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Volumn 62, Issue 7, 2013, Pages 973-981

Glutamate transporter expression and function in a striatal neuronal model of Huntington's disease

Author keywords

EAAC1; Glutamate transporters; Huntington's disease; Na+ dependent glutamate uptake; STHdH cells

Indexed keywords

GLUTAMATE TRANSPORTER; GLUTAMIC ACID; POTASSIUM CHANNEL; PROTEIN EAAC1; PROTEIN GLT 1B; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84875958901     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.02.026     Document Type: Article
Times cited : (9)

References (54)
  • 2
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • K. Aoyama, S.W. Suh, A.M. Hamby, J. Liu, W.Y. Chan, Y. Chen, and R.A. Swanson Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse Nat. Neurosci. 9 2006 119 126
    • (2006) Nat. Neurosci. , vol.9 , pp. 119-126
    • Aoyama, K.1    Suh, S.W.2    Hamby, A.M.3    Liu, J.4    Chan, W.Y.5    Chen, Y.6    Swanson, R.A.7
  • 3
    • 0030932152 scopus 로고    scopus 로고
    • Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
    • J.L. Arriza, S. Eliasof, M.P. Kavanaugh, and S.G. Amara Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance Proc. Natl. Acad. Sci. USA 94 1997 4155 4160
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4155-4160
    • Arriza, J.L.1    Eliasof, S.2    Kavanaugh, M.P.3    Amara, S.G.4
  • 5
    • 0028238967 scopus 로고
    • Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells
    • B. Barbour, B.U. Keller, I. Llano, and A. Marty Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells Neuron 12 1994 1331 1343
    • (1994) Neuron , vol.12 , pp. 1331-1343
    • Barbour, B.1    Keller, B.U.2    Llano, I.3    Marty, A.4
  • 6
    • 1542348209 scopus 로고    scopus 로고
    • The energetics of Huntington's disease
    • S.E. Browne, and M.F. Beal The energetics of Huntington's disease Neurochem. Res. 29 2004 531 546
    • (2004) Neurochem. Res. , vol.29 , pp. 531-546
    • Browne, S.E.1    Beal, M.F.2
  • 7
    • 0034283877 scopus 로고    scopus 로고
    • Transcriptional dysregulation in Huntington's disease
    • J.H. Cha Transcriptional dysregulation in Huntington's disease Trends Neurosci. 23 2000 387 392
    • (2000) Trends Neurosci. , vol.23 , pp. 387-392
    • Cha, J.H.1
  • 8
    • 0037088930 scopus 로고    scopus 로고
    • Expression of a variant form of the glutamate transporter GLT-1 in neuronal cultures and in neurons and astrocytes in the rat brain
    • W. Chen, C. Aoki, V. Mahadomrongkul, C.E. Gruber, G.J. Wang, R. Blitzblau, N. Irwin, and P.A. Rosenberg Expression of a variant form of the glutamate transporter GLT-1 in neuronal cultures and in neurons and astrocytes in the rat brain J. Neurosci. 22 2002 2142 2152
    • (2002) J. Neurosci. , vol.22 , pp. 2142-2152
    • Chen, W.1    Aoki, C.2    Mahadomrongkul, V.3    Gruber, C.E.4    Wang, G.J.5    Blitzblau, R.6    Irwin, N.7    Rosenberg, P.A.8
  • 11
    • 0031918486 scopus 로고    scopus 로고
    • EAAC1, a high-affinity glutamate tranporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex
    • F. Conti, S. DeBiasi, A. Minelli, J.D. Rothstein, and M. Melone EAAC1, a high-affinity glutamate tranporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex Cereb. Cortex 8 1998 108 116
    • (1998) Cereb. Cortex , vol.8 , pp. 108-116
    • Conti, F.1    Debiasi, S.2    Minelli, A.3    Rothstein, J.D.4    Melone, M.5
  • 12
    • 0017167057 scopus 로고
    • Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea
    • J.T. Coyle, and R. Schwarcz Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea Nature 263 1976 244 246
    • (1976) Nature , vol.263 , pp. 244-246
    • Coyle, J.T.1    Schwarcz, R.2
  • 13
    • 33749042331 scopus 로고    scopus 로고
    • Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
    • L. Cui, H. Jeong, F. Borovecki, C.N. Parkhurst, N. Tanese, and D. Krainc Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration Cell 127 2006 59 69
    • (2006) Cell , vol.127 , pp. 59-69
    • Cui, L.1    Jeong, H.2    Borovecki, F.3    Parkhurst, C.N.4    Tanese, N.5    Krainc, D.6
  • 15
    • 0025363346 scopus 로고
    • Excitotoxic injury of the neostriatum: A model for Huntington's disease
    • M. DiFiglia Excitotoxic injury of the neostriatum: a model for Huntington's disease Trends Neurosci. 13 1990 286 289
    • (1990) Trends Neurosci. , vol.13 , pp. 286-289
    • Difiglia, M.1
  • 16
    • 0029921679 scopus 로고    scopus 로고
    • +-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1)
    • +-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1) Mol. Pharmacol. 49 1996 465 473
    • (1996) Mol. Pharmacol. , vol.49 , pp. 465-473
    • Dowd, L.A.1    Coyle, A.J.2    Rothstein, J.D.3    Pritchett, D.B.4    Robinson, M.B.5
  • 17
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain
    • R. Dringen Metabolism and functions of glutathione in brain Prog. Neurobiol. 62 2000 649 671
    • (2000) Prog. Neurobiol. , vol.62 , pp. 649-671
    • Dringen, R.1
  • 19
    • 0029076899 scopus 로고
    • An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
    • W.A. Fairman, R.J. Vandenberg, J.L. Arriza, M.P. Kavanaugh, and S.G. Amara An excitatory amino-acid transporter with properties of a ligand-gated chloride channel Nature 375 1995 599 603
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 20
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
    • M.M. Fan, and L.A. Raymond N-methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease Prog. Neurobiol. 81 2007 272 293
    • (2007) Prog. Neurobiol. , vol.81 , pp. 272-293
    • Fan, M.M.1    Raymond, L.A.2
  • 24
    • 0346749473 scopus 로고    scopus 로고
    • Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-d-aspartate receptor activation in Huntington's disease knock-in striatal cells
    • S. Gines, E. Ivanova, I.S. Seong, C.A. Saura, and M.E. MacDonald Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-d-aspartate receptor activation in Huntington's disease knock-in striatal cells J. Biol. Chem. 278 2003 50514 50522
    • (2003) J. Biol. Chem. , vol.278 , pp. 50514-50522
    • Gines, S.1    Ivanova, E.2    Seong, I.S.3    Saura, C.A.4    MacDonald, M.E.5
  • 25
    • 36248960617 scopus 로고    scopus 로고
    • Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1
    • M.I. Gonzalez, B.T. Susarla, K.M. Fournier, A.L. Sheldon, and M.B. Robinson Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1 J. Neurochem. 103 2007 1917 1931
    • (2007) J. Neurochem. , vol.103 , pp. 1917-1931
    • Gonzalez, M.I.1    Susarla, B.T.2    Fournier, K.M.3    Sheldon, A.L.4    Robinson, M.B.5
  • 27
    • 0033961498 scopus 로고    scopus 로고
    • Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus
    • Y. He, W.G. Janssen, J.D. Rothstein, and J.H. Morrison Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus J. Comp. Neurol. 418 2000 255 269
    • (2000) J. Comp. Neurol. , vol.418 , pp. 255-269
    • He, Y.1    Janssen, W.G.2    Rothstein, J.D.3    Morrison, J.H.4
  • 28
    • 77955844498 scopus 로고    scopus 로고
    • Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease
    • K. Huang, M.H. Kang, C. Askew, R. Kang, S.S. Sanders, J. Wan, N.G. Davis, and M.R. Hayden Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease Neurobiol. Dis. 40 2010 207 215
    • (2010) Neurobiol. Dis. , vol.40 , pp. 207-215
    • Huang, K.1    Kang, M.H.2    Askew, C.3    Kang, R.4    Sanders, S.S.5    Wan, J.6    Davis, N.G.7    Hayden, M.R.8
  • 29
