메뉴 건너뛰기




Volumn 13, Issue 3, 2014, Pages 418-428

Does parkinson's disease and type-2 diabetes mellitus present common pathophysiological mechanisms and treatments?

Author keywords

Dopamine; Parkinson's disease; Peroxisome proliferator activated receptor ; Treatment; Type 2 diabetes mellitus

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DIPEPTIDYL PEPTIDASE IV; DOPAMINE; DOPAMINE TRANSPORTER; GLIBENCLAMIDE; GLUCAGON LIKE PEPTIDE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 6; OXIDOPAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PINACIDIL; PIOGLITAZONE; ROSIGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE 3 MONOOXYGENASE; VILDAGLIPTIN; GLUCOSE;

EID: 84904463268     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/18715273113126660155     Document Type: Review
Times cited : (48)

References (171)
  • 1
    • 84881243057 scopus 로고    scopus 로고
    • Sleep disturbances in Parkinson's disease: The contribution of dopamine in REM sleep regulation
    • Lima MM. Sleep disturbances in Parkinson's disease: The contribution of dopamine in REM sleep regulation. Sleep Med Rev 2013; 17: 367-75.
    • (2013) Sleep Med Rev , vol.17 , pp. 367-375
    • Lima, M.M.1
  • 2
    • 0031875831 scopus 로고    scopus 로고
    • Drug-induced parkinsonism as a risk factor for Parkinson's disease: A historical cohort study in Olmsted County, Minnesota
    • Chabolla DR, Maraganore DM, Ahlskog JE, O'Brien PC, Rocca WA. Drug-induced parkinsonism as a risk factor for Parkinson's disease: a historical cohort study in Olmsted County, Minnesota. Mayo Clin Proc 1998; 73: 724-7.
    • (1998) Mayo Clin Proc , vol.73 , pp. 724-727
    • Chabolla, D.R.1    Maraganore, D.M.2    Ahlskog, J.E.3    O'Brien, P.C.4    Rocca, W.A.5
  • 3
    • 67849109838 scopus 로고    scopus 로고
    • Diabetes mellitus and druginduced Parkinsonism: A case-control study
    • Ma HI, Kim JH, Chu MK, et al. Diabetes mellitus and druginduced Parkinsonism: a case-control study. J Neurol Sci 2009; 284: 140-3.
    • (2009) J Neurol Sci , vol.284 , pp. 140-143
    • Ma, H.I.1    Kim, J.H.2    Chu, M.K.3
  • 4
    • 0025847968 scopus 로고
    • Insulin receptors in the central nervous system: Localization, signalling mechanisms and functional aspects
    • Unger JW, Livingston JN, Moss AM. Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects. Prog Neurobiol 1991; 36: 343-62.
    • (1991) Prog Neurobiol , vol.36 , pp. 343-362
    • Unger, J.W.1    Livingston, J.N.2    Moss, A.M.3
  • 5
    • 0025808620 scopus 로고
    • Immunohistochemical localization of insulin receptors and phosphotyrosine in the brainstem of the adult rat
    • Unger JW, Moss AM, Livingston JN. Immunohistochemical localization of insulin receptors and phosphotyrosine in the brainstem of the adult rat. Neuroscience 1991; 42: 853-61.
    • (1991) Neuroscience , vol.42 , pp. 853-861
    • Unger, J.W.1    Moss, A.M.2    Livingston, J.N.3
  • 6
    • 77958072667 scopus 로고    scopus 로고
    • PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease
    • Zheng B, Liao Z, Locascio JJ, et al. PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med 2010; 2: 52-73.
    • (2010) Sci Transl Med , vol.2 , pp. 52-73
    • Zheng, B.1    Liao, Z.2    Locascio, J.J.3
  • 7
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's disease is type 3 diabetesevidence reviewed
    • de la Monte SM, Wands JR. Alzheimer's disease is type 3 diabetesevidence reviewed. J Diabetes Sci Technol 2008; 2: 1101-13.
    • (2008) J Diabetes Sci Technol , vol.2 , pp. 1101-1113
    • de la Monte, S.M.1    Wands, J.R.2
  • 8
    • 33847080728 scopus 로고    scopus 로고
    • AMP-activated protein kinase in metabolic control and insulin signaling
    • Towler MC, Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 2007; 100: 328-41.
    • (2007) Circ Res , vol.100 , pp. 328-341
    • Towler, M.C.1    Hardie, D.G.2
  • 10
    • 0347761283 scopus 로고    scopus 로고
    • Diabetesinduced biochemical changes in central and peripheral catecholaminergic systems
    • Gallego M, Setien R, Izquierdo MJ, Casis O, Casis E. Diabetesinduced biochemical changes in central and peripheral catecholaminergic systems. Physiol Res 2003; 52: 735-41.
    • (2003) Physiol Res , vol.52 , pp. 735-741
    • Gallego, M.1    Setien, R.2    Izquierdo, M.J.3    Casis, O.4    Casis, E.5
  • 11
    • 0033048184 scopus 로고    scopus 로고
    • Intracerebroventricular administration of bromocriptine ameliorates the insulinresistant/ glucose-intolerant state in hamsters
    • Luo S, Liang Y, Cincotta AH. Intracerebroventricular administration of bromocriptine ameliorates the insulinresistant/ glucose-intolerant state in hamsters. Neuroendocrinology 1999; 69: 160-6.
    • (1999) Neuroendocrinology , vol.69 , pp. 160-166
    • Luo, S.1    Liang, Y.2    Cincotta, A.H.3
  • 12
    • 0028230437 scopus 로고
    • Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra
    • Figlewicz DP, Szot P, Chavez M, Woods SC, Veith RC. Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra. Brain Res 1994; 644: 331-4.
    • (1994) Brain Res , vol.644 , pp. 331-334
    • Figlewicz, D.P.1    Szot, P.2    Chavez, M.3    Woods, S.C.4    Veith, R.C.5
  • 13
    • 0030583628 scopus 로고    scopus 로고
    • Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: A molecular study
    • Figlewicz DP, Brot MD, McCall AL, Szot P. Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study. Brain Res 1996; 736: 54-60.
    • (1996) Brain Res , vol.736 , pp. 54-60
    • Figlewicz, D.P.1    Brot, M.D.2    McCall, A.L.3    Szot, P.4
  • 14
    • 0030052817 scopus 로고    scopus 로고
    • Diabetes decreases limbic extracellular dopamine in rats
    • Murzi E, Contreras Q, Teneud L, et al. Diabetes decreases limbic extracellular dopamine in rats. Neurosci Lett 1996; 202: 141-4.
    • (1996) Neurosci Lett , vol.202 , pp. 141-144
    • Murzi, E.1    Contreras, Q.2    Teneud, L.3
  • 15
    • 0015504340 scopus 로고
    • Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism
    • Sirtori CR, Bolme P, Azarnoff DL. Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism. N Engl J Med 1972; 287: 729-33.
    • (1972) N Engl J Med , vol.287 , pp. 729-733
    • Sirtori, C.R.1    Bolme, P.2    Azarnoff, D.L.3
  • 16
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • Craft S, Watson GS. Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol 2004; 3: 169-78.
    • (2004) Lancet Neurol , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 17
    • 0035010337 scopus 로고    scopus 로고
    • Matching Treatment to Pathophysiology in type 2 Diabetes
    • Gerich J. Matching Treatment to Pathophysiology in type 2 Diabetes. Clin Therap 2001; 23: 14.
    • (2001) Clin Therap , vol.23 , pp. 14
    • Gerich, J.1
  • 18
    • 34548835478 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus: Epidemiology, pathophysiology, unmet needs and therapeutical perspectives
    • Virally M, Blicklé JF, Girard J, Halimi S, Simon D, Guillausseau PJ. Type 2 diabetes mellitus: epidemiology, pathophysiology, unmet needs and therapeutical perspectives. Diab Metab 2007; 33: 231-44.
    • (2007) Diab Metab , vol.33 , pp. 231-244
    • Virally, M.1    Blicklé, J.F.2    Girard, J.3    Halimi, S.4    Simon, D.5    Guillausseau, P.J.6
  • 19
    • 0024026298 scopus 로고
    • Lecture Lilly. The triumvirate: Beta cell, muscle, liver. A collusion responsible for NIDDM
    • DeFronzo RA. Lecture Lilly. The triumvirate: beta cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988; 37: 667-87.
