Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance

Journal of Biological Chemistry

Volumn 283, Issue 30, 2008, Pages 21220-21229

  Inoue, Noriyuki ^a   Yahagi, Naoya ^a   Yamamoto, Takashi ^a   Ishikawa, Mayumi ^a   Watanabe, Kazuhisa ^a   Matsuzaka, Takashi ^a   Nakagawa, Yoshimi ^a   Takeuchi, Yoshinori ^a   Kobayashi, Kazuto ^a   Takahashi, Akimitsu ^a   Suzuki, Hiroaki ^a   Hasty, Alyssa H ^b   Toyoshima, Hideo ^a   Yamada, Nobuhiro ^a   Shimano, Hitoshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; ECOLOGY; FIBROBLASTS; HORMONES; INSULIN; NUCLEIC ACIDS; NUTRITION; PATHOLOGY; RNA;

ADIPOCYTE; ADIPOCYTE DIFFERENTIATIONS; ADIPOCYTE HYPERTROPHIES; ADIPOCYTES; ADIPOSE TISSUES; APOPTOSIS; EMBRYONIC FIBROBLASTS; HIGH ENERGIES; IN VITRO; IN-VIVO; INSULIN RESISTANCES; INSULIN SENSITIVITIES; KINASE INHIBITORS; OBESE MOUSE; PATHOPHYSIOLOGICAL;

MOLECULAR WEIGHT;

CYCLIN DEPENDENT KINASE INHIBITOR; INSULIN; PROTEIN P21; RNA; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN P53;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELL PROTECTION; CELL STRAIN 3T3; CONTROLLED STUDY; EMBRYO CELL; EPIDIDYMIS; FAT INTAKE; FIBROBLAST; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CELL PROLIFERATION; CYTOLOGY; HYPERTROPHY; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

MUS;

3T3 CELLS; ADIPOCYTES; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HYPERTROPHY; INSULIN RESISTANCE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; OBESITY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 51049095727     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801824200     Document Type: Article

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