-
1
-
-
23944431858
-
Nutritional control of gene expression: How mammalian cells respond to amino acid limitation
-
Kilberg M.S., et al. Nutritional control of gene expression: How mammalian cells respond to amino acid limitation. Annu. Rev. Nutr. 25 (2005) 59-85
-
(2005)
Annu. Rev. Nutr.
, vol.25
, pp. 59-85
-
-
Kilberg, M.S.1
-
2
-
-
41449095062
-
Phosphorylation of eIF2 directs ATF5 Translational control in response to diverse stress conditions
-
Zhou D., et al. Phosphorylation of eIF2 directs ATF5 Translational control in response to diverse stress conditions. J. Biol. Chem. 283 (2008) 7064-7073
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7064-7073
-
-
Zhou, D.1
-
3
-
-
65449141379
-
An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation
-
Lee Y.Y., et al. An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation. J. Biol. Chem. 284 (2009) 6661-6673
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 6661-6673
-
-
Lee, Y.Y.1
-
4
-
-
3843117589
-
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
-
Vattem K.M., and Wek R.C. Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc. Natl. Acad. Sci. U. S. A 101 (2004) 11269-11274
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 11269-11274
-
-
Vattem, K.M.1
Wek, R.C.2
-
5
-
-
5444264022
-
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
-
Lu P.D., et al. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J. Cell Biol. 167 (2004) 27-33
-
(2004)
J. Cell Biol.
, vol.167
, pp. 27-33
-
-
Lu, P.D.1
-
6
-
-
57249111805
-
The transcription factor ATF5: role in neurodevelopment and neural tumors
-
Green L.A., et al. The transcription factor ATF5: role in neurodevelopment and neural tumors. J. Neurochem. 108 (2009) 11-22
-
(2009)
J. Neurochem.
, vol.108
, pp. 11-22
-
-
Green, L.A.1
-
7
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α
-
Novoa I., et al. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α. J. Cell Biol 153 (2001) 1011-1021
-
(2001)
J. Cell Biol
, vol.153
, pp. 1011-1021
-
-
Novoa, I.1
-
8
-
-
0037317592
-
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2
-
Brush M.H., et al. Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol. Cell Biol. 23 (2003) 1292-1303
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 1292-1303
-
-
Brush, M.H.1
-
9
-
-
0037416211
-
Stress-induced gene expression requires programmed recovery from translational repression
-
Novoa I., et al. Stress-induced gene expression requires programmed recovery from translational repression. EMBO J. 22 (2003) 1180-1187
-
(2003)
EMBO J.
, vol.22
, pp. 1180-1187
-
-
Novoa, I.1
-
10
-
-
0030867942
-
gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3
-
Wolfgang C.D., et al. gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3. Mol. Cell Biol. 17 (1997) 6700-6707
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 6700-6707
-
-
Wolfgang, C.D.1
-
11
-
-
0033118409
-
Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
-
Fawcett T.W., et al. Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem. J. 339 (1999) 135-141
-
(1999)
Biochem. J.
, vol.339
, pp. 135-141
-
-
Fawcett, T.W.1
-
12
-
-
55549114713
-
Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells
-
Gjymishka A., et al. Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells. J. Biol. Chem. 283 (2008) 27736-27747
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27736-27747
-
-
Gjymishka, A.1
-
13
-
-
0036898131
-
Dietary protein quantity and quality affect rat hepatic gene expression
-
Endo Y., et al. Dietary protein quantity and quality affect rat hepatic gene expression. J. Nutr. 132 (2002) 3632-3637
-
(2002)
J. Nutr.
, vol.132
, pp. 3632-3637
-
-
Endo, Y.1
-
14
-
-
0036463655
-
Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress
-
Hinnebusch A.G., and Natarajan K. Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress. Eukaryot. Cell 1 (2002) 22-32
-
(2002)
Eukaryot. Cell
, vol.1
, pp. 22-32
-
-
Hinnebusch, A.G.1
Natarajan, K.2
-
15
-
-
0035924082
-
Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview
-
Roseboom T.J., et al. Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview. Mol. Cell Endocrinol. 185 (2001) 93-98
-
(2001)
Mol. Cell Endocrinol.