    • (1988) Diabetes , vol.37 , pp. 667-687
    • Defronzo, R.A.1
  • 20
    • 19944390213 scopus 로고    scopus 로고
    • Pathogenesis of Type 2 Diabetes Mellitus
    • Leahy JL. Pathogenesis of Type 2 Diabetes Mellitus. Arch Med Res 2005; 36: 197-209.
    • (2005) Arch Med Res , vol.36 , pp. 197-209
    • Leahy, J.L.1
  • 21
    • 0030724591 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus: Metabolic and molecular implications for identifying diabetes genes
    • DeFronzo RA. Pathogenesis of type 2 diabetes mellitus: metabolic and molecular implications for identifying diabetes genes. Diabetes 1997; 5: 177-269.
    • (1997) Diabetes , vol.5 , pp. 177-269
    • Defronzo, R.A.1
  • 22
    • 4143151942 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus
    • DeFronzo RA. Pathogenesis of type 2 diabetes mellitus. Med Clin North Am 2004; 88: 787-835.
    • (2004) Med Clin North Am , vol.88 , pp. 787-835
    • Defronzo, R.A.1
  • 23
    • 0024392514 scopus 로고
    • Glucose and free fatty acid metabolism in non-insulin dependent diabetes mellitus. Evidence for multiple sites of insulin resistance
    • Groop LB, Del Prato RC, Ratheiser S, et al. Glucose and free fatty acid metabolism in non-insulin dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest 1989; 84: 205-15.
    • (1989) J Clin Invest , vol.84 , pp. 205-215
    • Groop, L.B.1    Del Prato, R.C.2    Ratheiser, S.3
  • 24
    • 1442352339 scopus 로고    scopus 로고
    • Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach
    • Bays H. Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach. J Clin Endocrinol Metab 2004; 89: 463-78.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 463-478
    • Bays, H.1
  • 25
    • 0031014830 scopus 로고    scopus 로고
    • Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
    • Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997; 46: 3-10.
    • (1997) Diabetes , vol.46 , pp. 3-10
    • Boden, G.1
  • 26
    • 0842313004 scopus 로고    scopus 로고
    • Decreased Plasma Adiponectin Concentrations Are Closely Related to Hepatic Fat Content and Hepatic Insulin Resistance in Pioglitazone-Treated Type 2 Diabetic Patients
    • Bajaj M. Decreased Plasma Adiponectin Concentrations Are Closely Related to Hepatic Fat Content and Hepatic Insulin Resistance in Pioglitazone-Treated Type 2 Diabetic Patients. J Clin Endocrinol Metab 2004; 89: 200-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 200-206
    • Bajaj, M.1
  • 27
    • 77957201362 scopus 로고    scopus 로고
    • Obesity and diabetes: The links and common approaches
    • Haslam D. Obesity and diabetes: the links and common approaches. Prim Care Diabet 2010; 4: 105-12.
    • (2010) Prim Care Diabet , vol.4 , pp. 105-112
    • Haslam, D.1
  • 28
    • 79958041870 scopus 로고    scopus 로고
    • Is it Time to Seriously Target Obesity to Prevent and Control Diabetes?
    • Sharma AM, Padwal R, Karmali S, Birch WD. Is it Time to Seriously Target Obesity to Prevent and Control Diabetes? Can J Diab 2011; 35: 129-35.
    • (2011) Can J Diab , vol.35 , pp. 129-135
    • Sharma, A.M.1    Padwal, R.2    Karmali, S.3    Birch, W.D.4
  • 29
    • 75149194772 scopus 로고    scopus 로고
    • Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities
    • Yorek WISaMA
    • Yorek WISaMA. Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities. Antioxid Redox Signal 2010; 12: 537-77.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 537-577
  • 30
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes
    • Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes. Diabetes 2002; 51: 2944-50.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 31
    • 2342505286 scopus 로고    scopus 로고
    • Alteration in insulin action: Role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling
    • Tanti JF, Gual P, Grémeaux T, et al. Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling. Ann Endocrinol 2004; 65: 43-8.
    • (2004) Ann Endocrinol , vol.65 , pp. 43-48
    • Tanti, J.F.1    Gual, P.2    Grémeaux, T.3
  • 32
    • 0035511730 scopus 로고    scopus 로고
    • Skeletal Muscle Insulin Resistance in Normoglycemic Subjects With a Strong Family History of Type 2 Diabetes Is Associated With Decreased Insulin-Stimulated Insulin Receptor Substrate-1 Tyrosine Phosphorylation
    • Pratipanawatr W, Pratipanawatr T, Cusi K, et al. Skeletal Muscle Insulin Resistance in Normoglycemic Subjects With a Strong Family History of Type 2 Diabetes Is Associated With Decreased Insulin-Stimulated Insulin Receptor Substrate-1 Tyrosine Phosphorylation. Diabetes 2001; 50: 2572-8.
    • (2001) Diabetes , vol.50 , pp. 2572-2578
    • Pratipanawatr, W.1    Pratipanawatr, T.2    Cusi, K.3
  • 33
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle
    • Cusi K, Maezono K, Osman A, et al. Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle. J Clin Invest 2000; 105: 311-20.
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3
  • 34
    • 0033553462 scopus 로고    scopus 로고
    • Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes
    • Jonas JCS, Hasenkamp W, Ilkova H, et al. Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes. J Biol Chem 1999; 274: 14112-21.
    • (1999) J Biol Chem , vol.274 , pp. 14112-14121
    • Jonas, J.C.S.1    Hasenkamp, W.2    Ilkova, H.3
  • 35
    • 0032898667 scopus 로고    scopus 로고
    • Fatty acids, lipotoxicity and insulin secretion
    • McGarry JD, Dobbins RL. Fatty acids, lipotoxicity and insulin secretion. Diabetologia 1999; 42: 128-38.
    • (1999) Diabetologia , vol.42 , pp. 128-138
    • McGarry, J.D.1    Dobbins, R.L.2
  • 36
  • 37
    • 64649104158 scopus 로고    scopus 로고
    • From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
    • DeFronzo RA. From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus. Diabetes 2009; 58: 773-95.
    • (2009) Diabetes , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 38
    • 47249154297 scopus 로고    scopus 로고
    • Abnormalities in insulin secretion in type 2 diabetes mellitus
    • Guillausseau PJ, Meas T, Virally M, et al. Abnormalities in insulin secretion in type 2 diabetes mellitus. Diab Metab 2008; 34: S43-8.
    • (2008) Diab Metab , vol.34
    • Guillausseau, P.J.1    Meas, T.2    Virally, M.3
  • 39
    • 0025291474 scopus 로고
    • A comparison of brain glucose metabolism in diabetes as measured by positron emission tomography or by arteriovenous techniques
    • Grill V. A comparison of brain glucose metabolism in diabetes as measured by positron emission tomography or by arteriovenous techniques. Ann Med 1990; 22: 171-5.
    • (1990) Ann Med , vol.22 , pp. 171-175
    • Grill, V.1
  • 40
    • 0023090430 scopus 로고
    • Regulation of hepatic glucose metabolism in humans
    • DeFronzo RA, Ferrannini E. Regulation of hepatic glucose metabolism in humans. Diab Metab Rev 1987; 3: 415-59.
    • (1987) Diab Metab Rev , vol.3 , pp. 415-459
    • Defronzo, R.A.1    Ferrannini, E.2
  • 41
    • 0033126490 scopus 로고    scopus 로고
    • Control of Glucose Uptake and Release by the Liver In Vivo
    • Cherrington AD. Control of Glucose Uptake and Release by the Liver In Vivo. Diabetes 1999; 48: 1198-214.
    • (1999) Diabetes , vol.48 , pp. 1198-1214
    • Cherrington, A.D.1
  • 42
    • 0025066579 scopus 로고
    • Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM
    • Mitrakou AK, Veneman D, Jensen T, et al. Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM. Diabetes 1990; 39: 1381-90.
    • (1990) Diabetes , vol.39 , pp. 1381-1390
    • Mitrakou, A.K.1    Veneman, D.2    Jensen, T.3
  • 43
    • 0024507794 scopus 로고
    • Fasting hyperglycemia in non-insulindependent diabetes mellitus: Contributions of excessive hepatic glucose production and impaired tissue glucose uptake
    • DeFronzo RA, Ferrannini E, Simonson DC. Fasting hyperglycemia in non-insulindependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism 1989; 38: 387-95.
    • (1989) Metabolism , vol.38 , pp. 387-395
    • Defronzo, R.A.1    Ferrannini, E.2    Simonson, D.C.3
  • 44
    • 0033890616 scopus 로고    scopus 로고
    • Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: A quantitative study
    • Gastaldelli A, Baldi S, Pettiti M, et al. Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study. Diabetes 2000; 49: 1367-73.
