-
1
-
-
0347003669
-
Pyridine oximes: Synthesis, reactions, and biological activity
-
(Review)
-
Abele E, Abele R, Lukevics E (2003) Pyridine oximes: synthesis, reactions, and biological activity (Review). Chem Heterocycl Compd 39(7):825-865
-
(2003)
Chem Heterocycl Compd
, vol.39
, Issue.7
, pp. 825-865
-
-
Abele, E.1
Abele, R.2
Lukevics, E.3
-
2
-
-
3342904522
-
Pyrrole oximes: Synthesis, reactions, and biological activity
-
(Review)
-
Abele E, Abele R, Lukevics E (2004) Pyrrole oximes: synthesis, reactions, and biological activity (Review). Chem Heterocycl Compd 40(1):1-15
-
(2004)
Chem Heterocycl Compd
, vol.40
, Issue.1
, pp. 1-15
-
-
Abele, E.1
Abele, R.2
Lukevics, E.3
-
3
-
-
33947687574
-
Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis
-
Baumer W, Hoppmann J, Rundfeldt C, Kietzmann M (2007) Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis. Inflamm Allergy Drug Targets 6(1):17-26 (Pubitemid 46488295)
-
(2007)
Inflammation and Allergy - Drug Targets
, vol.6
, Issue.1
, pp. 17-26
-
-
Baumer, W.1
Hoppmann, J.2
Rundfeldt, C.3
Kietzmann, M.4
-
4
-
-
80054853903
-
Fused pyrazino [2, 3-b] indolizine and indolizino [2, 3-b] quinoxaline derivatives; synthesis, structures, and properties
-
Bloch WM, Derwent-Smith SM, Issa F, Morris JC, Rendina LM, Sumby CJ (2011) Fused pyrazino [2, 3-b] indolizine and indolizino [2, 3-b] quinoxaline derivatives; synthesis, structures, and properties. Tetrahedron 67(48):9368-9375
-
(2011)
Tetrahedron
, vol.67
, Issue.48
, pp. 9368-9375
-
-
Bloch, W.M.1
Derwent-Smith, S.M.2
Issa, F.3
Morris, J.C.4
Rendina, L.M.5
Sumby, C.J.6
-
5
-
-
16244413613
-
Phase II trial of oral rubitecan in previously treated pancreatic cancer patients
-
DOI 10.1634/theoncologist.10-3-183
-
Burris HA, Rivkin S, Reynolds R, Harris J, Wax A, Gerstein H, Mettinger KL, Staddon A (2005) Phase II trial of oral rubitecan in previously treated pancreatic cancer patients. Oncologist 10(3):183-190 (Pubitemid 40463155)
-
(2005)
Oncologist
, vol.10
, Issue.3
, pp. 183-190
-
-
Burris III, H.A.1
Rivkin, S.2
Reynolds, R.3
Harris, J.4
Wax, A.5
Gerstein, H.6
Mettinger, K.L.7
Staddon, A.8
-
6
-
-
11344292132
-
The role of natural product chemistry in drug discovery
-
2004
-
Butler MS (2004) The role of natural product chemistry in drug discovery. J Nat Prod 67(12):2141-2153 2004
-
(2004)
J Nat Prod
, vol.67
, Issue.12
, pp. 2141-2153
-
-
Butler, M.S.1
-
7
-
-
17844399025
-
Natural products to drugs: Natural product derived compounds in clinical trials
-
Butler MS (2005) Natural products to drugs: natural product derived compounds in clinical trials. Nat Prod Rep 22(2):162-195
-
(2005)
Nat Prod Rep
, vol.22
, Issue.2
, pp. 162-195
-
-
Butler, M.S.1
-
8
-
-
44249098800
-
Natural products to drugs: Natural product-derived compounds in clinical trials
-
Butler MS (2008) Natural products to drugs: natural product-derived compounds in clinical trials. Nat Prod Rep 25(3):475-516
-
(2008)
Nat Prod Rep
, vol.25
, Issue.3
, pp. 475-516
-
-
Butler, M.S.1
-
9
-
-
0038702085
-
3 receptor antagonists
-
DOI 10.1016/S0960-894X(03)00299-3
-
Chai W, Breitenbucher JG, Kwok A, Li X, Wong V, Carruthers NI, Lovenberg TW, Mazur C, Wilson SJ, Axe FU, Jones TK (2003) Non-imidazole heterocyclic histamine H3 receptor antagonists. Bioorg Med Chem Lett 13(10):1767-1770 (Pubitemid 36561161)
-
(2003)
Bioorganic and Medicinal Chemistry Letters
, vol.13
, Issue.10
, pp. 1767-1770
-
-
Chai, W.1
Breitenbucher, J.G.2
Kwok, A.3
Li, X.4
Wong, V.5
Carruthers, N.I.6
Lovenberg, T.W.7
Mazur, C.8
Wilson, S.J.9
Axe, F.U.10
Jones, T.K.11
-
10
-
-
44849103406
-
Synthesis and antioxidant activity of 3, 3′-diselanediylbis(N, N-disubstituted indolizine-1-carboxamide):And derivatives
-
Chandrashekhar N, Karvekar MD, Das AK (2008) Synthesis and antioxidant activity of 3, 3′-diselanediylbis(N, N-disubstituted indolizine-1- carboxamide):and derivatives. S Afr J Chem 61:53-55
-
(2008)
S Afr J Chem
, vol.61
, pp. 53-55
-
-
Chandrashekhar, N.1
Karvekar, M.D.2
Das, A.K.3
-
11
-
-
79952505997
-
Novel indolizine compounds as potent inhibitors of phosphodiesterase IV(PDE4): Structure-activity relationship
-
Chen S, Xia Z, Nagai M, Lu R, Kostik E, Przewloka T, Song M, Chimmanamada D, James D, Zhang S, Jiang J, Ono M, Koya K, Sun L (2011) Novel indolizine compounds as potent inhibitors of phosphodiesterase IV(PDE4): structure-activity relationship. MedChemComm 2(3):176-180
-
(2011)
MedChemComm
, vol.2
, Issue.3
, pp. 176-180
-
-
Chen, S.1
Xia, Z.2
Nagai, M.3
Lu, R.4
Kostik, E.5
Przewloka, T.6
Song, M.7
Chimmanamada, D.8
James, D.9
Zhang, S.10
Jiang, J.11
Ono, M.12
Koya, K.13
Sun, L.14
-
12
-
-
42149147572
-
Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: Indolizinoquinoline-5,12-dione derivatives
-
DOI 10.1016/j.bmc.2008.02.036, PII S0968089608001570
-
Cheng Y, An LK, Wu N, Wang XD, Bu XZ, Huang ZS, Gu LQ (2008) Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: indolizinoquinoline-5,12-dione derivatives. Bioorg Med Chem 16(8):4617-4625 (Pubitemid 351539023)
-
(2008)
Bioorganic and Medicinal Chemistry
, vol.16
, Issue.8
, pp. 4617-4625
-
-
Cheng, Y.1
An, L.-K.2
Wu, N.3
Wang, X.-D.4
Bu, X.-Z.5
Huang, Z.-S.6
Gu, L.-Q.7
-
13
-
-
0023755197
-
Indolizine derivatives with biological activity V 1-(2-Aminoethyl)-2- methylindolizine and its N-alkyl derivatives
-
Cingolani GM, Claudi F, Venturi F (1988) Indolizine derivatives with biological activity V 1-(2-Aminoethyl)-2-methylindolizine and its N-alkyl derivatives. Eur J Med Chem 23(3):291-294