, vol.185
, pp. 93-98
-
-
Roseboom, T.J.1
-
16
-
-
35548941189
-
Epigenetic epidemiology of the developmental origins hypothesis
-
Waterland R.A., and Michels K.B. Epigenetic epidemiology of the developmental origins hypothesis. Annu. Rev. Nutr. 27 (2007) 363-388
-
(2007)
Annu. Rev. Nutr.
, vol.27
, pp. 363-388
-
-
Waterland, R.A.1
Michels, K.B.2
-
17
-
-
0032923528
-
Potential mechanisms of metabolic imprinting that lead to chronic disease
-
Waterland R.A., and Garza C. Potential mechanisms of metabolic imprinting that lead to chronic disease. Am. J. Clin. Nutr. 69 (1999) 179-197
-
(1999)
Am. J. Clin. Nutr.
, vol.69
, pp. 179-197
-
-
Waterland, R.A.1
Garza, C.2
-
18
-
-
20444411948
-
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
-
Lillycrop K.A., et al. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J. Nutr. 135 (2005) 1382-1386
-
(2005)
J. Nutr.
, vol.135
, pp. 1382-1386
-
-
Lillycrop, K.A.1
-
19
-
-
32044443648
-
Nutritional homeostasis and indispensable amino acid sensing: a new solution to an old puzzle
-
Gietzen D.W., and Rogers Q.R. Nutritional homeostasis and indispensable amino acid sensing: a new solution to an old puzzle. Trends Neurosci. 29 (2006) 91-99
-
(2006)
Trends Neurosci.
, vol.29
, pp. 91-99
-
-
Gietzen, D.W.1
Rogers, Q.R.2
-
20
-
-
4444316887
-
Diets deficient in indispensable amino acids rapidly decrease the concentration of the limiting amino acid in the anterior piriform cortex of rats
-
Koehnle T.J., et al. Diets deficient in indispensable amino acids rapidly decrease the concentration of the limiting amino acid in the anterior piriform cortex of rats. J. Nutr. 134 (2004) 2365-2371
-
(2004)
J. Nutr.
, vol.134
, pp. 2365-2371
-
-
Koehnle, T.J.1
-
21
-
-
20144374658
-
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
-
Hao S., et al. Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex. Science 307 (2005) 1776-1778
-
(2005)
Science
, vol.307
, pp. 1776-1778
-
-
Hao, S.1
-
22
-
-
20144387009
-
The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores
-
Maurin A.C., et al. The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores. Cell Metab. 1 (2005) 273-277
-
(2005)
Cell Metab.
, vol.1
, pp. 273-277
-
-
Maurin, A.C.1
-
23
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding H.P., et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell 11 (2003) 619-633
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
-
24
-
-
43049143059
-
HepG2/C3A cells respond to cysteine-deprivation by induction of the amino acid deprivation/integrated stress response pathway
-
Lee J.I., et al. HepG2/C3A cells respond to cysteine-deprivation by induction of the amino acid deprivation/integrated stress response pathway. Physiol. Genomics 33 (2008) 218-229
-
(2008)
Physiol. Genomics
, vol.33
, pp. 218-229
-
-
Lee, J.I.1
-
25
-
-
8744224520
-
ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells
-
Yang X., and Karsenty G. ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells. J. Biol. Chem. 279 (2004) 47109-47114
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47109-47114
-
-
Yang, X.1
Karsenty, G.2
-
26
-
-
4344650113
-
Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2
-
Anthony T.G., et al. Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2. J. Biol. Chem. 279 (2004) 36553-36561
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36553-36561
-
-
Anthony, T.G.1
-
27
-
-
33846602706
-
The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid
-
Guo F., and Cavener D.R. The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid. Cell Metab. 5 (2007) 103-114
-
(2007)
Cell Metab.