    • (2000) Diabetes , vol.49 , pp. 1367-1373
    • Gastaldelli, A.1    Baldi, S.2    Pettiti, M.3
  • 45
    • 0034034229 scopus 로고    scopus 로고
    • Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes
    • Clore JN, Stillman J, Sugerman H. Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes. Diabetes 2000; 49: 969-74.
    • (2000) Diabetes , vol.49 , pp. 969-974
    • Clore, J.N.1    Stillman, J.2    Sugerman, H.3
  • 46
    • 0023271871 scopus 로고
    • Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry
    • Werther GA, Hogg A, Oldfield BJ, et al. Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry. Endocrinology 1987; 121: 1562-70.
    • (1987) Endocrinology , vol.121 , pp. 1562-1570
    • Werther, G.A.1    Hogg, A.2    Oldfield, B.J.3
  • 47
    • 0022510796 scopus 로고
    • Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas
    • Hill JM Lesniak MA, Pert CB, Roth J. Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neuroscience 1986; 17: 1127-38.
    • (1986) Neuroscience , vol.17 , pp. 1127-1138
    • Hill, J.M.1    Lesniak, M.A.2    Pert, C.B.3    Roth, J.4
  • 48
    • 0025947341 scopus 로고
    • Food Intake and Serum Insulin Responses to Intraventricular Infusions of Insulin and IGF-I
    • Foster LA, Ames NK, Emery RS. Food Intake and Serum Insulin Responses to Intraventricular Infusions of Insulin and IGF-I. Physiol Behav 1990; 50: 745-9.
    • (1990) Physiol Behav , vol.50 , pp. 745-749
    • Foster, L.A.1    Ames, N.K.2    Emery, R.S.3
  • 49
    • 0034703229 scopus 로고    scopus 로고
    • Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
    • Brüning JC, Gautam D, Burks DJ, et al. Role of Brain Insulin Receptor in Control of Body Weight and Reproduction. Science 2000; 289: 2122-5.
    • (2000) Science , vol.289 , pp. 2122-2125
    • Brüning, J.C.1    Gautam, D.2    Burks, D.J.3
  • 50
    • 79951953438 scopus 로고    scopus 로고
    • Hypothalamic neurosphere progenitor cells in low birth-weight rat newborns: Neurotrophic effects of leptin and insulin
    • Desai M, Li T, Ross MG. Hypothalamic neurosphere progenitor cells in low birth-weight rat newborns: Neurotrophic effects of leptin and insulin. Brain Res 2011; 1378: 29-42.
    • (2011) Brain Res , vol.1378 , pp. 29-42
    • Desai, M.1    Li, T.2    Ross, M.G.3
  • 51
    • 0023607908 scopus 로고
    • Insulin stimulates choline acetyltransferase activity in cultured embryonic chickens retina neurons
    • Kyriakis JM, Hausman RE, Peterson SW. Insulin stimulates choline acetyltransferase activity in cultured embryonic chickens retina neurons. Proc Natl Acad Sci USA 1987; 84: 7463-7.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7463-7467
    • Kyriakis, J.M.1    Hausman, R.E.2    Peterson, S.W.3
  • 52
    • 0025265681 scopus 로고
    • Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II
    • Knusel B, Michel PP, Schwaber JS, Hefti F. Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II. J Neurosci 1990; 10: 558-70.
    • (1990) J Neurosci , vol.10 , pp. 558-570
    • Knusel, B.1    Michel, P.P.2    Schwaber, J.S.3    Hefti, F.4
  • 53
    • 0020661448 scopus 로고
    • Effect of insulin on central catecholamines
    • Sauter A, Goldstein M, Engel J, Ueta K. Effect of insulin on central catecholamines. Brain Res 1983; 260: 330-3.
    • (1983) Brain Res , vol.260 , pp. 330-333
    • Sauter, A.1    Goldstein, M.2    Engel, J.3    Ueta, K.4
  • 54
    • 0033197996 scopus 로고    scopus 로고
    • The Insulin Receptor Tyrosine Kinase Substrate p58/53 and the Insulin Receptor Are Components of CNS Synapses
    • Abbott MA, Wells DG, Fallon JR. The Insulin Receptor Tyrosine Kinase Substrate p58/53 and the Insulin Receptor Are Components of CNS Synapses. J Neurosci 1999; 19: 7300-8.
    • (1999) J Neurosci , vol.19 , pp. 7300-7308
    • Abbott, M.A.1    Wells, D.G.2    Fallon, J.R.3
  • 56
    • 64549087258 scopus 로고    scopus 로고
    • Human cerebral neuropathology of Type 2 diabetes mellitus
    • Nelson PT, Smith CD, Abner EA, et al. Human cerebral neuropathology of Type 2 diabetes mellitus. Biochim Biophys Acta 2009; 1792: 454-69.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 454-469
    • Nelson, P.T.1    Smith, C.D.2    Abner, E.A.3
  • 57
    • 0034333018 scopus 로고    scopus 로고
    • Cognition and synaptic plasticity in diabetes mellitus
    • Gispen WH, Biessels GJ. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 2000; 23: 542-9.
    • (2000) Trends Neurosci , vol.23 , pp. 542-549
    • Gispen, W.H.1    Biessels, G.J.2
  • 58
    • 0025667752 scopus 로고
    • Cognitive function in diabetes mellitus
    • Richardson JT. Cognitive function in diabetes mellitus. Neurosci Biobehav Rev 1990; 14: 385-8.
    • (1990) Neurosci Biobehav Rev , vol.14 , pp. 385-388
    • Richardson, J.T.1
  • 59
    • 84857788978 scopus 로고    scopus 로고
    • Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation
    • Correia SC, Santos RX, Carvalho C, et al. Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation. Brain Res 2012; 1441: 64-78.
    • (2012) Brain Res , vol.1441 , pp. 64-78
    • Correia, S.C.1    Santos, R.X.2    Carvalho, C.3
  • 60
    • 64249129005 scopus 로고    scopus 로고
    • Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease
    • Zhao WQ, Townsend M. Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease. Biochim Biophys Acta 2009; 1792: 482-96.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 482-496
    • Zhao, W.Q.1    Townsend, M.2
  • 61
    • 36448936053 scopus 로고    scopus 로고
    • Common pathological processes in Alzheimer disease and type 2 diabetes: A review
    • Li L, Hölscher C. Common pathological processes in Alzheimer disease and type 2 diabetes: A review. Brain Res Rev 2007; 56: 384-402.
    • (2007) Brain Res Rev , vol.56 , pp. 384-402
    • Li, L.1    Hölscher, C.2
  • 62
    • 67149103937 scopus 로고    scopus 로고
    • Diabetes mellitus and cerebrovascular disease: Which are the actual data?
    • Hatzitolios AI, Didangelos TP, Zantidis AT, et al. Diabetes mellitus and cerebrovascular disease: which are the actual data? J Diab Complic 2009; 23: 283-96.
    • (2009) J Diab Complic , vol.23 , pp. 283-296
    • Hatzitolios, A.I.1    Didangelos, T.P.2    Zantidis, A.T.3
  • 63
    • 0028149498 scopus 로고
    • Diabetes mellitus and cerebral vascular disease
    • Kameyama M, Fushimi H, Udaka F. Diabetes mellitus and cerebral vascular disease. Diab Res Clin Prac 1994; 24: 205-8.
    • (1994) Diab Res Clin Prac , vol.24 , pp. 205-208
    • Kameyama, M.1    Fushimi, H.2    Udaka, F.3
  • 64
    • 80755128986 scopus 로고    scopus 로고
    • Comparison of carotid and cerebrovascular disease between diabetic and non-diabetic patients using dual-source CT
    • He C, Yang ZG, Chu ZG, et al. Comparison of carotid and cerebrovascular disease between diabetic and non-diabetic patients using dual-source CT. Eur J Radiol 2011; 80: e361-5.
    • (2011) Eur J Radiol , vol.80
    • He, C.1    Yang, Z.G.2    Chu, Z.G.3
  • 66
    • 0015029469 scopus 로고
    • Glucose, insulin and free fatty acid metabolism in Parkinson's Disease treated with L-dopa
    • Van Woert MH, Mueller PS. Glucose, insulin and free fatty acid metabolism in Parkinson's Disease treated with L-dopa. Clin Pharm Therap 1971; 12: 360-7.