-
(1988)
Eur J Med Chem
, vol.23
, Issue.3
, pp. 291-294
-
-
Cingolani, G.M.1
Claudi, F.2
Venturi, F.3
-
14
-
-
0025202285
-
Indolizine derivatives with biological activity VI 1-(2-aminoethyl)-3- benzyl-7-methoxy-2-methylindolizine, benanserin structural analogue
-
Cingolani GM, Claudi F, Massi M, Venturi F (1990) Indolizine derivatives with biological activity VI 1-(2-aminoethyl)-3-benzyl-7-methoxy-2- methylindolizine, benanserin structural analogue. Eur J Med Chem 25(8):709-712
-
(1990)
Eur J Med Chem
, vol.25
, Issue.8
, pp. 709-712
-
-
Cingolani, G.M.1
Claudi, F.2
Massi, M.3
Venturi, F.4
-
15
-
-
0035373635
-
Synthesis and in vitro activity of a non-epimerizable analog of the angiotensin-converting enzyme inhibitor A58365A
-
DOI 10.1016/S1387-1609(01)01263-4
-
Clive DLJ, Yang H, Lewanczuk RZ (2001) Synthesis and in vitro activity of a non-epimerizable analog of the angiotensin-converting enzyme inhibitor A58365A. CR Acad Sci Ser IIc: Chim 4(6):505-512 (Pubitemid 33376684)
-
(2001)
Comptes Rendus de l'Academie des Sciences - Series IIc: Chemistry
, vol.4
, Issue.6
, pp. 505-512
-
-
Clive, D.L.J.1
Yang, H.2
Lewanczuk, R.Z.3
-
16
-
-
0029056755
-
The use of estrogens and progestins and the risk of breast cancer in postmenopausal women
-
Colditz GA, Hankinson SE, Hunter DJ, Willett WC, Manson JE, Stampfer MJ, Hennekens C, Rosner B, Speizer FE (1995) The use of estrogens and progestins and the risk of breast cancer in postmenopausal women. N Engl J Med 332(24):1589-1593
-
(1995)
N Engl J Med
, vol.332
, Issue.24
, pp. 1589-1593
-
-
Colditz, G.A.1
Hankinson, S.E.2
Hunter, D.J.3
Willett, W.C.4
Manson, J.E.5
Stampfer, M.J.6
Hennekens, C.7
Rosner, B.8
Speizer, F.E.9
-
17
-
-
0035960061
-
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity
-
DOI 10.1021/jm0108092
-
Dallavalle S, Ferrari A, Biasotti B, Merlini L, Penco S, Gallo G, Marzi M, Tinti MO, Martinelli R, Pisano C, Carminati P, Carenini N, Beretta G, Perego P, De Cesare M, Pratesi G, Zunino F (2001) Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity. J Med Chem 44(20):3264-3274 (Pubitemid 32917106)
-
(2001)
Journal of Medicinal Chemistry
, vol.44
, Issue.20
, pp. 3264-3274
-
-
Dallavalle, S.1
Ferrari, A.2
Biasotti, B.3
Merlini, L.4
Penco, S.5
Gallo, G.6
Marzi, M.7
Tinti, M.O.8
Martinelli, R.9
Pisano, C.10
Carminati, P.11
Carenini, N.12
Beretta, G.13
Perego, P.14
De Cesare, M.15
Pratesi, G.16
Zunino, F.17
-
18
-
-
0023612659
-
Antimycobacterial 7-hydroxy-2, 3-dihydro-1H-indolizin-5-ones
-
Dannhardt G, Meindl W, Gussmann S, Ajili S, Kappe T (1987) Antimycobacterial 7-hydroxy-2, 3-dihydro-1H-indolizin-5-ones. Eur J Med Chem 22(6):505-510
-
(1987)
Eur J Med Chem
, vol.22
, Issue.6
, pp. 505-510
-
-
Dannhardt, G.1
Meindl, W.2
Gussmann, S.3
Ajili, S.4
Kappe, T.5
-
19
-
-
44449083752
-
Facile synthesis of heterocycles via 2-picolinium bromide and antimicrobial activities of the products
-
Darwish ES (2008) Facile synthesis of heterocycles via 2-picolinium bromide and antimicrobial activities of the products. Molecules 13(5):1066-1078
-
(2008)
Molecules
, vol.13
, Issue.5
, pp. 1066-1078
-
-
Darwish, E.S.1
-
20
-
-
0035476245
-
Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin
-
De Cesare M, Pratesi G, Perego P, Carenini N, Tinelli S, Merlini L, Penco S, Pisano C, Bucci F, Vesci L, Pace S, Capocasa F, Carminati P, Zunino F (2001) Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin. Cancer Res 61(19):7189-7195 (Pubitemid 32946514)
-
(2001)
Cancer Research
, vol.61
, Issue.19
, pp. 7189-7195
-
-
De Cesare, M.1
Pratesi, G.2
Perego, P.3
Carenini, N.4
Tinelli, S.5
Merlini, L.6
Penco, S.7
Pisano, C.8
Bucci, F.9
Vesci, L.10
Pace, S.11
Capocasa, F.12
Carminati, P.13
Zunino, F.14
-
21
-
-
3142686746
-
BN80927: A novel homocamptothechin that inhibits proliferation of human tumor cells in vitro and in vivo
-
DOI 10.1158/0008-5472.CAN-03-3872
-
Demarquay D, Huchet M, Coulomb H, Lesueur-Ginot L, Lavergne O, Camara J, Kasprzyk PG, Prevost G, Bigg DC (2004) BN80927: a novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo. Cancer Res 64(14):4942-4949 (Pubitemid 38924541)
-
(2004)
Cancer Research
, vol.64
, Issue.14
, pp. 4942-4949
-
-
Demarquay, D.1
Huchet, M.2
Coulomb, H.3
Lesueur-Ginot, L.4
Lavergne, O.5
Camara, J.6
Kasprzyk, P.G.7
Prevost, G.8
Bigg, D.C.H.9
-
23
-
-
0033964846
-
Phosphatases and kinases delivered to the host cell by bacterial pathogens
-
DOI 10.1016/S0966-842X(99)01657-1, PII S0966842X99016571
-
DeVinney R, Steele-Mortimer O, Finlay BB (2000) Phosphatases and kinases delivered to the host cell by bacterial pathogens. Trends Microbiol 8(1):29-33 (Pubitemid 30066381)
-
(2000)
Trends in Microbiology
, vol.8
, Issue.1
, pp. 29-33
-
-
DeVinney, R.1
Steele-Mortimer, O.2
Finlay, B.B.3
-
24
-
-
0038451558
-
Antimycobacterial activity of 1-substituted indolizines
-
DOI 10.1002/ardp.200390019
-
Gundersen LL, Negussie AH, Rise F, Ostby OB (2003) Antimycobacterial activity of 1-substituted indolizines. Arch Pharm Pharm Med Chem 336(3):191-195 (Pubitemid 36790988)
-
(2003)
Archiv der Pharmazie
, vol.336
, Issue.3
, pp. 191-195
-
-
Gundersen, L.-L.1
Negussie, A.H.2
Rise, F.3
Ostby, O.B.4
-
25
-
-
79960575547
-
Synthesis of 9-(heteroarylmethylidene) amino derivatives of homocamptothecin with biological activities
-