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Y. Kanai, and M.A. Hediger Primary structure and functional characterization of a high-affinity glutamate transporter Nature 360 1992 467 471
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 30
    • 0035725688 scopus 로고    scopus 로고
    • Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction
    • H. Katagiri, K. Tanaka, and T. Manabe Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction Eur. J. Neurosci. 14 2001 547 553
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 547-553
    • Katagiri, H.1    Tanaka, K.2    Manabe, T.3
  • 31
    • 26944493785 scopus 로고    scopus 로고
    • Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1
    • E. Krizman-Genda, M.I. Gonzalez, O. Zelenaia, and M.B. Robinson Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1 Neuropharmacology 49 2005 872 882
    • (2005) Neuropharmacology , vol.49 , pp. 872-882
    • Krizman-Genda, E.1    Gonzalez, M.I.2    Zelenaia, O.3    Robinson, M.B.4
  • 32
    • 77950682093 scopus 로고    scopus 로고
    • Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease
    • X. Li, A. Valencia, E. Sapp, N. Masso, J. Alexander, P. Reeves, K.B. Kegel, N. Aronin, and M. Difiglia Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease J. Neurosci. 30 2010 4552 4561
    • (2010) J. Neurosci. , vol.30 , pp. 4552-4561
    • Li, X.1    Valencia, A.2    Sapp, E.3    Masso, N.4    Alexander, J.5    Reeves, P.6    Kegel, K.B.7    Aronin, N.8    Difiglia, M.9
  • 33
    • 61449254617 scopus 로고    scopus 로고
    • Synaptic localization of GLT-1a in the rat somatic sensory cortex
    • M. Melone, M. Bellesi, and F. Conti Synaptic localization of GLT-1a in the rat somatic sensory cortex Glia 57 2009 108 117
    • (2009) Glia , vol.57 , pp. 108-117
    • Melone, M.1    Bellesi, M.2    Conti, F.3
  • 34
    • 2942590481 scopus 로고    scopus 로고
    • Interactions between glutamate transporters and metabotropic glutamate receptors at excitatory synapses in the cerebellar cortex
    • T.S. Otis, G. Brasnjo, J.A. Dzubay, and M. Pratap Interactions between glutamate transporters and metabotropic glutamate receptors at excitatory synapses in the cerebellar cortex Neurochem. Int. 45 2004 537 544
    • (2004) Neurochem. Int. , vol.45 , pp. 537-544
    • Otis, T.S.1    Brasnjo, G.2    Dzubay, J.A.3    Pratap, M.4
  • 35
    • 66049094472 scopus 로고    scopus 로고
    • The four major N- and C-terminal splice variants of the excitatory amino acid transporter GLT-1 form cell surface homomeric and heteromeric assemblies
    • E. Peacey, C.C. Miller, J. Dunlop, and M. Rattray The four major N- and C-terminal splice variants of the excitatory amino acid transporter GLT-1 form cell surface homomeric and heteromeric assemblies Mol. Pharmacol. 75 2009 1062 1073
    • (2009) Mol. Pharmacol. , vol.75 , pp. 1062-1073
    • Peacey, E.1    Miller, C.C.2    Dunlop, J.3    Rattray, M.4
  • 39
    • 4444301113 scopus 로고    scopus 로고
    • A new GLT-1 splice variant: Cloning and immunolocalization of GLT-1c in the mammalian retina and brain
    • T. Rauen, M. Wiessner, R. Sullivan, A. Lee, and D.V. Pow A new GLT-1 splice variant: cloning and immunolocalization of GLT-1c in the mammalian retina and brain Neurochem. Int. 45 2004 1095 1106
    • (2004) Neurochem. Int. , vol.45 , pp. 1095-1106
    • Rauen, T.1    Wiessner, M.2    Sullivan, R.3    Lee, A.4    Pow, D.V.5
  • 41
    • 0031036195 scopus 로고    scopus 로고
    • Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors
    • M. Scanziani, P.A. Salin, K.E. Vogt, R.C. Malenka, and R.A. Nicoll Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors Nature 385 1997 630 634
    • (1997) Nature , vol.385 , pp. 630-634
    • Scanziani, M.1    Salin, P.A.2    Vogt, K.E.3    Malenka, R.C.4    Nicoll, R.A.5
  • 42
    • 0035369252 scopus 로고    scopus 로고