    • (1971) Clin Pharm Therap , vol.12 , pp. 360-367
    • van Woert, M.H.1    Mueller, P.S.2
  • 67
    • 0015145828 scopus 로고
    • Endocrine function and glucose metabolism in patients with Parkinson's Disease and their alteration by L-dopa
    • Boyd AE 3rd, Lebovitz HE, Feldman JM. Endocrine function and glucose metabolism in patients with Parkinson's Disease and their alteration by L-dopa. J Clin Endocrinol Metab 1971; 33: 829-37.
    • (1971) J Clin Endocrinol Metab , vol.33 , pp. 829-837
    • Boyd III, A.E.1    Lebovitz, H.E.2    Feldman, J.M.3
  • 68
    • 0016318795 scopus 로고
    • Glucose intolerance in parkinson's disease
    • Lipman IJ, Boykin ME, Flora RE. Glucose intolerance in parkinson's disease. J Chron Dis 1974; 27: 573-9.
    • (1974) J Chron Dis , vol.27 , pp. 573-579
    • Lipman, I.J.1    Boykin, M.E.2    Flora, R.E.3
  • 69
    • 67849109838 scopus 로고    scopus 로고
    • Diabetes mellitus and druginduced parkinsonism: A case-control study
    • Ma HI, Kim JH, Chu MK, et al. Diabetes mellitus and druginduced parkinsonism: A case-control study. J Neurol Sci 2009; 284: 140-3.
    • (2009) J Neurol Sci , vol.284 , pp. 140-143
    • Ma, H.I.1    Kim, J.H.2    Chu, M.K.3
  • 70
    • 79957707210 scopus 로고    scopus 로고
    • Does deep brain stimulation of the subthalamic nucleus induce metabolic syndrome in Parkinson's disease?
    • Rieu I, Pereira B, Derost P, et al. Does deep brain stimulation of the subthalamic nucleus induce metabolic syndrome in Parkinson's disease? e-SPEN Eur J Clin Nutr Metab 2011; 6: e126-30.
    • (2011) E-SPEN Eur J Clin Nutr Metab , vol.6
    • Rieu, I.1    Pereira, B.2    Derost, P.3
  • 71
    • 0030047594 scopus 로고    scopus 로고
    • Insulin receptor mRNA in the substantia nigra in Parkinson's disease
    • Takahashi M, Yamada T, Tooyama I. Insulin receptor mRNA in the substantia nigra in Parkinson's disease. Neurosci Lett 1996; 204: 201-4.
    • (1996) Neurosci Lett , vol.204 , pp. 201-204
    • Takahashi, M.1    Yamada, T.2    Tooyama, I.3
  • 72
    • 0028344810 scopus 로고
    • Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease
    • Moroo I, Yamada T, Makino H, et al. Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease. Acta Neuropathol 1994; 87: 343-8.
    • (1994) Acta Neuropathol , vol.87 , pp. 343-348
    • Moroo, I.1    Yamada, T.2    Makino, H.3
  • 73
    • 36048933577 scopus 로고    scopus 로고
    • Hypertension, hypercholesterolemia, diabetes, and risk of Parkinson disease
    • Simon KC, Chen H, Schwarzschild M, Ascherio A. Hypertension, hypercholesterolemia, diabetes, and risk of Parkinson disease. Neurology 2007; 69: 1688-95.
    • (2007) Neurology , vol.69 , pp. 1688-1695
    • Simon, K.C.1    Chen, H.2    Schwarzschild, M.3    Ascherio, A.4
  • 74
    • 77952100141 scopus 로고    scopus 로고
    • Case-control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan
    • Miyake Y, Tanaka K, Fukushima W, et al. Case-control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan. J Neurol Sci 2010; 293: 82-6.
    • (2010) J Neurol Sci , vol.293 , pp. 82-86
    • Miyake, Y.1    Tanaka, K.2    Fukushima, W.3
  • 76
    • 0031426348 scopus 로고    scopus 로고
    • Effect of Diabetes Mellitus on the Permeability of the Blood-Brain Barrier to Insulin
    • Banks WA, Jaspan JB, Kastin AJ. Effect of Diabetes Mellitus on the Permeability of the Blood-Brain Barrier to Insulin. Peptides 1997; 18: 1577-84.
    • (1997) Peptides , vol.18 , pp. 1577-1584
    • Banks, W.A.1    Jaspan, J.B.2    Kastin, A.J.3
  • 77
    • 0027361094 scopus 로고
    • Saturable Transport of Insulin from Plasma into the Central Nervous System of Dogs In Vivo
    • Baura GD, Foster DM, Porte D Jr, et al. Saturable Transport of Insulin from Plasma into the Central Nervous System of Dogs In Vivo. J Clin Investig 1993; 92: 1824-30.
    • (1993) J Clin Investig , vol.92 , pp. 1824-1830
    • Baura, G.D.1    Foster, D.M.2    Porte Jr., D.3
  • 78
    • 0030583628 scopus 로고    scopus 로고
    • Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: A molecular study
    • Figlewicz DP, Brot MD, McCall AL, Szot P. Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study. Brain Res 1996; 736: 54-60.
    • (1996) Brain Res , vol.736 , pp. 54-60
    • Figlewicz, D.P.1    Brot, M.D.2    McCall, A.L.3    Szot, P.4
  • 79
    • 0019865177 scopus 로고
    • Dopamine receptor binding is increased in diabetic rats
    • Lozovsky D, Saller CF, Kopin IJ. Dopamine receptor binding is increased in diabetic rats. Science 1981; 214: 1031-3.
    • (1981) Science , vol.214 , pp. 1031-1033
    • Lozovsky, D.1    Saller, C.F.2    Kopin, I.J.3
  • 80
    • 82455175237 scopus 로고    scopus 로고
    • Effects of unilateral nigrostriatal dopamine depletion on peripheral glucose tolerance and insulin signaling in middle aged rats
    • Morris JK, Seim NB, Bomhoff GL, Geiger PC, Stanford JA. Effects of unilateral nigrostriatal dopamine depletion on peripheral glucose tolerance and insulin signaling in middle aged rats. Neurosci Lett 2011; 504: 219-22.
    • (2011) Neurosci Lett , vol.504 , pp. 219-222
    • Morris, J.K.1    Seim, N.B.2    Bomhoff, G.L.3    Geiger, P.C.4    Stanford, J.A.5
  • 81
    • 0021829406 scopus 로고
    • Permanent human parkinsonism due to 1-methyl-4-phenyl-1:2:3:6-tetrahydropyridine (MPTP): Seven cases
    • Ballard PA, Tetrud JW, Langston JW. Permanent human parkinsonism due to 1-methyl-4-phenyl-1:2:3:6-tetrahydropyridine (MPTP): seven cases. Neurology 1985; 35: 949-56.
    • (1985) Neurology , vol.35 , pp. 949-956
    • Ballard, P.A.1    Tetrud, J.W.2    Langston, J.W.3
  • 82
    • 0020680904 scopus 로고
    • Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston JW, Ballard P, Tetrud JW, Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983; 219: 979-80.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 83
    • 0025988085 scopus 로고
    • MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease
    • Gerlach M, Riederer P, Przuntek H, Youdim MB. MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease. Eur J Pharmacol 1991; 208: 273-86.
    • (1991) Eur J Pharmacol , vol.208 , pp. 273-286
    • Gerlach, M.1    Riederer, P.2    Przuntek, H.3    Youdim, M.B.4
  • 84
    • 30044442094 scopus 로고    scopus 로고
    • Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
    • Perier C. Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proc Natl Acad Sci USA 2005; 102: 19126-31.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 19126-19131
    • Perier, C.1
  • 85
    • 84864855869 scopus 로고    scopus 로고
    • Parkinson's disease, insulin resistance and novel agents of neuroprotection
    • Aviles-Olmos I, Limousin P, Lees A, Foltynie T. Parkinson's disease, insulin resistance and novel agents of neuroprotection. Brain 2013; 136(Pt 2): 374-84.
    • (2013) Brain , vol.136 , Issue.Pt 2 , pp. 374-384
    • Aviles-Olmos, I.1    Limousin, P.2    Lees, A.3    Foltynie, T.4
  • 86
    • 72149121292 scopus 로고    scopus 로고
    • Compromised respiratory adaptation and thermoregulation in aging and age-related diseases
    • Chan SL, Wei Z, Chigurupati S, Tu W. Compromised respiratory adaptation and thermoregulation in aging and age-related diseases. Ageing Res Rev 2010; 9: 20-40.