Guo W, Miao Z, Sheng C, Yao J, Liu W, Zhu L, Zhang Y, Cheng P, Dong G, Zhuang C, Zhang W (2011) Synthesis of 9-(heteroarylmethylidene) amino derivatives of homocamptothecin with biological activities. Chem Biodivers 8(7):1266-1273
-
(2011)
Chem Biodivers
, vol.8
, Issue.7
, pp. 1266-1273
-
-
Guo, W.1
Miao, Z.2
Sheng, C.3
Yao, J.4
Liu, W.5
Zhu, L.6
Zhang, Y.7
Cheng, P.8
Dong, G.9
Zhuang, C.10
Zhang, W.11
-
26
-
-
9544235161
-
Potent inhibitors of secretory phospholipase A2: Synthesis and inhibitory activities of indolizine and indene derivatives
-
DOI 10.1021/jm960395q
-
Hagishita S, Yamada M, Shirahase K, Okada T, Murakami Y, Ito Y, Matsuura T, Wada M, Kato T, Ueno M, Chikazawa Y, Yamada K, Ono T, Teshirogi I, Ohtani M (1996) Potent inhibitors of secretory phospholipase A2: synthesis and inhibitory activities of indolizine and indene derivatives. J Med Chem 39(19):3636-3658 (Pubitemid 26307871)
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.19
, pp. 3636-3658
-
-
Hagishita, S.1
Yamada, M.2
Shirahase, K.3
Okada, T.4
Murakami, Y.5
Ito, Y.6
Matsuura, T.7
Wada, M.8
Kato, T.9
Ueno, M.10
Chikazawa, Y.11
Yamada, K.12
Ono, T.13
Teshirogi, I.14
Ohtani, M.15
-
27
-
-
0014053978
-
Mannich bases from 2-phenylindolizines I 3-Alkyl-1-dialkylaminomethyl derivatives
-
Harrell WB, Doerge RF (1967) Mannich bases from 2-phenylindolizines I 3-Alkyl-1-dialkylaminomethyl derivatives. J Pharm Sci 56(2):225-228
-
(1967)
J Pharm Sci
, vol.56
, Issue.2
, pp. 225-228
-
-
Harrell, W.B.1
Doerge, R.F.2
-
28
-
-
79955597284
-
Amberlite-IRA-402(OH):Ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products
-
Hazra A, Mondal S, Maity A, Naskar S, Saha P, Paira R, Sahu KB, Paira P, Ghosh S, Sinha C, Samanta A, Banerjee S, Mondal NB (2011) Amberlite-IRA-402(OH): ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. Eur J Med Chem 46(6):2132-2140
-
(2011)
Eur J Med Chem
, vol.46
, Issue.6
, pp. 2132-2140
-
-
Hazra, A.1
Mondal, S.2
Maity, A.3
Naskar, S.4
Saha, P.5
Paira, R.6
Sahu, K.B.7
Paira, P.8
Ghosh, S.9
Sinha, C.10
Samanta, A.11
Banerjee, S.12
Mondal, N.B.13
-
29
-
-
0001157320
-
Castanospermine, A 1,6,7,8-tetrahydroxyoctahydroindolizine alkaloid, from seeds of Castanospermum australe
-
Hohenschutz LD, Bell EA, Jewess PJ, Leworthy DP, Pryce RJ, Arnold E, Clardy J (1981) Castanospermine, A 1,6,7,8-tetrahydroxyoctahydroindolizine alkaloid, from seeds of Castanospermum australe. Phytochemistry 20(4):811-814
-
(1981)
Phytochemistry
, vol.20
, Issue.4
, pp. 811-814
-
-
Hohenschutz, L.D.1
Bell, E.A.2
Jewess, P.J.3
Leworthy, D.P.4
Pryce, R.J.5
Arnold, E.6
Clardy, J.7
-
30
-
-
0242329757
-
Microvascular mechanisms by which the combretastatin A-4 derivative AC7700 (AVE8062) induces tumour blood flow stasis
-
DOI 10.1038/sj.bjc.6601261
-
Hori K, Saito S (2003) Microvascular mechanisms by which the combretastatin A-4 derivative AC7700(AVE8062):induces tumour blood flow stasis. Br J Cancer 89(7):1334-1344 (Pubitemid 37363426)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.7
, pp. 1334-1344
-
-
Hori, K.1
Saito, S.2
-
31
-
-
27344449614
-
Keynote review: Phosphodiesterase-4 as a therapeutic target
-
DOI 10.1016/S1359-6446(05)03622-6, PII S1359644605036226
-
Houslay MD, Schafer P, Zhang KY (2005) Keynote review: phosphodiesterase-4 as a therapeutic target. Drug Discov Today 10(22):1503-1519 (Pubitemid 41527193)
-
(2005)
Drug Discovery Today
, vol.10
, Issue.22
, pp. 1503-1519
-
-
Houslay, M.D.1
Schafer, P.2
Zhang, K.Y.J.3
-
32
-
-
33750539959
-
Phosphodiesterase 4 inhibitors for the treatment of asthma and COPD
-
DOI 10.2174/092986706778773040
-
Huang Z, Mancini JA (2006) Phosphodiesterase 4 inhibitors for the treatment of asthma and COPD. Curr Med Chem 13(27):3253-3562 (Pubitemid 44669773)
-
(2006)
Current Medicinal Chemistry
, vol.13
, Issue.27
, pp. 3253-3562
-
-
Huang, Z.1
Mancini, J.A.2
-
33
-
-
0023942587
-
Structure elucidation of A58365A and A58365B, angiotensin converting enzyme inhibitors produced by Streptomyces chromofuscus
-
Hunt AH, Mynderse JS, Samlaska SK, Fukuda DS, Maciak GM, Kirst HA, Occolowitz JL, Swartzendruber JK, Jones ND (1988) Structure elucidation of A58365A and A58365B, angiotensin converting enzyme inhibitors produced by Streptomyces chromofuscus. J Antibiot 41(6):771-779
-
(1988)
J Antibiot
, vol.41
, Issue.6
, pp. 771-779
-
-
Hunt, A.H.1
Mynderse, J.S.2
Samlaska, S.K.3
Fukuda, D.S.4
Maciak, G.M.5
Kirst, H.A.6
Occolowitz, J.L.7
Swartzendruber, J.K.8
Jones, N.D.9
-
34
-
-
84904440997
-
An innovation driven International Specialty Pharma
-
pdf. Accessed 23 Jan 2014
-
Ipsen (2008) An innovation driven International Specialty Pharma http://www.ipsen.com/wpcontent/uploads/2013/02/20080318. Lehman brothers 10th annual global healthcare conference Miami 11.pdf. Accessed 23 Jan 2014
-
(2008)
Lehman Brothers 10th Annual Global Healthcare Conference Miami 11
-
-
-
36
-
-
3042699598
-
Synthesis of antileishmanial(5R)-(-)-5-carbomethoxy-3-for-myl-5, 6-dihydroindolo-[2, 3-a]-indolizine
-
Jaisankar P, Pal B, Manna RK, Pradhan PK, Medda S, Basu MK, Giri VS (2003) Synthesis of antileishmanial(5R)-(-)-5-carbomethoxy-3-for-myl-5, 6-dihydroindolo-[2, 3-a]-indolizine. ARKIVOC ix:150-157
-
(2003)
ARKIVOC
, vol.9
, pp. 150-157
-
-
Jaisankar, P.1
Pal, B.2
Manna, R.K.3
Pradhan, P.K.4
Medda, S.5
Basu, M.K.6
Giri, V.S.7
-
37
-
-
40749158239
-
Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines
-
DOI 10.1016/j.bmcl.2008.02.029, PII S0960894X08002126
-