, vol.5
, pp. 103-114
-
-
Guo, F.1
Cavener, D.R.2
-
28
-
-
27144510561
-
Translational regulation of GCN4 and the general amino acid control of yeast
-
Hinnebusch A.G. Translational regulation of GCN4 and the general amino acid control of yeast. Annu. Rev. Microbiol. 59 (2005) 407-450
-
(2005)
Annu. Rev. Microbiol.
, vol.59
, pp. 407-450
-
-
Hinnebusch, A.G.1
-
29
-
-
12344262761
-
Role of amino acids in the translational control of protein synthesis in mammals
-
Kimball S.R., and Jefferson L.S. Role of amino acids in the translational control of protein synthesis in mammals. Semin. Cell Dev. Biol. 16 (2005) 21-27
-
(2005)
Semin. Cell Dev. Biol.
, vol.16
, pp. 21-27
-
-
Kimball, S.R.1
Jefferson, L.S.2
-
31
-
-
41149141885
-
Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription
-
Thiaville M.M., et al. Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription. Biochem. J. 410 (2008) 473-484
-
(2008)
Biochem. J.
, vol.410
, pp. 473-484
-
-
Thiaville, M.M.1
-
32
-
-
1642458354
-
Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response
-
Jiang H.Y., et al. Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response. Mol. Cell. Biol. 24 (2004) 1365-1377
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1365-1377
-
-
Jiang, H.Y.1
-
33
-
-
33846277296
-
Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation
-
Pan Y.X., et al. Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation. Biochem. J. 401 (2007) 299-307
-
(2007)
Biochem. J.
, vol.401
, pp. 299-307
-
-
Pan, Y.X.1
-
34
-
-
34948868346
-
The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP
-
Cherasse Y., et al. The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP. Nucleic Acids Res. 35 (2007) 5954-5965
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 5954-5965
-
-
Cherasse, Y.1
-
35
-
-
0037025396
-
ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene
-
Siu F., et al. ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem. 277 (2002) 24120-24127
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24120-24127
-
-
Siu, F.1
-
36
-
-
33847005465
-
A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation
-
Lopez A.B., et al. A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation. Biochem. J. 402 (2007) 163-173
-
(2007)
Biochem. J.
, vol.402
, pp. 163-173
-
-
Lopez, A.B.1
-
37
-
-
0030054707
-
Effect of dietary protein restriction on liver transcription factors
-
Marten N.W., et al. Effect of dietary protein restriction on liver transcription factors. Biochem. J. 317 (1996) 361-370
-
(1996)
Biochem. J.
, vol.317
, pp. 361-370
-
-
Marten, N.W.1
-
38
-
-
10944269132
-
Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive bZIP transcription factors as well as localized histone acetylation
-
Chen H., et al. Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive bZIP transcription factors as well as localized histone acetylation. J. Biol. Chem. 279 (2004) 50829-50839
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50829-50839
-
-
Chen, H.1
-
39
-
-
0032790516
-
ATF3 and stress responses
-
Hai T., et al. ATF3 and stress responses. Gene Expr. 7 (1999) 321-335
-
(1999)
Gene Expr.
, vol.7
, pp. 321-335
-
-
Hai, T.1
-
40
-
-
0141866865
-
Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple ATF3 mRNA species which, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter
-
Pan Y.-X., et al. Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple ATF3 mRNA species which, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter. J. Biol. Chem. 278 (2003) 38402-38412
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38402-38412
-
-
Pan, Y.-X.1
-
41
-
-
27144493076
-
Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization
-
Pan Y.X., et al. Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization. J. Biol. Chem. 280 (2005) 34609-34616
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 34609-34616
-
-
Pan, Y.X.1
-
42
-
-
58049203872
-
C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
-
Su N., and Kilberg M.S. C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene. J. Biol. Chem. 283 (2008) 35106-35117
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35106-35117
-
-
Su, N.1
Kilberg, M.S.2
-
43
-
-
58449089596
-
Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways
-
Deval C., et al. Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways. FEBS J. 276 (2009) 707-718
-
(2009)
FEBS J.