    • (2010) Ageing Res Rev , vol.9 , pp. 20-40
    • Chan, S.L.1    Wei, Z.2    Chigurupati, S.3    Tu, W.4
  • 87
    • 84860840558 scopus 로고    scopus 로고
    • Mitochondrial diseases
    • Schapira AHV. Mitochondrial diseases. Lancet 2012; 379: 1825-34.
    • (2012) Lancet , vol.379 , pp. 1825-1834
    • Schapira, A.H.V.1
  • 88
    • 84856415487 scopus 로고    scopus 로고
    • The role of mitochondria in insulin resistance and type 2 diabetes mellitus
    • Szendroedi J, Phielix E, Roden M. The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev Endocrinol 2011; 8(2): 92-103.
    • (2011) Nat Rev Endocrinol , vol.8 , Issue.2 , pp. 92-103
    • Szendroedi, J.1    Phielix, E.2    Roden, M.3
  • 89
    • 38449109568 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: Is there sufficient evidence for mechanism-based interventional therapy?
    • Tansey MG, Frank-Cannon TC, McCoy MK, et al. Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy? Front Biosci 2008; 13: 709-17.
    • (2008) Front Biosci , vol.13 , pp. 709-717
    • Tansey, M.G.1    Frank-Cannon, T.C.2    McCoy, M.K.3
  • 90
    • 0344305782 scopus 로고    scopus 로고
    • Insulin Signaling in Health and Disease
    • White MF. Insulin Signaling in Health and Disease. Science 2003; 302: 1710-1.
    • (2003) Science , vol.302 , pp. 1710-1711
    • White, M.F.1
  • 91
    • 0037477855 scopus 로고    scopus 로고
    • Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
    • Patti ME, Butte AJ, Crunkhorn S, et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 2003; 100: 8466-71.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8466-8471
    • Patti, M.E.1    Butte, A.J.2    Crunkhorn, S.3
  • 92
    • 69149087790 scopus 로고    scopus 로고
    • Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density
    • Barrès R, Osler ME, Yan J, et al. Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density. Cell Metab 2009; 10: 189-98.
    • (2009) Cell Metab , vol.10 , pp. 189-198
    • Barrès, R.1    Osler, M.E.2    Yan, J.3
  • 93
    • 79952303794 scopus 로고    scopus 로고
    • PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
    • Shin JH, Ko Han S, Kang H, et al. PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease. Cell 2011; 144: 689-702.
    • (2011) Cell , vol.144 , pp. 689-702
    • Shin, J.H.1    Ko, H.S.2    Kang, H.3
  • 94
    • 33845398283 scopus 로고    scopus 로고
    • Transcriptional regulation by insulin: From the receptor to the gene
    • Mounier C, Posner BI. Transcriptional regulation by insulin: from the receptor to the gene. Can J Physiol Pharmacol 2006; 84: 713-24.
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 713-724
    • Mounier, C.1    Posner, B.I.2
  • 95
    • 0037099766 scopus 로고    scopus 로고
    • Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson's disease
    • Lin JJ, Yueh KC, Chang DC, Lin SZ. Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson's disease. J Neurol Sci 2002; 199: 25-9.
    • (2002) J Neurol Sci , vol.199 , pp. 25-29
    • Lin, J.J.1    Yueh, K.C.2    Chang, D.C.3    Lin, S.Z.4
  • 96
    • 79960675107 scopus 로고    scopus 로고
    • Brain renin-angiotensin-A new look at an old system
    • Wright JW, Harding JW. Brain renin-angiotensin-A new look at an old system. Prog Neurobiol 2011; 95: 49-67.
    • (2011) Prog Neurobiol , vol.95 , pp. 49-67
    • Wright, J.W.1    Harding, J.W.2
  • 97
    • 62649089147 scopus 로고    scopus 로고
    • The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: Relevance to progression of the disease
    • Joglar B, Rodriguez-Pallares J, Rodriguez-Perez AI, et al. The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: relevance to progression of the disease. J Neurochem 2009; 109: 656-69.
    • (2009) J Neurochem , vol.109 , pp. 656-669
    • Joglar, B.1    Rodriguez-Pallares, J.2    Rodriguez-Perez, A.I.3
  • 98
    • 27444435057 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition reduces oxidative stress and protects dopaminergic neurons in a 6-hydroxydopamine rat model of Parkinsonism
    • Lopez-Real A, Rey P, Soto-Otero R, Mendez-Alvarez E, Labandeira-Garcia JL. Angiotensin-converting enzyme inhibition reduces oxidative stress and protects dopaminergic neurons in a 6-hydroxydopamine rat model of Parkinsonism. J Neurosci Res 2005; 81: 865-73.
    • (2005) J Neurosci Res , vol.81 , pp. 865-873
    • Lopez-Real, A.1    Rey, P.2    Soto-Otero, R.3    Mendez-Alvarez, E.4    Labandeira-Garcia, J.L.5
  • 99
    • 33745192816 scopus 로고    scopus 로고
    • Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism
    • Muñoz A, Rey P, Guerra MJ, et al. Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism. Neuropharmacology 2006; 51: 112-20.
    • (2006) Neuropharmacology , vol.51 , pp. 112-120
    • Muñoz, A.1    Rey, P.2    Guerra, M.J.3
  • 101
    • 0042027955 scopus 로고    scopus 로고
    • Angiotensin II-type 1 receptor interaction upregulates vascular endothelial growth factor messenger RNA levels in retinal pericytes through intracellular reactive oxygen species generation
    • Yamagishi S, Amano S, Inagaki Y, et al. Angiotensin II-type 1 receptor interaction upregulates vascular endothelial growth factor messenger RNA levels in retinal pericytes through intracellular reactive oxygen species generation. Drugs Exp Clin Res 2003; 29: 75-80.
    • (2003) Drugs Exp Clin Res , vol.29 , pp. 75-80
    • Yamagishi, S.1    Amano, S.2    Inagaki, Y.3
  • 102
    • 44449162751 scopus 로고    scopus 로고
    • Oxidative stress in vascular disease: Causes, defense mechanisms and potential therapies
    • Forstermann U. Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies. Nat Clin Pract Cardiovasc Med 2008; 5: 338-49.
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 338-349
    • Forstermann, U.1
  • 103
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's Disease: Mechanisms and Models
    • Dauer W, Przedborski S. Parkinson's Disease: Mechanisms and Models. Neuron 2003; 39: 889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 104
    • 18844394828 scopus 로고    scopus 로고
    • Pathogenesis of nigral cell death in Parkinson's disease
    • Przedborski S. Pathogenesis of nigral cell death in Parkinson's disease. Parkinsonism Relat Disord 2005; 11 Suppl 1: S3-7.
    • (2005) Parkinsonism Relat Disord , vol.11 , Issue.SUPPL. 1
    • Przedborski, S.1
  • 105
    • 51649110738 scopus 로고    scopus 로고
    • PPAR: A therapeutic target in Parkinsons disease
    • Chaturvedi RK, Beal MF. PPAR: a therapeutic target in Parkinsons disease. J Neurochem 2008; 106: 506-18.
    • (2008) J Neurochem , vol.106 , pp. 506-518
    • Chaturvedi, R.K.1    Beal, M.F.2
  • 106
    • 33646524699 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptors and inflammation
    • Moraes LA, Piqueras L, Bishop-Bailey D. Peroxisome proliferatoractivated receptors and inflammation. Pharmacol Therap 2006; 110: 371-85.
    • (2006) Pharmacol Therap , vol.110 , pp. 371-385
    • Moraes, L.A.1    Piqueras, L.2    Bishop-Bailey, D.3
  • 107
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-c agonist pioglitazone in a mouse model of Parkinson's disease
    • Breidert T, Callebert J, Heneka MT, et al. Protective action of the peroxisome proliferator-activated receptor-c agonist pioglitazone in a mouse model of Parkinson's disease. J Neurochem 2002; 82: 615-24.
    • (2002) J Neurochem , vol.82 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3
  • 108
    • 84858680497 scopus 로고    scopus 로고
    • Upcoming treatments in Parkinson's disease, including gene therapy
    • Rodnitzky RL. Upcoming treatments in Parkinson's disease, including gene therapy. Parkinsonism Relat Disord 2012; 18: S37-40.
    • (2012) Parkinsonism Relat Disord , vol.18
    • Rodnitzky, R.L.1
  • 109
    • 77958072667 scopus 로고    scopus 로고
    • PGC-1, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
    • Zheng B, Liao Z, Locascio JJ, et al. PGC-1, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease. Sci Transl Med 2010; 2: 52ra73.