James DA, Koya K, Li H, Liang G, Xia Z, Ying W, Wu Y, Sun L (2008) Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines. Bioorg Med Chem Lett 18(6):1784-1787 (Pubitemid 351380911)
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.6
, pp. 1784-1787
-
-
James, D.A.1
Koya, K.2
Li, H.3
Liang, G.4
Xia, Z.5
Ying, W.6
Wu, Y.7
Sun, L.8
-
38
-
-
0026560512
-
In vitro and in vivo enhancement of ricin-A chain immunotoxin activity by novel indolizine calcium channel blockers: Delayed intracellular degradation linked to lipidosis induction
-
Jean-Pierre J, Levade T, Thurneyssen O, Chiron M, Bordier C, Michel Attal, Pierre Chatelain, Laurent G (1992) In vitro and in vivo enhancement of ricin-A chain immunotoxin activity by novel indolizine calcium channel blockers: delayed intracellular degradation linked to lipidosis induction. Cancer Res 52(5):1352-1359
-
(1992)
Cancer Res
, vol.52
, Issue.5
, pp. 1352-1359
-
-
Jean-Pierre, J.1
Levade, T.2
Thurneyssen, O.3
Chiron, M.4
Bordier, C.5
Attal, M.6
Chatelain, P.7
Laurent, G.8
-
39
-
-
0034696378
-
Synthesis and pharmacology of a novel pyrrolo[2,1,5-cd] indolizine (NNC 45-0095), a high affinity non-steroidal agonist for the estrogen receptor
-
DOI 10.1016/S0960-894X(00)00015-9, PII S0960894X00000159
-
Jorgensen AS, Jacobsen P, Christiansen LB, Bury PS, Kanstrup A, Thorpe SM, Bain S, Naerum L, Wassermann K (2000a) Synthesis and pharmacology of a novel pyrrolo[2,1,5-cd] indolizine(NNC 45-0095), a high affinity non-steroidal agonist for the estrogen receptor. Bioorg Med Chem Lett 10(4):399-402 (Pubitemid 30127869)
-
(2000)
Bioorganic and Medicinal Chemistry Letters
, vol.10
, Issue.4
, pp. 399-402
-
-
Jorgensen, A.S.1
Jacobsen, P.2
Christiansen, L.B.3
Bury, P.S.4
Kanstrup, A.5
Thorpe, S.M.6
Bain, S.7
Naerum, L.8
Wassermann, K.9
-
40
-
-
0034675705
-
Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives
-
Jorgensen AS, Jacobsen P, Christiansen LB, Bury PS, Kanstrup A, Thorpe SM, Naerum L, Wassermann K (2000b) Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives. Bioorg Med Chem Lett 10(20): 2383-2386
-
(2000)
Bioorg Med Chem Lett
, vol.10
, Issue.20
, pp. 2383-2386
-
-
Jorgensen, A.S.1
Jacobsen, P.2
Christiansen, L.B.3
Bury, P.S.4
Kanstrup, A.5
Thorpe, S.M.6
Naerum, L.7
Wassermann, K.8
-
41
-
-
84872820836
-
A valuable insight into recent advances on antimicrobial activity of piperazine derivatives
-
Kharb R, Bansal K, Sharma AK (2012) A valuable insight into recent advances on antimicrobial activity of piperazine derivatives. Der Pharma Chemica 4(6):2470-2488
-
(2012)
Der Pharma Chemica
, vol.4
, Issue.6
, pp. 2470-2488
-
-
Kharb, R.1
Bansal, K.2
Sharma, A.K.3
-
42
-
-
77956649106
-
Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents
-
Kim ND, Park ES, Kim YH, Moon SK, Lee SS, Ahn SK, Yu DY, No KT, Kim KH (2010) Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents. Bioorg Med Chem 18(19):7092-7100
-
(2010)
Bioorg Med Chem
, vol.18
, Issue.19
, pp. 7092-7100
-
-
Kim, N.D.1
Park, E.S.2
Kim, Y.H.3
Moon, S.K.4
Lee, S.S.5
Ahn, S.K.6
Yu, D.Y.7
No, K.T.8
Kim, K.H.9
-
43
-
-
84863344528
-
Efficacy and toxicity of Belotecan for relapsed or refractory small cell lung cancer patients
-
Kim GM, Kim YS, Kang YA, Jeong J-H, Kim SM, Hong YK, Sung JH, Lim ST, Kim JH, Kim SK, Cho BC (2012) Efficacy and toxicity of Belotecan for relapsed or refractory small cell lung cancer patients. J Thorac Oncol 7(4):731-736
-
(2012)
J Thorac Oncol
, vol.7
, Issue.4
, pp. 731-736
-
-
Kim, G.M.1
Kim, Y.S.2
Kang, Y.A.3
Jeong, J.-H.4
Kim, S.M.5
Hong, Y.K.6
Sung, J.H.7
Lim, S.T.8
Kim, J.H.9
Kim, S.K.10
Cho, B.C.11
-
44
-
-
0033806882
-
Cloning and characterization of secretory tyrosine phosphatases of Mycobacterium tuberculosis
-
Koul A, Choidas A, Treder M, Tyagi AK, Drlica K, Singh Y, Ullrich A (2000) Cloning and characterization of secretory tyrosine phosphatases of Mycobacterium tuberculosis. J Bacteriol 182(19):5425-5432
-
(2000)
J Bacteriol
, vol.182
, Issue.19
, pp. 5425-5432
-
-
Koul, A.1
Choidas, A.2
Treder, M.3
Tyagi, A.K.4
Drlica, K.5
Singh, Y.6
Ullrich, A.7
-
45
-
-
77949908330
-
Biological activities of quinoline derivatives Mini-Rev
-
Kumar S, Bawa S, Gupta H (2009) Biological activities of quinoline derivatives Mini-Rev. Med Chem 9(14):1648-1654
-
(2009)
Med Chem
, vol.9
, Issue.14
, pp. 1648-1654
-
-
Kumar, S.1
Bawa, S.2
Gupta, H.3
-
46
-
-
79955709914
-
Imidazole and its biological activities: A review
-
Kumari S, Sharma PK, Kumar N (2010) Imidazole and its biological activities: a review. Chem Sin 1:36-47
-
(2010)
Chem Sin
, vol.1
, pp. 36-47
-
-
Kumari, S.1
Sharma, P.K.2
Kumar, N.3
-
47
-
-
17044389329
-
Pyrimidine as constituent of natural biologically active compounds
-
Lagoja IM (2005) Pyrimidine as constituent of natural biologically active compounds. Chem Biodivers 2(1):1-50
-
(2005)
Chem Biodivers
, vol.2
, Issue.1
, pp. 1-50
-
-
Lagoja, I.M.1
-
48
-
-
0028234548
-
The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression
-
Lee WS, Kanai Y, Wells RG, Hediger MA (1994) The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression. J Biol Chem 269(16):12032-12039
-
(1994)
J Biol Chem
, vol.269
, Issue.16
, pp. 12032-12039
-
-
Lee, W.S.1
Kanai, Y.2
Wells, R.G.3
Hediger, M.A.4
-
49
-
-
0003954543
-
-
Elsevier, Amsterdam
-
Leurs R, Blandina P, Tedford C, Timmerman H (1998) The histamine H3 receptor; a target for new drugs, 1st edn. Elsevier, Amsterdam, p 177
-
(1998)
The Histamine H3 Receptor; a Target for New Drugs, 1st Edn.