    • The uptake of cysteine in cultured primary astrocytes and neurons
    • G. Shanker, J.W. Allen, L.A. Mutkus, and M. Aschner The uptake of cysteine in cultured primary astrocytes and neurons Brain Res. 902 2001 156 163
    • (2001) Brain Res. , vol.902 , pp. 156-163
    • Shanker, G.1    Allen, J.W.2    Mutkus, L.A.3    Aschner, M.4
  • 44
    • 4444357239 scopus 로고    scopus 로고
    • Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice
    • W. Stoffel, R. Korner, D. Wachtmann, and B.U. Keller Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice Brain Res. Mol. Brain Res. 128 2004 170 181
    • (2004) Brain Res. Mol. Brain Res. , vol.128 , pp. 170-181
    • Stoffel, W.1    Korner, R.2    Wachtmann, D.3    Keller, B.U.4
  • 45
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain
    • T. Storck, S. Schulte, K. Hofmann, and W. Stoffel Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain Proc. Natl. Acad. Sci. USA 89 1992 10955 10959
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10955-10959
    • Storck, T.1    Schulte, S.2    Hofmann, K.3    Stoffel, W.4
  • 46
    • 0029088203 scopus 로고
    • Pre- and postsynaptic determinants of EPSC waveform at cerebellar climbing fiber and parallel fiber to Purkinje cell synapses
    • M. Takahashi, Y. Kovalchuk, and D. Attwell Pre- and postsynaptic determinants of EPSC waveform at cerebellar climbing fiber and parallel fiber to Purkinje cell synapses J. Neurosci. 15 1995 5693 5702
    • (1995) J. Neurosci. , vol.15 , pp. 5693-5702
    • Takahashi, M.1    Kovalchuk, Y.2    Attwell, D.3
  • 48
    • 0031867231 scopus 로고    scopus 로고
    • Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways
    • J. Velier, M. Kim, C. Schwarz, T.W. Kim, E. Sapp, K. Chase, N. Aronin, and M. DiFiglia Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways Exp. Neurol. 152 1998 34 40
    • (1998) Exp. Neurol. , vol.152 , pp. 34-40
    • Velier, J.1    Kim, M.2    Schwarz, C.3    Kim, T.W.4    Sapp, E.5    Chase, K.6    Aronin, N.7    Difiglia, M.8
  • 49
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • C.J. Vlahos, W.F. Matter, K.Y. Hui, and R.F. Brown A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4- one (LY294002) J. Biol. Chem. 269 1994 5241 5248
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 51
    • 0041475740 scopus 로고    scopus 로고
    • Decrease in glial glutamate transporter variants and excitatory amino acid receptor down-regulation in a murine model of ALS-PDC
    • J.M. Wilson, I. Khabazian, D.V. Pow, U.K. Craig, and C.A. Shaw Decrease in glial glutamate transporter variants and excitatory amino acid receptor down-regulation in a murine model of ALS-PDC Neuromolecular Med. 3 2003 105 118
    • (2003) Neuromolecular Med. , vol.3 , pp. 105-118
    • Wilson, J.M.1    Khabazian, I.2    Pow, D.V.3    Craig, U.K.4    Shaw, C.A.5
  • 52
    • 0036566675 scopus 로고    scopus 로고
    • Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin
    • A. Wyttenbach, O. Sauvageot, J. Carmichael, C. Diaz-Latoud, A.P. Arrigo, and D.C. Rubinsztein Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin Hum. Mol. Genet. 11 2002 1137 1151
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1137-1151
    • Wyttenbach, A.1    Sauvageot, O.2    Carmichael, J.3    Diaz-Latoud, C.4    Arrigo, A.P.5    Rubinsztein, D.C.6
  • 54
    • 0029891464 scopus 로고    scopus 로고
    • Interaction of l-cysteine with a human excitatory amino acid transporter
    • N. Zerangue, and M.P. Kavanaugh Interaction of l-cysteine with a human excitatory amino acid transporter J. Physiol. 493 Pt 2 1996 419 423
    • (1996) J. Physiol. , vol.493 , Issue.PART 2 , pp. 419-423
    • Zerangue, N.1    Kavanaugh, M.P.2


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