, vol.276
, pp. 707-718
-
-
Deval, C.1
-
44
-
-
0034282704
-
Activation of the human asparagine synthetase gene by the amino acid response and the endoplasmic reticulum stress response pathways occurs by common genomic elements
-
Barbosa-Tessmann I.P., et al. Activation of the human asparagine synthetase gene by the amino acid response and the endoplasmic reticulum stress response pathways occurs by common genomic elements. J. Biol. Chem. 275 (2000) 26976-26985
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26976-26985
-
-
Barbosa-Tessmann, I.P.1
-
45
-
-
0038338321
-
Characterization of the nutrient sensing response unit in the human asparagine synthetase promoter
-
Zhong C., et al. Characterization of the nutrient sensing response unit in the human asparagine synthetase promoter. Biochem. J. 372 (2003) 603-609
-
(2003)
Biochem. J.
, vol.372
, pp. 603-609
-
-
Zhong, C.1
-
46
-
-
33749474913
-
Alignment of the transcription start site coincides with increased transcriptional activity from the human asparagine synthetase gene following amino acid deprivation of HepG2 cells
-
Chen H., and Kilberg M.S. Alignment of the transcription start site coincides with increased transcriptional activity from the human asparagine synthetase gene following amino acid deprivation of HepG2 cells. J. Nutr. 136 (2006) 2463-2467
-
(2006)
J. Nutr.
, vol.136
, pp. 2463-2467
-
-
Chen, H.1
Kilberg, M.S.2
-
47
-
-
3142665989
-
Regulation of cationic amino acid transport: The story of the CAT-1 transporter
-
Hatzoglou M., et al. Regulation of cationic amino acid transport: The story of the CAT-1 transporter. Annu. Rev. Nutr. 24 (2004) 377-399
-
(2004)
Annu. Rev. Nutr.
, vol.24
, pp. 377-399
-
-
Hatzoglou, M.1
-
48
-
-
1342281232
-
CATs and HATs: the SLC7 family of amino acid transporters
-
Verrey F., et al. CATs and HATs: the SLC7 family of amino acid transporters. Pflugers Arch. 447 (2004) 532-542
-
(2004)
Pflugers Arch.
, vol.447
, pp. 532-542
-
-
Verrey, F.1
-
49
-
-
0038064178
-
The zipper model of translational control. A small upstream ORF is the switch that controls structural remodeling of an mRNA leader
-
Yaman I., et al. The zipper model of translational control. A small upstream ORF is the switch that controls structural remodeling of an mRNA leader. Cell 113 (2003) 519-531
-
(2003)
Cell
, vol.113
, pp. 519-531
-
-
Yaman, I.1
-
50
-
-
0036829750
-
Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR
-
Yaman I., et al. Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR. J. Biol. Chem. 277 (2002) 41539-41546
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41539-41546
-
-
Yaman, I.1
-
51
-
-
33744973775
-
Relief of microRNA-mediated translational repression in human cells subjected to stress
-
Bhattacharyya S.N., et al. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125 (2006) 1111-1124
-
(2006)
Cell
, vol.125
, pp. 1111-1124
-
-
Bhattacharyya, S.N.1
-
52
-
-
0030814110
-
Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels
-
Bruhat A., et al. Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. J. Biol. Chem. 272 (1997) 17588-17593
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17588-17593
-
-
Bruhat, A.1
-
53
-
-
0033214640
-
Glutamine deprivation induces the expression of GADD45 and GADD153 primarily by mRNA stabilization
-
Abcouwer S.F., et al. Glutamine deprivation induces the expression of GADD45 and GADD153 primarily by mRNA stabilization. J. Biol. Chem. 274 (1999) 28645-28651
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28645-28651
-
-
Abcouwer, S.F.1
-
54
-
-
1242272070
-
Induction of CHOP expression by amino acid limitation requires Both ATF4 expression and ATF2 phosphorylation
-
Averous J., et al. Induction of CHOP expression by amino acid limitation requires Both ATF4 expression and ATF2 phosphorylation. J. Biol. Chem. 279 (2004) 5288-5297
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5288-5297
-
-
Averous, J.1
-
55
-
-
17144417669
-
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
-
Ohoka N., et al. TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J. 24 (2005) 1243-1255
-
(2005)
EMBO J.