, pp. 177
-
-
Leurs, R.1
Blandina, P.2
Tedford, C.3
Timmerman, H.4
-
50
-
-
34247209676
-
Development of a practical synthesis of STA-5312, a novel indolizine oxalylamide microtubule inhibitor
-
Li H, Xia Z, Chen S, Koya K, Ono M, Sun L (2007) Development of a practical synthesis of STA-5312, a novel indolizine oxalylamide microtubule inhibitor. Org Process Res Dev 11:246-250
-
(2007)
Org Process Res Dev
, vol.11
, pp. 246-250
-
-
Li, H.1
Xia, Z.2
Chen, S.3
Koya, K.4
Ono, M.5
Sun, L.6
-
51
-
-
0007421690
-
-
Lindsay R, Dempster DW Jordan VC Estrogens and Antiestrogen, Lippincott-Raven, Philadelphia
-
Lobo RA (1997) The post menopausal state and estrogen deficiency. In: Lindsay R, Dempster DW Jordan VC Estrogens and Antiestrogen, Lippincott-Raven, Philadelphia, pp 63-72
-
(1997)
The Post Menopausal State and Estrogen Deficiency
, pp. 63-72
-
-
Lobo, R.A.1
-
52
-
-
84855990692
-
Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents
-
Lv H, Ren J, Ma S, Xu S, Qu J, Liu Z, Zhou Q, Chen X, Yu S (2012) Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents. PLoS ONE 7(1):e30342
-
(2012)
PLoS ONE
, vol.7
, Issue.1
-
-
Lv, H.1
Ren, J.2
Ma, S.3
Xu, S.4
Qu, J.5
Liu, Z.6
Zhou, Q.7
Chen, X.8
Yu, S.9
-
53
-
-
0028021758
-
SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation
-
Mackenzie B, Panayotova-Heiermann M, Loo DD, Lever JE, Wright EM (1994) SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation. J Biol Chem 269(36):22488-22491
-
(1994)
J Biol Chem
, vol.269
, Issue.36
, pp. 22488-22491
-
-
Mackenzie, B.1
Panayotova-Heiermann, M.2
Loo, D.D.3
Lever, J.E.4
Wright, E.M.5
-
54
-
-
85047724452
-
Indolizine derivatives and the use thereof as antidiabetics
-
US Patent 8,106,067 B2, Jan 31, 2012
-
Mederski W, Beier N, Burgdorf LT, Gericke R, Klein M, Tsaklakidis C (2012) Indolizine derivatives and the use thereof as antidiabetics. US Patent 8,106,067 B2, Jan 31, 2012
-
(2012)
-
-
Mederski, W.1
Beier, N.2
Burgdorf, L.T.3
Gericke, R.4
Klein, M.5
Tsaklakidis, C.6
-
55
-
-
0020104282
-
Interactions of molecules with nucleic acids VI Computer design of chromophoric intercalating agents
-
Miller KJ, Newlin DD (1982) Interactions of molecules with nucleic acids VI Computer design of chromophoric intercalating agents. Biopolymers 21(3):633-652
-
(1982)
Biopolymers
, vol.21
, Issue.3
, pp. 633-652
-
-
Miller, K.J.1
Newlin, D.D.2
-
56
-
-
0036310281
-
Novel potent substance P and neurokinin A receptor antagonists. Conception, synthesis and biological evaluation of indolizine derivatives
-
DOI 10.1016/S0968-0896(02)00144-X, PII S096808960200144X
-
Millet R, Domarkas J, Rigo B, Goossens L, Goossens JF, Houssin R, Henichart JP (2002) Novel potent substance P and neurokinin A receptor antagonists Conception, synthesis and biological evaluation of indolizine derivatives. Bioorg Med Chem 10(9):2905-2912 (Pubitemid 34763824)
-
(2002)
Bioorganic and Medicinal Chemistry
, vol.10
, Issue.9
, pp. 2905-2912
-
-
Millet, R.1
Domarkas, J.2
Rigo, B.3
Goossens, L.4
Goossens, J.-F.5
Houssin, R.6
Henichart, J.-P.7
-
58
-
-
0024399696
-
DNA - drug interactions. The crystal structure of d(CGATCG) complexed with daunomycin
-
DOI 10.1016/0022-2836(89)90577-9
-
Moore MH, Hunter WN, d'Estaintot BL, Kennard O (1989) DNA-drug interactions The crystal structure of d(CGATCG):complexed with daunomycin. J Mol Biol 206(4):693-705 (Pubitemid 19137423)
-
(1989)
Journal of Molecular Biology
, vol.206
, Issue.4
, pp. 693-705
-
-
Moore, M.H.1
Hunter, W.N.2
Langlois D'Estaintot, B.3
Kennard, O.4
-
59
-
-
0021930875
-
Isolation of A58365A and A58365B, angiotensin converting enzyme inhibitors produced by Streptomyces chromofuscus
-
Mynderse JS, Samlaska SK, Fukuda DS, Du Bus RH, Baker PJ (1985) Isolation of A58365A and A58365B, angiotensin converting enzyme inhibitors produced by Streptomyces chromofuscus. J Antibiot 38(8):1003-1007 (Pubitemid 15246221)
-
(1985)
Journal of Antibiotics
, vol.38
, Issue.8
, pp. 1003-1007
-
-
Mynderse, J.S.1
Samlaska, S.K.2
Fukuda, D.S.3
-
60
-
-
0032555109
-
Inhibition of lipid peroxidation mediated by indolizines
-
DOI 10.1016/S0960-894X(98)00313-8, PII S0960894X98003138
-
Nasir AI, Gundersen LL, Rise F, Antonsen O, Kristensen T, Langhelle B, Bast A, Custers I, Haenen GR, Wikstrom H (1998) Inhibition of lipid peroxidation mediated by indolizines. Bioorg Med Chem Lett 8(14):1829-1832 (Pubitemid 28338001)
-
(1998)
Bioorganic and Medicinal Chemistry Letters
, vol.8
, Issue.14
, pp. 1829-1832
-
-
Nasir, A.I.1
Gundersen, L.-L.2
Rise, F.3
Antonsen, O.4
Kristensen, T.5
Langhelle, B.6
Bast, A.7
Custers, I.8
Haenen, G.R.M.M.9
Wikstrom, H.10
-
61
-
-
0032734864
-
A novel combretastatin A-4 derivative, AC-7700, shows marked antitumor activity against advanced solid tumors and orthotopically transplanted tumors
-
Nihei Y, Suga Y, Morinaga Y, Ohishi K, Okano A, Ohsumi K, Hatanaka T, Nakagawa R, Tsuji T, Akiyama Y, Saito S, Hori K, Sato Y, Tsuruo T (1999) A novel combretastatin A-4 derivative, AC-7700, shows marked antitumor activity against advanced solid tumors and orthotopically transplanted tumors. Jpn J Cancer Res 90(9):1016-1025 (Pubitemid 29500443)
-
(1999)
Japanese Journal of Cancer Research
, vol.90
, Issue.9
, pp. 1016-1025
-
-
Nihei, Y.1
Suga, Y.2