    • (2010) Sci Transl Med , vol.2
    • Zheng, B.1    Liao, Z.2    Locascio, J.J.3
  • 110
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation
    • Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation. J Neurochem 2003; 88: 494-501.
    • (2003) J Neurochem , vol.88 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 111
    • 42949100802 scopus 로고    scopus 로고
    • The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B
    • Quinn LP, Crook B, Hows ME, et al. The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B. Br J Pharmacol 2008; 154: 226-33.
    • (2008) Br J Pharmacol , vol.154 , pp. 226-233
    • Quinn, L.P.1    Crook, B.2    Hows, M.E.3
  • 112
    • 78149407073 scopus 로고    scopus 로고
    • Acute but not chronic administration of pioglitazone promoted behavioral and neurochemical protective effects in the MPTP model of Parkinson's disease
    • Barbiero JK, Santiago RM, Lima MM, et al. Acute but not chronic administration of pioglitazone promoted behavioral and neurochemical protective effects in the MPTP model of Parkinson's disease. Behav Brain Res 2010; 216: 186-92.
    • (2010) Behav Brain Res , vol.216 , pp. 186-192
    • Barbiero, J.K.1    Santiago, R.M.2    Lima, M.M.3
  • 113
    • 0028111923 scopus 로고
    • Regulation of glucose transport by pioglitazone in cultured muscle cells
    • el-Kebbi IM, Roser S, Pollet RJ. Regulation of glucose transport by pioglitazone in cultured muscle cells. Metabolism 1994; 43: 953-8.
    • (1994) Metabolism , vol.43 , pp. 953-958
    • El-Kebbi, I.M.1    Roser, S.2    Pollet, R.J.3
  • 114
    • 0034804726 scopus 로고    scopus 로고
    • Pioglitazone: Mechanism of action
    • Smith U. Pioglitazone: mechanism of action. Int J Clin Pract Suppl 2001; 121: 13-8.
    • (2001) Int J Clin Pract Suppl , vol.121 , pp. 13-18
    • Smith, U.1
  • 115
    • 0021348288 scopus 로고
    • Acute administration of 1-N-methyl-4-phenyl-1:2:3:6-tetrahydropyridine (MPTP), a compound producing parkinsonism in humans, stimulates [2-14C]deoxyglucose uptake in the regions of the catecholaminergic cell bodies in the rat and guinea pig brains
    • Palacios JM, Wiederhold KH. Acute administration of 1-N-methyl-4-phenyl-1:2:3:6-tetrahydropyridine (MPTP), a compound producing parkinsonism in humans, stimulates [2-14C]deoxyglucose uptake in the regions of the catecholaminergic cell bodies in the rat and guinea pig brains. Brain Res 1984; 301: 187-91.
    • (1984) Brain Res , vol.301 , pp. 187-191
    • Palacios, J.M.1    Wiederhold, K.H.2
  • 116
    • 0023820072 scopus 로고
    • Administration of MPTP acutely increases glucose utilization in the substantia nigra of primates
    • Palombo E, Porrino LJ, Bankiewicz KS, Crane AM, Kopin IJ, Sokoloff L. Administration of MPTP acutely increases glucose utilization in the substantia nigra of primates. Brain Res 1988; 453: 227-34.
    • (1988) Brain Res , vol.453 , pp. 227-234
    • Palombo, E.1    Porrino, L.J.2    Bankiewicz, K.S.3    Crane, A.M.4    Kopin, I.J.5    Sokoloff, L.6
  • 117
    • 0027737466 scopus 로고
    • Sites and mechanisms of function-related changes in energy metabolism in the nervous system
    • Sokoloff L. Sites and mechanisms of function-related changes in energy metabolism in the nervous system. Dev Neurosci 1993; 15: 194-206.
    • (1993) Dev Neurosci , vol.15 , pp. 194-206
    • Sokoloff, L.1
  • 118
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
    • Breidert T, Callebert J, Heneka MT, et al. Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. J Neurochem 2002; 82: 615-24.
    • (2002) J Neurochem , vol.82 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3
  • 119
    • 77957596565 scopus 로고    scopus 로고
    • Intranigral LPS administration produces dopamine, glutathione but not behavioral impairment in comparison to MPTP and 6-OHDA neurotoxin models of Parkinson's disease
    • Ariza D, Lima MM, Moreira CG, et al. Intranigral LPS administration produces dopamine, glutathione but not behavioral impairment in comparison to MPTP and 6-OHDA neurotoxin models of Parkinson's disease. Neurochem Res 2010; 35: 1620-7.
    • (2010) Neurochem Res , vol.35 , pp. 1620-1627
    • Ariza, D.1    Lima, M.M.2    Moreira, C.G.3
  • 120
    • 33745835107 scopus 로고    scopus 로고
    • Different parkinsonism models produce a time-dependent induction of COX-2 in the substantia nigra of rats
    • Lima MMS, Braga RA, Marques ZS, et al. Different parkinsonism models produce a time-dependent induction of COX-2 in the substantia nigra of rats. Brain Res 2006; 1101: 117-25.
    • (2006) Brain Res , vol.1101 , pp. 117-125
    • Lima, M.M.S.1    Braga, R.A.2    Marques, Z.S.3
  • 121
    • 39149116014 scopus 로고    scopus 로고
    • Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague-Dawley rats
    • Hunter RL, Choi DY, Ross SA, Bing G. Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague-Dawley rats. Neurosci Lett 2008; 432: 198-201.
    • (2008) Neurosci Lett , vol.432 , pp. 198-201
    • Hunter, R.L.1    Choi, D.Y.2    Ross, S.A.3    Bing, G.4
  • 122
    • 33847005101 scopus 로고    scopus 로고
    • Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system
    • Hunter RL, Dragicevic N, Seifert K, et al. Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system. J Neurochem 2007; 100: 1375-86.
    • (2007) J Neurochem , vol.100 , pp. 1375-1386
    • Hunter, R.L.1    Dragicevic, N.2    Seifert, K.3
  • 123
    • 36749097843 scopus 로고    scopus 로고
    • Neuroprotection with pioglitazone against LPS insult on dopaminergic neurons may be associated with its inhibition of NF-κB and JNK activation and suppression of COX-2 activity
    • Xing B, Liu M, Bing G. Neuroprotection with pioglitazone against LPS insult on dopaminergic neurons may be associated with its inhibition of NF-κB and JNK activation and suppression of COX-2 activity. J Neuroimmunol 2007; 192: 89-98.
    • (2007) J Neuroimmunol , vol.192 , pp. 89-98
    • Xing, B.1    Liu, M.2    Bing, G.3
  • 124
    • 80051514413 scopus 로고    scopus 로고
    • Rosiglitazone protects neuroblastoma cells against advanced glycation end products-induced injury
    • Wang L, Yu CJ, Liu W, Cheng LY, Zhang YN. Rosiglitazone protects neuroblastoma cells against advanced glycation end products-induced injury. Acta Pharmacol Sin 2011; 32: 991-8.
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 991-998
    • Wang, L.1    Yu, C.J.2    Liu, W.3    Cheng, L.Y.4    Zhang, Y.N.5
  • 125
    • 29244476043 scopus 로고    scopus 로고
    • Rosiglitazone protects human neuroblastoma SH-SY5Y cells against acetaldehyde-induced cytotoxicity
    • Jung TW, Lee JY, Shim WS, et al. Rosiglitazone protects human neuroblastoma SH-SY5Y cells against acetaldehyde-induced cytotoxicity. Biochem Biophys Res Commun 2006; 340: 221-7.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 221-227
    • Jung, T.W.1    Lee, J.Y.2    Shim, W.S.3
  • 126
    • 33846610917 scopus 로고    scopus 로고
    • Rosiglitazone protects human neuroblastoma SH-SY5Y cells against MPP+ induced cytotoxicity via inhibition of mitochondrial dysfunction and ROS production
    • Jung TW, Lee JY, Shim WS, et al. Rosiglitazone protects human neuroblastoma SH-SY5Y cells against MPP+ induced cytotoxicity via inhibition of mitochondrial dysfunction and ROS production. J Neurol Sci 2007; 253: 53-60.
    • (2007) J Neurol Sci , vol.253 , pp. 53-60
    • Jung, T.W.1    Lee, J.Y.2    Shim, W.S.3
  • 127
    • 0038153961 scopus 로고    scopus 로고
    • Neuroprotective effects of PPARγ agonists against oxidative insults in HT-22 cells
    • Aoun P, Watson DG, Simpkins JW. Neuroprotective effects of PPARγ agonists against oxidative insults in HT-22 cells. Eur J Pharmacol 2003; 472: 65-71.