, vol.24
, pp. 1243-1255
-
-
Ohoka, N.1
-
56
-
-
0026546365
-
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
-
Ron D., and Habener J.F. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Gene. Devel. 6 (1992) 439-453
-
(1992)
Gene. Devel.
, vol.6
, pp. 439-453
-
-
Ron, D.1
Habener, J.F.2
-
57
-
-
0032127493
-
Identification of novel stress-induced genes downstream of chop
-
Wang X.-Z., et al. Identification of novel stress-induced genes downstream of chop. EMBO J. 17 (1998) 3619-3630
-
(1998)
EMBO J.
, vol.17
, pp. 3619-3630
-
-
Wang, X.-Z.1
-
58
-
-
0038682500
-
Amino acid transporters: roles in amino acid sensing and signalling in animal cells
-
Hyde R., et al. Amino acid transporters: roles in amino acid sensing and signalling in animal cells. Biochem. J. 373 (2003) 1-18
-
(2003)
Biochem. J.
, vol.373
, pp. 1-18
-
-
Hyde, R.1
-
59
-
-
1242317638
-
Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family
-
Mackenzie B., and Erickson J.D. Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. Pflugers Arch. 447 (2004) 784-795
-
(2004)
Pflugers Arch.
, vol.447
, pp. 784-795
-
-
Mackenzie, B.1
Erickson, J.D.2
-
60
-
-
0035795723
-
Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A
-
Ling R., et al. Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A. Biochim. Biophys. Acta 1512 (2001) 15-21
-
(2001)
Biochim. Biophys. Acta
, vol.1512
, pp. 15-21
-
-
Ling, R.1
-
61
-
-
0035830702
-
The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression
-
Gazzola R.F., et al. The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression. FEBS Lett. 490 (2001) 11-14
-
(2001)
FEBS Lett.
, vol.490
, pp. 11-14
-
-
Gazzola, R.F.1
-
62
-
-
0036790040
-
The mechanism for transcriptional activation of the human ATA2 transporter gene by amino acid deprivation is different than that for asparagine synthetase
-
Bain P.J., et al. The mechanism for transcriptional activation of the human ATA2 transporter gene by amino acid deprivation is different than that for asparagine synthetase. J. Nutr. 132 (2002) 3023-3029
-
(2002)
J. Nutr.
, vol.132
, pp. 3023-3029
-
-
Bain, P.J.1
-
63
-
-
0942265548
-
Transcriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is mediated by an intronic element
-
Palii S.S., et al. Transcriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is mediated by an intronic element. J. Biol. Chem. 279 (2004) 3463-3471
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3463-3471
-
-
Palii, S.S.1
-
64
-
-
33646228377
-
Characterization of the amino acid response element within the human SNAT2 system A transporter gene
-
Palii S.S., et al. Characterization of the amino acid response element within the human SNAT2 system A transporter gene. Biochem. J. 395 (2006) 517-527
-
(2006)
Biochem. J.