Morinaga, Y.3
Ohishi, K.4
Okano, A.5
Ohsumi, K.6
Hatanaka, T.7
Nakagawa, R.8
Tsuji, T.9
Akiyama, Y.10
Saito, S.11
Hori, K.12
Sato, Y.13
Tsuruo, T.14
-
62
-
-
79952046107
-
Antimicrobial and antimutagenic properties of newly synthesized derivatives of indolizine
-
Olejnikova P, Birosova L, Svorc L (2009) Antimicrobial and antimutagenic properties of newly synthesized derivatives of indolizine. Sci Pharm 77:216
-
(2009)
Sci Pharm
, vol.77
, pp. 216
-
-
Olejnikova, P.1
Birosova, L.2
Svorc, L.3
-
63
-
-
34247251290
-
Synthesis and evaluation of 1-deoxy-8-epi-castanospermine, 1-deoxy-8-hydroxymethyl castanospermine, and (6S,7S,8R,8aR)-8-amino- octahydroindolizine-6,7-diol
-
DOI 10.1016/j.tet.2007.03.085, PII S0040402007005029
-
Pandey G, Dumbre SG, Pal S, Khan MI, Shabab M (2007) Synthesis and evaluation of 1-deoxy-8-epi-castanospermine, 1-deoxy-8-hydroxymethyl castanospermine, and(6S,7S,8R,8aR)-8-amino-octahydroindolizine-6,7-diol. Tetrahedron 63(22):4756-4761 (Pubitemid 46627800)
-
(2007)
Tetrahedron
, vol.63
, Issue.22
, pp. 4756-4761
-
-
Pandey, G.1
Dumbre, S.G.2
Pal, S.3
Khan, M.I.4
Shabab, M.5
-
64
-
-
0027312537
-
Indolizine 5α-reductase inhibitors
-
Patent Evaluation
-
Patent Evaluation (1993) Indolizine 5α-reductase inhibitors. Expert Opin Ther Pat 3(5):597-599
-
(1993)
Expert Opin Ther Pat
, vol.3
, Issue.5
, pp. 597-599
-
-
-
66
-
-
3142729057
-
Gimatecan, a novel camptothecin with a promising preclinical profile
-
DOI 10.1097/01.cad.0000131687.08175.14
-
Pratesi G, Beretta GL, Zunino F (2004) Gimatecan, a novel camptothecin with a promising preclinical profile. Anticancer Drugs 15(6):545-552 (Pubitemid 38932320)
-
(2004)
Anti-Cancer Drugs
, vol.15
, Issue.6
, pp. 545-552
-
-
Pratesi, G.1
Beretta, G.L.2
Zunino, F.3
-
67
-
-
84879684485
-
New thiazolidinyl analogs containing pyridine ring: Synthesis, biological evaluation and QSAR studies
-
Ranga R, Sharma V, Kumar V (2013) New thiazolidinyl analogs containing pyridine ring: synthesis, biological evaluation and QSAR studies. Med Chem Res 22(4):1538-1548
-
(2013)
Med Chem Res
, vol.22
, Issue.4
, pp. 1538-1548
-
-
Ranga, R.1
Sharma, V.2
Kumar, V.3
-
68
-
-
77953001158
-
Biological importance of the indole nucleus in recent years: A comprehensive review
-
Sharma V, Kumar P, Pathak D (2010) Biological importance of the indole nucleus in recent years: a comprehensive review. J Het Chem 47:491-502
-
(2010)
J Het Chem
, vol.47
, pp. 491-502
-
-
Sharma, V.1
Kumar, P.2
Pathak, D.3
-
69
-
-
84876707914
-
Heterocyclic chalcone analogues as potential anticancer agents
-
Sharma V, Kumar V, Kumar P (2013) Heterocyclic chalcone analogues as potential anticancer agents. Anticancer Agents Med Chem 13:422-432
-
(2013)
Anticancer Agents Med Chem
, vol.13
, pp. 422-432
-
-
Sharma, V.1
Kumar, V.2
Kumar, P.3
-
70
-
-
77954348728
-
Synthesis and antiproliferative activity of indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line
-
Shen YM, Lv PC, Chen W, Liu PG, Zhang MZ, Zhu HL (2010) Synthesis and antiproliferative activity of indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line. Eur J Med Chem 45(7):3184-3190
-
(2010)
Eur J Med Chem
, vol.45
, Issue.7
, pp. 3184-3190
-
-
Shen, Y.M.1
Lv, P.C.2
Chen, W.3
Liu, P.G.4
Zhang, M.Z.5
Zhu, H.L.6
-
71
-
-
41549096283
-
TD-DFT investigation on the electronic spectra of novel N-methylmaleimides linked with indolizine ring system
-
Shigemitsu Y, Komiya K, Mizuyama N, Tominaga Y (2008) TD-DFT investigation on the electronic spectra of novel N-methylmaleimides linked with indolizine ring system. THEOCHEM 855 (1-3):92-101
-
(2008)
THEOCHEM
, vol.855
, Issue.1-3
, pp. 92-101
-
-
Shigemitsu, Y.1
Komiya, K.2
Mizuyama, N.3
Tominaga, Y.4
-
72
-
-
36849041524
-
Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors
-
DOI 10.1248/bpb.30.2365
-
Shiose Y, Ochi Y, Kuga H, Yamashita F, Hashida M (2007) Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors. Biol Pharm Bull 30(12):2365-2370 (Pubitemid 350223744)
-
(2007)
Biological and Pharmaceutical Bulletin
, vol.30
, Issue.12
, pp. 2365-2370
-
-
Shiose, Y.1
Ochi, Y.2
Kuga, H.3
Yamashita, F.4
Hashida, M.5
-
73
-
-
34250677715
-
A novel synthesis of highly substituted perhydropyrrolizines, perhydroindolizines, and pyrrolidines: Inhibition of the peptidyl-prolyl cis/trans isomerase (PPIase) Pin1
-
DOI 10.1002/hlca.200790028
-
Siegrist R, Zürcher M, Baumgartner C, Seiler P, Diederich F, Daum S, Fischer G, Klein C, Dangl M, Schwaiger MA (2007) Novel synthesis of highly substituted perhydropyrrolizines, perhydroindolizines, and pyrrolidines: inhibition of the peptidyl-prolyl cis/trans isomerase(PPIase):pin1. Helv Chim Acta 90(2):217-259 (Pubitemid 46931558)
-
(2007)
Helvetica Chimica Acta
, vol.90
, Issue.2
, pp. 217-259
-
-
Siegrist, R.1
Zurcher, M.2
Baumgartner, C.3
Seiler, P.4
Diederich, F.5
Daum, S.6
Fischer, G.7
Klein, C.8
Dangl, M.9
Schwaiger, M.10
-
74
-
-
0027211068
-
Tissue-specific promoters regulate aromatase cytochrome P450 expression
-
Simpson ER, Mahendroo MS, Means GD, Kilgore MW, Jo Corbin C, Mendelson CR (1993) Tissue-specific promoters regulate aromatase cytochrome P450 expression. J Steroid Biochem Mol Biol 44(4):321-330 (Pubitemid 23126602)
-
(1993)
Journal of Steroid Biochemistry and Molecular Biology
