METABOLITE; AMINO ACID TRANSPORTER; HUNTINGTON PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN; PRIMER DNA; SLC7A11 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAG REPEAT; CELL ISOLATION; CONTROLLED STUDY; FEMALE; HUNTINGTON CHOREA; IN VIVO STUDY; MALE; MOUSE; NEURAL STEM CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; ANIMAL; CELL LINE; CORPUS STRIATUM; CYTOLOGY; GENETICS; METABOLISM; MUTATION; NERVE CELL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; TRINUCLEOTIDE REPEAT;

AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; BASE SEQUENCE; CELL LINE; CORPUS STRIATUM; DNA PRIMERS; MICE; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRINUCLEOTIDE REPEATS;

EID: 84905165974     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2014.06.017     Document Type: Article

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