Regulation of the system x - C cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures

GLIA

Volumn 59, Issue 10, 2011, Pages 1387-1401

  Seib, Todd Michael ^a   Patel, Sarjubhai Amratbhai ^a   Bridges, Richard James ^a  

^a UNIVERSITY OF MONTANA   (United States)

Author keywords

Amino acid transport; Buthionine sulfoximine; Central nervous system; Cysteine cystine metabolism; DbcAMP; Electrophilic response element; Excitotoxicity; Glioma; Glutamic acid pharmacology; Immunoblotting; Oxidation reduction; Oxidative stress; Rats

Indexed keywords

BUTHIONINE SULFOXIMINE; CARRIER PROTEIN; CYCLIC AMP; CYSTINE; ELECTROPHILE; GLUTAMIC ACID; GLUTATHIONE; HETERODIMER; HYDROGEN PEROXIDE; MESSENGER RNA; PROTEIN SUBUNIT; SX C TRANSPORTER; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; XCT PROTEIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL LEVEL; CENTRAL NERVOUS SYSTEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATIONAL STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN TRANSPORT; RAT; REGULATORY MECHANISM; UPREGULATION;

AMINO ACID TRANSPORT SYSTEMS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIMETABOLITES; ASTROCYTES; BUTHIONINE SULFOXIMINE; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC CMP; CYSTINE; GLUTAMIC ACID; GLUTATHIONE; NF-E2-RELATED FACTOR 2; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRITIUM;

EID: 79960741110     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21176     Document Type: Article

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