    • (2003) Eur J Pharmacol , vol.472 , pp. 65-71
    • Aoun, P.1    Watson, D.G.2    Simpkins, J.W.3
  • 129
    • 0027970799 scopus 로고
    • ATP sensitive potassium channels: Potential drug targets in neuropsychopharmacology
    • Gehlert DR, Robertson DW. ATP sensitive potassium channels: potential drug targets in neuropsychopharmacology. Prog Neuropsychopharmacol Biol Psychiatry 1994; 18(7): 1093-102.
    • (1994) Prog Neuropsychopharmacol Biol Psychiatry , vol.18 , Issue.7 , pp. 1093-1102
    • Gehlert, D.R.1    Robertson, D.W.2
  • 130
    • 18044366947 scopus 로고    scopus 로고
    • Studies of ATP-sensitive potassium channels on 6-hydroxydopamine and haloperidol rat models of Parkinson's disease: Implications for treating Parkinson's disease?
    • Wang S, Hu LF, Yang Y, Ding JH, Hu G. Studies of ATP-sensitive potassium channels on 6-hydroxydopamine and haloperidol rat models of Parkinson's disease: Implications for treating Parkinson's disease? Neuropharmacology 2005; 48: 984-92.
    • (2005) Neuropharmacology , vol.48 , pp. 984-992
    • Wang, S.1    Hu, L.F.2    Yang, Y.3    Ding, J.H.4    Hu, G.5
  • 131
    • 79959233784 scopus 로고    scopus 로고
    • Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy?
    • Carta AR, Pisanu A, Carboni E. Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy? Parkinsons Dis 2011; 2011: 1-14.
    • (2011) Parkinsons Dis , vol.2011 , pp. 1-14
    • Carta, A.R.1    Pisanu, A.2    Carboni, E.3
  • 132
    • 33747164173 scopus 로고    scopus 로고
    • Potentiating effect of the ATPsensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo
    • Kou J, Klorig DC, Bloomquist JR. Potentiating effect of the ATPsensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo. Neurotoxicology 2006; 27: 826-34.
    • (2006) Neurotoxicology , vol.27 , pp. 826-834
    • Kou, J.1    Klorig, D.C.2    Bloomquist, J.R.3
  • 133
    • 0037102937 scopus 로고    scopus 로고
    • Activation of adenosine triphosphatesensitive potassium channels confers protection against rotenoneinduced cell death: Therapeutic implications for Parkinson's disease
    • Tai KK, Truong DD. Activation of adenosine triphosphatesensitive potassium channels confers protection against rotenoneinduced cell death: Therapeutic implications for Parkinson's disease. J Neurosci Res 2002; 69: 559-66.
    • (2002) J Neurosci Res , vol.69 , pp. 559-566
    • Tai, K.K.1    Truong, D.D.2
  • 135
    • 0036299982 scopus 로고    scopus 로고
    • Metformin Increases AMPActivated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes
    • Musi N, Hirshman MF, Nygren J, et al. Metformin Increases AMPActivated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes. Diabetes 2002; 51: 2074-81.
    • (2002) Diabetes , vol.51 , pp. 2074-2081
    • Musi, N.1    Hirshman, M.F.2    Nygren, J.3
  • 136
    • 72949122084 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1:2:3:6-tetrahydropyridine
    • Choi JS, Park C, Jeong JW. AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1:2:3:6-tetrahydropyridine. Biochem Biophys Res Commun 2010; 391: 147-51.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 147-151
    • Choi, J.S.1    Park, C.2    Jeong, J.W.3
  • 137
    • 79958700336 scopus 로고    scopus 로고
    • Clarifying the role of incretin-based therapies in the treatment of type 2 diabetes mellitus
    • Campbell RK. Clarifying the role of incretin-based therapies in the treatment of type 2 diabetes mellitus. Clin Therap 2011; 33: 511-27.
    • (2011) Clin Therap , vol.33 , pp. 511-527
    • Campbell, R.K.1
  • 138
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006; 368(9548): 1696-705.
    • (2006) Lancet , vol.368 , Issue.9548 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 139
    • 84870839791 scopus 로고    scopus 로고
    • Specific actions of GLP-1 receptor agonists and DPP4 inhibitors for the treatment of pancreatic β-cell impairments in type 2 diabetes
    • Dalle S, Burcelin R, Gourdy P. Specific actions of GLP-1 receptor agonists and DPP4 inhibitors for the treatment of pancreatic β-cell impairments in type 2 diabetes. Cell Signal 2013; 25: 570-9.
    • (2013) Cell Signal , vol.25 , pp. 570-579
    • Dalle, S.1    Burcelin, R.2    Gourdy, P.3
  • 140
    • 59049087723 scopus 로고    scopus 로고
    • GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism
    • Li Y, Perry T, Kindy MS, et al. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proc Natl Acad Sci USA 2009; 106: 1285-90.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1285-1290
    • Li, Y.1    Perry, T.2    Kindy, M.S.3
  • 141
    • 45549108268 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease
    • Harkavyi A, Abuirmeileh A, Lever R, et al. Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease. J Neuroinflammation 2008; 5: 19.
    • (2008) J Neuroinflammation , vol.5 , pp. 19
    • Harkavyi, A.1    Abuirmeileh, A.2    Lever, R.3
  • 142
    • 38849196303 scopus 로고    scopus 로고
    • Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease
    • Bertilsson G, Patrone C, Zachrisson O, et al. Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease. J Neurosci Res 2008; 86: 326-38.
    • (2008) J Neurosci Res , vol.86 , pp. 326-338
    • Bertilsson, G.1    Patrone, C.2    Zachrisson, O.3
  • 143
    • 84874525661 scopus 로고    scopus 로고
    • DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption
    • Pipatpiboon N, Pintana H, Pratchayasakul W, Chattipakorn N, Chattipakorn SC. DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption. Eur J Neurosci 2013; 37(5): 839-49.
    • (2013) Eur J Neurosci , vol.37 , Issue.5 , pp. 839-849
    • Pipatpiboon, N.1    Pintana, H.2    Pratchayasakul, W.3    Chattipakorn, N.4    Chattipakorn, S.C.5
  • 144
    • 33745919520 scopus 로고    scopus 로고
    • Epidemiology of Parkinson's disease
    • de Lau LM, Breteler MM. Epidemiology of Parkinson's disease. Lancet Neurol 2006; 5: 525-35.
    • (2006) Lancet Neurol , vol.5 , pp. 525-535
    • de Lau, L.M.1    Breteler, M.M.2
  • 145
    • 60949104519 scopus 로고    scopus 로고
    • An update on preventive and regenerative therapies in diabetes mellitus
    • Reimann M, Bonifacio E, Solimena M, et al. An update on preventive and regenerative therapies in diabetes mellitus. Pharmacol Ther 2009; 121: 317-31.
    • (2009) Pharmacol Ther , vol.121 , pp. 317-331
    • Reimann, M.1    Bonifacio, E.2    Solimena, M.3
  • 146
    • 36249019041 scopus 로고    scopus 로고
    • Prospective study of dietary pattern and risk of Parkinson disease
    • Gao X, Chen H, Fung TT, et al. Prospective study of dietary pattern and risk of Parkinson disease. Am J Clin Nutr 2007; 86: 1486-94.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1486-1494
    • Gao, X.1    Chen, H.2    Fung, T.T.3
  • 147
    • 77049100951 scopus 로고    scopus 로고
    • Evaluation of chronic omega-3 fatty acids supplementation on behavioral and neurochemical alterations in 6-hydroxydopamine-lesion model of Parkinson's disease
    • Delattre AM, Kiss A, Szawka RE, et al. Evaluation of chronic omega-3 fatty acids supplementation on behavioral and neurochemical alterations in 6-hydroxydopamine-lesion model of Parkinson's disease. Neurosci Res 2010; 66: 256-64.
    • (2010) Neurosci Res , vol.66 , pp. 256-264
    • Delattre, A.M.1    Kiss, A.2    Szawka, R.E.3
  • 148
    • 42049096538 scopus 로고    scopus 로고
    • Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson's disease
    • Bousquet M, Saint-Pierre M, Julien C, et al. Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson's disease. FASEB J 2008; 22: 1213-25.
