Activation of adenosine triphosphate-sensitive potassium channels confers protection against rotenone-induced cell death: Therapeutic implications for Parkinson's disease

Journal of Neuroscience Research

Volumn 69, Issue 4, 2002, Pages 559-566

  Tai, Kwok Keung ^a,b   Truong, Daniel D ^a  

^a LONG BEACH MEMORIAL MEDICAL CENTER   (United States)

^b Parkinson's and Movement Disorder Institute   (United States)

Author keywords

ATP sensitive potassium channels; Ischemic preconditioning; Parkinson's disease; Pheochromocytoma cells; Rotenone

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ADENOSINE TRIPHOSPHATE; FERROUS SULFATE; POTASSIUM CHANNEL; PROTEIN SYNTHESIS INHIBITOR; ROTENONE; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; BRAIN PROTECTION; CELL DEATH; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX I; FERROUS COMPOUNDS; GLYBURIDE; ISCHEMIC PRECONDITIONING; MITOCHONDRIA; NADH, NADPH OXIDOREDUCTASES; NEURONS; PARKINSON DISEASE; PARKINSON DISEASE, SECONDARY; PC12 CELLS; PINACIDIL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PROTEIN SYNTHESIS INHIBITORS; RATS; ROTENONE; UNCOUPLING AGENTS; VASODILATOR AGENTS; XANTHINE; XANTHINE OXIDASE;

EID: 0037102937     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10309     Document Type: Article

References (40)

1. 1-Methyl-4-(2′-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells is enhanced by preventing glycolysis
2. Chronic systemic pesticide exposure reproduces features of Parkinson's disease
3. K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection
4. Alzheimer's disease: A review concerning immune response and microischemia
5. ATP channels
6. Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs
7. Cellular mechanisms in ischemic preconditioning: The role of adenosine and protein kinase C
8. ATP-sensitive potassium channels (K-ATP) in retina: A key role for delayed ischemic tolerance
9. +-induced apoptosis in human SH-SY5Y neuroblastoma cells
10. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra
11. Nitric oxide mediates cerebral ischaemic tolerance in a neonatal rat model of hypoxic preconditioning
12. ras/extracellular regulated kinase in neuronal ischemic preconditioning
13. + channel openers protect hippocampal neurons against oxidant injury and amyloid beta-peptide toxicity
14. + channels by chronic glyburide and pinacidil administration
15. Complex I inhibitors induce dose-dependent apoptosis in PC 12 cells: Relevance to Parkinson's disease
16. + channels in cerebral ischemic preconditioning
17. Mechanisms of ischemic preconditioning
18. Parkinson's disease, pesticides and mitochondrial dysfunction
19. Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation
20. Ischemic tolerance phenomenon found in the brain
21. 6-Hydroxydopamine lesioning of the nigrostriatal pathway in rats alters basal ganglia mRNA for copper-, zinc and manganese-superoxidase dismutase, but not glutathione peroxidase
22. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
23. NS 1619 activates BKCa channel activity in rat cortical neurons
24. Effect of nerve growth factor on glucose utilization and nucleotide content of pheochromocytoma cells (clone PC12)
25. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
26. Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals
27. + ATP channel and protein kinase C
28. Warburg effect revisited: Merges of biochemistry and molecular biology
29. Preconditioninginduced neuroprotection is mediated by reactive oxygen species
30. Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor-kappa B
31. Opening of ATP-sensitive potassium channels by cromakalim confers tolerance against chemical ischemia in rat neuronal cultures
32. Ischemic preconditioning of the vasculature: An overlooked phenomenon for protecting the heart?
33. Ischemic preconditioning improves cardiac functional recovery following preservation with University of Wisconsin solution
34. Ischemic preconditioning: Differences in protection and susceptibility to blockade with single-cycle versus multicycle transient ischemia
35. + induced apoptotic cell death in SH-SY5Y neuroblastoma cells: An electron microscope study
36. An NMDA receptor channel blocker with neuroprotective activity
37. Evidence from cultured cortical neurons of differences in the mechanism of ischemic preconditioning of brain and heart
38. Pesticides directly accelerate the rate of alpha-synuclein fibril formation: A possible factor in Parkinson's disease
39. Activation of ATP-sensitive potassium channels decreases neuronal injury caused by chemical hypoxia