Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c

Journal of Experimental and Clinical Cancer Research

Volumn 30, Issue 1, 2011, Pages

  Ling, Qi ^a   Xu, Xiao ^a   Wei, Xuyong ^a   Wang, Weibing ^a   Zhou, Bin ^a   Wang, Bei ^a   Zheng, Shusen ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CYTOCHROME C; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; LIVIN; NEURONAL APOPTOSIS INHIBITORY PROTEIN; OXYMATRINE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BID; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS; ALKALOID; ANTINEOPLASTIC AGENT; INHIBITOR OF APOPTOSIS PROTEIN; MESSENGER RNA; QUINOLIZINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL DESTRUCTION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CELL GROWTH; GENETICS; METABOLISM; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE;

ALKALOIDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; QUINOLIZINES; RNA, MESSENGER;

EID: 79959641621     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-30-66     Document Type: Article

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