    • (2008) FASEB J , vol.22 , pp. 1213-1225
    • Bousquet, M.1    Saint-Pierre, M.2    Julien, C.3
  • 149
    • 84864505466 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids inhibit lipopolysaccharide-induced microglial activation and dopaminergic injury in rats
    • Ji A, Diao H, Wang X, et al. N-3 polyunsaturated fatty acids inhibit lipopolysaccharide-induced microglial activation and dopaminergic injury in rats. Neurotoxicology 2012; 33: 780-8.
    • (2012) Neurotoxicology , vol.33 , pp. 780-788
    • Ji, A.1    Diao, H.2    Wang, X.3
  • 150
    • 0033954157 scopus 로고    scopus 로고
    • Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids
    • Zimmer L, Delion-Vancassel S, Durand G, et al. Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids. J Lipid Res 2000; 41: 32-40.
    • (2000) J Lipid Res , vol.41 , pp. 32-40
    • Zimmer, L.1    Delion-Vancassel, S.2    Durand, G.3
  • 151
    • 44349106406 scopus 로고    scopus 로고
    • Reduced numbers of dopamine neurons in the substantia nigra pars compacta and ventral tegmental area of rats fed an n-3 polyunsaturated fatty acid-deficient diet: A stereological study
    • Ahmad SO, Park JH, Radel JD, Levant B. Reduced numbers of dopamine neurons in the substantia nigra pars compacta and ventral tegmental area of rats fed an n-3 polyunsaturated fatty acid-deficient diet: a stereological study. Neurosci Lett 2008; 438: 303-7.
    • (2008) Neurosci Lett , vol.438 , pp. 303-307
    • Ahmad, S.O.1    Park, J.H.2    Radel, J.D.3    Levant, B.4
  • 152
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 2004; 350: 664-71.
    • (2004) N Engl J Med , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 153
    • 23944468510 scopus 로고    scopus 로고
    • Energy intake, meal frequency, and health: A neurobiological perspective
    • Mattson MP. Energy intake, meal frequency, and health: a neurobiological perspective. Annu Rev Nutr 2005; 25: 237-60.
    • (2005) Annu Rev Nutr , vol.25 , pp. 237-260
    • Mattson, M.P.1
  • 154
    • 20444435980 scopus 로고    scopus 로고
    • Can type 2 diabetes mellitus be considered preventable?
    • Jermendy G. Can type 2 diabetes mellitus be considered preventable? Diabetes Res Clin Pract 2005; 68 Suppl 1: S73-81.
    • (2005) Diabetes Res Clin Pract , vol.68 , Issue.SUPPL. 1
    • Jermendy, G.1
  • 155
    • 0034088054 scopus 로고    scopus 로고
    • Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: Preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid
    • Guo Z, Ersoz A, Butterfield DA, Mattson MP. Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid. J Neurochem 2000; 75: 314-20.
    • (2000) J Neurochem , vol.75 , pp. 314-320
    • Guo, Z.1    Ersoz, A.2    Butterfield, D.A.3    Mattson, M.P.4
  • 156
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science 1996; 273: 59-63.
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 157
    • 0030935652 scopus 로고    scopus 로고
    • Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study
    • Pan XR, Li GW, Hu YH, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 1997; 20: 537-44.
    • (1997) Diabetes Care , vol.20 , pp. 537-544
    • Pan, X.R.1    Li, G.W.2    Hu, Y.H.3
  • 158
    • 82155166363 scopus 로고    scopus 로고
    • High-fat diet exacerbates MPTP-induced dopaminergic degeneration in mice
    • Bousquet M, St-Amour I, Vandal M, et al. High-fat diet exacerbates MPTP-induced dopaminergic degeneration in mice. Neurobiol Dis 2012; 45: 529-38.
    • (2012) Neurobiol Dis , vol.45 , pp. 529-538
    • Bousquet, M.1    St-Amour, I.2    Vandal, M.3
  • 160
    • 54049155669 scopus 로고    scopus 로고
    • Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats
    • Palsamy P, Subramanian S. Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats. Biomed Pharmacother 2008; 62: 598-605.
    • (2008) Biomed Pharmacother , vol.62 , pp. 598-605
    • Palsamy, P.1    Subramanian, S.2
  • 161
    • 79955959016 scopus 로고    scopus 로고
    • Coffee consumption and the incidence of type 2 diabetes in men and women with normal glucose tolerance: The Strong Heart Study
    • Zhang Y, Lee ET, Cowan LD, Fabsitz RR, Howard BV. Coffee consumption and the incidence of type 2 diabetes in men and women with normal glucose tolerance: the Strong Heart Study. Nutr Metab Cardiovasc Dis 2011; 21: 418-23.
    • (2011) Nutr Metab Cardiovasc Dis , vol.21 , pp. 418-423
    • Zhang, Y.1    Lee, E.T.2    Cowan, L.D.3    Fabsitz, R.R.4    Howard, B.V.5
  • 162
    • 84875241744 scopus 로고    scopus 로고
    • Soft drink, 100% fruit juice, and vegetable juice intakes and risk of diabetes mellitus
    • Eshak ES, Iso H, Mizoue T, et al. Soft drink, 100% fruit juice, and vegetable juice intakes and risk of diabetes mellitus. Clin Nutr 2012; 32(2): 300-8.
    • (2012) Clin Nutr , vol.32 , Issue.2 , pp. 300-308
    • Eshak, E.S.1    Iso, H.2    Mizoue, T.3
  • 163
    • 84858992662 scopus 로고    scopus 로고
    • Green tea catechins ameliorate adipose insulin resistance by improving oxidative stress
    • Yan J, Zhao Y, Suo S, Liu Y, Zhao B. Green tea catechins ameliorate adipose insulin resistance by improving oxidative stress. Free Radic Biol Med 2012; 52: 1648-57.
    • (2012) Free Radic Biol Med , vol.52 , pp. 1648-1657
    • Yan, J.1    Zhao, Y.2    Suo, S.3    Liu, Y.4    Zhao, B.5
  • 164
    • 51549098145 scopus 로고    scopus 로고
    • Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity
    • Chao J, Yu MS, Ho YS, Wang M, Chang RC. Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity. Free Radic Biol Med 2008; 45: 1019-26.
    • (2008) Free Radic Biol Med , vol.45 , pp. 1019-1026
    • Chao, J.1    Yu, M.S.2    Ho, Y.S.3    Wang, M.4    Chang, R.C.5
  • 165
  • 166
    • 84867896217 scopus 로고    scopus 로고
    • Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms
    • Marques-Aleixo I, Oliveira PJ, Moreira PI, Magalhaes J, Ascensao A. Physical exercise as a possible strategy for brain protection: evidence from mitochondrial-mediated mechanisms. Prog Neurobiol 2012; 99: 149-62.
    • (2012) Prog Neurobiol , vol.99 , pp. 149-162
    • Marques-Aleixo, I.1    Oliveira, P.J.2    Moreira, P.I.3    Magalhaes, J.4    Ascensao, A.5
  • 167
    • 42549104547 scopus 로고    scopus 로고
    • Physical education, school physical activity, school sports and academic performance
    • Trudeau F, Shephard RJ. Physical education, school physical activity, school sports and academic performance. Int J Behav Nutr Phys Act 2008; 5: 10.
    • (2008) Int J Behav Nutr Phys Act , vol.5 , pp. 10
    • Trudeau, F.1    Shephard, R.J.2
  • 168
    • 50649103271 scopus 로고    scopus 로고
    • Downhill training upregulates mice hippocampal and striatal brainderived neurotrophic factor levels
    • Aguiar AS Jr, Speck AE, Prediger RD, Kapczinski F, Pinho RA. Downhill training upregulates mice hippocampal and striatal brainderived neurotrophic factor levels. J Neural Transm 2008; 115: 1251-5.
    • (2008) J Neural Transm , vol.115 , pp. 1251-1255
    • Aguiar Jr., A.S.1    Speck, A.E.2    Prediger, R.D.3    Kapczinski, F.4    Pinho, R.A.5
  • 170
    • 84868520286 scopus 로고    scopus 로고
    • Physical training exerts neuroprotective effects in the regulation of neurochemical factors in an animal model of Parkinson's disease
    • Tuon T, Valvassori SS, Lopes-Borges J, et al. Physical training exerts neuroprotective effects in the regulation of neurochemical factors in an animal model of Parkinson's disease. Neuroscience 2012; 227: 305-12.
    • (2012) Neuroscience , vol.227 , pp. 305-312
    • Tuon, T.1    Valvassori, S.S.2    Lopes-Borges, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.