, vol.44
, Issue.4-6
, pp. 321-330
-
-
Simpson, E.R.1
Mahendroo, M.S.2
Means, G.D.3
Kilgore, M.W.4
Corbin, C.J.5
Mendelson, C.R.6
-
75
-
-
80054926247
-
Recent progress in synthesis and bioactivity studies of indolizines
-
Singh GS, Mmatli EE (2011) Recent progress in synthesis and bioactivity studies of indolizines. Eur J Med Chem 46(11):5237-5257
-
(2011)
Eur J Med Chem
, vol.46
, Issue.11
, pp. 5237-5257
-
-
Singh, G.S.1
Mmatli, E.E.2
-
76
-
-
0036182501
-
Bacopasaponin C: Critical evaluation of anti-leishmanial properties in various delivery modes
-
DOI 10.1080/107175402753413181
-
Sinha J, Raay B, Das N, Medda S, Garai S, Mahato SB, Basu MK (2002) Bacopasaponin C: critical evaluation of anti-leishmanial properties in various delivery modes. Drug Deliv 9(1):55-62 (Pubitemid 34171335)
-
(2002)
Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents
, vol.9
, Issue.1
, pp. 55-62
-
-
Sinha, J.1
Raay, B.2
Das, N.3
Medda, S.4
Garai, S.5
Mahato, S.B.6
Basu, M.K.7
-
77
-
-
84896520354
-
Plant derived anticancer agents: A review
-
Sisodiya PS (2013) Plant derived anticancer agents: a review. Int J Res Dev Pharm L Sci 2(2):293-308
-
(2013)
Int J Res Dev Pharm L Sci
, vol.2
, Issue.2
, pp. 293-308
-
-
Sisodiya, P.S.1
-
78
-
-
11244292512
-
Herbicidal indolizine-5,8-diones: Phostosytem I redox mediators
-
DOI 10.1002/ps.980
-
Smith SC, Clarke ED, Ridley SM, Bartlett D, Greenhow DT, Glithro H, Klong AY, Mitchell G, Mullier GW (2005) Herbicidal indolizine-5,8-diones: photosystem I redox mediators. Pest Manag Sci 61(1):16-24 (Pubitemid 40065144)
-
(2005)
Pest Management Science
, vol.61
, Issue.1
, pp. 16-24
-
-
Smith, S.C.1
Clarke, E.D.2
Ridley, S.M.3
Bartlett, D.4
Greenhow, D.T.5
Glithro, H.6
Klong, A.Y.7
Mitchell, G.8
Mullier, G.W.9
-
79
-
-
0034119301
-
New aromatase inhibitors. Synthesis and biological activity of aryl- substituted pyrrolizine and indolizine derivatives
-
DOI 10.1016/S0968-0896(00)00024-9, PII S0968089600000249
-
Sonnet P, Dallemagne P, Guillon J, Enguehard C, Stiebing S, Tanguy J, Bureau R, Rault S, Auvray P, Moslemi S, Sourdaine P, Seralini GE (2000) New aromatase inhibitors synthesis and biological activity of aryl-substituted pyrrolizine and indolizine derivatives. Bioorg Med Chem 8(5):945-955 (Pubitemid 30336391)
-
(2000)
Bioorganic and Medicinal Chemistry
, vol.8
, Issue.5
, pp. 945-955
-
-
Sonnet, P.1
Dallemagne, P.2
Guillon, J.3
Enguehard, C.4
Stiebing, S.5
Tanguy, J.6
Bureau, R.7
Rault, S.8
Auvray, P.9
Moslemi, S.10
Sourdaine, P.11
Seralini, G.-E.12
-
80
-
-
0029060066
-
Combined estrogen and progestin hormone replacement therapy in relation to risk of breast cancer in middle-aged women
-
Stanford JL, Weiss NS, Voigt LF, Daling JR, Habel LA, Rossing MA (1995) Combined estrogen and progestin hormone replacement therapy in relation to risk of breast cancer in middle-aged women. JAMA 274(2):137-142
-
(1995)
JAMA
, vol.274
, Issue.2
, pp. 137-142
-
-
Stanford, J.L.1
Weiss, N.S.2
Voigt, L.F.3
Daling, J.R.4
Habel, L.A.5
Rossing, M.A.6
-
81
-
-
16344376901
-
Indolizine 1-sulfonates as potent inhibitors of 15-lipoxygenase from soybeans
-
DOI 10.1016/j.bmc.2005.02.056
-
Teklu S, Gundersen LL, Larsen T, Malterud KE, Rise F (2005) Indolizine 1-sulfonates as potent inhibitors of 15-lipoxygenase from soybeans. Bioorg Med Chem 13(9):3127-3139 (Pubitemid 40467563)
-
(2005)
Bioorganic and Medicinal Chemistry
, vol.13
, Issue.9
, pp. 3127-3139
-
-
Teklu, S.1
Gundersen, L.-L.2
Larsen, T.3
Malterud, K.E.4
Rise, F.5
-
84
-
-
77953377264
-
Indolizine studies, part 5: Indolizine-2-carboxamides as potential hiv-1 protease inhibitors
-
Tukulula M, Klein R, Kaye PT (2010) Indolizine studies, part 5: indolizine-2-carboxamides as potential hiv-1 protease inhibitors. Synth Commun 40(13):2018-2028
-
(2010)
Synth Commun
, vol.40
, Issue.13
, pp. 2018-2028
-
-
Tukulula, M.1
Klein, R.2
Kaye, P.T.3
-
85
-
-
84904413860
-
Drugs in clinical development for lung cancer: Summary and table
-
Unknown
-
Unknown (2013) Drugs in clinical development for lung cancer: summary and table. Pharm Med 27(2):95-127
-
(2013)
Pharm Med
, vol.27
, Issue.2
, pp. 95-127
-
-
-
86
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
DOI 10.1016/j.biocel.2006.07.001, PII S1357272506002196
-
Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem 39(1):44-84 (Pubitemid 44566469)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.1
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.D.4
Mazur, M.5
Telser, J.6
-
87
-
-
0025872840
-
Centrally-mediated antinociceptive action of RWJ-22757 (formerly McN-5195): Involvement of spinal descending inhibitory pathways (a hypothesis)
-
Vaught JL, Raffa RB (1991) Centrally-mediated antinociceptive action of RWJ-22757 (formerly McN-5195): involvement of spinal descending inhibitory pathways (a hypothesis). Life Sci 48(23):2233-2241
-
(1991)
Life Sci
, vol.48
, Issue.23
, pp. 2233-2241
-
-
Vaught, J.L.1
Raffa, R.B.2
-
88
-
-
0025186255
-
Antinociceptive action of McN-5195 in rodents: A structurally novel (indolizine) analgesic with a nonopioid mechanism of action
-
Vaught JL, Carson JR, Carmosin RJ, Blum PS, Persico FJ, Hageman WE, Shank RP, Raffa RB (1990) Antinociceptive action of McN-5195 in rodents: a structurally novel (indolizine) analgesic with a nonopioid mechanism of action. J Pharmacol Exp Ther 255(1):1-10 (Pubitemid 20361474)
