Determination of oxymatrine and its activemetabolitematrine in human plasma after administration of oxymatrine oral solution by high-performance liquid chromatography coupled with mass spectrometry

Fitoterapia

Volumn 89, Issue 1, 2013, Pages 271-277

  Fan, Ruoxi ^a   Liu, Ran ^a   Ma, Ran ^a   Bi, Kaishun ^a   Li, Qing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

LC MS; Matrine; Oxymatrine; Oxymatrine oral solution; Pharmacokinetics

Indexed keywords

MATRINE; OXYMATRINE; ALKALOID; HERBACEOUS AGENT; QUINOLIZINE DERIVATIVE;

ARTICLE; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION MONITORING; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MASS SPECTROMETER; MASS SPECTROMETRY; METABOLITE; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; BLOOD; CALIBRATION; CHEMISTRY; HUMAN; METABOLISM; ORAL DRUG ADMINISTRATION; PROCEDURES; REPRODUCIBILITY; SOPHORA; VALIDATION STUDY; LC-MS; METHODOLOGY; OXYMATRINE ORAL SOLUTION; PHARMACOKINETICS;

ADMINISTRATION, ORAL; ALKALOIDS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; HUMANS; MASS SPECTROMETRY; QUALITY CONTROL; QUINOLIZINES; REPRODUCIBILITY OF RESULTS; SOPHORA;

LC-MS; MATRINE; OXYMATRINE; OXYMATRINE ORAL SOLUTION; PHARMACOKINETICS;

EID: 84885090630     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2013.05.024     Document Type: Article

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