Reagents that block neuronal death from Huntington's disease also curb oxidative stress

NeuroReport

Volumn 23, Issue 1, 2012, Pages 10-15

  Valencia, Antonio ^a   Sapp, Ellen ^a   Reeves, Patrick B ^a   Alexander, Jonathan ^a   Masso, Nicholas ^a   Li, Xueyi ^a   Kegel, Kimberly B ^a   DiFiglia, Marian ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

brain derived neurotropic factor; glycogen synthase kinase 3 b; mutant huntingtin; N acetyl cysteine; neurodegeneration; reactive oxygen species

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; ACETYLCYSTEINE; BRAIN DERIVED NEUROTROPHIC FACTOR; GLUTAMINE; HUNTINGTIN; NEUROPROTECTIVE AGENT; NEUROTROPHIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; BRAIN DAMAGE; CELL SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; EMBRYO; EXON; GENE INSERTION; GENE MUTATION; HUNTINGTON CHOREA; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; ANTIOXIDANTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; GLYCOGEN SYNTHASE KINASE 3; HUNTINGTON DISEASE; INDICATORS AND REAGENTS; MALE; MICE; MICE, TRANSGENIC; MUTATION; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 82555176567     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0b013e32834d92e6     Document Type: Article

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