, vol.395
, pp. 517-527
-
-
Palii, S.S.1
-
65
-
-
0033213632
-
Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator
-
Natarajan K., et al. Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator. Mol. Cell 4 (1999) 657-664
-
(1999)
Mol. Cell
, vol.4
, pp. 657-664
-
-
Natarajan, K.1
-
66
-
-
33644852483
-
Mediator as a general transcription factor
-
Takagi Y., and Kornberg R.D. Mediator as a general transcription factor. J. Biol. Chem. 281 (2006) 80-89
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 80-89
-
-
Takagi, Y.1
Kornberg, R.D.2
-
67
-
-
32244438509
-
Activator-specific recruitment of Mediator in vivo
-
Fan X., et al. Activator-specific recruitment of Mediator in vivo. Nat. Struct. Mol. Biol. 13 (2006) 117-120
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 117-120
-
-
Fan, X.1
-
68
-
-
55249112985
-
Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex
-
Thiaville M.M., et al. Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex. Nucleic Acids Res. 36 (2008) 5571-5580
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 5571-5580
-
-
Thiaville, M.M.1
-
69
-
-
34548647535
-
TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4
-
Ord D., et al. TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4. Exp. Cell Res. 313 (2007) 3556-3567
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 3556-3567
-
-
Ord, D.1
-
70
-
-
15444370110
-
Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions
-
Ord D., and Ord T. Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions. Biochem. Biophys. Res. Commun. 330 (2005) 210-218
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.330
, pp. 210-218
-
-
Ord, D.1
Ord, T.2
-
71
-
-
18544396997
-
Mouse NIPK interacts with ATF4 and affects its transcriptional activity
-
Ord D., and Ord T. Mouse NIPK interacts with ATF4 and affects its transcriptional activity. Exp. Cell Res. 286 (2003) 308-320
-
(2003)
Exp. Cell Res.
, vol.286
, pp. 308-320
-
-
Ord, D.1
Ord, T.2
-
72
-
-
0037954623
-
SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia
-
Bowers A.J., et al. SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia. Oncogene 22 (2003) 2823-2835
-
(2003)
Oncogene
, vol.22
, pp. 2823-2835
-
-
Bowers, A.J.1
-
73
-
-
44849104383
-
MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells
-
Thiaville M.M., et al. MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells. J. Biol. Chem. 283 (2008) 10848-10857
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10848-10857
-
-
Thiaville, M.M.1
-
74
-
-
57749206796
-
SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression
-
Jin H.O., et al. SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression. FEBS Lett. 583 (2009) 123-127
-
(2009)
FEBS Lett.
, vol.583
, pp. 123-127
-
-
Jin, H.O.1
-
75
-
-
33746215231
-
Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1
-
Monick M.M., et al. Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1. J. Immunol. 177 (2006) 1636-1645
-
(2006)
J. Immunol.
, vol.177
, pp. 1636-1645
-
-
Monick, M.M.1
-
76
-
-
0032832476
-
Adaptive increase of amino acid transport System A requires ERK1/2 activation
-
Franchi-Gazzola R., et al. Adaptive increase of amino acid transport System A requires ERK1/2 activation. J. Biol. Chem. 274 (1999) 28922-28928
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28922-28928
-
-
Franchi-Gazzola, R.1
-
77
-
-
1842833391
-
Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mrna stabilization
-
Leung-Pineda V., et al. Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mrna stabilization. Biochem. J. 379 (2004) 79-88
-
(2004)
Biochem. J.
, vol.379
, pp. 79-88
-
-
Leung-Pineda, V.1
-
78
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma X.M., and Blenis J. Molecular mechanisms of mTOR-mediated translational control. Nat. Rev. Mol. Cell Biol. 10 (2009) 307-318
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
79
-
-
58149524838
-
ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression
-
Whitney M.L., et al. ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression. Biochem. Biophys. Res. Commun. 379 (2009) 451-455
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.379
, pp. 451-455
-
-
Whitney, M.L.1
-
80
-
-
59749096227
-
Amino acid transporters: eminences grises of nutrient signalling mechanisms?
-
Taylor P.M. Amino acid transporters: eminences grises of nutrient signalling mechanisms?. Biochem. Soc. Trans. 37 (2009) 237-241
-
(2009)
Biochem. Soc. Trans.
, vol.37
, pp. 237-241
-
-
Taylor, P.M.1
|