-
(1990)
Journal of Pharmacology and Experimental Therapeutics
, vol.255
, Issue.1
, pp. 1-10
-
-
Vaught, J.L.1
Carson, J.R.2
Carmosin, R.J.3
Blum, P.S.4
Persico, F.J.5
Hageman, W.E.6
Shank, R.P.7
Raffa, R.B.8
-
89
-
-
80355138841
-
Indolizine derivatives: Recent advances and potential pharmacological activities
-
Vemula V, Vurukonda S, Bairi C (2011) Indolizine derivatives: recent advances and potential pharmacological activities Int J Pharm Sci Rev Res 11:159-163
-
(2011)
Int J Pharm Sci Rev Res
, vol.11
, pp. 159-163
-
-
Vemula, V.1
Vurukonda, S.2
Bairi, C.3
-
90
-
-
33845375889
-
Indolizines 2 Preparation of 1- and 3-indolizinols and their esters
-
Wadsworth DH, Bender SL, Smith DL, Luss HR, Weidner CH (1986) Indolizines 2 Preparation of 1- and 3-indolizinols and their esters. J Org Chem 51(24):4639-4644
-
(1986)
J Org Chem
, vol.51
, Issue.24
, pp. 4639-4644
-
-
Wadsworth, D.H.1
Bender, S.L.2
Smith, D.L.3
Luss, H.R.4
Weidner, C.H.5
-
91
-
-
0000792758
-
Indolizines 3 Oxidation products of indolizinols: Radicals, ions, and oxidized dimers
-
Wadsworth DH, Weidner CH, Bender SL, Nuttall RH, Luss HR (1989) Indolizines 3 Oxidation products of indolizinols: radicals, ions, and oxidized dimers. J Org Chem 54(15):3652-3660
-
(1989)
J Org Chem
, vol.54
, Issue.15
, pp. 3652-3660
-
-
Wadsworth, D.H.1
Weidner, C.H.2
Bender, S.L.3
Nuttall, R.H.4
Luss, H.R.5
-
92
-
-
7144248725
-
Plant antitumor agents 1 The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminate
-
Wall ME, Wani MC, Cook CE, Palmer KH, McPhail HT, Sim GA (1966) Plant antitumor agents 1 The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminate. J Am Chem Soc 88:3888-3890
-
(1966)
J Am Chem Soc
, vol.88
, pp. 3888-3890
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
Palmer, K.H.4
McPhail, H.T.5
Sim, G.A.6
-
93
-
-
27744514053
-
3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors
-
DOI 10.1016/j.bmcl.2005.09.051, PII S0960894X05012205
-
Weide T, Arve L, Prinz H, Waldmann H, Kessler H (2006) 3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors. Bioorg Med Chem Lett 16(1):59-63 (Pubitemid 41625641)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.1
, pp. 59-63
-
-
Weide, T.1
Arve, L.2
Prinz, H.3
Waldmann, H.4
Kessler, H.5
-
94
-
-
0001508446
-
Indolizines 4 dyes derived from oxoindolizinium ions and active methylene compounds
-
Weidner CH, Wadsworth DH, Bender SL, Beltman DJ (1989) Indolizines 4 dyes derived from oxoindolizinium ions and active methylene compounds. J Org Chem 54(15):3660-3664
-
(1989)
J Org Chem
, vol.54
, Issue.15
, pp. 3660-3664
-
-
Weidner, C.H.1
Wadsworth, D.H.2
Bender, S.L.3
Beltman, D.J.4
-
95
-
-
0001008297
-
Indolizines 5 preparation and structural assignments of azaindolizinols
-
Weidner CH, Michaels FM, Beltman DJ, Montgomery CJ, Wadsworth DH, Briggs BT, Picone ML (1991) Indolizines 5 preparation and structural assignments of azaindolizinols. J Org Chem 56(19):5594-5598
-
(1991)
J Org Chem
, vol.56
, Issue.19
, pp. 5594-5598
-
-
Weidner, C.H.1
Michaels, F.M.2
Beltman, D.J.3
Montgomery, C.J.4
Wadsworth, D.H.5
Briggs, B.T.6
Picone, M.L.7
-
96
-
-
78649505322
-
A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells
-
Wu N, Wu XW, Agama K, Pommier Y, Du J, Li D, Gu LQ, Huang ZS, An LK (2010) A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells. Biochemistry 49(47):10131-10136
-
(2010)
Biochemistry
, vol.49
, Issue.47
, pp. 10131-10136
-
-
Wu, N.1
Wu, X.W.2
Agama, K.3
Pommier, Y.4
Du, J.5
Li, D.6
Gu, L.Q.7
Huang, Z.S.8
An, L.K.9
-
97
-
-
0032940930
-
2-independent mechanisms
-
DOI 10.1016/S1388-1981(99)00053-0, PII S1388198199000530
-
Yokota Y, Hanasaki K, Ono T, Nakazato H, Kobayashi T, Arita H (1999) Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms. Biochim Biophys Acta 1438(2):213-222 (Pubitemid 29236127)
-
(1999)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1438
, Issue.2
, pp. 213-222
-
-
Yokota, Y.1
Hanasaki, K.2
Ono, T.3
Nakazato, H.4
Kobayashi, T.5
Arita, H.6
-
98
-
-
13844319812
-
Magic bullets and tuberculosis drug targets
-
Zhang Y (2005) Magic bullets and tuberculosis drug targets. Annu Rev Pharmacool Toxicol 45:529-564
-
(2005)
Annu Rev Pharmacool Toxicol
, vol.45
, pp. 529-564
-
-
Zhang, Y.1
-
99
-
-
28844485982
-
Phosphodiesterase-4 as a potential drug target
-
DOI 10.1517/14728222.9.6.1283
-
Zhang KY, Ibrahim PN, Gillette S, Bollag G (2005) Phosphodiesterase-4 as a potential drug target. Expert Opin Ther Targets 9(6):1283-1305 (Pubitemid 41762878)
-
(2005)
Expert Opinion on Therapeutic Targets
, vol.9
, Issue.6
, pp. 1283-1305
-
-
Zhang, K.Y.J.1
Ibrahim, P.N.2
Gillette, S.3
Bollag, G.4
-
100
-
-
84862534440
-
Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors
-
Zhu L, Zhang X, Lei N, Liu W, Miao Z, Zhuang C, Sheng C, Guo W, Dong G, Yao J, Cheng P, Zhang W (2012) Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors. Chem Biodivers 9(6):1084-1094
-
(2012)
Chem Biodivers
, vol.9
, Issue.6
, pp. 1084-1094
-
-
Zhu, L.1
Zhang, X.2
Lei, N.3
Liu, W.4
Miao, Z.5
Zhuang, C.6
Sheng, C.7
Guo, W.8
Dong, G.9
Yao, J.10
Cheng, P.11
Zhang, W.12
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